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Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanomaterial Complexes Used in Cancer Therapies: Opportunities and Challenges

edited by

Ruizhuo Ouyang

submission deadline 25 Oct 2024 | Viewed by 107 | Submission Open

Keywords: smart nanomaterials; stimuli-responsive methods; multimodal imaging; drug delivery; cancer diagnosis and therapy; quantum dots; metallic nanoparticles; liposomes; dendrimers; micelles; polymeric nanoparticles

(This special issue belongs to the Section Pharmaceutical Technology)

Common Medications Used in Anesthesia

edited by Michał Jan Stasiowski

submission deadline 25 Oct 2024 | Viewed by 96 | Submission Open

Keywords: anesthesia; medications; pharmacology; perioperative care; drug interactions; patient safety; clinical practice; anesthesia management; drug development; patient outcomes

(This special issue belongs to the Section Medicinal Chemistry)

Natural Products in Diabetes Mellitus: 2nd Edition

edited by

Ana Angelica Feregrino-Perez

submission deadline 28 Oct 2024 | 2 articles | Viewed by 2586 | Submission Open

Keywords: natural products; hypoglycemia; phenolic compounds; diabetes mellitus; therapeutic; ROS

(This special issue belongs to the Section Natural Products)

Drug-Induced and Herbal Hepatotoxicity and Methods of Its Prevention

edited by

Anna Merwid-Ląd

and

Malgorzata Trocha

submission deadline 29 Oct 2024 | 7 articles | Viewed by 22507 | Submission Open

Keywords: drug-induced hepatotoxicity; herbal hepatotoxicity; acute and chronic liver damage; pathomechanisms of liver injury; oxidative stress; inflammation; apoptosis and necrosis; fibrosis

(This special issue belongs to the Section Pharmacology)

Design, Synthesis and Development of Novel Antiviral Agents

edited by

Antonio Lupia

submission deadline 30 Oct 2024 | 1 articles | Viewed by 1746 | Submission Open

Keywords: viruses; emerging viral diseases; infectious diseases; antiviral agents; small molecules; structure− activity relationship (SAR) studies; drug design (DD) and synthesis; computer-aided drug discovery (CADD); medicinal chemistry

(This special issue belongs to the Section Medicinal Chemistry)

Pharmacotherapy for Alzheimer’s Disease

edited by

Gabriela Dumitrița Stanciu

submission deadline 30 Oct 2024 | 1 articles | Viewed by 1534 | Submission Open

Keywords: Alzheimer’ s disease; pharmacotherapy; therapeutic editing tools; repurposing existing therapeutics; multi-target-directed ligands; preclinical studies; neurodegeneration; drug development; neuroprotection; cannabinoid-based pharmaceuticals; single-molecule drugs or whole-plant extracts of Cannabis sativa L.

(This special issue belongs to the Section Pharmacology)

Novel Therapeutic Targets and Approaches for the Treatment for Alzheimer's Disease

edited by

Marta Rusek

submission deadline 30 Oct 2024 | Viewed by 221 | Submission Open

Keywords: neurodegenerative diseases; Alzheimer's disease; molecular mechanism; drug delivery; drug development; potential therapeutic; advanced therapies; disease-modifying therapy; personalized therapy; clinical trials

(This special issue belongs to the Section Pharmacology)

Development of Copper-Based Drugs: Synthesis, Characterisation and Biological Activity

edited by

Anita Kornicka

and

Łukasz Balewski

submission deadline 30 Oct 2024 | Viewed by 196 | Submission Open

Keywords: copper; copper coordination compounds; biologically active agents; radiopharmaceuticals; drug development; drug design

(This special issue belongs to the Section Medicinal Chemistry)

The 20th Anniversary of Pharmaceuticals — Multi-Targeted Natural Products as Therapeutics

edited by

Elena Y. Enioutina

Kathleen M. Job

and

Catherine Sherwin

submission deadline 31 Oct 2024 | 18 articles | Viewed by 41188 | Submission Open

Keywords: natural products; medicinal herbs; marine products; animal products; bioactive compounds; multifactorial diseases; multi-targeting phytochemicals

(This special issue belongs to the Section Natural Products)

