Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Block Co-Polymer Nanomedicines: Innovations in Effective Drug Delivery submission deadline 30 Nov 2025 | Viewed by 200 | Submission Open
Keywords: pluronic-based nanomedicines and hydrogels; gene delivery; advanced drug delivery systems; radiotherapy and photodynamic therapy; combination therapy; polymeric nanomedicines; immunotherapy; nanogels; small-molecule delivery systems; block co-polymers nanomedicines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
A New Generation of Metal Anticancer Drugs
edited by
submission deadline 30 Nov 2025 | Viewed by 153 | Submission Open
Keywords: metal-based drugs; cytotoxicity; cancer; nanoparticles; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biocompatible Polymer-Based Nanocarriers and Nanocomposites as Drug Delivery Systems
edited by
submission deadline 30 Nov 2025 | Viewed by 112 | Submission Open
Keywords: biocompatible nanocomposites; polymer-based nanocomposites; drug delivery; controlled-release systems; nanocarriers; nanomedicine; nanocomposite toxicity; vaccines; gene delivery; cancer therapy; neurodegenerative diseases
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Vaccine Delivery and Vaccine Administration submission deadline 30 Nov 2025 | Viewed by 107 | Submission Open
Keywords: vaccine delivery; vaccination; vaccine immunity; humoral immune response; cell-mediated immunity; infectious diseases; vaccine administration; novel routes of vaccination; nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Drug Delivery Systems for Natural Products submission deadline 30 Nov 2025 | Viewed by 94 | Submission Open
Keywords: natural products; advanced drug delivery systems; liposomes; niosomes; phytosomes; lipid nanoparticles; smart polymers; biodegradable nanoparticles; polymeric nanoparticles; drug carriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Formulation, Characterization, and Performance Testing of Topical Semisolid Products
edited by and Seeprarani Rath
submission deadline 30 Nov 2025 | Viewed by 93 | Submission Open
Keywords: formulation of topical semisolid dosage forms; characterization of topical semisolid dosage forms; microstructure; in vitro release and permeation testing; bioavailability and bioequivalence; topical and transdermal delivery; quality-by-design
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biomaterials for Skin Drug Delivery
edited by
submission deadline 30 Nov 2025 | Viewed by 89 | Submission Open
Keywords: skin drug delivery; transdermal delivery; topical delivery; skin permeation; biomaterials; hydrogels; microneedles; nanocarriers; bioresponsive materials
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Manipulation of the Blood–Brain Barrier for CNS Drug Delivery Enhancement
edited by David Fortin and
submission deadline 30 Nov 2025 | Viewed by 84 | Submission Open
Keywords: blood– brain barrier (BBB); intra-arterial infusion; BBB manipulation; efflux transporters; CNS delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Physiologically Based Biopharmaceutics Modeling
edited by Atsushi Kambayashi
submission deadline 30 Nov 2025 | Viewed by 78 | Submission Open
Keywords: oral drug absorption; bioavailability; bioequivalence; modeling and simulation; physiologically based biopharmaceutics modeling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Natural Compounds in Drug Delivery Systems submission deadline 30 Nov 2025 | Viewed by 72 | Submission Open
Keywords: natural products; extraction techniques; phytochemical analyses; natural compounds; biological active compounds; new formulations; encapsulated technics; biotechnology; drug delivery systems; bioavailability; pharmacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Next-Generation Non-Viral Vectors for Gene Therapy and DNA Vaccination
edited by
submission deadline 30 Nov 2025 | Viewed by 71 | Submission Open
Keywords: non-viral vectors; gene therapy; DNA vectors; plasmid vectors; mRNA vectors; lipid nanoparticles (LNPs); cell-free DNA synthesis; gene electrotransfer; targeted gene delivery; non-viral vector manufacturing; clinical translation of gene therapies
(This special issue belongs to the Section Gene and Cell Therapy)
Innovative Therapies for Neurodegenerative Diseases submission deadline 30 Nov 2025 | Viewed by 67 | Submission Open
Keywords: nanotechnology-based therapies; cellular and regenerative therapies; stem cell therapy; gene therapy and RNA interference; protein aggregation inhibitors; neuroinflammation modulators; mitochondrial dysfunction-targeted drugs; preclinical and clinical trials
(This special issue belongs to the Section Gene and Cell Therapy)
The Preparation of an Exosome/Liposomal Nano-Drug Delivery System and Its Application in the Treatment of Inflammatory Bowel Disease
