Advanced Drug Delivery Systems for Natural Products

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 43

Special Issue Editors


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Guest Editor
Department of Pharmaceutical Technologies, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria
Interests: emulsion polymerization; drug stability; pharmaceutical nanotechnology; pharmaceutical research and development; pharmacokinetics
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pharmaceutical Technologies, Faculty of Pharmacy, Medical University of Varna, 9000 Varna, Bulgaria
Interests: vesicular systems; niosomes; stimuli-sensitive nanocarriers; inorganic nanoparticles
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, 9002 Varna, Bulgaria
Interests: natural products; phytotherapy; HPLC; in vivo modeling; pharmacology; toxicology; pharmacokinetics

Special Issue Information

Dear Colleagues,

Even in the era of technological advancement, natural products play a pivotal role in drug development, offering a vast repertoire of bioactive molecules with diverse pharmacological properties. However, their clinical potential is often constrained by their poor solubility and permeability, low bioavailability, rapid metabolism, and instability.

In recent decades, interdisciplinary efforts spanning chemistry, physics, biology, mathematics, technology, and biomedical sciences have driven the successful development of advanced drug delivery systems (ADDSs). These innovations enable the precise targeting of complex biological sites while ensuring optimal concentrations of bioactive compounds at the right time and for the appropriate duration. Such advancements undoubtedly refine the pharmacokinetic and/or pharmacodynamic profiles of encapsulated natural products. Additionally, patient compliance is enhanced, while safety is improved by administering lower doses, reducing drug exposure, and limiting distribution to non-target tissues, among other benefits. Nevertheless, the development of ADDSs continues to encounter challenges that require further investigation and remain a central focus of intense scientific inquiry.

The Pharmaceutics Special Issue, entitled “Advanced Drug Delivery Systems for Natural Products”, aims to present the latest advancements in this field. We invite all interested researchers to submit their innovative approaches (original research articles or comprehensive reviews), which will contribute to expanding knowledge in this rapidly developing area.

Dr. Velichka Andonova
Dr. Viliana Eduardova Gugleva
Dr. Stanila Stoeva
Guest Editors

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Keywords

  • natural products
  • advanced drug delivery systems
  • liposomes
  • niosomes
  • phytosomes
  • lipid nanoparticles
  • smart polymers
  • biodegradable nanoparticles
  • polymeric nanoparticles
  • drug carriers

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