Natural Compounds in Drug Delivery Systems

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 74

Special Issue Editors


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Guest Editor
Department of Agricultural Sciences and Food Engineering, Faculty of Agricultural Sciences, Food Industry and Environmental Protection, “Lucian Blaga” University of Sibiu, 7-9 Dr. I. Ratiu St., 550012 Sibiu, Romania
Interests: natural compounds; phytochemical analysis; antioxidant activity; volatile oils; food sciences
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Preclinical Department, Faculty of Medicine, “Lucian Blaga” University of Sibiu, 2A Lucian Blaga St., 550169 Sibiu, Romania
Interests: natural products; drug delivery; analytical methods; biochemistry; laboratory tests; antioxidants; dendrimers; pharmacovigilance
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Preclinical Department, Faculty of Medicine, “Lucian Blaga” University of Sibiu, 2A Lucian Blaga St., 550169 Sibiu, Romania
Interests: natural products; antioxidants; phytochemicals; nutrivigilance; toxicology; dendrimers; drug delivery
Special Issues, Collections and Topics in MDPI journals
Preclinical Department, Faculty of Medicine, “Lucian Blaga” University of Sibiu, 2A Lucian Blaga St., 550169 Sibiu, Romania
Interests: natural products; phytochemical analyses; antioxidants; polyphenols; environmental sciences; dendrimers; drug delivery; nutrivigilance
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Preclinical Department, Faculty of Medicine, “Lucian Blaga” University of Sibiu, 2A Lucian Blaga St., 550169 Sibiu, Romania
Interests: natural products; drug delivery; dendrimers; analytical methods; antioxidants; pharmacovigilance
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Agricultural Sciences and Food Engineering, Faculty of Agricultural Sciences, Food Industry and Environmental Protection, “Lucian Blaga” University of Sibiu, 7-9 Dr. I. Ratiu St., 550012 Sibiu, Romania
Interests: natural compounds; antimicrobial activity; food sciences; food technology

Special Issue Information

Dear Colleagues,

Natural compounds are bioactive molecules found in vegetables, fruits, and various plants, known for their complex actions and multiple benefits to human health. The current trend in scientific and medical research is to harness these compounds, which, due to their antioxidant, antimicrobial, anti-inflammatory, and other properties, offer the potential to replace chemically synthesized substances commonly used in pharmaceuticals.

However, a significant scientific challenge lies in the replacement of synthetic substances with natural ones derived from local raw materials. Their integration into stable and effective drug delivery systems is a difficult task due to their lower chemical stability when compared to synthetic molecules, thus making it a strategic and technical issue that requires innovative solutions.

Modern pharmaceutical technologies have emerged as effective strategies for enhancing the stability and bioavailability of natural and biologically active compounds. These innovative formulations protect sensitive natural molecules from degradation.

Microencapsulation, nanoencapsulation, and liposomal delivery systems are several encapsulation techniques that help to preserve the integrity of natural compounds, control their release, and improve their absorption in the body. As a result, such advanced formulations represent a promising approach to developing stable, effective, and safe natural-based drugs, making the transition from synthetic to natural substances more feasible in modern medicine.

Since this topic is of real interest to the scientific community, this Special Issue will provide readers with an overview of the current advances in the field of natural compounds in drug delivery systems.

Dr. Cecilia Georgescu
Prof. Dr. Felicia-Gabriela Gligor
Dr. Carmen Maximiliana Dobrea
Dr. Adina Frum
Dr. Anca Butuca
Dr. Monica Mironescu
Guest Editors

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Keywords

  • natural products
  • extraction techniques
  • phytochemical analyses
  • natural compounds
  • biological active compounds
  • new formulations
  • encapsulated technics
  • biotechnology
  • drug delivery systems
  • bioavailability
  • pharmacy

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Published Papers

This special issue is now open for submission.
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