edited by and
submission deadline 30 Nov 2025 | Viewed by 66 | Submission Open
Keywords: exosomes; liposomes; nano-drug delivery systems; inflammatory bowel disease (IBD); targeted therapy; mucosal drug delivery; drug encapsulation; immunomodulation; nanomedicine; extracellular vesicles; personalized medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Therapeutic Agents and Innovative Delivery Systems Against Infectious Diseases
edited by Sara Consalvi
submission deadline 30 Nov 2025 | Viewed by 59 | Submission Open
Keywords: medicinal chemistry; antibacterials; antivirals; antimicrobials; drug resistance; drug delivery; drug candidate; drug repurposing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovations in Advanced Drug Delivery Systems: Overcoming Challenges for Personalized Medicine
edited by Hélcio Silva Dos Santos
submission deadline 30 Nov 2025 | Viewed by 53 | Submission Open
Keywords: drug administration; polymers; structural characterization; nanoparticles; in silico studies; toxicity; bioavailability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Formulation of Lipid-Based Nanocapsules: Drug Release, Permeability, Biocompatibility, and Stability Studies
edited by and Carolina Arrúa
submission deadline 30 Nov 2025 | Viewed by 52 | Submission Open
Keywords: drug delivery; lipid nanocapsules; permeability; biocompatibility; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Engineering and Characterisation of Novel Nanomedicine Formulations, 3rd Edition
edited by and Raquel Fernández García
submission deadline 30 Nov 2025 | Viewed by 47 | Submission Open
Keywords: nanoparticles; liposomes; solid lipid nanocapsules; drug targeting; cancer; infectious diseases; nanovaccines
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Therapeutic Drug Monitoring as a Useful Tool in Therapy Improvement, 3rd Edition submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open
Keywords: drug– drug interactions; pharmacokinetics; therapeutic drug monitoring; machine learning
(This special issue belongs to the Section Clinical Pharmaceutics)
Model-Based Formulation Strategies for Controlled Release of Active Ingredients
edited by , Patrick D. Sinko and
submission deadline 30 Nov 2025 | Viewed by 39 | Submission Open
Keywords: in vitro and in vivo correlation; simultaneous dissolution– absorption evaluation; controlled release; sustained release; drug delivery systems; nanoparticles; micelles; liposomes; nanomaterials; amorphous solid dispersions; molecular dynamics simulations; computational fluid dynamics; computationally designed proteins; computationally designed peptides; pharmacokinetic model; pharmacometric model; 3D printing (personalized medicines/materials development/printing technologies)
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Nanosystems for Advanced Diagnostics and Therapy submission deadline 30 Nov 2025 | Viewed by 30 | Submission Open
Keywords: nanosystems; theranostics; nanomedicine; molecular imaging; targeted drug delivery; radiolabeled nanoparticles; image guided therapy; smart nanocarriers; nanoradiopharmaceuticals; nanotechnology in diagnostics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Anti-Inflammatory Effects from Natural Bioactive Compounds—from Bench to Bedside, 3rd Edition
edited by
submission deadline 30 Nov 2025 | Viewed by 20 | Submission Open
Keywords: inflammation; bioproducts; isolated compounds; cytokines; macrophages; autoimmune diseases; in vivo assay; in vitro assay
(This special issue belongs to the Section Drug Targeting and Design)
The Exciting Opportunities That Radiopharmaceuticals Have to Offer: Nuclear Medicine Imaging, Therapy and Drug Delivery Systems
edited by Yanli Wang and
submission deadline 30 Nov 2025 | Viewed by 19 | Submission Open
Keywords: PET imaging; theranostics; molecular imaging probes; radionuclide therapy; neuroimaging; radiochemistry
(This special issue belongs to the Section Drug Targeting and Design)
Smart Radiotherapy Biomaterials for Cancer Therapy and Imaging submission deadline 10 Dec 2025 | Viewed by 385 | Submission Open
Keywords: multifunctional biomaterials; theranostic biomaterials; smart drug delivery systems; nanobiomaterials; cancer radiotherapy; polymer-based biomaterials nanocarriers customizable biomaterials for cancer therapy and imaging smart nanomaterials
(This special issue belongs to the Section Drug Targeting and Design)
Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
edited by Robertas Lazauskas, Dalia Adukauskienė, and Inga Staneviciene
submission deadline 10 Dec 2025 | Viewed by 40 | Submission Open
Keywords: chitosan-based nanoparticles; oxidative stress; targeted drug delivery; biopharmaceutical applications; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
