Ocular Drug Delivery Systems and Formulations
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 December 2025 | Viewed by 10
Special Issue Editor
2. Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Interests: drug delivery systems; pharmaceutics; nanoparticles; cyclodextrins; ophtalmic formulations
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Efficient drug delivery to ocular tissues remains a challenge due to the eye’s unique anatomical and physiological barriers. These barriers limit drug absorption, bioavailability, and therapeutic efficacy. In response, recent advances in the development of nanoscale drug delivery systems and novel biomaterials have opened new possibilities for targeted and sustained ocular therapies.
Innovative formulations—such as nanoparticles, liposomes, dendrimers, hydrogels, in situ gelling systems, and biodegradable implants, among others—offer enhanced drug stability, controlled release, prolonged residence time, and the ability to overcome conventional delivery limitations. These strategies enhance the penetration of therapeutic agents through ocular tissues, improving the treatment of different ocular structures, minimizing systemic absorption, and reducing potential side effects.
This Special Issue provides a comprehensive overview of recent advances in ocular drug delivery, focusing on cutting-edge formulations and delivery systems that are designed to overcome various ocular barriers.
By emphasizing the synergy between material science, pharmaceutical technology, and ocular biology, this Special Issue aims to inform and inspire future research toward more effective and patient-friendly ocular therapeutics.
Dr. Victoria Díaz-Tomé
Guest Editor
Manuscript Submission Information
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Keywords
- ocular drug delivery
- ophthalmic formulations
- ophthalmic drug bioavailability
- ophthalmic hydrogels
- ophthalmic pharmaceutical nanotechnology
- ocular therapies
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