Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Pediatric Drug Formulations submission deadline 25 Sep 2025 | 3 articles | Viewed by 5633 | Submission Open
Keywords: pediatric dosage forms; child-friendly dosage forms; age-appropriate dosage forms; acceptability; administration devices; taste-masking; compounded pediatric formulations
(This special issue belongs to the Section Pharmaceutical Technology)
Drug Safety and Risk Management in Clinical Practice
edited by Andreea Maria Farcas
submission deadline 25 Sep 2025 | 3 articles | Viewed by 4187 | Submission Open
Keywords: drug safety; adverse drug reactions; risk minimization measures; effectiveness of risk minimization measures; drug utilization studies
(This special issue belongs to the Section Pharmacology)
Current Advances in Therapeutic Potential of Sigma Receptor Ligands
edited by Maria Dichiara and
submission deadline 25 Sep 2025 | 3 articles | Viewed by 3686 | Submission Open
Keywords: sigma-1 receptor; sigma-2 receptor; TMEM97; cancer; neurodegeneration; neuroprotection; pain; CNS disorders; SAR
(This special issue belongs to the Section Medicinal Chemistry)
Heterocyclic Compounds in Medicinal Chemistry, 2nd Edition submission deadline 25 Sep 2025 | 2 articles | Viewed by 3670 | Submission Open
Keywords: heterocycles; drug design; drug discovery; bioactive compounds; structure-based drug design; structure– activity relationship; in silico studies; ADMET properties; multicomponent reactions; phytochemicals
(This special issue belongs to the Section Medicinal Chemistry)
Drug Treatment of Cancers
edited by
submission deadline 25 Sep 2025 | 1 articles | Viewed by 3466 | Submission Open
Keywords: cancer; oncology; chemotherapy; immunotherapy; targeted therapy; precision medicine; liquid biopsy; circulating tumor DNA (ctDNA); imaging
(This special issue belongs to the Section Pharmacology)
Pharmacotherapy of Dyslipidemias, 2nd Edition submission deadline 25 Sep 2025 | 1 articles | Viewed by 2647 | Submission Open
Keywords: atherosclerosis; dyslipidemia; endothelial dysfunction; fatty acids; high-fat diet; hyperlipidemia; hypertriglyceridemia; polyunsaturated fatty acids; PUFA; statins
(This special issue belongs to the Section Medicinal Chemistry)
Psychedelics: A New Drug Candidate for Treating Mental Illness submission deadline 25 Sep 2025 | 2 articles | Viewed by 1703 | Submission Open
Keywords: psychedelics drugs; psilocybin; psilocin; pharmacokinetic; pharmacodynamic; new drug candidate; mental diseases
(This special issue belongs to the Section Pharmacology)
Challenges in the Development of PET and SPECT Radiotracers: Innovative Ideas with Negative Outcomes
edited by Magali Toussaint and Barbara Wenzel
submission deadline 25 Sep 2025 | 2 articles | Viewed by 1661 | Submission Open
Keywords: radiotracer development; positron emission tomography (PET); single-photon emission computed tomography (SPECT); negative results; diagnostic radiotracers; therapeutic radiopharmaceuticals; radiolabeling; automated synthesis and GMP; pre-clinical studies; medicinal chemistry
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Peptide Biomaterials for Pharmaceutical Applications
edited by , Sergio Alberto Bernal Chavez and
submission deadline 25 Sep 2025 | 1 articles | Viewed by 1650 | Submission Open
Keywords: peptides; pharmaceutical applications; nanomedicine; peptide materials; peptide conjugates; drug delivery systems; nanocarriers; biologics
(This special issue belongs to the Section Pharmaceutical Technology)
Medicinal Potential of Cannabidiol and New Structural Analogs
edited by
submission deadline 25 Sep 2025 | 1 articles | Viewed by 1624 | Submission Open
Keywords: cancer; inflammation; pain; analgesia; cannabidiol; parkinson disease; huntington disease; alzheimer disease
(This special issue belongs to the Section Medicinal Chemistry)
Immunogenomics for Drug Discovery in Leukemia
edited by and Adolfo Martínez-Tovar
submission deadline 25 Sep 2025 | Viewed by 1557 | Submission Open
Keywords: leukemia; hematological diseases; immunogenomics; omics studies; experimental models; therapeutic approaches
(This special issue belongs to the Section Medicinal Chemistry)
Therapeutic Applications of Micro-RNA in Cancer Management submission deadline 25 Sep 2025 | 1 articles | Viewed by 1178 | Submission Open
Keywords: cancer; miRNAs; therapeutic applications; miRNA treatments
(This special issue belongs to the Section Biopharmaceuticals)
Advances in Hybrid Anticancer Drugs: Innovations and Therapeutic Potential
edited by
submission deadline 25 Sep 2025 | 1 articles | Viewed by 993 | Submission Open
Keywords: drug design; molecular hybrids; anticancer agents; privileged scaffold; multiple mechanisms of action
(This special issue belongs to the Section Medicinal Chemistry)
Novel Drug Compositions for Ischemic Stroke: Mechanisms and Clinical Applications submission deadline 25 Sep 2025 | 1 articles | Viewed by 984 | Submission Open
