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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Antidepressant Drug

edited by

Paulina Misztak

submission deadline 15 Nov 2024 | 2 articles | Viewed by 3223 | Submission Open

Keywords: antidepressant; molecular mechanism of drugs; new targets for depression treatment; depression; MDD; animal models of depression; nutrition in depression; small molecules

(This special issue belongs to the Section Pharmacology)

Therapeutic Potential of Vitamin D in Depressive Disorder and Anxiety Disorders

edited by

Ana Lúcia Severo Rodrigues

submission deadline 15 Nov 2024 | 1 articles | Viewed by 1303 | Submission Open

Keywords: antidepressant; anxiety; cholecalcipherol; depression; major depressive disorder; vitamin D

(This special issue belongs to the Section Medicinal Chemistry)

Current Advances in Therapeutic Potential of Sigma Receptor Ligands

edited by Maria Dichiara and

Emanuele Amata

submission deadline 15 Nov 2024 | Viewed by 121 | Submission Open

Keywords: sigma-1 receptor; sigma-2 receptor; TMEM97; cancer; neurodegeneration; neuroprotection; pain; CNS disorders; SAR

(This special issue belongs to the Section Medicinal Chemistry)

Neuropharmacology of Plant Extracts and Their Active Compounds

edited by

Angel Josabad Alonso-Castro

submission deadline 20 Nov 2024 | 6 articles | Viewed by 10736 | Submission Open

Keywords: medicinal plant; mental disorder; preclinical; clinical

(This special issue belongs to the Section Natural Products)

Pharmacological Properties and Therapeutic Potential of Honey Bee Products

edited by

Michał Miłek

and Dana Marcinčáková

submission deadline 20 Nov 2024 | 8 articles | Viewed by 8497 | Submission Open

Keywords: honey; propolis; bee pollen; bee bread; royal jelly; anticancer; anti-inflammatory; antimicrobial; mechanism of action; pharmacological properties

(This special issue belongs to the Section Natural Products)

A Commemorative Special Issue in Honor of Prof. Jolanta Saczko: Pharmaceutical Science in Electrochemotherapy

edited by

Nina Rembiałkowska

submission deadline 20 Nov 2024 | 5 articles | Viewed by 7774 | Submission Open

Keywords: electrochemotherapy; cell membrane permeability; pulsed electric; field anticancer compounds delivery; natural compounds; bioactive compounds; plant extract; cytotoxicity; anticancer activity; antiproliferative activity

(This special issue belongs to the Section Medicinal Chemistry)

Anti-obesity and Anti-aging Natural Products

edited by

Rosario Mare

and

Vincenzo Musolino

submission deadline 20 Nov 2024 | 7 articles | Viewed by 6827 | Submission Open

Keywords: anti-obesity; anti-aging; natural products; herbal remedies; antioxidants; weight management; aging prevention; phytochemicals; botanical extracts; metabolic health; healthy aging

(This special issue belongs to the Section Natural Products)

Pharmacology and Toxicology of Opioids

edited by

Juliana Faria

, Joana Barbosa and

Ricardo Dinis-Oliveira

submission deadline 20 Nov 2024 | 2 articles | Viewed by 3741 | Submission Open

Keywords: opioid toxicity; opioid pharmacodynamics; opioid pharmacokinetics; opioid pharmacogenetics; prescription opioids; toxicity assays; in vivo; in vitro; abuse; dependence

(This special issue belongs to the Section Pharmacology)

Drug Candidates for the Treatment of Obesity, 2nd Edition

edited by

Maria Isabel Cardoso Alonso-Vale

and

Monica Marques Telles

submission deadline 20 Nov 2024 | 3 articles | Viewed by 3118 | Submission Open

Keywords: obesity; appetite supressors; nutraceuticals; plant extracts; lipid metabolism; high-fat diet; adipogenesis

(This special issue belongs to the Section Medicinal Chemistry)

New Therapeutic Opportunities for Epigenetic Drugs

edited by Sebastiano Giallongo

submission deadline 20 Nov 2024 | 1 articles | Viewed by 1215 | Submission Open

Keywords: epigenetics; aging; personalized medicine; tumor microenvironment; DNA methyltransferase; histone acetyltransferase; histone deacetylases; histone variants; epigenetics-metabolism axis

