Special Issues

Pharmaceutics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Technologies and Challenges for the Delivery of Biomacromolecular Drugs submission deadline 30 Sep 2026 | Viewed by 399 | Submission Open
Keywords: drug delivery; biomacromolecular drug; drug stability; controlled release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Multifunctional Drug Delivery Systems
edited by
submission deadline 30 Sep 2026 | Viewed by 341 | Submission Open
Keywords: multifunctional delivery systems; nanoparticles; targeting delivery; immune-modulating delivery systems; nanoparticle conjugation; sustained drug release; smart polymers; polysaccharide-based carriers; smart nanocarrier systems
(This special issue belongs to the Section Drug Delivery and Controlled Release)
The Future of CNS Therapeutics: Non-Invasive, High-Precision Nose-to-Brain Delivery Platforms submission deadline 30 Sep 2026 | 1 articles | Viewed by 340 | Submission Open
Keywords: nose-to-brain delivery; intranasal drug delivery; blood– brain barrier; central nervous system; targeting nanocarrier systems; targeted delivery platforms; nasal mucosa permeability; neuro-oncology; brain tumors; neurodegenerative diseases; drug transport mechanisms; tissue-level transport; cellular-level transport; non-invasive drug delivery; precision medicine
(This special issue belongs to the Section Drug Targeting and Design)
Emerging Trends in Smart Theranostic Nanomedicine
edited by , and Thavasyappan Thambi
submission deadline 30 Sep 2026 | Viewed by 315 | Submission Open
Keywords: various types of nanoparticles; smart nanomaterials; theranostic agents; diagnostics; synthesis and characterization; drug delivery system; in vitro and in vivo studies; synergistic therapy; cancer therapy; microbial infections; multimodal imaging; theranostics; tumor and microbial targeting
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Application of Electrospinning Technology in Pharmaceutical Engineering submission deadline 30 Sep 2026 | Viewed by 305 | Submission Open
Keywords: electrospinning; nanofibers; drug delivery; pharmaceutical engineering; controlled release; solubility enhancement; tissue engineering; wound healing; biomedical applications
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Nanoadjuvants for Drug Delivery and Immunotherapy
edited by and
submission deadline 30 Sep 2026 | Viewed by 303 | Submission Open
Keywords: adjuvants; nanoadjuvants; nano-aluminum adjuvants; nanoparticles; vaccines; immunotherapy; drug delivery system; clinical translation; biosafety
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Optimizing Drug Therapy Through Pharmacokinetics and Therapeutic Drug Monitoring
edited by Kazuro Ikawa and
submission deadline 30 Sep 2026 | Viewed by 302 | Submission Open
Keywords: dosing optimization; therapeutic drug monitoring; pharmacokinetics; pharmacodynamics; modeling and simulation; special population
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Ocular Drug Delivery and Tissue Repair Strategies submission deadline 30 Sep 2026 | Viewed by 279 | Submission Open
Keywords: ocular drug delivery; controlled drug release; biomaterials and hydrogels; targeted delivery; sustained drug release; noninvasive drug delivery
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Precision Local Drug Delivery: From Formulation Design to Local Bioavailability Assessment
edited by
submission deadline 30 Sep 2026 | Viewed by 278 | Submission Open
Keywords: locally acting dosage form; drug delivery; local delivery; semi-solid formulations; mucoadhesion; permeation; controlled release; bioequivalence assessment
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Emerging Strategies in Drug Development and Clinical Care in the Era of Personalized and Precision Medicine, 3rd Edition submission deadline 30 Sep 2026 | Viewed by 216 | Submission Open
Keywords: drug development; therapeutic strategies; preclinical and clinical drug research; drug design; drug– drug interactions; clinical care; toxicological studies; disease risk; disease prognosis and response to therapy; biomarkers identification and application; biochemistry of drug uptake; action; and metabolism; drug target discovery; individualized therapy; pharmacogenomics; novel therapeutics; non-drug-related health interferences; nutritional interventions; chronobiology; medicinal chemistry; phytochemicals; biologics; personalized medicine; precision medicine