Keywords: ischemic stroke; novel delivery systems; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; tissue engineering
(This special issue belongs to the Section Pharmacology)
Next-Generation Antibiotic Strategies Against Drug-Resistant Bacteria
edited by , Nicholas Smith and Parikshit Padhi
submission deadline 25 Sep 2025 | 1 articles | Viewed by 727 | Submission Open
Keywords: persisters and AMR; combination pharmacotherapy; drug repurposing; antibiotic adjuvants; next-generation beta lactamase inhibitors; small molecule inhibitors; bacteriophage therapy; peptides and CRISPR-based antimicrobials; novel therapeutics; heteroresistance
(This special issue belongs to the Section Pharmacology)
Advances in the Treatment of Leukemia and Lymphomas
edited by , Karina Braga Gomes and Maria Das Graças Carvalho
submission deadline 25 Sep 2025 | 1 articles | Viewed by 701 | Submission Open
Keywords: leukemias; lymphomas; chemotherapy; target therapy; immunotherapy; kinase inhibitors; hematologic oncology; therapy; treatment
(This special issue belongs to the Section Medicinal Chemistry)
Expanding the Cancer Drug Discovery Toolbox: A Focus on Protein Degradation, Allosteric Modulation, and Covalent Inhibition
edited by Rita Maria Concetta Di Martino and
submission deadline 25 Sep 2025 | 1 articles | Viewed by 641 | Submission Open
Keywords: protein degradation; proteolysis targeting chimeras; hydrophobic tags; molecular glues; allosteric modulators; covalent inhibitors
(This special issue belongs to the Section Medicinal Chemistry)
Combating Drug Resistance in Cancer submission deadline 25 Sep 2025 | 1 articles | Viewed by 434 | Submission Open
Keywords: multidrug resistance; cancer cells; cancer drug resistance; overcoming chemoresistance; targeted cancer therapies; novel anti-cancer strategies; tumor resistance mechanisms; innovative cancer treatments; reversing drug resistance
(This special issue belongs to the Section Medicinal Chemistry)
Computer-Aided Drug Design and Drug Discovery, 2nd Edition submission deadline 25 Sep 2025 | Viewed by 242 | Submission Open
Keywords: chemoinformatics; bioinformatics; molecular modeling; virtual screening; molecular docking; quantitative structure– activity relationship (QSAR); pharmacophore modeling; target identification; repurposing; ADME-T prediction
(This special issue belongs to the Section Medicinal Chemistry)
Application of Supercritical Fluids in Pharmaceutical Science submission deadline 25 Sep 2025 | Viewed by 220 | Submission Open
Keywords: supercritical fluids; scCO2; drug formulation; bioavailability; green chemistry; drug delivery systems; nanoparticle encapsulation; bioactive compound extraction; pharmaceutical purification; controlled release; sustainable pharmaceutical processes
(This special issue belongs to the Section Pharmaceutical Technology)
Recent Research in Therapeutic Potentials of Venoms
edited by Samuel Teixeira, Daiana Silva Lopes and
submission deadline 25 Sep 2025 | Viewed by 163 | Submission Open
Keywords: bioprospecting; biotechnological tools; snake venom toxins; drug discovery; natural products; pharmacological applications; molecular targets of venom toxins; toxicology; peptide therapeutics; venom-based drug delivery
(This special issue belongs to the Section Natural Products)
Advances in Drug Analysis and Drug Development, 2nd Edition
edited by and Ana Mornar
submission deadline 25 Sep 2025 | Viewed by 111 | Submission Open
Keywords: analytical methodology; chromatographic techniques; spectrometric techniques; thermal analysis techniques; sample preparation; drug stability; compatibility study; bioavailability studies; therapeutic drug monitoring; quality by design in pharmaceutical analysis
(This special issue belongs to the Section Pharmaceutical Technology)
Design, Synthesis and Evaluation of Novel 18F Radiotracers
edited by and John E. Shively
submission deadline 25 Sep 2025 | Viewed by 95 | Submission Open
Keywords: positron emission tomography (PET); fluorine-18 (F-18); radiotracer development; molecular imaging; non-invasive diagnostic technique; synthetic methodologies; preclinical evaluation
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Innovative Drug Strategies in Chronic Disease Management: Addressing Non-Adherence and Improving Therapeutic Outcomes submission deadline 26 Sep 2025 | 1 articles | Viewed by 819 | Submission Open
Keywords: adherence; persistence; chronic diseases; therapeutic strategies; individualized therapy; personalized medicine; clinical pharmacology; clinical trials; observational studies; real-world data studies
(This special issue belongs to the Section Pharmacology)
Innovative Drug Delivery Systems for Enhanced Dissolution and Bioavailability
edited by Marival Bermejo, and Covadonga Álvarez-Álvarez
submission deadline 26 Sep 2025 | Viewed by 173 | Submission Open