(This special issue belongs to the Section Biopharmaceuticals)

Advances in Pharmacotherapy of Neuropathic Pain

edited by

Marucia Chacur

submission deadline 20 Nov 2024 | 1 articles | Viewed by 1067 | Submission Open

Keywords: analgesic; inflammation; neurotransmitters; neuroplasticity; targeted therapies; neurogenic pain; opioids; cannabinoids

(This special issue belongs to the Section Pharmacology)

Advances in Antiparasitic Natural Products

edited by Lizandra Guidi Magalhães

submission deadline 20 Nov 2024 | 1 articles | Viewed by 698 | Submission Open

Keywords: parasites; antiparasitics; natural products

(This special issue belongs to the Section Natural Products)

Peptide Synthesis and Drug Development: Exploring Progress and Potential

edited by

Othman Al Musaimi

, Da’san M.M. Jaradat and Vera D'Aloisio

submission deadline 20 Nov 2024 | Viewed by 354 | Submission Open

Keywords: peptides; enzymatic degradation; drug discovery; formulation; draggability

(This special issue belongs to the Section Biopharmaceuticals)

Recent Advances in Antimicrobial Nano-Drug Delivery Systems

edited by

Luís Alexandre Muehlmann

submission deadline 20 Nov 2024 | Viewed by 237 | Submission Open

Keywords: infectious diseases; antimicrobial resistance; antibiotics; antifungal drugs; nanostructures; pathogen adaptation; nanomedicine

(This special issue belongs to the Section Pharmaceutical Technology)

Inhibitors of κB Kinase (IKK) and Nuclear Factor Kappa-B (NF-κB): Attractive Drug Targets

edited by Guozhou Xu

submission deadline 20 Nov 2024 | Viewed by 228 | Submission Open

Keywords: IkB kinase; kinase activation; protein– protein interaction; ATP-competitive small-molecule kinase inhibitor; inflammatory disease; autoimmune disease

(This special issue belongs to the Section Medicinal Chemistry)

Neurodegenerative Disorders: Computer – Aided Drug Design, Еxperimental Аpproaches and Mechanisms

edited by

Mariyana Atanasova

and

Rumyana Simeonova

submission deadline 20 Nov 2024 | Viewed by 211 | Submission Open

Keywords: neurodegenerative disorders; drug design; molecular docking; Alzheimer’ s disease; pharmacological mechanism

Psychedelics: A New Drug Candidate for Treating Mental Illness

edited by

Raphaël Serreau

and

Sabine Berteina-Raboin

submission deadline 20 Nov 2024 | Viewed by 116 | Submission Open

Keywords: psychedelics drugs; psilocybin; psilocin; pharmacokinetic; pharmacodynamic; new drug candidate; mental diseases

(This special issue belongs to the Section Pharmacology)

Molecular Mechanisms and Therapeutic Resistance in Cancer: Insights from Transcriptional Regulation and Immune Modulation

edited by Hyunmin Kim

submission deadline 20 Nov 2024 | Viewed by 90 | Submission Open

Keywords: cancer; therapeutic resistance; transcriptional dysregulation; bioinformatics; artificial intelligence; machine learning; cancer therapy; resistance mechanisms; cancer treatment; gene regulation; multi-omics multi-modal single cell; cancer cell heterogeneity

(This special issue belongs to the Section Pharmacology)

Plant-Derived Nanotherapeutics and Nanocarriers: Recent Progress and Future Directions

edited by

Estefânia V.R. Campos

and

Jhones Luiz De Oliveira

submission deadline 22 Nov 2024 | 7 articles | Viewed by 17364 | Submission Open

Keywords: plant-based nanomaterials; green nanomaterials; drug delivery; natural nanotherapeutics; pharmaceutical nanoformulations; biogenic synthesis; phytonanotechnology

(This special issue belongs to the Section Pharmaceutical Technology)

Interaction between Nanoparticles and Antibiotics：Against Antimicrobial Resistance

edited by

Isabella Macário Ferro Cavalcanti

and Maria Carolina Accioly Brelaz de Castro

submission deadline 22 Nov 2024 | 3 articles | Viewed by 5609 | Submission Open

Keywords: microorganisms; resistance; pharmaceutical research; nanotechnology

Orodispersible Tablets: New Advances in Preparation Technologies

edited by

Witold Brniak

and

Aleksander Mendyk

submission deadline 22 Nov 2024 | 1 articles | Viewed by 994 | Submission Open

Keywords: orodispersible tablets; orally disintegrating tablets; superdisintegrants; co-processed excipients; direct compression; 3D printing