(This special issue belongs to the Section Clinical Pharmaceutics)
Advancements and Innovations in Antibody Drug Conjugates, 2nd Edition
edited by Ebaston Thankarajan and
submission deadline 30 Sep 2026 | Viewed by 214 | Submission Open
Keywords: antibody– drug conjugates; monoclonal antibodies; targeted therapies; linker technologies; site-specific conjugation; bioimaging; pharmacokinetics; therapeutic index; next-generation ADCs; drug resistance; bispecific antibodies; combination therapies; off-target toxicity; efficacy and safety; tumor-specific antigens
(This special issue belongs to the Section Drug Targeting and Design)
Advancing Drug Delivery Systems and Pharmaceutical Formulations submission deadline 30 Sep 2026 | Viewed by 213 | Submission Open
Keywords: drug delivery systems; pharmaceutical formulations; active pharmaceutical ingredients; bioavailability; nanoscale systems; lipid-based carriers; polymer-based carriers; amorphous formulations; solid-state formulations; hybrid materials; controlled release; stimuli-responsive delivery; site-specific delivery; physicochemical characterization; biopharmaceutical evaluation; in vitro-in vivo correlation; translational research; quality-by-design; scalable manufacturing; therapeutic efficacy
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pharmacokinetic Perspectives on Drug Interactions in Therapy submission deadline 30 Sep 2026 | Viewed by 201 | Submission Open
Keywords: drug– drug interactions (DDIs); drug metabolism; cytochrome P450; transport proteins; computational modeling; physiologically based pharmacokinetic (PBPK) model
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Polymer-Based Nanotechnology Delivery Systems for Nucleic Acids submission deadline 30 Sep 2026 | Viewed by 198 | Submission Open
Keywords: polymer-based nanoparticles; nucleic acid delivery systems; therapeutic nucleic acids (TNAs); cancers; vaccines; cardiovascular diseases; polymeric micelles; dendrimers; polyplexes; mRNA and gene editing delivery approaches; translational and preclinical studies
(This special issue belongs to the Section Gene and Cell Therapy)
Novel Approaches for Insulin Delivery
edited by Charles W. Putnam and Klearchos K. Papas
submission deadline 30 Sep 2026 | Viewed by 193 | Submission Open
Keywords: insulin; insulin pharmacokinetics; beta cells; stem cells; genetically modified; devices; routes of administration; delivery; novel; cell therapy
(This special issue belongs to the Section Pharmaceutical Technology, Manufacturing and Devices)
Next-Generation Cholinesterase Inhibitors for Alzheimer's Disease: New Targets and Strategies
edited by Josélia A Lima and
submission deadline 30 Sep 2026 | Viewed by 183 | Submission Open
Keywords: Alzheimer’ s disease; acetylcholinesterase; butyrylcholinesterase; multi-target ligands; metal quelation; neuroinflammation; PAS; amyloid-beta; tau; MAO-B; pharmacokinetic/pharmacodynamic (PK/PD)
(This special issue belongs to the Section Drug Targeting and Design)
Drug Nanocarriers for Pharmaceutical Applications, 2nd Edition
edited by
submission deadline 30 Sep 2026 | Viewed by 157 | Submission Open
Keywords: drug nanocarriers; nanomedicine; physicochemical properties; cancer targeting; antibiotic resistance; bioelements
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Where Are We Now and Where Is Cell Therapy Headed? (2nd Edition) submission deadline 15 Oct 2026 | 2 articles | Viewed by 2924 | Submission Open
Keywords: stem cells; mesenchymal stromal cells; cell therapy; CAR-T; CAR-NK; cancer; gene therapy; organoids and organ on a chip; extracellular vesicles; secretome
(This special issue belongs to the Section Gene and Cell Therapy)
Vesicle-Based Drug Delivery Systems
edited by and Paula Messina
submission deadline 20 Oct 2026 | 3 articles | Viewed by 13478 | Submission Open
Keywords: liposomes; exosomes; extracellular vesicles; niosomes; polymersomes; active and passive targeting; pharmacokinetics; isolation/synthesis; functionalization; modified release
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Targeted Therapies and Drug Delivery for Neurodegenerative Diseases
edited by and Chiara Lucchi