Structural and Other Proteomics Approaches in Drug Discovery

edited by

Marino F. A. Santos

and

Luís Passarinha

submission deadline 31 Oct 2024 | 4 articles | Viewed by 8035 | Submission Open

Keywords: artificial intelligence; bioinformatics; chemoproteomics; computational modelling; drug discovery; mass spectrometry; protein structure; proteomics structural; proteomics

(This special issue belongs to the Section Biopharmaceuticals)

Recent Advances and Future Approaches in Preventive and Therapeutic Effects of Vanadium Complexes

edited by

Monika Papież

and

Wirginia Krzyściak

submission deadline 31 Oct 2024 | 5 articles | Viewed by 7651 | Submission Open

Keywords: vanadium compounds; antidiabetic; insulinomimetic; antiobesity; anticancer; antimicrobial; cardioprotective; neuroprotective

(This special issue belongs to the Section Medicinal Chemistry)

Current Advances, Applications and Future Development of Transition Metal Complexes

edited by

Domenico Iacopetta

submission deadline 31 Oct 2024 | 2 articles | Viewed by 4193 | Submission Open

Keywords: transition metal complexes; synthesis; catalysis; ligands; biological activity; applications; enzyme inhibition

(This special issue belongs to the Section Medicinal Chemistry)

New and Emerging Treatment Strategies for Gastrointestinal Diseases

edited by

Daniele Maria-Ferreira

submission deadline 31 Oct 2024 | 1 articles | Viewed by 727 | Submission Open

Keywords: gastrointestinal diseases; gastrointestinal homeostasis; gastrointestinal injuries; gastrointestinal disturbances; dysbiosis; bile acid; inflammatory bowel diseases; diarrhea

(This special issue belongs to the Section Pharmacology)

Drug Delivery across the Blood–Brain Barrier

edited by

Touraj Ehtezazi

submission deadline 31 Oct 2024 | Viewed by 321 | Submission Open

Keywords: blood– brain barrier; drug delivery; brain diseases; neuroinflammation; remyelination

(This special issue belongs to the Section Pharmaceutical Technology)

Fluoroquinolones

edited by

Cecilia Bove

and

Nuno Manuel Xavier

submission deadline 31 Oct 2024 | Viewed by 234 | Submission Open

Keywords: fluoroquinolones; fluoroquinolone-associated disability; antibiotic safety; fluoroquinolone toxicity; antibiotic stewardship

(This special issue belongs to the Section Pharmacology)

DHA and EPA in Health and Disease

edited by

Anna Walczewska

Emilia Zgórzyńska

and

Katarzyna Wieczorek-Szukała

submission deadline 31 Oct 2024 | Viewed by 177 | Submission Open

Keywords: omega-3 polyunsaturated fatty acids; DHA; EPA; inflammation; oxidative stress; dietary supplements; cognitive decline; mental health; therapeutic strategies; cardiovascular diseases; hypertension; respiratory diseases

(This special issue belongs to the Section Pharmacology)

Polymers in Pharmaceutical Drug Delivery Systems

edited by

Clement Higginbotham

submission deadline 31 Oct 2024 | Viewed by 86 | Submission Open

Keywords: targeted drug delivery; polymer– drug conjugates; controlled release; stimuli-responsive polymers; pharmaceutical polymers; bioavailability; biodegradable polymers; hydrogels; drug encapsulation

(This special issue belongs to the Section Pharmaceutical Technology)

Drug Candidates for the Treatment of Oral Cancer and Oral Cancer Pain

edited by

Cara B. Gonzales

submission deadline 1 Nov 2024 | 8 articles | Viewed by 15500 | Submission Open

Keywords: oral cancer; oral cancer pain; drug discovery; natural compounds; immunotherapy; small molecule inhibitors; biomarkers

(This special issue belongs to the Section Medicinal Chemistry)

In Silico and In Vitro Screening of Small Molecule Inhibitors

edited by

Usama Ammar

and

Domiziana Masci

submission deadline 5 Nov 2024 | 2 articles | Viewed by 1450 | Submission Open

Keywords: early drug discovery; small molecule inhibitors (SMIs); new chemical entities (NCEs); drug repurposing; in silico screening; in vitro assays; targeted therapy; high-throughput screening; pharmacophore-based modeling; bioactive compounds; structure-based drug design

(This special issue belongs to the Section Medicinal Chemistry)