(This special issue belongs to the Section Pharmaceutical Technology)

Design, Synthesis, Evaluation and Biopharmaceutical Uses of Imatinib, Nilotinib and Their Analogues

edited by

Alexandros D. Tselepis

, Dimitrios Alivertis and Pinelopi Voulgari

submission deadline 22 Nov 2024 | Viewed by 444 | Submission Open

Keywords: cancer; inhibitors; Imatinib; Nilotinib; protein kinases; target therapy

(This special issue belongs to the Section Medicinal Chemistry)

Pharmacotherapy of Inflammatory Bowel Disease

edited by

Wolfgang Kruis

submission deadline 23 Nov 2024 | Viewed by 300 | Submission Open

Keywords: Treatment of Crohn's Disease; treatment of ulcerative Colitis; mesalazine for ulcerative colitis; mesalazine for Crohn's Disease; antibody strategies in IBD; small molecules for IBD; conservative managenment of Crohn's fistula; therapy for extraintestinal manifestations; new endpoints for treatment

(This special issue belongs to the Section Pharmacology)

New Findings in Pharmacogenomics of Neuropsychiatric Disorders

edited by

Alireza Tafazoli

and

Mandana Hasanzad

submission deadline 23 Nov 2024 | Viewed by 160 | Submission Open

Keywords: pharmacogenomics; genome informatics; advanced DNA-sequencing technologies; bioinformatics of pharmacogenomics; diagnostic approaches in the pharmacogenomics of neuropsychiatric disorders

(This special issue belongs to the Section Pharmacology)

Computer-Aided Drug Design and Drug Discovery

edited by

Dragos Mihai

and

George Mihai Nitulescu

submission deadline 25 Nov 2024 | 18 articles | Viewed by 37541 | Submission Open

Keywords: chemoinformatics; bioinformatics; molecular modeling; virtual screening; molecular docking; quantitative structure– activity relationship (QSAR); pharmacophore modeling; target identification; repurposing; ADME-T prediction

(This special issue belongs to the Section Medicinal Chemistry)

20th Anniversary of Pharmaceuticals—Therapeutic Mechanisms of Nature Products against Insulin Resistance 2024

edited by

Anne-Dominique Lajoix

and

Didier Tousch

submission deadline 25 Nov 2024 | 3 articles | Viewed by 8696 | Submission Open

Keywords: insulin resistance; signaling pathways; liver; skeletal muscle; adipose tissues; traditional medicine; plants; fungus; algae; food ingredients

(This special issue belongs to the Section Natural Products)

NeuroImmunoEndocrinology

edited by

Lenin Pavon

Daniel Ortuño-Sahagún

Gilberto Perez-Sanchez

and Oscar Adelmo Bottasso

submission deadline 25 Nov 2024 | 4 articles | Viewed by 7944 | Submission Open

Keywords: cytokines; neurotransmitters; hormones; infections; antibiotics; antidepressants; antipsychotics; drugs; stress; depression; schizophrenia; immunomodulation

(This special issue belongs to the Section Pharmacology)

Pharmacological Insight into NMDA Receptor Antagonists

edited by

Franck Jean Talmont

submission deadline 25 Nov 2024 | 3 articles | Viewed by 4469 | Submission Open

Keywords: ionotropic receptors; NMDA receptors; antidepressants; radiotracers; neurodegenerative diseases

(This special issue belongs to the Section Pharmacology)

Unraveling the Multifaceted Role of Polyphenols in Health Issues

edited by

Hélder Oliveira

and

Ana Fernandes

submission deadline 25 Nov 2024 | 3 articles | Viewed by 4017 | Submission Open

Keywords: polyphenols; bioactivity; bioavailability; functional foods; polysaccharides

(This special issue belongs to the Section Natural Products)

Polymorphs, Salts, Cocrystals and Cationic Lipid Nanoparticle Complexes in Drug Delivery

edited by

Stephen Robert Byrn

submission deadline 25 Nov 2024 | 3 articles | Viewed by 3733 | Submission Open

(This special issue belongs to the Section Pharmaceutical Technology)