submission deadline 20 Oct 2026 | 5 articles | Viewed by 12021 | Submission Open
Keywords: targeted drug delivery; blood– brain barrier; neurodegenerative disease treatment; precision medicine; neuroscience
(This special issue belongs to the Section Drug Targeting and Design)
Application of Marine-Derived Polymers in Drug Dosage Forms submission deadline 20 Oct 2026 | 3 articles | Viewed by 5562 | Submission Open
Keywords: pharmaceutical formulations; controlled drug release; biological activity of drug fromulations; marine-derived polymers; alginates; chitosan; fucoidan
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Recent Advances in Antimicrobial Drug Delivery
edited by and
submission deadline 20 Oct 2026 | 3 articles | Viewed by 3610 | Submission Open
Keywords: antimicrobial drug delivery; nanoparticles; controlled release; targeted therapy; antimicrobial resistance; nanomedicine; smart drug delivery systems; surface modification; biofilm treatment; advanced drug delivery strategies
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Biopolymer Nanoparticles for Targeted Therapy in Cardiovascular Diseases
edited by Lino Sánchez-Segura and Silvio Zaina
submission deadline 20 Oct 2026 | 1 articles | Viewed by 1746 | Submission Open
Keywords: nanoparticles; biopolymers; drug-load; drug delivery; target; cardiovascular disease; therapy
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advanced Nanotechnology-Based Strategies for Ocular Diseases Treatment
edited by and Andreia Martins Rosa
submission deadline 20 Oct 2026 | Viewed by 166 | Submission Open
Keywords: biomaterials; nanoparticles; gene therapy; regenerative medicine; theranostics; natural products
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Cutting-Edge Drug Delivery and Nanomedicine: Innovations in Hybrid Systems, Theranostics and Targeted Therapies submission deadline 25 Oct 2026 | 6 articles | Viewed by 15811 | Submission Open
Keywords: drug delivery; nanomedicine; hybrid nanosystems; targeted therapies; theragnostic; drug repurposing; PDT; PTT
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Population Pharmacokinetics and Its Clinical Applications, 2nd Edition submission deadline 25 Oct 2026 | Viewed by 183 | Submission Open
Keywords: model-informed precision dosing (MIPD); therapeutic drug monitoring (TDM); dosing adjustments; special populations; nonlinear mixed-effects modeling (NONMEM); PK/PD models
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Solid Dispersions for Drug Delivery: Development, Preparation and In Vitro/In Vivo Characterization, 2nd Edition submission deadline 25 Oct 2026 | Viewed by 151 | Submission Open
Keywords: solid dispersion; poorly soluble drugs; stability; dissolution properties; molecular interaction; polymers
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Physiologically Based Pharmacokinetic (PBPK) Modeling and Applications
edited by
submission deadline 29 Oct 2026 | 6 articles | Viewed by 15973 | Submission Open
Keywords: physiologically based pharmacokinetic (PBPK) modeling; IVIVE; pharmacokinetics; ADME; modeling and simulation; PK/PD; biopharmaceutics; quantitative systems pharmacology
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
Topical Drug Delivery for Skin Diseases
edited by Rudolf E. Schopf
submission deadline 30 Oct 2026 | Viewed by 416 | Submission Open
Keywords: topical drug delivery; skin diseases; psoriasis; eczema; nanotechnology; liposomes; ethosomes; microneedles; hydrogels; controlled release; dermal penetration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Recent Advances in Non-Viral Vectors for Gene Therapy and Gene Delivery
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 7279 | Submission Open
Keywords: non-viral gene delivery; lipid nanoparticle; polymeric carrier; endosomal escape; genome editing delivery
(This special issue belongs to the Section Gene and Cell Therapy)
Development and Optimization of Buccal Films Formulations
edited by and Krisztián Pamlényi
submission deadline 31 Oct 2026 | 3 articles | Viewed by 7144 | Submission Open
Keywords: buccal drug delivery; mucoadhesive; polymer films; buccal tablets; solid dosage forms; controlled drug release; fast dissolving formulations; permeability enhancement; pediatric formulations; geriatric formulations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Advances in Solid and Semi-Solid Dosage Form Design for Enhanced Biopharmaceutical Performance submission deadline 31 Oct 2026 | 2 articles | Viewed by 6968 | Submission Open
