Stem Cell Therapy and Nanodelivery Systems for Tissue Engineering

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 2975

Special Issue Editor


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Guest Editor
Department of Biomedical Engineering, Dongguk University-Seoul, Seoul 04620, Republic of Korea
Interests: tissue regeneration; cartilage regeneration; biomaterials; multipotent stem cells; cell-based drug delivery system

Special Issue Information

Dear Colleagues,

Stem cells possess remarkable potential for tissue regeneration due to their differentiation and proliferative capabilities. Utilizing biomaterials that can modulate the biophysical and biochemical cues of stem cells represents a powerful strategy to enhance their regenerative efficacy. Biomaterials refer to materials that are biocompatible and suitable for in vivo applications. By studying and elucidating the interaction mechanisms between these biomaterials and stem cells, we can improve the regenerative efficacy and ultimately contribute to the treatment of human diseases, thereby extending the human lifespan and improving quality of life.

This Special Issue will cover the use of various biomaterials—such as nanoparticles, hydrogels, and naturally derived or synthetic polymers—in the application of multipotent stem cells for tissue regeneration. It aims to provide researchers in the field with knowledge ranging from basic to applied research. We invite articles on all aspects of the use of biomaterials and multipotent stem cells for tissue regeneration.

Dr. Yoshie Arai
Guest Editor

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Keywords

  • biomaterials
  • multipotent stem cells
  • tissue regeneration
  • adult stem cells
  • induced pluripotent stem cells
  • cell engineering
  • tissue engineering
  • organoid

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Published Papers (1 paper)

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Review

30 pages, 2878 KiB  
Review
Exosome Source Matters: A Comprehensive Review from the Perspective of Diverse Cellular Origins
by Yiru Chen, Weikun Qi, Zhenghao Wang and Feng Niu
Pharmaceutics 2025, 17(2), 147; https://doi.org/10.3390/pharmaceutics17020147 - 22 Jan 2025
Cited by 1 | Viewed by 2643
Abstract
Exosomes have emerged as promising therapeutic agents in regenerative medicine. This review introduces a novel cell type-oriented perspective to systematically analyze exosomal properties in regenerative therapies. To our knowledge, this review is the first to comprehensively compare exosomes based on cellular source type, [...] Read more.
Exosomes have emerged as promising therapeutic agents in regenerative medicine. This review introduces a novel cell type-oriented perspective to systematically analyze exosomal properties in regenerative therapies. To our knowledge, this review is the first to comprehensively compare exosomes based on cellular source type, offering unprecedented insights into selecting optimal exosome producers for targeted regenerative applications. Factors beyond cellular origin influencing exosomal therapeutic efficacy, such as donor sites and collection methods, are also explored here. By synthesizing key advances, we propose promising research directions in the end. We aim to accelerate the development of more effective exosome-based regenerative therapies and highlight underexplored directions in this rapidly evolving field. Full article
(This article belongs to the Special Issue Stem Cell Therapy and Nanodelivery Systems for Tissue Engineering)
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