Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Therapeutic Potential of Cannabinoid Receptors Type 1 and 2—Novel Insights for Enhancing the Chance of Clinical Success, 2nd Edition
edited by
submission deadline 25 Oct 2025 | Viewed by 91 | Submission Open
Keywords: endocannabinoid system (ECS); cannabinoid receptor type 1 (CB1R); cannabinoid receptor type 2 (CB2R); cannabinoids; ligand
(This special issue belongs to the Section Pharmacology)
Organochalcogen Derivatives in Medicinal Chemistry
edited by Agata Pacuła-Miszewska and
submission deadline 25 Oct 2025 | Viewed by 71 | Submission Open
Keywords: organochalcogens; modern organic synthesis; medicinal chemistry; biological activity
(This special issue belongs to the Section Medicinal Chemistry)
Natural Products and Their Modifications as Agents Used in the Fight Against Pathogens, 2nd Edition
edited by
submission deadline 27 Oct 2025 | 1 articles | Viewed by 436 | Submission Open
Keywords: plant extract; natural compounds; multidrug-resistant strains; intestinal microbiota; chemical modyfication; biotransformation
(This special issue belongs to the Section Natural Products)
Development of Copper-Based Drugs: Synthesis, Characterisation and Biological Activity submission deadline 28 Oct 2025 | 1 articles | Viewed by 2191 | Submission Open
Keywords: copper; copper coordination compounds; biologically active agents; radiopharmaceuticals; drug development; drug design
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Prostate Cancer Therapeutics
edited by
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1479 | Submission Open
Keywords: prostate cancer; androgen deprivation therapy (ADT); castration-resistant prostate cancer (CRPC); androgen receptor signaling inhibitors; PARP inhibitors; ionizing radiation therapy; radiopharmaceuticals; immunotherapy; biomarkers; personalized medicine; therapeutic resistance; targeted therapy; combination therapy; hormone-sensitive prostate cancer (HSPC); next-generation therapeutics; translational oncology
(This special issue belongs to the Section Pharmacology)
Precision Oncology: Targeting Molecular Subtypes in Cancer Therapy
edited by and Jiro Ogura
submission deadline 30 Oct 2025 | 1 articles | Viewed by 626 | Submission Open
Keywords: cancer chemotherapy; cancer genomic profiling test; next-generation sequencing; genetic variants; molecular targeted therapy; molecular tumor board; liquid biopsy
(This special issue belongs to the Section Pharmacology)
Advancements and Challenges of Intrapleural and Peritoneal Drug Delivery submission deadline 31 Oct 2025 | 2 articles | Viewed by 5478 | Submission Open
Keywords: peritoneal and pleural malignancies; intraperitoneal and pleural drug delivery; peritoneal dialyses; peritonitis; pleuritis; hyperthermic intraperitoneal chemotherapy (HIPEC); surface applications; colorectal cancer; ovarian cancer
(This special issue belongs to the Section Pharmaceutical Technology)
Drug Discovery and Development for Parasitic Diseases
edited by
submission deadline 31 Oct 2025 | 5 articles | Viewed by 5289 | Submission Open
Keywords: parasitic diseases; biological activity; synthesis; pharmacology; medicine; chemistry; target
(This special issue belongs to the Section Medicinal Chemistry)
Purinergic Signaling in Cancer Therapy: From Mechanisms to Targeting Strategies submission deadline 31 Oct 2025 | 1 articles | Viewed by 1635 | Submission Open
Keywords: purinergic signaling; cancer; ATP; adenosine; purinergic receptors; immune modulation; tumor progression; therapeutic potential
(This special issue belongs to the Section Pharmacology)
Pharmaceuticals for Inflammatory Bowel Disease (IBD)
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1594 | Submission Open
Keywords: inflammatory bowel disease; IBD symptoms; IBD pathogenesis; IBD treatments
(This special issue belongs to the Section Pharmacology)
Emerging Therapeutics for the Prevention of Chemotherapy-Induced Cardiotoxicity: Advances and Future Perspectives submission deadline 31 Oct 2025 | 1 articles | Viewed by 1139 | Submission Open
