The Exciting Opportunities That Radiopharmaceuticals Have to Offer: Nuclear Medicine Imaging, Therapy and Drug Delivery Systems
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: closed (30 November 2025) | Viewed by 186
Special Issue Editors
Interests: PET imaging; radiochemistry; molecular imaging probes; neuroimaging; radiopharmaceutical development
2. Laboratory of Nanoradiopharmacy, Rio de Janeiro State University, Rio de Janeiro 23070-200, Brazil
Interests: radiopharmacy; radiopharmaceuticals; nano-radiopharmaceuticals; nanotechnology; nanoparticles and theranostics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Radiopharmaceuticals play a transformative role in nuclear medicine by enabling both precise imaging and targeted treatment at the molecular level. With the growing need for non-invasive diagnostic tools and effective site-specific therapies, this field offers unprecedented opportunities across oncology, neurology, cardiology, and more. Recent innovations in radiochemistry, molecular probe design, and drug delivery platforms have significantly enhanced the specificity, bioavailability, and therapeutic index of these agents. Advances in targeted radionuclide therapy (TRT), including alpha- and beta-emitting isotopes, have opened up new therapeutic pathways for combatting cancer and inflammatory diseases. At the same time, engineering drug delivery systems—such as nanocarriers and ligand-conjugated scaffolds—has improved the in vivo stability, biodistribution, and cell/tissue penetration of radiopharmaceuticals.
This Special Issue aims to gather original research and reviews on cutting-edge developments in the design, synthesis, and application of radiopharmaceuticals for both diagnostic and therapeutic purposes. Topics of interest include novel imaging probes, PET/SPECT tracers, theranostic agents, and innovative drug delivery approaches for crossing biological barriers. Contributions highlighting the translational and clinical potential of radiopharmaceuticals are particularly welcome. We hope this collection will provide new insights into how radiopharmaceuticals are reshaping modern medicine.
Dr. Yanli Wang
Dr. Ralph Santos-Oliveira
Guest Editors
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Keywords
- PET imaging
- theranostics
- molecular imaging probes
- radionuclide therapy
- neuroimaging
- radiochemistry
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