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Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Extracellular Vesicle-Based Delivery System for Cancer and Neurodegenerative Disease Treatment

edited by Eva Costanzi,

Stefano Persano

and

Stefano Leporatti

submission deadline 15 Jul 2026 | 2 articles | Viewed by 4502 | Submission Open

Keywords: extracellular vesicles; liposomes; cancer; neurodegenerative diseases; immunotherapy; mRNA delivery; drug delivery system; therapeutics

(This special issue belongs to the Section Gene and Cell Therapy)

Biomaterial-Based Nanoencapsulation Systems for Drug Protection and Controlled Release

edited by

Oscar E. Pérez

submission deadline 20 Jul 2026 | 4 articles | Viewed by 3438 | Submission Open

Keywords: nanostructures; nanoencapsulation; drugs/bioactive compounds; biopolymer materials; controlled release; bioavailability; nanoproducts

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Biomaterials and Agents: Pharmaceutical and Biomedical Applications in Dental and Orthopedic Research

edited by

Božana Petrović

and Vukoman R. Jokanović

submission deadline 20 Jul 2026 | 1 articles | Viewed by 1299 | Submission Open

Keywords: biomaterials; dental and orthopedic applications; regenerative medicine; nanotechnology; 3D printing; drug delivery systems

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Dosage Form Design and Delivery Therapy for Skin Disorders

edited by

Luana Mota Ferreira

and

Marcel Henrique Marcondes Sari

submission deadline 30 Jul 2026 | 3 articles | Viewed by 6638 | Submission Open

Keywords: skin therapy; skin dosage forms; skin delivery; formulations design; natural agents; polysaccharides; vegetable oils; bioactive compounds; antioxidant activity; anti-inflammatory activity; antimicrobial effect; dosage safety and efficacy

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Targeting Protein Aggregation and Degradation in Age-Related Diseases

edited by Martín Hugo and

Javier Garcia-Pardo

submission deadline 30 Jul 2026 | Viewed by 404 | Submission Open

Keywords: aging; aggregation inhibitor; alzheimer disease; amyloidoses; antioxidant compounds; anti-inflammatory; autophagy; α -synucleinopathies; cell signaling; cysteine; drug delivery; drug discovery; high-throughput screening; nanotechnology; neurodegenerative diseases; oxidation; parkinson’ s disease; phase separation; protease inhibitor; proteasome; proteostasis; protein aggregation; redox; stress granule

(This special issue belongs to the Section Drug Targeting and Design)

Chitosan-Based Nanoparticles as Carriers for Drug Delivery and Biomedical Applications

edited by Aline Martins dos Santos, Leonardo Miziara Barboza Ferreira and Eleonora Maretti

submission deadline 31 Jul 2026 | 3 articles | Viewed by 6403 | Submission Open

Keywords: chitosan; nanoparticles; pre-formulation; drug delivery; anti-cancer; anti-inflammatory; biomedical applications

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Optimizing Drug Therapy in Kidney Diseases: Effectiveness and Safety

edited by

Pedro Dorado

Miłosz Miedziaszczyk

and Ilona Idasiak-Piechocka

submission deadline 31 Jul 2026 | 3 articles | Viewed by 4760 | Submission Open

Keywords: drug– drug interactions; pharmacotherapy of kidney diseases; immunosuppression; drug-induced nephrotoxicity; glomerulonephritis; kidney transplantation; hemodialysis; peritoneal dialysis; vasculitis

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Pharmaceutical Compounding and Development of Advanced Therapy Medicinal Products: From Bench to Bedside

edited by

Edwin Bremer

Bahez Gareb

and Hugo Calderón

submission deadline 31 Jul 2026 | 1 articles | Viewed by 3352 | Submission Open

Keywords: ATMPs; manufacturing process; pharmaceutical compounding; product development; product characterization; process optimization; tech transfer; analytical procedures; qualification; validation; mechanism of action; CAR T cells; TILs; (viral) vectors; cell banking; regulatory aspects; hospital exemption; donor variability; comparability; point-of-care; allogenic/autologous; reconstitution/preparation for administration

