Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Impact of Lipid Nanoparticle Physicochemical Properties on mRNA Vaccine
edited by
submission deadline 31 Oct 2025 | Viewed by 169 | Submission Open
Keywords: lipid nanoparticle formulation; ionizable lipids design; delivery of mRNA vaccines; sustained/controlled release; targeted delivery; stability and storage solutions; pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Gene and Cell Therapy)
Nanotechnology in Formulation of Tumor-Targeted Drug Delivery Systems submission deadline 31 Oct 2025 | Viewed by 155 | Submission Open
Keywords: nanotechnology; formulations; tumor and cancer treatment; drug delivery
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advanced Nano-Based Drug Delivery Systems for Infectious Diseases
edited by Claudio J. Salomon and Maria Celina Lamas
submission deadline 31 Oct 2025 | Viewed by 124 | Submission Open
Keywords: nanomedicines; infectious disease; microorganisms; therapeutic treatments; drug delivery systems
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Pharmaceutical Applications and Therapeutic Mechanisms of Substances from Plant Origin
edited by Iliya Zhelev Slavov, , and
submission deadline 31 Oct 2025 | Viewed by 107 | Submission Open
Keywords: natural substances; phytotherapy; phytochemistry; chromatography; pharmacokinetics; pharmacodynamics; drug delivery
(This special issue belongs to the Section Drug Targeting and Design)
Novel Approaches to Drug Delivery in Ophthalmic Disorders
edited by Letizia Pelusi and
submission deadline 31 Oct 2025 | Viewed by 104 | Submission Open
Keywords: eye diseases; ocular drug delivery; ocular barrier; conventional therapies; innovative technologies; nanoparticle carriers; injectable hydrogels; ocular implants; gene therapy in ophthalmology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Essential Oils: From Biological Activity to Pharmaceutical Applications submission deadline 31 Oct 2025 | Viewed by 100 | Submission Open
Keywords: EOs as active chemicals; EOs’ biological activity (antimicrobial; insecticidal; herbicidal; bactericidal; and fungicidal properties); EOs encapsulation procedures; EOs for improving human health; EOs in active packaging products; polymeric networks for EOs encapsulation
(This special issue belongs to the Section Drug Targeting and Design)
Technology and Preparation of Solid Dispersion for the Enhancement of Oral Bioavailability
edited by , Andreea Loredana Vonica-Tincu and
submission deadline 31 Oct 2025 | Viewed by 95 | Submission Open
Keywords: solid dispersions; poor water solubility; rational formulation design; enhancement of oral bioavailability; preparation technology
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Quality by Design in Pharmaceutical Manufacturing submission deadline 31 Oct 2025 | Viewed by 90 | Submission Open
Keywords: quality by design; critical quality attributes; pharmaceutical technology; drug product process development; process analytical technologies; patient-centric approaches; process validation; ongoing procedure performance verification; analytical quality by design; continuous manufacturing; design of experiments; clinically relevant specification; risk assessment
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Medical Applications of Chitosan Nanoparticles submission deadline 31 Oct 2025 | Viewed by 81 | Submission Open
Keywords: chitosan; chitosan-based nanoparticles; drug delivery; biopolymers; polysaccharide; biomaterials; health concerns
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanotechnology-Driven Drug Repurposing: A Novel Strategy for Targeted Drug Delivery and Pharmacokinetic Enhancement submission deadline 31 Oct 2025 | Viewed by 79 | Submission Open
Keywords: nanotechnology; drug repurposing; targeted drug delivery; pharmacokinetics; nanocarriers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Metal Complexes as Antimicrobial Agents: Pharmacokinetics and Drug Development Implications submission deadline 31 Oct 2025 | Viewed by 74 | Submission Open
Keywords: metal complexes; antimicrobial agents; drug development; therapeutic agents; pharmacokinetics
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Impacts of the Kallikrein–Kinin System in Cancer and Its Treatment: A Focus on Drug Delivery and Formulations
edited by Indiara Brusco and
submission deadline 31 Oct 2025 | Viewed by 73 | Submission Open
Keywords: cancer pathophysiology; cancer pain; adverse effects of chemotherapy; cancer-related pain mechanisms; tumor microenvironment; kininogens; kininases; kinin B1 and B2 receptors; anticancer treatment; kinin B1 and B2 receptor antagonists; drug delivery; drug formulations; nanoparticles; liposomes; polymeric micelles; prodrugs
(This special issue belongs to the Section Biologics and Biosimilars)