Keywords: cardio-oncology; chemotherapy-induced cardiotoxicity; cardioprotective agents; biomarkers; heart failure prevention; precision medicine; pharmacological innovation; molecular targets; cancer survivorship; multidisciplinary care
(This special issue belongs to the Section Pharmacology)
Classical and Novel Technology in the Extraction and Analysis of Active Ingredients from Natural Products for Effective Pre-Clinical Use submission deadline 31 Oct 2025 | 1 articles | Viewed by 662 | Submission Open
Keywords: classical extraction; nanotechnology; active ingredients; nanozymes; nanocomposites; molecularly imprinted polymer; magnetic nanoparticles; MOFs; natural products; pre-clinical studies
(This special issue belongs to the Section Natural Products)
Advances in Medicinal Chemistry: 2nd Edition
edited by
submission deadline 31 Oct 2025 | 1 articles | Viewed by 619 | Submission Open
Keywords: drug discovery; novel drug targets; drug discovery; drug design and development; synthetic methods for drugs; analytical methodologies; in silico screening; structure and ligand-based drug design; structure– activity relationships (SAR); drug metabolism
(This special issue belongs to the Section Medicinal Chemistry)
Production, Development and Theranostic Applications of Radiopharmaceuticals for Nuclear Medicine
edited by Vlad Ghizdovat, Cipriana Stefanescu and Cécile Philippe
submission deadline 31 Oct 2025 | Viewed by 530 | Submission Open
Keywords: theranostic; radiopharmaceuticals; nuclear medicine; alpha-emitting radioisotopes; beta-emitting radioisotopes; gamma-emitting radioisotopes
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Identification and Extraction of Bioactive Compounds from Marine Life
edited by and Wilfred T. Mabusela
submission deadline 31 Oct 2025 | Viewed by 173 | Submission Open
Keywords: natural products; marine life; bioactive compounds; cancer; antimicrobials
(This special issue belongs to the Section Natural Products)
Essential Oil-Based Nanoemulsions
edited by Pinho Fernandes Fernandes
submission deadline 31 Oct 2025 | Viewed by 92 | Submission Open
Keywords: volatile oil; monoterpene; sesquiterpene; phenylpropanoid; dynamic light scattering
(This special issue belongs to the Section Pharmaceutical Technology)
Drug-Induced and Herbal Hepatotoxicity and Methods of Its Prevention: 2nd Edition submission deadline 31 Oct 2025 | Viewed by 88 | Submission Open
Keywords: drug-induced hepatotoxicity; herbal hepatotoxicity; hepatotoxic interactions; acute and chronic liver damage; pathomechanisms of liver injury; oxidative stress; inflammation; apoptosis and necrosis; fibrosis
(This special issue belongs to the Section Pharmacology)
Advances in the Chemical-Biological Knowledge of Essential Oils
edited by and Emma Cocco
submission deadline 10 Nov 2025 | 3 articles | Viewed by 4719 | Submission Open
Keywords: essential oils (EOs); volatile compounds; chemical composition; biological activity; traditional botanical knowledge
(This special issue belongs to the Section Natural Products)
Therapeutic Potential of Chalcone Derivatives submission deadline 10 Nov 2025 | 2 articles | Viewed by 3527 | Submission Open
Keywords: chalcones; pharmacological potential; structural characterization; bioactivity; in silico study; cytotoxicity; quantum chemical calculations; ecapsulation
(This special issue belongs to the Section Pharmacology)
The 20th Anniversary of Pharmaceuticals—Ethnopharmacology in Latin America submission deadline 15 Nov 2025 | 7 articles | Viewed by 11156 | Submission Open
Keywords: Latin America; preclinical; clinical; ethnobotany; pharmacology; chemical standardization; herbal products
(This special issue belongs to the Section Natural Products)
Recent Advances in Stomach and Intestinal Drug Delivery Systems
edited by
submission deadline 15 Nov 2025 | Viewed by 434 | Submission Open
Keywords: stomach delivery; intestinal delivery; meso– nanostructured carriers; micro– nanoparticles/capsules; permeability enhancement; stability; absorption enhancement; gut delivery