(This special issue belongs to the Section Clinical Pharmaceutics)

Drug Formulations Based on Chitosan and Its Derivatives for Therapeutic Applications

edited by

Mohammed Balogun

and Zamani Cele

submission deadline 31 Jul 2026 | 1 articles | Viewed by 1003 | Submission Open

Keywords: chitosan; chitosan derivatives; chemical modification; drug delivery biopolymers; biomedicines drug formulations

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Nanomedicine and Nanotechnology: Recent Advances and Applications

edited by

Wei Wu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 962 | Submission Open

Keywords: novel drug delivery systems engineered for spatial-temporal control; nanodiagnostics integrating sensing; imaging; and therapy; mechanistic studies addressing biocompatibility; toxicity; and regulatory pathways; scalable manufacturing strategies bridging laboratory innovation to clinical practice

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Advanced Materials Science and Technology in Drug Delivery, 2nd Edition

edited by

Ionela Andreea Neacsu

submission deadline 31 Jul 2026 | 1 articles | Viewed by 912 | Submission Open

Keywords: nanomaterials; metal– organic frameworks (MOFs); hybrid and polymer-lipid nanoparticles; hydrogels (injectable; responsive); polymers (natural: chitosan; hyaluronic acid; and dextrin synthetic: PEG; PCL; and PLA); stimuli-responsive/bioresponsive drug delivery (pH; temperature; enzymatic; redox; magnetic; and light-triggered); site-specific delivery (e.g.; tumor; brain; oral; and mucosal); imaging-guided or theranostic drug delivery; co-delivery systems (simultaneous delivery of multiple drugs or agents); surface modification/functionalization of carriers; ligand/receptor targeting (e.g.; folic acid; peptides; and antibodies); encapsulation and loading efficiency; microfluidic-based formulation

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Mucosal Drug Delivery: Exploring Novel Approaches and Formulations

edited by

Kunn Hadinoto Ong

submission deadline 31 Jul 2026 | Viewed by 468 | Submission Open

Keywords: drug delivery; bioavailability; enhanced drug permeation; formulations

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Drug Stability in Oral Administration

edited by

Thilini Thrimawithana

and

Ayman Allahham

submission deadline 31 Jul 2026 | Viewed by 406 | Submission Open

Keywords: drug stability; oral drug delivery; in vitro assessment; dissolution; oral medication lubricants; nano-formulations; biologics; stability enhancement; real-time stability assessment; drug release kinetics

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Anticancer Nanotherapeutics for Lung Cancer Therapy

edited by

Zhengwei Huang

, Xialin Dai and Yanjuan Huang

submission deadline 31 Jul 2026 | Viewed by 35 | Submission Open

Keywords: lung cancer; nanotherapeutics; nanoparticles; liposomes; polymeric micelles; nanogels; targeting nanosystems; pulmonary delivery

(This special issue belongs to the Section Drug Delivery and Controlled Release)

3D Printing and Personalized Medicine: Advancing Drug Delivery Systems

edited by

Hyun-Ouk Kim

and Abdullah Alzahrani

submission deadline 31 Jul 2026 | Submission Open

Keywords: 3D printing; personalized medicine; additive manufacturing; fused deposition modeling (FDM); hot-melt extrusion (HME); solid dosage forms; tailored drug release; in silico formulation; quality-by-design (QbD); digital pharmaceutics

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Research on Protein-Based Nanoparticles and Their Pharmaceutical Applications

edited by

Mouhamad Khoder

and Hachemi Kadri

submission deadline 10 Aug 2026 | 1 articles | Viewed by 1269 | Submission Open

Keywords: nanoparticles; protein; protein derivatives; targeted delivery; therapeutics; diagnostics

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Drug Delivery for Natural Extract Applications

edited by

Nada Ćujić Nikolić

Katarina Šavikin

, Milica Radan and Jelena Mudrić

submission deadline 20 Aug 2026 | 4 articles | Viewed by 7981 | Submission Open

Keywords: natural-based extracts; natural-based products; bioactive compounds; optimization of extraction; green and conventional extraction methods; by-product; waste; unexploited; underutilized products; antioxidants; biological activities; mode of action; encapsulation; carriers and biopolymers; drug delivery system; therapeutics