Drug Treatment of Cholangiocarcinoma

edited by

Abdullah Esmail

and Ala Abudayyeh

submission deadline 5 Nov 2024 | 1 articles | Viewed by 1369 | Submission Open

Keywords: cholangiocarcinoma; hepatic malignancy; intrahepatic (iCCA); perihilar (pCCA); gemcitabine; cisplatin; immunotherapy; durvalumab and distal (dCCA)

(This special issue belongs to the Section Pharmacology)

PET and SPECT Molecular Imaging in Drug Development

edited by

Hyun Soo Park

submission deadline 10 Nov 2024 | 1 articles | Viewed by 1379 | Submission Open

(This special issue belongs to the Section Radiopharmaceutical Sciences)

Pharmacotherapy of Liver Fibrosis and Hepatitis: Recent Advances

edited by

Ching-Lung Lai

submission deadline 10 Nov 2024 | 1 articles | Viewed by 966 | Submission Open

Keywords: treatment of HBV; HCV; SLD; detection and prevention of liver fibrosis and HCC

(This special issue belongs to the Section Pharmacology)

Recent Advances in the Synthesis and Evaluation of Beta-Lactamase Inhibitors

edited by Inês Bártolo

submission deadline 10 Nov 2024 | Viewed by 199 | Submission Open

Keywords: beta-lactamase inhibitors; rational drug design; combinatorial chemistry; antibiotic resistance

(This special issue belongs to the Section Medicinal Chemistry)

The 20th Anniversary of Pharmaceuticals—Nanoparticle Interactions with Cells

edited by

Dimitris Tsiourvas

submission deadline 10 Nov 2024 | Viewed by 135 | Submission Open

Keywords: cellular interactions; cell-membrane penetration; cell internalization; cellular uptake; endocytosis; biomembranes; computational modeling

(This special issue belongs to the Section Pharmaceutical Technology)

New Advances in Antiarrhythmic Drugs

edited by

Norbert Szentandrássy

submission deadline 15 Nov 2024 | 7 articles | Viewed by 9860 | Submission Open

Keywords: antiarrhythmic drugs; ion channel blockers; cardiac action potential; sudden cardiac death; cardiac arrhythmia; proarrhythmic action

(This special issue belongs to the Section Pharmacology)

Applications of Liquid Chromatography Coupled with Mass Spectrometry (LC-MS/MS) in Drug Analysis

edited by Isabela Tarcomnicu and

Valentina Anuta

submission deadline 15 Nov 2024 | 5 articles | Viewed by 7297 | Submission Open

Keywords: pharmaceutical analysis; bioanalysis; liquid chromatography; mass spectrometry; impurities; bioavailability; metabolism; environmental fate

(This special issue belongs to the Section Pharmaceutical Technology)

The Role of Bioactive Compounds in the Prevention of Rheumatoid Arthritis

edited by

Luís Silva

submission deadline 15 Nov 2024 | 2 articles | Viewed by 4338 | Submission Open

Keywords: bioactive compounds; functional foods; nutraceuticals; rheumatoid arthritis; anti-inflamatory activity; anti-inflammatory mediators

(This special issue belongs to the Section Natural Products)

Antidepressant Drug

edited by

Paulina Misztak

submission deadline 15 Nov 2024 | 2 articles | Viewed by 3120 | Submission Open

Keywords: antidepressant; molecular mechanism of drugs; new targets for depression treatment; depression; MDD; animal models of depression; nutrition in depression; small molecules

(This special issue belongs to the Section Pharmacology)

Therapeutic Potential of Vitamin D in Depressive Disorder and Anxiety Disorders

edited by

Ana Lúcia Severo Rodrigues

submission deadline 15 Nov 2024 | 1 articles | Viewed by 1251 | Submission Open

Keywords: antidepressant; anxiety; cholecalcipherol; depression; major depressive disorder; vitamin D

(This special issue belongs to the Section Medicinal Chemistry)

Current Advances in Therapeutic Potential of Sigma Receptor Ligands

edited by Maria Dichiara and

Emanuele Amata

submission deadline 15 Nov 2024 | Viewed by 117 | Submission Open

Keywords: sigma-1 receptor; sigma-2 receptor; TMEM97; cancer; neurodegeneration; neuroprotection; pain; CNS disorders; SAR

(This special issue belongs to the Section Medicinal Chemistry)