PLGA Implants for Controlled Drug Release
edited by Emma Portnoy
submission deadline 10 Dec 2025 | Viewed by 11 | Submission Open
Keywords: nanoparticles; drug delivery; liposomes; lipid nanoparticles; PLGA nanoparticles; PLA nanoparticles
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Therapeutic Approaches for the Application of Natural Products in Skin Diseases submission deadline 11 Dec 2025 | Viewed by 147 | Submission Open
(This special issue belongs to the Section Biopharmaceutics)
Natural Products with Antimicrobial Activity and Their Pharmaceutical Delivery Systems submission deadline 15 Dec 2025 | Viewed by 504 | Submission Open
Keywords: antibacterial; antiparasitic; antifungal; antiviral; natural compounds; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancements in Pro-Regenerative Hydrogel Scaffolds for Tissue Engineering and Regenerative Medicine
edited by and Dubravka P. Živanović
submission deadline 20 Dec 2025 | 2 articles | Viewed by 3492 | Submission Open
Keywords: pro-regenerative scaffolds for tissue engineering; ECM-like hydrogel substitutes; scaffolds for wound healing; scaffolds for bone and cartilage regeneration; scaffolds for nerve reparation; bioactive 3D scaffolds; scaffolds for engineering of 3D tumor tissue; multi-biofunctional scaffolds for tissue regeneration
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Chitosan-Based Nanoparticles for Drug Delivery
edited by Delia Mihaela Raţă
submission deadline 20 Dec 2025 | 2 articles | Viewed by 2326 | Submission Open
Keywords: nanoparticles; drug delivery systems; chitosan-coated liposomes; solid lipid nanoparticles; chitosan nanofibers; conjugated polymers; nanocomposites
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Phytocompounds-Based Formulations for Anti-Inflammatory Disorders
edited by Gustavo Costa
submission deadline 20 Dec 2025 | 1 articles | Viewed by 1076 | Submission Open
Keywords: phytocompounds; natural compounds; phytotherapy; plant-based drugs; anti-inflammatory; pharmaceutical forms
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Amorphous Solid Dispersions
edited by
submission deadline 20 Dec 2025 | Viewed by 199 | Submission Open
Keywords: amorphous solid dispersions; solubility enhancement; bioavailability; hot melt extrusion; ball milling; spray drying; freeze-drying; drug– polymer interactions; stability; pharmaceutical formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Nano-Formulations for Drug Delivery and Cancer Immunotherapy
edited by
submission deadline 20 Dec 2025 | Viewed by 103 | Submission Open
Keywords: nanomedicine; drug delivery systems; cancer immunotherapy; targeted therapy; nanoparticle design; tumor microenvironment; immune checkpoint blockade; combination therapy; stimuli-responsive carriers; clinical translation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Microparticle-Based Drug Delivery Systems submission deadline 20 Dec 2025 | Viewed by 83 | Submission Open
Keywords: drug delivery systems; microparticles; biodegradable polymers; bioactive compounds; biomedical applications; biocompatibility; biological properties
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biocompatible Liposomes for Drug Delivery: Materials and Applications
edited by , , Rajendran C. Gopalan and
submission deadline 20 Dec 2025 | Viewed by 66 | Submission Open
Keywords: inhalation; liposome; prodrug; nanomedicine (lipid carriers for drug delivery); biocompatible liposomes
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Ocular Drug Delivery Systems and Formulations submission deadline 20 Dec 2025 | Viewed by 62 | Submission Open
Keywords: ocular drug delivery; ophthalmic formulations; ophthalmic drug bioavailability; ophthalmic hydrogels; ophthalmic pharmaceutical nanotechnology; ocular therapies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Cyclodextrin-Modified Nanomaterials for Drug Delivery and Biomedical Applications: Theoretical and Experimental Studies submission deadline 20 Dec 2025 | Viewed by 33 | Submission Open
Keywords: cyclodextrin-based nanoparticles and nanomaterials; modified cyclodextrins and pharmaceutical uses; drug release systems; biomaterials; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Drug Polymorphism and Dosage Form Design, 2nd Edition
edited by Rubén M. Maggio and
submission deadline 26 Dec 2025 | 1 articles | Viewed by 1762 | Submission Open
Keywords: polymorphism; solid state; dissolution; dosage form design; stability; mechanical properties; vibrational spectroscopy; quality by design; process analytical technologies; active pharmaceutical ingredient
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Transdermal Delivery of Low-Molecular-Weight Drugs and New Modality of Drugs: Recent Innovation to Penetration Enhancement Techniques
edited by and Takeshi Oshizaka