(This special issue belongs to the Section Pharmaceutical Technology)
Pharmacotherapy of Prostate Cancer
edited by
submission deadline 15 Nov 2025 | Viewed by 73 | Submission Open
Keywords: prostate cancer; clinical; treatment; prostate cancer imaging; targeted therapy; immunotherapy
(This special issue belongs to the Section Pharmacology)
Optimized or Precise Pharmacological Treatment of Bipolar Disorder
edited by
submission deadline 20 Nov 2025 | 5 articles | Viewed by 24843 | Submission Open
(This special issue belongs to the Section Pharmacology)
Protein and Peptide-Based Drug Delivery
edited by Hoda M. Eltaher
submission deadline 20 Nov 2025 | 2 articles | Viewed by 3378 | Submission Open
Keywords: proteolytic degradation; chemical stability; immunogenicity; oral bioavailability; scalability; off- target; effects; bioconjugation; peptide engineering; biodegradable polymers; regulatory and clinical considerations
(This special issue belongs to the Section Biopharmaceuticals)
Pharmacotherapy of Diseases Affecting Urinary Tract
edited by
submission deadline 20 Nov 2025 | 2 articles | Viewed by 2010 | Submission Open
Keywords: natural products; plant extracts and isolated compounds; synthesized compounds; modified compounds; drug repositioning; kidney stone; urolithiasis; diuresis; urinary tract; urinary tract infection; cystitis; urethritis; nephritis; renal hypertension; diabetic nephropathy; nephrotoxicity; renal failure; urinary incontinence; overactive bladder; prostatitis; prostatic hyperplasia
(This special issue belongs to the Section Pharmacology)
Antiplatelet Therapy in Inflammatory Diseases submission deadline 20 Nov 2025 | Viewed by 213 | Submission Open
Keywords: atherosclerotic diseases; inflammatory diseases; antiplatelet therapy; platelet inhibition
(This special issue belongs to the Section Biopharmaceuticals)
Discovery of Novel Antidepressants and Anxiolytics
edited by James Oluwagbamigbe Fajemiroye and Gunnar P. H. Dietz
submission deadline 25 Nov 2025 | 6 articles | Viewed by 11902 | Submission Open
Keywords: biomarkers; depression; anxiety; anxiolytics; antidepressants; preclinical or clinical overview; experimental data; adverse effects; pharmacotherapy options; novel drugs
(This special issue belongs to the Section Pharmacology)
Multitargeted Compounds: A Promising Approach in Medicinal Chemistry
edited by Abdallah Hamze
submission deadline 25 Nov 2025 | 4 articles | Viewed by 10817 | Submission Open
Keywords: multitargeted compounds; medicinal chemistry; rational design; drug discovery; synergistic effects; emerging technologies; therapeutic applications; dual compounds
(This special issue belongs to the Section Medicinal Chemistry)
Peptide Synthesis and Drug Development: Exploring Progress and Potential
edited by , Da’san M.M. Jaradat and Vera D'Aloisio
submission deadline 25 Nov 2025 | 3 articles | Viewed by 5954 | Submission Open
Keywords: peptides; enzymatic degradation; drug discovery; formulation; draggability
(This special issue belongs to the Section Biopharmaceuticals)
Pediatric Drug Therapy: Safety, Efficacy, and Personalized Medicine submission deadline 25 Nov 2025 | 4 articles | Viewed by 5438 | Submission Open
Keywords: pediatric pharmacotherapy; drug safety in children; pediatric drug efficacy; personalized medicine in pediatrics; pediatric pharmacokinetics; pediatric pharmacodynamics; pharmacogenomics in children; pediatric clinical trials; pediatric dosing strategies; pediatric drug formulations
(This special issue belongs to the Section Pharmacology)
Molecular Mechanisms and Treatment of Brain Cancer: Recent Advances and Future Trends
edited by
submission deadline 25 Nov 2025 | 3 articles | Viewed by 4610 | Submission Open
Keywords: brain cancer; molecular mechanism; treatment; diagnosis; in vitro; in vivo; models
(This special issue belongs to the Section Pharmacology)
Biosimilars Development Strategies
edited by and Sesselja S. Ómarsdóttir
