Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Surfactants and Amphiphiles as Key Components in Diverse Pharmaceutical and Biomedical Applications submission deadline 30 Nov 2026 | Viewed by 207 | Submission Open
Keywords: amphiphile design; structure–function relationships; self-assembly; nanomedicine; drug delivery; supramolecular chemistry; pharmaceutical applications
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Next-Generation Strategies for Photodynamic Therapy: Advanced Delivery Systems and Therapeutic Optimization
edited by and Natalia Belén Rumie Vittar
submission deadline 30 Nov 2026 | Viewed by 186 | Submission Open
Keywords: photodynamic therapy; photosensitizers; nanotechnology; liposomes; therapeutic resistance; novel cell targets; cancer therapy optimization; combinational therapies; biomaterials; targeted therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Mechanism-Based Pharmacokinetic and Pharmacodynamic Modeling, 2nd Edition
edited by
submission deadline 30 Nov 2026 | Viewed by 185 | Submission Open
Keywords: PK/PD modeling; disease progression modeling; quantitative system pharmacology; physiologically based modeling
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Advancing Biologic Drug Development Through Physiologically Based Pharmacokinetic Modeling and Simulations, 2nd Edition
edited by and Javier Reig Lopez
submission deadline 30 Nov 2026 | Viewed by 170 | Submission Open
Keywords: monoclonal antibodies; antibody–drug conjugates; bispecific antibodies; PBPK; target-mediated drug disposition; lysosomal degradation; FcRn binding; special populations
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Metal Complexes for Anticancer and Antibacterial Drug Delivery
edited by Despoina Varna and Rigini M. Papi
submission deadline 30 Nov 2026 | Viewed by 164 | Submission Open
Keywords: bioactive metal complexes; anticancer; antibacterial; drug delivery; targeted treatment
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Insights on Gold Nanoparticle Applications in Medicine
edited by Veronika Malyško and
submission deadline 30 Nov 2026 | Viewed by 124 | Submission Open
Keywords: gold nanoparticles; AuNPS; drug delivery; nanocarriers; controlled drug release; drug targeting; nanocarriers; gene delivery; electroporation; surface modification; toxicity
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Polymeric Materials and Drug Delivery Systems for Dental and Oral Health Applications submission deadline 10 Dec 2026 | 3 articles | Viewed by 7226 | Submission Open
Keywords: prevention; dentistry; regeneration; drug delivery systems; antimicrobial properties; topical delivery; cancer therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Therapeutic Advances in Chronic Diseases: Innovation and Drug Repurposing submission deadline 10 Dec 2026 | 2 articles | Viewed by 3379 | Submission Open
Keywords: chronic diseases; drug repurposing; therapeutic target discovery; drug delivery systems; drug reformulation; combination therapy; nanomedicine; pharmacokinetics; controlled release; translational pharmaceutics
(This special issue belongs to the Section Biologics and Biosimilars)
Probiotics in Pharmaceutics: Exploring the Therapeutic Potential and Formulation Strategies submission deadline 18 Dec 2026 | 4 articles | Viewed by 5829 | Submission Open
Keywords: probiotics; formulation; drug delivery; therapeutic potential; microbiome modulation; nutraceuticals; immunomodulation; clinical trials; regulatory affairs
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in the Development, Characterization, and Stability Aspects of RNA-Based Vaccines
edited by and
submission deadline 20 Dec 2026 | 5 articles | Viewed by 17062 | Submission Open
Keywords: RNA-based vaccines; lyophilization; stability; gene therapy; formulation strategies; novel characterization; delivery systems; biopharmaceuticals; continuous manufacturing; AI/ML/digital twin
(This special issue belongs to the Section Gene and Cell Therapy)
Design of Dosage Forms to Enhance Biopharmaceutical Properties submission deadline 20 Dec 2026 | 2 articles | Viewed by 3880 | Submission Open
Keywords: biopharmaceutics; drug delivery; prodrug; amorphous dispersion; self-emulsifying dispersion; cyclodextrins; nanocrystals; modified release; peptide; antibody
(This special issue belongs to the Section Biopharmaceutics)
Advances in Drug Delivery Systems for the Management of Metabolic Diseases submission deadline 31 Dec 2026 | 4 articles | Viewed by 10197 | Submission Open
Keywords: drug delivery systems; metabolic diseases; nanotechnology; synthetic drugs and natural extracts; preclinical and clinical studies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing Cancer Therapy: Magnetic Nanoparticles for Enhanced Targeted Drug Delivery submission deadline 31 Dec 2026 | 2 articles | Viewed by 8140 | Submission Open