Medical Applications of Extracellular Vesicles submission deadline 31 Oct 2025 | Viewed by 71 | Submission Open
Keywords: extracelular vesicles; intercellular communication; EV characterization in health and disease; EV-based drug delivery systems; biomarkers
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Inhaled Advances: Emerging Trends in Pulmonary Drug Delivery submission deadline 31 Oct 2025 | Viewed by 61 | Submission Open
Keywords: pulmonary drug delivery; microparticles; nanomedicines; infectious diseases; lung targeting
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Lipid, Polymeric, and Albumin-Based Drug Delivery Systems
edited by and
submission deadline 31 Oct 2025 | Viewed by 49 | Submission Open
Keywords: nanoparticle; albumin nanoparticle; human serum albumin; polymeric nanoparticle; polymeric micelle; PLGA nanoparticle; lipid nanoparticle; liposome; nanomedicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Modelling and Simulation Approaches in Pharmaceutical Process Engineering
edited by Claudia Cogné and
submission deadline 31 Oct 2025 | Viewed by 47 | Submission Open
Keywords: pharmaceutical process engineering; modelling and simulation; mechanistic modelling; digital twins; machine learning; process optimisation and intensification; quality by design (QbD); process analytical technology (PAT); predictive modelling; pharmaceutical manufacturing
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Advancing HIV Prevention and Treatment: Pharmacokinetics, Pharmacodynamics, Toxicokinetics, Formulation and Delivery of Antiretroviral Drugs
edited by Julie B. Dumond
submission deadline 31 Oct 2025 | Viewed by 40 | Submission Open
Keywords: long-acting injectable antiretrovirals; PK/PD modeling of antiretrovirals; predictions of HIV PrEP effectiveness; antiretroviral toxicokinetics; novel drug delivery systems; novel dosing strategies; HIV treatment or prevention therapeutics in development; clinical pharmacokinetic studies in key populations; HIV drug delivery innovations; mannose receptor-targeted delivery
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Recent Advances in Photodynamic Therapy for Dental Diseases
edited by Patricia Comeau
submission deadline 31 Oct 2025 | Viewed by 37 | Submission Open
Keywords: photodynamic therapy; biomaterials; nanoparticles; dental; bone tissue engineering; drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Design, Development and Biomedical Applications of Hyaluronic Acid-Based Drug and Gene Delivery Systems
edited by Cristina Casadidio and Alice Spadea
submission deadline 31 Oct 2025 | Viewed by 36 | Submission Open
Keywords: hyaluronic acid; targeted drug delivery; gene delivery; CD44; nucleic acid delivery; HA conjugates; nanoparticles personalized medicine
(This special issue belongs to the Section Gene and Cell Therapy)
PLGA Micro/Nanoparticles in Drug Delivery
edited by Ilaria Arduino and
submission deadline 10 Nov 2025 | 2 articles | Viewed by 1708 | Submission Open
Keywords: micro- and nanotechnology; particle manufacturing; targeted delivery; particle characterization; biocompatibility; solubility enhancement
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Hepatic-Targeted Drug Delivery Systems submission deadline 10 Nov 2025 | Viewed by 756 | Submission Open
Keywords: hepatic drug delivery; phytotherapy; nanomedicine; lipid complexes; targeted therapies; liver diseases; drug vehicles; biomaterials; hepatocellular carcinoma; liposome; polymeric nanoparticles; lipid nanoparticles; hepatic stellate cell
(This special issue belongs to the Section Drug Targeting and Design)
Bioavailability and Bioequivalence Assessment of Topical Drug Products Intended for Local Action
edited by and Seeprarani Rath
submission deadline 15 Nov 2025 | Viewed by 26 | Submission Open
Keywords: bioequivalence; bioavailability; biowaivers; topical dosage forms for local action; topical corticosteroids; dermatopharmacokinetics; in vitro release tests (IVRTs)/in vitro permeation tests (IVPTs); pharmaceutical equivalence; semi-solid dosage forms; human skin; vasoconstrictor assay (VCA) in place of human skin
(This special issue belongs to the Section Biopharmaceutics)
Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 20 Nov 2025 | 2 articles | Viewed by 3381 | Submission Open
Keywords: drug– disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Novel Drug Delivery Systems for the Treatment of Skin Disorders submission deadline 20 Nov 2025 | 1 articles | Viewed by 1840 | Submission Open
Keywords: drug delivery; nanoparticles; vesicular systems; 3D-printed drugs; topical dosage form; skin disorder; penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Nanotechnology and RNA-Based Technologies Applied to Prophylaxis and Advanced Therapies
edited by and Vinicius Pinto Costa Rocha
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1627 | Submission Open