submission deadline 25 Nov 2025 | 3 articles | Viewed by 3383 | Submission Open
Keywords: biosimilars; generic medicines; drug development; biosimilar development
(This special issue belongs to the Section Medicinal Chemistry)
Novel Therapeutic Strategies for Alzheimer’s Disease Treatment
edited by
submission deadline 25 Nov 2025 | 1 articles | Viewed by 3323 | Submission Open
Keywords: Sporadic; late-onset Alzheimer’ s disease (LOAD); neurodegenerative diseases
(This special issue belongs to the Section Pharmacology)
Nanotechnology in Biomedical Applications submission deadline 25 Nov 2025 | 5 articles | Viewed by 3161 | Submission Open
Keywords: nanotechnology; nanobiotechnology; biomedical applications; drug delivery; nanobiosensors; targeted therapy; diagnostics; nanomaterials; therapeutics; theranostics
(This special issue belongs to the Section Pharmaceutical Technology)
New Development in Pharmacotherapy of Kidney Diseases
edited by Chihchao Yang
submission deadline 25 Nov 2025 | 3 articles | Viewed by 1911 | Submission Open
Keywords: chronic kidney disease (CKD); acute kidney injury (AKI); pharmacotherapy; cardiovascular protection; kidney protection; bone health; endocrine function; gut health; metabolism; neuromuscular function; nutrition; symptom management; sodium-glucose cotransporter-2 (SGLT-2) inhibitors; glucagon-like peptide-1 (GLP-1) receptor agonists; non-steroidal mineralocorticoid receptor antagonists (MRA); endothelin receptor antagonists; anemia management; electrolyte abnormalities; dialysis; nephrotoxicity; drug interactions; uremic toxin; clinical trials; innovative therapies; protein-energy wasting; chronic kidney disease and bone mineral disease; inflammation; oxidation; diabetes; hypertension; obesity; hyperlipidemia; pruritus; osteoporosis; fracture; sarcopenia; protein-energy wasting
(This special issue belongs to the Section Pharmacology)
Medicinal Chemistry of Metal Complexes: Design, Synthesis and Evaluation submission deadline 25 Nov 2025 | 1 articles | Viewed by 1677 | Submission Open
Keywords: metal complexes; medicinal chemistry; bioinorganic chemistry; coordination chemistry; organometallics; metal-based drugs; biological activity; toxicology; biomedical application; drug delivery
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in the Discovery and Development of Drugs for Civilization Diseases, 2nd Edition submission deadline 25 Nov 2025 | 3 articles | Viewed by 1260 | Submission Open
Keywords: anticancer drugs; anticancer treatment; anticoagulants; atherosclerosis; cardiovascular disease; civilization diseases; diabetes mellitus; drug development; in silico research; medication form/drug dosage form; molecular descriptors; molecular docking; molecular dynamics; molecular modeling; neoplastic disease; obesity; QSAR; radiopharmaceuticals; synthesis of bioactive compounds; type 2 diabetes
(This special issue belongs to the Section Medicinal Chemistry)
The Therapeutic Potential of Cannabidiol submission deadline 25 Nov 2025 | 1 articles | Viewed by 1018 | Submission Open
Keywords: cannabidiol; endocannabinoid system; pain; anti-inflammatory agents; muscle spasticity; pain management; chronic pain
(This special issue belongs to the Section Natural Products)
Innovations in Therapeutic Strategies for Retinal and Neurodegenerative Diseases
edited by and Won-Kyu Ju
submission deadline 25 Nov 2025 | 1 articles | Viewed by 955 | Submission Open
Keywords: glaucoma; Alzheimer's diseases; retinal disease; neuroprotection; neuroinflammation
(This special issue belongs to the Section Pharmacology)
Pharmaceutical Approaches to Orofacial Pain and Chronic Pain Conditions
edited by
submission deadline 25 Nov 2025 | 1 articles | Viewed by 838 | Submission Open
Keywords: chronic orofacial pain; pharmaceutical approach; myofascial orofacial pain; temporomandibular joint pain; neurovascular orofacial pain; idiopathic orofacial pain; burning mouth syndrome; persistent idiopathic facial pain; persistent idiopathic dentoalveolar pain; tricyclic antidepressants; serotonin reuptake inhibitors; anticonvulsants