Neuropharmacology of Plant Extracts and Their Active Compounds

edited by

Angel Josabad Alonso-Castro

submission deadline 20 Nov 2024 | 6 articles | Viewed by 10322 | Submission Open

Keywords: medicinal plant; mental disorder; preclinical; clinical

(This special issue belongs to the Section Natural Products)

Pharmacological Properties and Therapeutic Potential of Honey Bee Products

edited by

Michał Miłek

and Dana Marcinčáková

submission deadline 20 Nov 2024 | 7 articles | Viewed by 7732 | Submission Open

Keywords: honey; propolis; bee pollen; bee bread; royal jelly; anticancer; anti-inflammatory; antimicrobial; mechanism of action; pharmacological properties

(This special issue belongs to the Section Natural Products)

A Commemorative Special Issue in Honor of Prof. Jolanta Saczko: Pharmaceutical Science in Electrochemotherapy

edited by

Nina Rembiałkowska

submission deadline 20 Nov 2024 | 5 articles | Viewed by 7604 | Submission Open

Keywords: electrochemotherapy; cell membrane permeability; pulsed electric; field anticancer compounds delivery; natural compounds; bioactive compounds; plant extract; cytotoxicity; anticancer activity; antiproliferative activity

(This special issue belongs to the Section Medicinal Chemistry)

Anti-obesity and Anti-aging Natural Products

edited by

Rosario Mare

and

Vincenzo Musolino

submission deadline 20 Nov 2024 | 7 articles | Viewed by 6097 | Submission Open

Keywords: anti-obesity; anti-aging; natural products; herbal remedies; antioxidants; weight management; aging prevention; phytochemicals; botanical extracts; metabolic health; healthy aging

(This special issue belongs to the Section Natural Products)

Pharmacology and Toxicology of Opioids

edited by

Juliana Faria

, Joana Barbosa and

Ricardo Dinis-Oliveira

submission deadline 20 Nov 2024 | 2 articles | Viewed by 3619 | Submission Open

Keywords: opioid toxicity; opioid pharmacodynamics; opioid pharmacokinetics; opioid pharmacogenetics; prescription opioids; toxicity assays; in vivo; in vitro; abuse; dependence

(This special issue belongs to the Section Pharmacology)

Drug Candidates for the Treatment of Obesity, 2nd Edition

edited by

Maria Isabel Cardoso Alonso-Vale

and

Monica Marques Telles

submission deadline 20 Nov 2024 | 3 articles | Viewed by 2970 | Submission Open

Keywords: obesity; appetite supressors; nutraceuticals; plant extracts; lipid metabolism; high-fat diet; adipogenesis

(This special issue belongs to the Section Medicinal Chemistry)

Advances in Pharmacotherapy of Neuropathic Pain

edited by

Marucia Chacur

submission deadline 20 Nov 2024 | 1 articles | Viewed by 1010 | Submission Open

Keywords: analgesic; inflammation; neurotransmitters; neuroplasticity; targeted therapies; neurogenic pain; opioids; cannabinoids

(This special issue belongs to the Section Pharmacology)

New Therapeutic Opportunities for Epigenetic Drugs

edited by Sebastiano Giallongo

submission deadline 20 Nov 2024 | 1 articles | Viewed by 976 | Submission Open

Keywords: epigenetics; aging; personalized medicine; tumor microenvironment; DNA methyltransferase; histone acetyltransferase; histone deacetylases; histone variants; epigenetics-metabolism axis

(This special issue belongs to the Section Biopharmaceuticals)

Advances in Antiparasitic Natural Products

edited by Lizandra Guidi Magalhães

submission deadline 20 Nov 2024 | Viewed by 414 | Submission Open

Keywords: parasites; antiparasitics; natural products

(This special issue belongs to the Section Natural Products)

Peptide Synthesis and Drug Development: Exploring Progress and Potential

edited by

Othman Al Musaimi

, Da’san M.M. Jaradat and Vera D'Aloisio

submission deadline 20 Nov 2024 | Viewed by 340 | Submission Open

Keywords: peptides; enzymatic degradation; drug discovery; formulation; draggability

(This special issue belongs to the Section Biopharmaceuticals)

Recent Advances in Antimicrobial Nano-Drug Delivery Systems

edited by

Luís Alexandre Muehlmann

submission deadline 20 Nov 2024 | Viewed by 227 | Submission Open

Keywords: infectious diseases; antimicrobial resistance; antibiotics; antifungal drugs; nanostructures; pathogen adaptation; nanomedicine