Keywords: RNA-technologies; nanotechnology; messenger RNA (mRNA); interference RNA (RNAi); vaccines; treatment
(This special issue belongs to the Section Gene and Cell Therapy)
Long Acting Drug Delivery Formulations
edited by Thierry Vandamme
submission deadline 20 Nov 2025 | 1 articles | Viewed by 1367 | Submission Open
Keywords: improvement in patient adherence; steady state; drug bioavailability; reduced side effect; targeted delivery; long acting; sustained release; prolonged release; pulse release; compliance
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Drug Formulation for Antiviral Therapy
edited by Chiara Medaglia
submission deadline 20 Nov 2025 | Viewed by 334 | Submission Open
Keywords: antiviral drugs development; infection; host-pathogen interactions; functional genomics
(This special issue belongs to the Section Drug Targeting and Design)
Drug Formulations Based on Chitosan and Its Derivatives for Therapeutic Applications
edited by and Zamani Cele
submission deadline 20 Nov 2025 | Viewed by 180 | Submission Open
Keywords: chitosan; chitosan derivatives; chemical modification; drug delivery biopolymers; biomedicines drug formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Antibody–Drug Conjugates Therapeutics submission deadline 20 Nov 2025 | Viewed by 85 | Submission Open
Keywords: antibody– drug conjugate; drug delivery; antibody; payload; linker; protein conjugation
(This special issue belongs to the Section Biologics and Biosimilars)
Biomaterials: Pharmaceutical Applications
edited by
submission deadline 20 Nov 2025 | Viewed by 65 | Submission Open
Keywords: natural biomaterials; synthetic biomaterials; drug delivery systems; tissue engineering; disease diagnosis; wound healing
(This special issue belongs to the Section Biopharmaceutics)
“The Power of Light” in Biomedical and Pharmaceutics: New Approaches for Photodynamic Purposes submission deadline 20 Nov 2025 | Viewed by 61 | Submission Open
Keywords: light; photosensitizers; photochemistry; photobiology; photodynamic therapy
(This special issue belongs to the Section Drug Targeting and Design)
Drug Product Performance: Bioavailability, Relative Bioavailability and Bioequivalence, 2nd Edition
edited by
submission deadline 30 Nov 2025 | 8 articles | Viewed by 10459 | Submission Open
Keywords: bioavailability; relative bioavailability; bioequivalence; biowaivers; statistical issues; regulatory issues; in vitro– in vivo correlations; physiologically-based biopharmaceutical models; physiologically-based pharmacokinetic models; qualification of models; population pharmacokinetic models; biopharmaceutical classification system; in vitro dissolution; dissolution metrics; predictive dissolution; clinical trial simulations; clinical trial optimization; healthy subjects in BA/BE trials; patients in BA/BE trials; pharmacokinetic parameters for BA/BE assessment; narrow therapeutic index drugs; highly variable drug products; immediate-release formulations; modified-release formulations; multiphasic drug products; extravascular routes of administration
(This special issue belongs to the Section Biopharmaceutics)
Inorganic Nanomaterials for the Development of Drug Delivery and Biomedical Applications
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 5036 | Submission Open
Keywords: inorganic nanoparticles; drug delivery; disease diagnosis; disease treatment; nano-biosensor; cancer theranostics; cancer imaging
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Drug Delivery Systems for the Treatment of Chronic Wound Healing
edited by Carolina Martinez and María Jimena Prieto
submission deadline 30 Nov 2025 | 4 articles | Viewed by 4057 | Submission Open
Keywords: wound healing; chronic diseases; wound repair and regeneration; drug delivery; topical formulations; biomaterial; nanotechnology; wound dressing; scar
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Hybrid Nanoparticles for Cancer Therapy
edited by Jacy Gameiro
submission deadline 30 Nov 2025 | 4 articles | Viewed by 2995 | Submission Open
Keywords: hybrid nanoparticles; cancer therapy; targeted drug delivery; nanomedicine; tumor microenvironment; gene therapy; immunotherapy; diagnostics; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Brain Tumors Treatment: Current and Future Challenges from Drug Formulations to Delivery Methods
edited by , Sara Badodi and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 2758 | Submission Open
Keywords: blood– brain barrier pathophysiology in different tumors; pediatric brain tumors; adult brain tumors; considerations for adult vs. pediatric drug delivery development; nanocarriers and nanoparticles; focused ultrasound; convection enhanced delivery; intranasal delivery; intra-arterial delivery; combination strategies
(This special issue belongs to the Section Drug Targeting and Design)