Keywords: cancer therapy; drug delivery; magnetic drug targeting; superparamagnetism; hyperthermia; magnetite; ferrite; iron oxide magnetic nanoparticles; superparamagnetic iron oxide nanoparticles; cytotoxicity; apoptosis; magnetic biosensors; magnetic imaging; theranostics
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanoparticle-Based Gene Delivery
edited by Xiubo Zhao and
submission deadline 31 Dec 2026 | 3 articles | Viewed by 7926 | Submission Open
Keywords: nanaoparticles; gene delivery; nucleic acids; DNA; RNA; gene therapy
(This special issue belongs to the Section Gene and Cell Therapy)
In Silico Pharmacokinetic and Pharmacodynamic (PK-PD) Modeling submission deadline 31 Dec 2026 | 3 articles | Viewed by 7313 | Submission Open
Keywords: physiologically based pharmacokinetics (PBPKs); population pharmacokinetics (PopPKs); quantitative systems pharmacology (QSP); Bayesian modeling; artificial intelligence in PK-PD; in silico bioequivalence; multi-objective optimization; translational pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Microfluidics-Driven Formulations: Exploring Liposomes and Emulsions for Drug Delivery
edited by Naresh Yandrapalli and
submission deadline 31 Dec 2026 | 3 articles | Viewed by 6222 | Submission Open
Keywords: microfluidics; drug delivery systems; liposomes; emulsions; synthetic cells; personalized medicine; multi-drug therapy; scalable manufacturing; micro-/nano-carriers; material science; pharmaceutical innovation; engineering solutions
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advances in Pharmaceutical Cocrystal Design and Technological Applications submission deadline 31 Dec 2026 | 2 articles | Viewed by 4920 | Submission Open
Keywords: pharmaceutical cocrystal; cocrystal design and formation; advanced drug delivery systems; transdermal and microneedle applications; inhalable formulations; 3D printing of pharmaceuticals; nanotechnology in drug delivery; stability and characterization of cocrystals; regulatory aspects of cocrystal-based formulation
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Biomaterials for Oral and Dental Drug Delivery submission deadline 31 Dec 2026 | 3 articles | Viewed by 4224 | Submission Open
Keywords: oral drug delivery; dental drug delivery; biomaterials; mucoadhesive systems; tissue regeneration; periodontal therapy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Pharmaceutical Formulation
edited by Magdalena Bîrsan, and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 4214 | Submission Open
Keywords: sustainable excipients; preformulated bases; drug delivery platforms; pharmaceutical formulation; personalized therapies
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Innovative Viral and Non-Viral Vectors for Drug Delivery, Vaccine Development, Therapeutic Applications and Diagnosis submission deadline 31 Dec 2026 | 3 articles | Viewed by 3506 | Submission Open
Keywords: viral vector engineering; non-viral delivery systems; vaccine development; infection management; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Extemporaneous Formulations: Filling the Gap in the Pharmaceutical Industry with Personalized Medicines, 2nd Edition submission deadline 31 Dec 2026 | 2 articles | Viewed by 3410 | Submission Open
Keywords: extemporaneous; compounding; pharmaceutical; formulation; personalized; pharmacy
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Ultrasound‑Enhanced Drug Delivery: Applications and Therapeutic Advances submission deadline 31 Dec 2026 | 2 articles | Viewed by 3132 | Submission Open
Keywords: therapeutic ultrasound; high‑intensity focused ultrasound (HIFU); focused ultrasound surgery (FUS); histotripsy; sonoporation; sonodynamic therapy; drug delivery; microbubbles; nanoparticles; cancer; neurodegenerative conditions
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanocarriers in Cardiovascular Medicine: Current Applications and Future Perspectives
edited by and Francislaine Aparecida Dos Reis Lívero
submission deadline 31 Dec 2026 | 1 articles | Viewed by 2836 | Submission Open
Keywords: drug delivery; biopharmaceutical; quality control; nanocarriers; nanoparticle; cardioprotection; hypertension; drug development; arteriosclerosis; thrombosis
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Polymer Systems for Drug-Delivery Applications submission deadline 31 Dec 2026 | 3 articles | Viewed by 2770 | Submission Open
Keywords: polymer-based drug delivery; controlled release; drug encapsulation; drug delivery vehicles; sustained release systems; biodegradable polymers; polymeric nanoparticles; nanoparticle surface modification; targeted drug delivery; tissue-specific delivery; stimuli-responsive polymers; pH-sensitive polymers; thermoresponsive polymers; enzyme-responsive polymers; nanocarriers; polymeric micelles; polymeric hydrogels; polymeric nanocomposites; polymersomes; polymer-drug conjugates
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biocompatible Liposomes for Drug Delivery: Materials and Applications
edited by , , Rajendran C. Gopalan and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2686 | Submission Open
