Targeted Drug Delivery: Innovations to Overcome Biological and Technical Barriers
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 61
Special Issue Editors
Interests: molecular modeling; cheminformatic; natural products
Special Issues, Collections and Topics in MDPI journals
Interests: QSAR; medicinal chemistry; natural products; cheminformatic
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The field of drug delivery faces several challenges that stem from the complexity of both human biology and pharmaceutical technology. Target specificity is one of the biggest challenges in ensuring that drugs reach the intended target, such as specific tissues or cells, without affecting other areas of the body. This is especially crucial in treatments like chemotherapy, where non-specific delivery can damage healthy tissues. The challenges in drug delivery discussed in this Special Issue include the following: efficient solutions in the human body and various defense mechanisms, like the blood–brain barrier; stability during storage, transport, and administration, requiring innovative formulations; delivery systems, such as injectables or inhalers that may pose challenges for patients, impacting the efficacy of treatment; developing and manufacturing advanced drug delivery systems, such as nanoparticles or personalized medicine, which can be prohibitively expensive and difficult to scale for widespread use; and drug resistance, which can render delivery systems ineffective.
Researchers are continually innovating to address these challenges, exploring strategies such as nanotechnology, controlled-release systems, and biomimetic approaches in their search for solutions that facilitate more effective and safer drug delivery methods. We look forward to receiving your contributions.
Dr. Luciana Scotti
Dr. Marcus Tullius Scotti
Guest Editors
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Keywords
- drug delivery
- biological barriers
- drug stability
- patient compliance
- resistance
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