Advances in Drug Analysis and Drug Development

edited by

Daniela Amidžić Klarić

and Ana Mornar

submission deadline 25 Nov 2024 | 3 articles | Viewed by 3525 | Submission Open

Keywords: analytical methodology; chromatographic techniques; spectrometric techniques; thermal analysis techniques; sample preparation; drug stability; compatibility study; bioavailability studies; therapeutic drug monitoring; quality by design in pharmaceutical analysis

(This special issue belongs to the Section Pharmaceutical Technology)

Pharmacological Activities of Flavonoids and Their Analogues 2024

edited by

Fernando Calzada

and

Miguel Valdes

submission deadline 25 Nov 2024 | 1 articles | Viewed by 3492 | Submission Open

Keywords: natural products; polyphenols; flavonoids; medicinal chemistry; traditional medicine; flavonoid isolation; flavonoid identification; flavonoid pharmacology; flavonoids as prodrugs; in vivo; in vitro and in silico studies; molecular modeling studies

(This special issue belongs to the Section Natural Products)

Photosensitizers and Drug Delivery Systems for Photodynamic Therapy

edited by

Céline Frochot

submission deadline 25 Nov 2024 | 3 articles | Viewed by 3207 | Submission Open

Keywords: photodynamic therapy; photosensitizers; nanoparticles; photo diagnosis; targeting; antimicrobial; X-rays excitation; two-photon and up-conversion; Cherenkov; hypoxia

(This special issue belongs to the Section Pharmaceutical Technology)

Design and Synthesis of Small Molecule Kinase Inhibitors

edited by

Camilla Pecoraro

and

Daniela Carbone

submission deadline 25 Nov 2024 | 2 articles | Viewed by 3147 | Submission Open

Keywords: protein kinases; cancer; small molecule kinase inhibitors; heterocyclic compounds; cancer resistance; targeted therapy; cancer-altered pathway; genetic mutations; FDA-approved kinase inhibitors; kinase inhibitors combinations

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Mass Spectrometry Metrology in Pharmaceutical Sciences

edited by Andrew P. Bowman and Rob J. Vreeken

submission deadline 25 Nov 2024 | 3 articles | Viewed by 3110 | Submission Open

Keywords: analytical standards; calibration; quality control; reference materials; validation; impurities; stability; traceability; analytical methods; drug analysis

(This special issue belongs to the Section Pharmacology)

Dopamine and Serotonin Receptors: Selective or Multitarget Ligands for the Treatment of Central Nervous System Diseases

edited by

Fabio Del Bello

and Wilma Quaglia

submission deadline 25 Nov 2024 | 2 articles | Viewed by 2686 | Submission Open

Keywords: dopamine and serotonin neurotransmission; selective dopamine receptor ligands; selective serotonin receptor ligands; multitarget agents; central nervous system pathologies; psychiatric disorders; neurodegenerative diseases

(This special issue belongs to the Section Pharmacology)

Therapeutic Potential of Natural Products in Urolithiasis

edited by

Priscila de Souza

submission deadline 25 Nov 2024 | 2 articles | Viewed by 1984 | Submission Open

Keywords: natural products; plant extracts; isolated compounds from medicinal plants; kidney stone; nephrolithiasis; urinary tract; hypertension; diabetes; pain relievers

(This special issue belongs to the Section Natural Products)

Pharmacotherapy for Retinopathy

edited by Eric Shrier

submission deadline 25 Nov 2024 | 1 articles | Viewed by 1932 | Submission Open

Keywords: retinopathy of prematurity; ROP; anti-VEGF; HIF; pathologic neovascularization; OIR

(This special issue belongs to the Section Pharmacology)

Solubilization and Controlled Release Strategy of Poorly Water-Soluble Drugs 2024

edited by

María Ángeles Peña Fernández

submission deadline 25 Nov 2024 | 1 articles | Viewed by 1697 | Submission Open

Keywords: drug formulation; solubilization; controlled release systems; solubility; poor water-soluble drugs

(This special issue belongs to the Section Pharmaceutical Technology)

