Advancements in Pro-Regenerative Hydrogel Scaffolds for Tissue Engineering and Regenerative Medicine
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 3524
Special Issue Editors
Interests: biomaterials; polymeric drug delivery systems; tissue engineering; scaffolds; wound healing; controlled and targeted drug delivery; multi-target drug delivery systems
Special Issues, Collections and Topics in MDPI journals
2. University Clinical Center of Serbia, Clinic of Dermatology and Venerology, 11000 Belgrade, Serbia
Interests: wound healing; autoimmune blistering disorders; biologics in dermatology; wound tissue regeneration
Special Issue Information
Dear Colleagues,
We are delighted to introduce the Special Issue of Pharmaceutics, entitled “Advancements in Pro-Regenerative Hydrogel Scaffolds for Tissue Engineering and Regenerative Medicine”, which focuses on the latest advancements in pro-regenerative hydrogel scaffold engineering for regenerative medicine. The developments in the fields of tissue engineering and regenerative medicine are fundamentally inspired by the goal of addressing a broad spectrum of clinical challenges, especially those related to replicating environments of native tissue by a single approach. One of the revolutionary strategies in the field of tissue engineering/regeneration is the use of 3D pro-regenerative hydrogel scaffolds with superior biomimicry and bioactivity.
The pro-regenerative hydrogel scaffolds are capable of adapting to the dynamic tissue regeneration/engineering processes, providing a biomimetic environment that supports cellular processes and interactions as well as the formation of health tissue in three dimensions through a replicated extracellular matrix (ECM). Additional regenerative properties of these pro-regenerative hydrogel scaffolds could be engineered by loading them with different bioactive agents, including cells, growth factors, antimicrobial and anti-inflammatory agents, or multiple bioactive agents that promote tissue regeneration processes. Various synthetic monomers and natural polymers possess significant biophysiological potential for the design of pro-regenerative hydrogel scaffolds for tissue engineering/regeneration, such as 2-hydroxyethyl (meth)acrylate, gelatin, alginate, chitosan, hyaluronic acid, and collagen, but the engineering of pro-regenerative hydrogel scaffolds that simultaneously provide biophysiological support for cellular processes and precisely mimic the anatomical shapes and microstructures crucial for effective tissue regeneration presents further challenges in both the design and synthesis of these hydrogel scaffolds.
The goal of this Special Issue is to highlight advancements in the area of pro-regenerative hydrogel scaffolding biomaterials for applications in tissue engineering and regenerative medicine. Of special interest are papers that present innovative strategies for the engineering of pro-regenerative hydrogel scaffolds for bone regeneration, wound healing, cartilage, and nerve reparation, as well as papers that cover the engineering of 3D tumor tissue for clinical trials of novel active agents. We believe that the topic of this Special Issue will stimulate groundbreaking research and attract significant interest from a wide audience in the field of pro-regenerative hydrogel scaffolds for tissue engineering and regenerative medicine. We look forward to receiving your contributions.
Dr. Marija M. Babić Radić
Dr. Dubravka P. Živanović
Guest Editors
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Keywords
- pro-regenerative scaffolds for tissue engineering
- ECM-like hydrogel substitutes
- scaffolds for wound healing
- scaffolds for bone and cartilage regeneration
- scaffolds for nerve reparation
- bioactive 3D scaffolds
- scaffolds for engineering of 3D tumor tissue
- multi-biofunctional scaffolds for tissue regeneration
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