Keywords: inhalation; liposome; prodrug; nanomedicine (lipid carriers for drug delivery); biocompatible liposomes
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanocarriers and Delivery Systems for Next-Generation Nanomedicine Therapies
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2623 | Submission Open
Keywords: nanocarriers; targeted delivery systems; stimuli-responsive materials; co-delivery systems; theranostic nanoplatforms; clinical translation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Personalized Medicine: Integrating Pharmacogenetics and Pharmacokinetics submission deadline 31 Dec 2026 | 1 articles | Viewed by 2446 | Submission Open
Keywords: personalized medicine; pharmacogenetics; pharmacokinetics; drug metabolism; genetic variations; therapeutic response; drug dosage optimization
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Biodegradable Polymer Platforms for Long-Acting Drug Delivery
edited by and Archana Krovi
submission deadline 31 Dec 2026 | 1 articles | Viewed by 2382 | Submission Open
Keywords: sustained release systems; long-acting drug delivery; controlled drug delivery; biodegradable polymers; long-acting injectables; injectable depots; nanoparticles and microparticles; long-acting implants; polymer–drug conjugates; parenteral formulations
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Studies of Protein–Ligand Interactions in the Evaluation of the Biological Activity of Compounds submission deadline 31 Dec 2026 | 2 articles | Viewed by 2149 | Submission Open
Keywords: protein-ligand interactions; ADMET properties; biological activity; toxicity; molecular docking; dynamic simulations; enzymes inhibition; drug-receptor binding
(This special issue belongs to the Section Biopharmaceutics)
Bioavailability and Bioequivalence Assessment of Topical Drug Products Intended for Local Action
edited by and Seeprarani Rath
submission deadline 31 Dec 2026 | 1 articles | Viewed by 2082 | Submission Open
Keywords: bioequivalence; bioavailability; biowaivers; topical dosage forms for local action; topical corticosteroids; dermatopharmacokinetics; in vitro release tests (IVRTs)/in vitro permeation tests (IVPTs); pharmaceutical equivalence; semi-solid dosage forms; human skin; vasoconstrictor assay (VCA) in place of human skin
(This special issue belongs to the Section Biopharmaceutics)
Challenges and Trends in Geriatric Pharmacotherapy: Pharmacodynamics, Pharmacokinetics, and Personalized Therapeutic Strategies submission deadline 31 Dec 2026 | 1 articles | Viewed by 1978 | Submission Open
Keywords: pharmacokinetics; pharmacodynamics; drug–drug interactions; drug monitoring; precision dosing; therapeutic strategies; individualized therapy; personalized medicine
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Innovative Drug Delivery Strategies Across Biological Barriers: From Organ-on-a-Chip Models to Nanopharmaceuticals submission deadline 31 Dec 2026 | 1 articles | Viewed by 1775 | Submission Open
Keywords: drug delivery systems; biological barriers; blood–brain barrier (BBB); organ-on-a-chip; lab-on-a-chip; nanopharmaceuticals; 3D printing in pharmaceutics; targeted delivery; transdermal delivery; nasal drug delivery; ocular drug delivery; pulmonary delivery; gene therapy; nanocarriers; personalized medicine; bioavailability enhancement; transporter-mediated drug delivery; in vitro models; barrier modeling; patient-centric formulations
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders
edited by and Chiara Lucchi
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1629 | Submission Open
Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection
(This special issue belongs to the Section Gene and Cell Therapy)
Oligonucleotide Aptamers for Diagnostics and Therapy submission deadline 31 Dec 2026 | 1 articles | Viewed by 1593 | Submission Open
Keywords: aptamers; oligonucleotides; therapy; diagnostics; targeted drug delivery; molecular recognition; aptamer engineering; protein–aptamer interactions; aptamer-based nanotechnology
(This special issue belongs to the Section Gene and Cell Therapy)
Clinical Pharmacokinetics and Pharmacodynamics of Antimicrobial Therapy
edited by , , José Germán Sánchez-Hernández and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1110 | Submission Open
Keywords: antimicrobial; antibacterial; antibiotics; antifungal; pharmacokinetics; pharmacodynamics; PK/PD; MIPD; drug monitoring; TDM; gentamicin; vancomycin; meropenem; daptomycin
(This special issue belongs to the Section Clinical Pharmaceutics)
Smart Hydrogels for Drug Delivery Systems and Precision Medicine
edited by Teresa Del Castillo-Castro, and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 1079 | Submission Open
Keywords: hydrogel; 3D/4D bioprinting; natural polymer; self-assembling hydrogels; nanocomposite hydrogels; drug delivery; tissue regeneration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Drug Delivery and Therapeutic Strategies for Chronic Diseases and Pain