(This special issue belongs to the Section Pharmaceutical Technology)

Inhibitors of κB Kinase (IKK) and Nuclear Factor Kappa-B (NF-κB): Attractive Drug Targets

edited by Guozhou Xu

submission deadline 20 Nov 2024 | Viewed by 220 | Submission Open

Keywords: IkB kinase; kinase activation; protein– protein interaction; ATP-competitive small-molecule kinase inhibitor; inflammatory disease; autoimmune disease

(This special issue belongs to the Section Medicinal Chemistry)

Neurodegenerative Disorders: Computer – Aided Drug Design, Еxperimental Аpproaches and Mechanisms

edited by

Mariyana Atanasova

and

Rumyana Simeonova

submission deadline 20 Nov 2024 | Viewed by 204 | Submission Open

Keywords: neurodegenerative disorders; drug design; molecular docking; Alzheimer’ s disease; pharmacological mechanism

Psychedelics: A New Drug Candidate for Treating Mental Illness

edited by

Raphaël Serreau

and

Sabine Berteina-Raboin

submission deadline 20 Nov 2024 | Viewed by 104 | Submission Open

Keywords: psychedelics drugs; psilocybin; psilocin; pharmacokinetic; pharmacodynamic; new drug candidate; mental diseases

(This special issue belongs to the Section Pharmacology)

Molecular Mechanisms and Therapeutic Resistance in Cancer: Insights from Transcriptional Regulation and Immune Modulation

edited by Hyunmin Kim

submission deadline 20 Nov 2024 | Viewed by 79 | Submission Open

Keywords: cancer; therapeutic resistance; transcriptional dysregulation; bioinformatics; artificial intelligence; machine learning; cancer therapy; resistance mechanisms; cancer treatment; gene regulation; multi-omics multi-modal single cell; cancer cell heterogeneity

(This special issue belongs to the Section Pharmacology)

Plant-Derived Nanotherapeutics and Nanocarriers: Recent Progress and Future Directions

edited by

Estefânia V.R. Campos

and

Jhones Luiz De Oliveira

submission deadline 22 Nov 2024 | 7 articles | Viewed by 16902 | Submission Open

Keywords: plant-based nanomaterials; green nanomaterials; drug delivery; natural nanotherapeutics; pharmaceutical nanoformulations; biogenic synthesis; phytonanotechnology

(This special issue belongs to the Section Pharmaceutical Technology)

Interaction between Nanoparticles and Antibiotics：Against Antimicrobial Resistance

edited by

Isabella Macário Ferro Cavalcanti

and Maria Carolina Accioly Brelaz de Castro

submission deadline 22 Nov 2024 | 3 articles | Viewed by 5414 | Submission Open

Keywords: microorganisms; resistance; pharmaceutical research; nanotechnology

Orodispersible Tablets: New Advances in Preparation Technologies

edited by

Witold Brniak

and

Aleksander Mendyk

submission deadline 22 Nov 2024 | 1 articles | Viewed by 927 | Submission Open

Keywords: orodispersible tablets; orally disintegrating tablets; superdisintegrants; co-processed excipients; direct compression; 3D printing

(This special issue belongs to the Section Pharmaceutical Technology)

Design, Synthesis, Evaluation and Biopharmaceutical Uses of Imatinib, Nilotinib and Their Analogues

edited by

Alexandros D. Tselepis

, Dimitrios Alivertis and Pinelopi Voulgari

submission deadline 22 Nov 2024 | Viewed by 378 | Submission Open

Keywords: cancer; inhibitors; Imatinib; Nilotinib; protein kinases; target therapy

(This special issue belongs to the Section Medicinal Chemistry)

Pharmacotherapy of Inflammatory Bowel Disease

edited by

Wolfgang Kruis

submission deadline 23 Nov 2024 | Viewed by 282 | Submission Open

Keywords: Treatment of Crohn's Disease; treatment of ulcerative Colitis; mesalazine for ulcerative colitis; mesalazine for Crohn's Disease; antibody strategies in IBD; small molecules for IBD; conservative managenment of Crohn's fistula; therapy for extraintestinal manifestations; new endpoints for treatment

(This special issue belongs to the Section Pharmacology)

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