Microparticle-Based Drug Delivery Systems
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 21
Special Issue Editors
Interests: degradable polymers; drug delivery systems; inhalable formulations; microparticles; nanoparticles; hydrogels; scaffolds
Special Issues, Collections and Topics in MDPI journals
Interests: polyanhydrides; microspheres; cytostatic activity; controlled drug delivery systems; biodegradable polymers; micelles
Special Issue Information
Dear Colleagues,
In recent years, intensive research has been conducted on controlled drug release systems. The use of drug carriers in the treatment of many diseases brings a number of benefits, such as increasing therapeutic effectiveness while reducing the dose used; reducing toxicity; the ability to administer a constant, precisely defined dose of drugs for a long period of time; and control of a drug's biodistribution and its pharmacokinetics.
Microparticles are a useful form of drug delivery system because they can be used to encapsulate, protect, and control the release of a wide range of drugs. Microspheres have been investigated for use in the controlled release of drugs, such as chemotherapeutic agents, local anesthetics, anticoagulants, neuroactive drugs, and anticancer agents. They can be easily administered orally, in the form of injections, or as inhalable pulmonary systems. When delivered with use of a microparticle system, toxic and insoluble drugs can be administered at lower frequency and in smaller quantity.
Microparticles can be obtained from a range of materials, including biodegradable polymers. The advantage of using biodegradable polymers is their ease of removal of the degradation products from the organism due to their low molecular weight. Furthermore, by controlling the rate of polymer degradation, it is possible to manipulate the rate of release of active substances.
This Special Issue aims to showcase research regarding preparing and characterizing novel microparticle-based carriers for the delivery of biologically active compounds. Detailed characteristics of such drug delivery systems in the context of potential applications, and deeper discussions on the relationship between the surface morphology of microparticles and the properties of the carriers obtained from them, are also welcome.
Prof. Dr. Elżbieta Pamuła
Dr. Daria Niewolik
Guest Editors
Manuscript Submission Information
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Keywords
- drug delivery systems
- microparticles
- biodegradable polymers
- bioactive compounds
- biomedical applications
- biocompatibility
- biological properties
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