Amyloid Composition and Structure-Based Development of Therapeutic and Diagnostic Agents

edited by Emily B. Martin and Jonathan S. Wall

submission deadline 25 Nov 2024 | 2 articles | Viewed by 1618 | Submission Open

(This special issue belongs to the Section Medicinal Chemistry)

Discovery of Natural Products as Potential Antidiabetic Agents

edited by

Fernando Calzada

and

Miguel Valdes

submission deadline 25 Nov 2024 | 1 articles | Viewed by 1266 | Submission Open

Keywords: diabetes mellitus; diabetes complications; glucosidase inhibitors; antidiabetic agents; molecular mechanism; new drug development; pharmacology; molecular docking assays

(This special issue belongs to the Section Medicinal Chemistry)

In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research: New Advances

edited by Haitao Wu and

Noriko Sato

submission deadline 25 Nov 2024 | 1 articles | Viewed by 1191 | Submission Open

Keywords: in vivo nuclear imaging; biomarker imaging; molecular imaging; PET; SPECT; pharmacokinetics; personalized medicine; drug development; molecular pathway

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Smooth Muscle and Endothelial Cells as Pharmacological Targets for Acute Oxidative Stress

edited by Charles E. Norton

submission deadline 25 Nov 2024 | 1 articles | Viewed by 702 | Submission Open

Keywords: reactive oxygen species; oxidative stress; smooth muscle cells; endothelium; ischemia/reperfusion; stroke; myocardial infarction; traumatic brain injury

(This special issue belongs to the Section Pharmacology)

Exploring Biomarkers and Pharmacotherapies for Substance Use Disorders

edited by

Ani Gasparyan

Daniela Navarro

and

Jorge Manzanares

submission deadline 25 Nov 2024 | 1 articles | Viewed by 663 | Submission Open

(This special issue belongs to the Section Pharmacology)

Prodrugs: Design and Development

edited by

Viktor Reshetnikov

and

Chung Man Chin

submission deadline 25 Nov 2024 | Viewed by 493 | Submission Open

Keywords: prodrug; molecular modification; disease-specific activation; targeting; solubility and lipophilicity adjustment

(This special issue belongs to the Section Medicinal Chemistry)

Phytotherapeutic Applications in Colorectal Cancer (CRC) Management

edited by

Bence Raposa

and

John M. Macharia

submission deadline 25 Nov 2024 | Viewed by 267 | Submission Open

Keywords: colorectal; cancer; gene therapy; drug development; treatment; pathway

Drug Resistance Against Cancer Treatment

edited by

Hamidreza Montazeri Aliabadi

submission deadline 25 Nov 2024 | Viewed by 216 | Submission Open

Keywords: multidrug resistance (MDR); chemotherapy; P-glycoprotein (P-gp); ATP-binding cassette (ABC) transporters; molecularly targeted drugs; inherent resistance; acquired resistance; signaling pathways

(This special issue belongs to the Section Pharmacology)

Pharmacoepidemiology and Pharmacovigilance in Drug Therapy: New Issues, Challenges, and Applications

edited by Loreta Kubilienė

submission deadline 25 Nov 2024 | Viewed by 206 | Submission Open

Keywords: pharmacoepidemiology; pharmacovigilance; drug safety monitoring; regulatory practices; hospitalization; adverse drug events; drug safety; preventability

(This special issue belongs to the Section Pharmacology)

Ion Channels as Pharmacological Targets in Cancer

edited by

Concetta Altamura

Ilaria Saltarella

and

Ester Pagano

submission deadline 25 Nov 2024 | Viewed by 165 | Submission Open

Keywords: ion channels; cancer; cancer pharmacology; target therapies; personalized therapy; chemoresistance; oncology; channelopathies

(This special issue belongs to the Section Pharmacology)

Molecular Systems for the Delivery of Drugs and Contrast Agents

edited by

Luca Nardo

Angelo Maspero

and

Mauro Fasano

submission deadline 28 Nov 2024 | 9 articles | Viewed by 17200 | Submission Open

Keywords: biomarker-targeted drugs; contrast media for diagnostic imaging; drug delivery systems; photoactivated drugs and photoswitches; theranostics; liposomes; biomaterials-based drugs and drug shuttles (e.g.; DNA origami); biomimetic materials; nanoparticle applications to diagnostics and therapy; in silico drug design

(This special issue belongs to the Section Medicinal Chemistry)

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