(This special issue belongs to the Section Biopharmaceutics)

Innovative Biomaterials for Precise Drug Delivery

edited by

Anna Drabczyk

and

Sonia Kudłacik-Kramarczyk

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1299 | Submission Open

Keywords: drug delivery vehicles; theranostic drug delivery systems; stimuli-responsive systems; liposomes; microspheres; oleogels; organogels; emulsion-based drug carriers; core– shell systems with drug delivery functions

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Research on the Design and Development of Anti-Tumor Drug Delivery Vehicles

edited by

Mengze Xu

submission deadline 20 Aug 2026 | Viewed by 369 | Submission Open

Keywords: anti-tumor drugs; drug delivery vehicles; nanoparticles; cancer treatment; targeted therapy; drug efficacy; delivery system optimization; tumor microenvironment; neurocognitive aspects; drug design

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Advances in Emulsifying Drug Delivery Systems

edited by Lissinda Hester Du Plessis and

Joe Viljoen

submission deadline 25 Aug 2026 | 3 articles | Viewed by 2791 | Submission Open

Keywords: characterization; dosage form; lipophilic drug delivery systems; lipophilic drugs; permeability; emulsifying drug delivery systems; self-emulsification; solubility

(This special issue belongs to the Section Drug Delivery and Controlled Release)

ROS-Mediated Nano Drug Delivery for Antitumor Therapy

edited by Yanjuan Huang and Xiaoyu Xu

submission deadline 28 Aug 2026 | 3 articles | Viewed by 5466 | Submission Open

Keywords: antitumor therapy; reactive oxygen species (ROS); ROS-mediated biomedical nanotechnology; ROS-responsive nano drug delivery; ROS-mediated immunotherapy; ROS-mediated combination therapy; oxidation therapy; photodynamic therapy (PDT); sonodynamic therapy (SDT); chemodynamic therapy (CDT); radiodynamic therapy (RDT); microdynamic therapy (MDT); electrodynamic therapy (EDT)

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Development of Vectors for Drug and Gene Delivery via the Nasal Route

edited by Flávia Nathiely Silveira Fachel and Roselena Silvestri Schuh

submission deadline 31 Aug 2026 | 2 articles | Viewed by 3273 | Submission Open

Keywords: nasal route; nose-to-brain; nanotechnology-based delivery systems; nanoparticles; nanoemulsions; liposomes; viral vectors; nonviral vectors; mucoadhesive polymers; permeation enhancers; transmucosal delivery

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Recent Advances in Cocrystal and Nano-Cocrystal Technologies for Pharmaceutical and Nutraceutical Applications

edited by Jiamei Chen

submission deadline 31 Aug 2026 | 2 articles | Viewed by 2855 | Submission Open

Keywords: crystal engineering; multicomponent crystals; cocrystal; nanococrystal; controllable synthesis; poorly soluble active ingredient; solubilization; bioavailability; pharmaceutical; nutraceutical; co-delivery; combination product

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Biomaterials-Based Drug Delivery Systems in Regenerative Medicine

edited by

Rogério Leone Buchaim

submission deadline 31 Aug 2026 | Viewed by 545 | Submission Open

Keywords: tissue regeneration; drug delivery systems; regenerative medicine; biomaterials; stem cell therapy; gene therapy; nanostructured biomaterials; biomimetic materials; decellularized extracellular matrices

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Emerging Trends in Nanocarriers for Therapeutic and Diagnostic Purposes

edited by

Raquel Silva Araújo

Vanessa Carla Furtado Mosqueira

and Maria Alice de Oliveira

submission deadline 31 Aug 2026 | Viewed by 460 | Submission Open

Keywords: production process; characterization methods; surface modification; smart biodegradable polymers; biodistribution; efficacy studies; diagnostic; theranostic; PET/SPECT/MR imaging; radiolabeled nanoparticles; drying technologies; scale-up technologies; targeted therapy