(This special issue belongs to the Section Pharmacology)
Antimicrobial Therapies Affect the Microbial Ecosystems Within Our Body: The Urinary Microbiome and Urolithiasis submission deadline 25 Nov 2025 | 1 articles | Viewed by 613 | Submission Open
Keywords: antibiotics; antimicrobials; resistance; microbiome; urolithiasis; biofilms; infections; pathogens; pharmacotherapy; inflammation
(This special issue belongs to the Section Pharmacology)
Pharmacology and Toxicology of Opioids, 2nd Edition
edited by , Joana Barbosa and
submission deadline 25 Nov 2025 | Viewed by 589 | Submission Open
Keywords: opioid toxicity; opioid pharmacodynamics; opioid pharmacokinetics; opioid pharmacogenetics; prescription opioids; toxicity assays; in vivo; in vitro; abuse; dependence
(This special issue belongs to the Section Pharmacology)
Cutting-Edge Biotechnologies and Applications of Natural Products in Drug R&D and Disease Treatment
edited by
submission deadline 25 Nov 2025 | 1 articles | Viewed by 526 | Submission Open
Keywords: natural products; bioactive compounds; natural product drug discovery and drug design; natural drug formulation; metabolic engineering for bioactive compounds; natural therapeutic agents; nanoformulations of natural compounds; synthetic biology for natural product biosynthesis; genome editing and creation of novel bioactive compounds
(This special issue belongs to the Section Natural Products)
New Findings in Pharmacogenomics of Neuropsychiatric Disorders submission deadline 25 Nov 2025 | Viewed by 414 | Submission Open
Keywords: pharmacogenomics; genome informatics; advanced DNA-sequencing technologies; bioinformatics of pharmacogenomics; diagnostic approaches in the pharmacogenomics of neuropsychiatric disorders
(This special issue belongs to the Section Pharmacology)
Research on Diagnosis, Treatment and Related Microbiota in Gastrointestinal Diseases
edited by and Brigida Barberio
submission deadline 25 Nov 2025 | Viewed by 272 | Submission Open
Keywords: gut microbiota; inflammatory bowel disease; eosinophilic esophagitis; primary sclerosing cholangitis; metabolic-associated steatotic liver disease; immune checkpoint inhibitor colitis; dysbiosis; prebiotics; probiotics
(This special issue belongs to the Section Medicinal Chemistry)
The Development and Application of Broad-Spectrum Antiviral Drugs
edited by Chieh-Wen Lo
submission deadline 25 Nov 2025 | Viewed by 247 | Submission Open
Keywords: broad-spectrum antiviral; direct-acting antiviral; host-targeted antiviral; emerging viruses; pandemic preparedness
(This special issue belongs to the Section Medicinal Chemistry)
Anticancer Compounds in Medicinal Plants—4th Edition submission deadline 25 Nov 2025 | Viewed by 214 | Submission Open
Keywords: natural products; phytochemicals; cancer; secondary metabolites; medicinal plants
(This special issue belongs to the Section Natural Products)
Application of Nanotechnology in Drug Delivery
edited by Camila Batista Da Silva and
submission deadline 25 Nov 2025 | Viewed by 174 | Submission Open
Keywords: drug discovery; drug combinations; nanotechnology; drug liberation
(This special issue belongs to the Section Pharmaceutical Technology)
Advances in Hydrazone Compounds with Anticancer Activity submission deadline 25 Nov 2025 | Viewed by 143 | Submission Open
Keywords: hydrazones; lipophilicity; logP; anticancer activity; selectivity
(This special issue belongs to the Section Medicinal Chemistry)
Pharmacological Activities of Flavonoids and Their Analogues, Third Edition submission deadline 25 Nov 2025 | Viewed by 142 | Submission Open
Keywords: natural products; polyphenols; flavonoids; medicinal chemistry; traditional medicine; flavonoids isolation; flavonoids identification; flavonoids pharmacology; flavonoids as prodrugs; in vivo; in vitro; and in silico studies; molecular modeling studies
(This special issue belongs to the Section Natural Products)
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