Phytocompounds-Based Formulations for Anti-Inflammatory Disorders

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".

Deadline for manuscript submissions: 10 May 2025 | Viewed by 763

Special Issue Editor


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Guest Editor
Department of Bromatology and Pharmacognosy, Faculty of Pharmacy of the University of Coimbra, University of Coimbra, Coimbra, Portugal
Interests: phytochemistry; natural compounds; anti-inflammatory activity; antioxidant activity; formulation development

Special Issue Information

Dear Colleagues,

Inflammation is a complex biological process that occurs in response to injury, infection, or other stimuli. It is essential for the body to protect itself and initiate repair. However, in certain conditions, the inflammatory process may reach such intensity or duration that it becomes undesirable for the patient. Phytocompounds offer a promising avenue for the development of novel anti-inflammatory formulations. Natural compounds often have fewer adverse effects compared to synthetic drugs, making them more suitable for long-term use. These kinds of compounds can interact with biological targets in unique ways, potentially offering new therapeutic approaches. Centuries of ethnopharmacological use make plants an almost infinite source of potentially effective drugs in the treatment of inflammatory diseases.

We are pleased to invite you to contribute to our Special Issue Phytocompounds-Based Formulations for Anti-inflammatory Disorders. This Special Issue aims to highlight the most novel breakthroughs in the treatment of inflammatory conditions by phytocompounds. Research areas may include (but are not limited to) the following: natural or hemi-synthetic compounds, plant extracts and/or fractions, anti-inflammatory properties, conventional pharmaceutical forms, liposomes, nanocapsules, and/or drug targeting, applied to in vitro, in vivo, or in silico anti-inflammatory therapies.

I look forward to receiving your contributions.

Dr. Gustavo Costa
Guest Editor

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Keywords

  • phytocompounds
  • natural compounds
  • phytotherapy
  • plant-based drugs
  • anti-inflammatory
  • pharmaceutical forms

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Published Papers (1 paper)

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Review

16 pages, 1126 KiB  
Review
Synthesis Mechanism and Therapeutic Effects of Thiosulfinates and Polysulfides of Different Species of Garlic from the Allium Genus
by Ana Montserrat Corona-España, Mario Alberto García-Ramírez, Ingrid Mayanin Rodríguez-Buenfil, Jorge Iván Delgado-Saucedo and Orfil González-Reynoso
Pharmaceutics 2025, 17(4), 437; https://doi.org/10.3390/pharmaceutics17040437 - 28 Mar 2025
Viewed by 397
Abstract
The genus Allium contains more than 300 species where garlic, onion and leek can be found. Recent studies highlight the potential of phytochemicals present in the genus Allium as therapeutic agents, such as antimicrobial, antihypertensive, antioxidant and antiinflammatory, which makes it a widely [...] Read more.
The genus Allium contains more than 300 species where garlic, onion and leek can be found. Recent studies highlight the potential of phytochemicals present in the genus Allium as therapeutic agents, such as antimicrobial, antihypertensive, antioxidant and antiinflammatory, which makes it a widely studied genus and an attractive option for both the pharmaceutical and food industries. This review aims to explore the current knowledge in this field. It highlights key findings regarding the pharmacological approach on thiosulfinates and polysulfides for Allium sativum, Allium ampeloprasum and Allium sphaerocephalon species. Further, by integrating what has been reported in previous research, this review proposes an action mechanism for the formation of thiosulfinates and polysulfides, which will help harness the therapeutic potential of nature-inspired solutions in combating illness. Full article
(This article belongs to the Special Issue Phytocompounds-Based Formulations for Anti-Inflammatory Disorders)
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