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Application of Electrohydrodynamic Techniques for Delivery of Therapeutic Agents

edited by

Gustavo Abraham

and

Silvestre Manuel Bongiovanni Abel

submission deadline 10 Sep 2026 | 2 articles | Viewed by 2753 | Submission Open

Keywords: drug-loaded electrospun nanofibrous mats; drug-loaded electrosprayed micro- and nanoparticles; targeted drug delivery systems; therapeutic agent’ s encapsulation techniques; antimicrobial nanofibrous mats; protein-loaded release; novel applications of electrospun nanofibers

(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)

Pharmacy Compounding of Personalized Preparation for Specific Patients: Challenges and Advantages, 2nd Edition

edited by

and

submission deadline 10 Sep 2026 | 1 articles | Viewed by 1519 | Submission Open

Keywords: formulations; drug compounding; extemporaneous preparations; galenics; quality; standard operating procedures

(This special issue belongs to the Section Physical Pharmacy and Formulation)

Carbohydrate-Based Carriers for Drug Delivery, 2nd Edition

edited by

Ioana Mirela Vasincu

and

Lenuta Profire

submission deadline 18 Sep 2026 | 3 articles | Viewed by 5583 | Submission Open

Keywords: nanomaterials; drug delivery; release profile; polisaccharides; oligosaccharides; inclusion complexes; targeted therapy

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Challenges and Future Trends of Nano-Based Drug Delivery System in the Treatment of Bone Diseases

edited by Xiao Lin and Jie Shang

submission deadline 25 Sep 2026 | 4 articles | Viewed by 9076 | Submission Open

Keywords: nano-based drug delivery system; drug delivery particles; controlled release; stimuli-responsive drug delivery system; photodynamics therapy; nanozymes; organic porous materials; osteoporosis; fracture healing; osteoarthritis; bone tissue regeneration

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Proteases and Serpins: Therapeutic Targets for Various Diseases

edited by

Crispin R. Dass

submission deadline 30 Sep 2026 | 5 articles | Viewed by 12636 | Submission Open

Keywords: serpin; protease; serine protease inhibitors; disease; cancer; diabetes; cardiovascular disease; inflammatory disease; therapy; drug development; oxidative stress

(This special issue belongs to the Section Drug Targeting and Design)

Innovative Drug Delivery Strategies for Targeted Cancer Immunotherapy

edited by Jingjing Sun

submission deadline 30 Sep 2026 | 4 articles | Viewed by 8655 | Submission Open

Keywords: immunomodulatory agents; cancer immunotherapy; drug delivery; nanoparticles; checkpoint inhibitors; nanocarriers

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Optimizing Drug Therapy Through Pharmacokinetics and Therapeutic Drug Monitoring

edited by Kazuro Ikawa and

Tetsushu Onita

submission deadline 30 Sep 2026 | Viewed by 127 | Submission Open

Keywords: dosing optimization; therapeutic drug monitoring; pharmacokinetics; pharmacodynamics; modeling and simulation; special population

(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)

Nanoadjuvants for Drug Delivery and Immunotherapy

edited by

Lingxiao Zhang

and

Maoze Wang

submission deadline 30 Sep 2026 | Viewed by 82 | Submission Open

Keywords: adjuvants; nanoadjuvants; nano-aluminum adjuvants; nanoparticles; vaccines; immunotherapy; drug delivery system; clinical translation; biosafety

(This special issue belongs to the Section Nanomedicine and Nanotechnology)

Recent Advances in Drug Delivery Through Microneedle-Based Systems

edited by

Antonio José Guillot

submission deadline 31 Oct 2026 | Viewed by 60 | Submission Open

Keywords: microneedle-based systems; microneedles; micro array patches; skin delivery; transdermal delivery; vaccination

(This special issue belongs to the Section Drug Delivery and Controlled Release)

Recent Advances in Pharmaceutical Formulation

edited by Magdalena Bîrsan,