Microneedles for Drug and Vaccine Delivery
edited by
submission deadline 30 Nov 2025 | 2 articles | Viewed by 2287 | Submission Open
Keywords: physical enhancement technologies; fabrication; characterization; applications; drug delivery; cosmetic applications; diagnostic; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Naturally Derived Materials-Based Drug Delivery Systems and Their Biomedical Applications
edited by and
submission deadline 30 Nov 2025 | 3 articles | Viewed by 1656 | Submission Open
Keywords: naturally derived material; drug delivery systems; tissue engineering; regenerative medicine
(This special issue belongs to the Section Drug Delivery and Controlled Release)
In Silico Approaches of Drug–Target Interactions
edited by
submission deadline 30 Nov 2025 | 1 articles | Viewed by 1101 | Submission Open
Keywords: in silico drug discovery; drug– target interactions; virtual screening; molecular modeling; machine learning in drug design; ADME predictions
(This special issue belongs to the Section Drug Targeting and Design)
Alternative Animal Models for Nanoparticle-Based Drug Delivery: Efficacy and Toxicity Assessment submission deadline 30 Nov 2025 | 1 articles | Viewed by 971 | Submission Open
Keywords: alternative animal models; nanoparticle drug delivery; nanomedicine; toxicity assessment; bioavailability; in vivo models; biodistribution studies; therapeutic efficacy; pharmaceutical testing
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Drug Delivery Systems: From Nanotechnology to Smart Devices
edited by Mahdi Ghavami and
submission deadline 30 Nov 2025 | 1 articles | Viewed by 824 | Submission Open
Keywords: smart nanoparticles; innovative drug delivery; ingestible devices; targeted delivery systems; controlled release; microfabrication techniques; nano and microtechnology; biocompatible materials; bioavailability
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
In Vitro and In Vivo Biopharmaceutics Assessment of Silica-Based Drug Delivery Systems: Characterization, Drug Release, and Biological Performance submission deadline 30 Nov 2025 | 1 articles | Viewed by 583 | Submission Open
Keywords: drug delivery systems; mesoporous silica nanoparticles; biopharmaceutics evaluation; controlled drug release; drug release kinetics; in vivo performance; in vitro methodologies; pharmaceutical nanotechnology; stimuli-responsive systems; therapeutic efficacy
(This special issue belongs to the Section Biopharmaceutics)
Controlled Delivery of Cosmeceuticals Using Nanotechnology submission deadline 30 Nov 2025 | Viewed by 393 | Submission Open
Keywords: cosmeceuticals; skin; targeting; cosmetics; nanotechnology; delivery; formulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Carbon-Based Nanomaterials for Pharmaceutical Applications
edited by and Ivana Borišev
submission deadline 30 Nov 2025 | Viewed by 347 | Submission Open
Keywords: carbon-based nanomaterials; drug delivery; fullerenes; graphene; carbon nanotubes; nanodiamonds; carbon dots; biocompatibility; pharmaceutical applications
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advancements and Innovations in Antibody Drug Conjugates
edited by , Shivaji Edupuganti and Ebaston Thankarajan
submission deadline 30 Nov 2025 | Viewed by 339 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 30 Nov 2025 | Viewed by 297 | Submission Open
Keywords: solid dosage forms (tablets; capsules; pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
Nanoemulsions for Nose-to-Brain Drug Delivery
edited by Clóvis Orlando Pereira Da Fonseca and
submission deadline 30 Nov 2025 | Viewed by 280 | Submission Open
Keywords: nanoemulsion; intranasal; pharmacokinetics; nose-to-brain; neurology; olfactory; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Developing Drug Delivery Approaches for Both Phage Therapeutics and Phage-Based Vectors
edited by and Daniel De Vos
submission deadline 30 Nov 2025 | Viewed by 252 | Submission Open
Keywords: phage vector; drug delivery; phage therapy; phage technology
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Smart Drug Delivery Systems for Immunotherapeutic Agents submission deadline 30 Nov 2025 | Viewed by 231 | Submission Open
Keywords: immunotherapy; drug delivery systems; nanomedicine; targeted therapy; cancer immunotherapy; lipid nanoparticles; biomaterials; controlled rel ease; immunoengineering; translational medicine
(This special issue belongs to the Section Gene and Cell Therapy)
Metal Nanoparticles in Therapeutics: Pioneering Drug Delivery Systems and Tissue Engineering submission deadline 30 Nov 2025 | Viewed by 227 | Submission Open
Keywords: metal nanoparticles; drug delivery systems; tissue engineering; cancer therapy; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
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