submission deadline 30 Dec 2025 | 3 articles | Viewed by 4007 | Submission Open
Keywords: transdermal delivery; enhanced skin permeation; penetration enhancer; microneedle; iontophoresis; new modality; easy administration; skin barrier
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology in Antibacterial Drug Delivery submission deadline 30 Dec 2025 | 1 articles | Viewed by 794 | Submission Open
Keywords: multidrug resistance; antibiotic resistance; multidrug-resistant bacteria; antibiotics; antibacterial therapies; nanotechnology; antibacterial drug delivery; nanoparticles; targeted delivery; controlled release
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
New Trends in the Controlled Release Systems of Medicinal Substances Used in the Treatment of Diseases of the Central Nervous System
edited by and
submission deadline 31 Dec 2025 | 3 articles | Viewed by 19726 | Submission Open
Keywords: drug delivery systems; brain-targeting drug delivery; central nervous system; schizophrenia; depression; Parkinson’ s disease; Alzheimer’ s disease; glioblastoma multiforme
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Novel Micro/Nanomaterials Based Drug Delivery Systems for Theranostic Applications submission deadline 31 Dec 2025 | 6 articles | Viewed by 10825 | Submission Open
Keywords: nanotechnology; drug delivery systems; theranostics; micro/nanomaterials; personalized medicine; nanomedicine; cancer; diagnosis
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Application Prospects of Hydrogels in Drug Delivery Systems submission deadline 31 Dec 2025 | 2 articles | Viewed by 5716 | Submission Open
Keywords: hydrogels; osteochondral defects; drug-delivery systems; cell-laden hydrogels; nanoparticle-loaded hydrogels
(This special issue belongs to the Section Drug Targeting and Design)
Development of New Nanotechnological Systems Loaded with Drugs for Infectious Disease Application
edited by , Marlus Chorilli and Taís Maria Bauab
submission deadline 31 Dec 2025 | 4 articles | Viewed by 5304 | Submission Open
Keywords: nanosystems; controlled drug release; infectious diseases; microbial resistance; pathogenic microorganism; drug delivery systems; nanotechnology; nanotherapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Cutting-Edge Drug Delivery and Nanomedicine: Innovations in Hybrid Systems, Theranostics and Targeted Therapies submission deadline 31 Dec 2025 | 4 articles | Viewed by 4063 | Submission Open
Keywords: drug delivery; nanomedicine; hybrid nanosystems; targeted therapies; theragnostic; drug repurposing; PDT; PTT
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Dermal and Transdermal Drug Delivery Systems submission deadline 31 Dec 2025 | 2 articles | Viewed by 4056 | Submission Open
Keywords: transdermal drug delivery; dermal drug delivery; nanotechnology; biopatch; nanocarriers; microneedles; skin penetration; electroporation; iontophoresis
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Stem Cell Therapy and Nanodelivery Systems for Tissue Engineering
edited by
submission deadline 31 Dec 2025 | 1 articles | Viewed by 3301 | Submission Open
Keywords: biomaterials; multipotent stem cells; tissue regeneration; adult stem cells; induced pluripotent stem cells; cell engineering; tissue engineering; organoid
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Recent Advances in Inhibitors for Targeted Therapies
edited by Anke Wilhelm
submission deadline 31 Dec 2025 | 4 articles | Viewed by 2989 | Submission Open
Keywords: targeted therapy; emerging technologies; antiviral strategies; inhibitor development; molecular targets; precision medicine; drug R& D dynamics; pharmaceutics; drug resistance
(This special issue belongs to the Section Drug Targeting and Design)
Exploring the Versatility of Cyclodextrins in Pharmaceutical Formulations submission deadline 31 Dec 2025 | 1 articles | Viewed by 2269 | Submission Open
Keywords: cyclodextrins; CDs; inclusion complexes; cyclodextrin-based nanosponges; excipients; host– guest complexes; complexes
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Application of Marine-Derived Polymers in Drug Dosage Forms submission deadline 31 Dec 2025 | 2 articles | Viewed by 2047 | Submission Open
Keywords: pharmaceutical formulations; controlled drug release; biological activity of drug fromulations; marine-derived polymers; alginates; chitosan; fucoidan
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Physiologically Based Pharmacokinetics
edited by Li Liu
submission deadline 31 Dec 2025 | 1 articles | Viewed by 1531 | Submission Open
Keywords: physiologically based pharmacokinetic (PBPK) model; pharmacometrics; drug– drug interaction; pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
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