edited by and
submission deadline 31 Dec 2026 | 1 articles | Viewed by 892 | Submission Open
Keywords: biologics; protein engineering; molecular pharmacology; gene therapy; functional coating; chronic pain; diabetes; inflammation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Novel Strategies for Enhancing Oral Bioavailability submission deadline 31 Dec 2026 | 1 articles | Viewed by 625 | Submission Open
Keywords: oral; formulation; delivery system; chemical modification; pro-drug; analogue
(This special issue belongs to the Section Biopharmaceutics)
Overcoming Biological Barriers: Novel Strategies in Drug Delivery submission deadline 31 Dec 2026 | Viewed by 566 | Submission Open
Keywords: biological barriers; drug delivery systems; permeability
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Micro- and Nanoemulsion-Based Systems for Controlled and Targeted Drug Delivery submission deadline 31 Dec 2026 | Viewed by 526 | Submission Open
Keywords: nanoemulsion; microemulsion; SNEDDS; quality by design (QbD); surfactants; functionalization; drug release; emulsion stability; droplet size control; interfacial properties
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Model Informed Precision Dosing in Special Populations: Bridging Physiology, Models and Clinical Practice
edited by
submission deadline 31 Dec 2026 | Viewed by 523 | Submission Open
Keywords: PBPK; PopPK; pregnancy; neonates; pediatrics; geriatrics; dosing; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Nanotechnology for the Prevention, Diagnosis, and Therapy of HIV, HCV, and Coinfection: From Bench to Bedside submission deadline 31 Dec 2026 | Viewed by 515 | Submission Open
Keywords: dendrimers; diagnostics; drug resistance; HCV; HIV; HIV/HCV coinfection; liposomes; nanocarriers; nanoparticles; nanoplatforms; nanotechnology; prevention; targeted drug delivery; therapeutic
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology and Cell Therapies for Ocular Diseases
edited by and
submission deadline 31 Dec 2026 | Viewed by 494 | Submission Open
Keywords: nanotechnology; limbal stem cells; cell cultivation techniques; eye barriers; drug delivery systems; retinal degenerations
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Gold Nanoparticles in Cancer Photothermal Therapy: Current Trends and Future Directions submission deadline 31 Dec 2026 | Viewed by 471 | Submission Open
Keywords: photothermal therapy; gold nanoparticles; optimization; numerical/analytical analysis; in vitro/in vivo Experiments; treatment effect
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Dendrimer-Mediated Drug, Gene, and Protein Delivery for Disease Treatment submission deadline 31 Dec 2026 | Viewed by 468 | Submission Open
Keywords: dendrimers; drug delivery; gene delivery; protein delivery; targeted therapy; bioconjugation; controlled release; tumor therapy; inflammatory diseases; infectious diseases
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Shape Memory Polymers for Drug Delivery and Tissue Engineering
edited by
submission deadline 31 Dec 2026 | Viewed by 411 | Submission Open
Keywords: shape memory polymers; smart biomaterials; drug delivery system; tissue engineering; regenerative medicine; controlled release; biomedical applications; electrospinning; 3D printing; microfluidic
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Bridging Computational and Experimental Methods in the Assessment of Novel Drug Formulations submission deadline 31 Dec 2026 | Viewed by 363 | Submission Open
Keywords: molecular modeling; in silico–in vitro correlation (IVIVC); drug delivery systems; pharmacokinetic modeling; computational pharmaceutics
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Innovations in Nanomedicine and Polymeric Drug Delivery submission deadline 31 Dec 2026 | Viewed by 345 | Submission Open
Keywords: nanomedicine; polymeric drug delivery; lipid-based carriers; targeted delivery; gene delivery; controlled release; nano–bio interface; stimuli-responsive systems; pharmacokinetics; computational modeling
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology and Pharmaceutical Innovations in Oral Diseases
edited by and Kristen E. Bremmell
submission deadline 31 Dec 2026 | Viewed by 324 | Submission Open
Keywords: nanotechnology; oral drug delivery; nanocarriers; mucoadhesive systems; controlled release; bioavailability enhancement; periodontal therapy; oral cancer therapeutics; regenerative dentistry; antimicrobial nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Development of New Nanotechnological Systems Loaded with Drugs for Infectious Disease Application, 2nd Edition
edited by , and Taís Maria Bauab
submission deadline 31 Dec 2026 | Viewed by 294 | Submission Open
Keywords: nanosystems; controlled drug release; infectious diseases; microbial resistance; pathogenic microorganism; drug delivery systems; nanotechnology; nanotherapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
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