Keywords: solid dosage forms (tablets; capsules; pellets); novel formulation strategies; bioavailability enhancement; amorphous solid dispersions; lipid-based formulations; pharmaceutical cocrystals; excipient functionality and drug release; 3D printing in pharmaceuticals; hot melt extrusion (HME); spray drying in drug formulation; co-processing techniques; controlled and sustained drug release; targeted drug delivery systems; in vitro/in vivo correlation (IVIVC); quality-by-design (QbD) in pharmaceutics
(This special issue belongs to the Section Biopharmaceutics)
Advances in Nanotechnology-Based Drug Delivery Systems, 2nd Edition
edited by
submission deadline 31 Oct 2026 | 4 articles | Viewed by 6772 | Submission Open
Keywords: biomaterials; nanomedicine; nanotechnology; formulations; green production technologies; biological macromolecule nanoencapsulation
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Nanoparticle-Based Drug Formulation for Enhancing Nose-to-Brain Delivery
edited by and Richard Nii Lante Lamptey
submission deadline 31 Oct 2026 | 3 articles | Viewed by 6199 | Submission Open
Keywords: nanoparticles; nose-to-brain drug delivery; blood– brain barrier (BBB); central nervous system (CNS); neurodegenerative diseases; targeted therapeutics; non-invasive delivery; intranasal administration
(This special issue belongs to the Section Drug Delivery and Controlled Release)
From Nature to Pharmacy: Advances in Bio-Based Pharmaceutical Formulations submission deadline 31 Oct 2026 | 4 articles | Viewed by 5824 | Submission Open
Keywords: natural products; drug delivery systems; bioactive ingredients; nanotechnology; bioavailability; pharmaceutical formulations; plant-derived compounds; biocompatible carriers
(This special issue belongs to the Section Biopharmaceutics)
Ocular Drug Delivery System submission deadline 31 Oct 2026 | 3 articles | Viewed by 4725 | Submission Open
Keywords: drug delivery; nanoparticles; controlled release; hydrogels; liposomes; microneedle arrays
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Functionalized Polymers for Anticancer Applications
edited by Alejandro Ramirez-Jimenez, and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 4298 | Submission Open
Keywords: photodynamic therapy; photothermal therapy; sonodynamic therapy; immunotherapy; smart polymeric nanocarriers; specific drug delivery; functionalized polymers; anticancer drug delivery; metallodrugs; theragnostic
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advanced Nano-Based Drug Delivery Systems for Infectious Diseases
edited by Claudio J. Salomon and Maria Celina Lamas
submission deadline 31 Oct 2026 | 1 articles | Viewed by 3784 | Submission Open
Keywords: nanomedicines; infectious disease; microorganisms; therapeutic treatments; drug delivery systems
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Optimizing Aerosol Therapy: Strategies for Pulmonary Drug Delivery submission deadline 31 Oct 2026 | 3 articles | Viewed by 3375 | Submission Open
Keywords: pulmonary drug delivery; aerosol therapy; inhalation drug delivery; particle engineering; inhaled biologics and vaccines; aerosol characterization; in vitro-in vivo correlation (IVIVC); inhaler devices; lung deposition; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Engineering of Advanced Nanocarriers and Extracellular Vesicle Systems for Precision Drug Delivery
edited by , Eugenia Romano and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 3114 | Submission Open
Keywords: nanomedicine; extracellular vesicles; hybrid nanocarriers engineered nanoparticles; surface functionalization; biomimicry; drug delivery; clinical translation
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advancing Precision Diagnosis and Therapy with Targeted Radiopharmaceuticals in Cancer and Systemic Diseases submission deadline 31 Oct 2026 | 3 articles | Viewed by 2758 | Submission Open
Keywords: radiopharmaceuticals; diagnostics imaging; theranostics; radionuclides; radioligand therapy; cancer; neurological disorders; dosimetry; preclinical studies; clinical studies; clinical translation
(This special issue belongs to the Section Drug Targeting and Design)
Targeted Drug Delivery Strategies for Infectious Diseases
edited by Danielle Lazarin Bidóia, Daniele Stéfanie Sara Lopes Lera-Nonose and
submission deadline 31 Oct 2026 | 2 articles | Viewed by 2390 | Submission Open
Keywords: infectious disease; treatment; delivery system; biomaterial; targeted drug therapy; liposome; dendrimer; nanotube; nanotechnology; formulation; polymer; antifungal; antimicrobial; antiparasitic; antibiotic; bacterial infection; adjuvant; antiviral; biofilm-related infection; bacteria; antiparasitic
(This special issue belongs to the Section Drug Targeting and Design)
Recent Advances in Drug Delivery Through Microneedle-Based Systems submission deadline 31 Oct 2026 | 1 articles | Viewed by 2274 | Submission Open
Keywords: microneedle-based systems; microneedles; micro array patches; skin delivery; transdermal delivery; vaccination
(This special issue belongs to the Section Drug Delivery and Controlled Release)
New Era in Antimicrobial Strategies
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 2202 | Submission Open
Keywords: artificial intelligence; phage therapy; microbiome; host-directed therapy; nanoparticles; precision medicine; antimicrobial agents; drug repositioning
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Drug Delivery Strategies and Novel Approaches for Cancer Treatment submission deadline 31 Oct 2026 | 1 articles | Viewed by 1883 | Submission Open
Keywords: nanocarriers; drug delivery; cancer therapy; targeted delivery; drug repurposing; controlled release; nanotechnology; anticancer agents
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Innovative Oral and Topical Drug Delivery Systems: Formulation Design, Optimization and Quality Control
edited by , Alvaro Jimenez-Kairuz and José Bermudez
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1243 | Submission Open
Keywords: oral formulations; topical formulations; lipid-based delivery systems; polymeric delivery systems; mucoadhesive platforms; micro/nanoparticulate carriers; stimuli-responsive delivery systems; polymeric hydrogels; vesicles; solid dispersions; co-crystals; complexes; in situ forming systems; pharmaceutical formulations; bioavailability enhancement; solubility and permeability improvement; 3D printing in pharmaceutics; Quality by Design (QbD); hot-melt extrusion; pharmaceutical quality control
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Advances in Natural Anticancer Formulation submission deadline 31 Oct 2026 | 1 articles | Viewed by 1044 | Submission Open
Keywords: cancer treatment; phytocompounds; drug formulations; natural-based therapies; in vitro and ex vivo toxicity evaluation; in vivo drug sensitivity; in silico models; pharmacokinetics/pharmacodynamics; innovations
(This special issue belongs to the Section Physical Pharmacy and Formulation)
Metal–Organic Frameworks for Pharmaceutical Applications
edited by Arvin Eskandari
submission deadline 31 Oct 2026 | 1 articles | Viewed by 849 | Submission Open
Keywords: metal– organic frameworks (MOFs); drug delivery systems; controlled release; theranostics; biomedical imaging; biocompatibility and stability; MOF composites; hybrid MOF materials; oral and implantable delivery; artificial intelligence (AI) and machine learning (ML); translational pharmaceutics
(This special issue belongs to the Section Nanomedicine and Nanotechnology)
Advances in Nanoemulsion for Drug Delivery
edited by Feng Zhang and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 804 | Submission Open
Keywords: nanoemulsion formulations and stability; topical delivery; poorly soluble drugs; targeted drug and biologics delivery; theranostic platform and imaging; vaccines and adjuvants; cancer; infectious diseases; pulmonary diseases
(This special issue belongs to the Section Drug Delivery and Controlled Release)
Pathophysiological Influences on Pharmacokinetics and Pharmacodynamics, 2nd Edition
edited by Geraldo Duarte, Fernanda de Lima Moreira and Jhohann Richard de Lima Benzi
submission deadline 31 Oct 2026 | 1 articles | Viewed by 624 | Submission Open
Keywords: drug– disease interactions; pharmacokinetics; pharmacodynamics; pharmacotherapy
(This special issue belongs to the Section Pharmacokinetics and Pharmacodynamics)
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