Keywords: drug dissolution enhancement; oral bioavailability improvement; poorly soluble drugs; solid dispersions; nanoparticle drug delivery; amorphous formulations; 3D printing in pharmaceuticals; advanced drug-polymer systems; advanced excipients for solubility enhancement; controlled drug release
(This special issue belongs to the Section Pharmaceutical Technology)
Computational Predictions of Molecules with Potential Therapeutic Effects
edited by
submission deadline 30 Sep 2025 | 6 articles | Viewed by 9359 | Submission Open
Keywords: biophysics; medicinal chemistry; drug discovery; molecular docking; molecular dynamics; structure-activity relationships; computer-aided drug design (CADD)
(This special issue belongs to the Section Medicinal Chemistry)
Recent Advances in Drug Metabolism, Transport, and Pharmacokinetics
edited by Agnieszka Bienert and
submission deadline 30 Sep 2025 | 2 articles | Viewed by 5109 | Submission Open
Keywords: pharmacokinetic analysis; analytical methods suitable for pharmacokinetics studies; pharmacogenetics in drug pharmacokinetics; clinical pharmacokinetics; drug concentrations in plasma and tissue; population PK modeling; drug metabolic pathways; drug transport across barriers
(This special issue belongs to the Section Pharmacology)
Advances in Ophthalmic Drug Discovery and Delivery: From Targets to Treatments
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 1943 | Submission Open
Keywords: retinal degeneration; glaucoma; cataract; diabetic retinopathy; drug target; drug delivery; drug candidate; gene therapy; stem cells; natural products; Artificial Intelligence
(This special issue belongs to the Section Pharmacology)
Advances in Pharmacotherapy for Nasal Disorders in Rhinology
edited by
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1595 | Submission Open
Keywords: rhinology; CRS; asthma; nasal polyps; biologics; airflow; children; QoL; artificial intelligence; olfaction; chemical senses
(This special issue belongs to the Section Pharmacology)
Innovative Analytical Techniques and Nanotechnology in Natural Products Analysis and Drug Development
edited by Jinchao Wei and
submission deadline 30 Sep 2025 | Viewed by 370 | Submission Open
Keywords: natural product; Chinese medicine; drug development; analytical technique; nanotechnology; spectrometry; chromatography; sensors; formulation
(This special issue belongs to the Section Natural Products)
Effects of Drug Abuse and Its Consequences on Health submission deadline 30 Sep 2025 | Viewed by 223 | Submission Open
Keywords: psychoactive substances; drug abuse; toxicological effects; neurotoxicity; substance use disorder; biomarkers of toxicity; public health impact; addiction mechanisms; harm reduction strategies; novel psychoactive substance (NPS)
(This special issue belongs to the Section Medicinal Chemistry)
Advancements and Possibilities for the Treatment of Idiopathic Inflammatory Myopathies
edited by and Samuel Katsuyuki Shinjo
submission deadline 30 Sep 2025 | Viewed by 158 | Submission Open
Keywords: anti-synthetase syndrome; dermatomyositis; polymyositis; inflammatory myopathy; myositis; treatment
(This special issue belongs to the Section Pharmacology)
Advances in Small-Molecule Therapeutics Targeting Signaling Pathways
edited by
submission deadline 30 Sep 2025 | Viewed by 137 | Submission Open
Keywords: small molecules; natural compounds; synthetic compounds; signaling pathways; drug design; drug development; HTS; computational tools; biological evaluations; QSAR; bioavailability; pharmacokinetics
(This special issue belongs to the Section Medicinal Chemistry)
Advancements in Cardiometabolic Pharmacology Research submission deadline 30 Sep 2025 | Viewed by 64 | Submission Open
Keywords: cardiometabolic diseases; pharmacological interventions; drug discovery and development; preclinical models in cardiometabolic research; molecular mechanisms of cardioprotection; bioactive natural compounds; gut microbiome and metabolism; inflammation and oxidative stress in cardiometabolic disease; translational pharmacology
(This special issue belongs to the Section Pharmacology)
Pharmacotherapy for Alzheimer’s Disease submission deadline 5 Oct 2025 | 5 articles | Viewed by 5672 | Submission Open
Keywords: Alzheimer’ s disease; pharmacotherapy; therapeutic editing tools; repurposing existing therapeutics; multi-target-directed ligands; preclinical studies; neurodegeneration; drug development; neuroprotection; cannabinoid-based pharmaceuticals; single-molecule drugs or whole-plant extracts of Cannabis sativa L.
(This special issue belongs to the Section Pharmacology)
Melatonin Applications in Pharmaceutical Science submission deadline 5 Oct 2025 | Viewed by 121 | Submission Open
Keywords: melatonin; pineal gland; epigenetics; pharmacology; physiology; immunology; pharmaceutics; novel therapies; cancer
(This special issue belongs to the Section Pharmacology)
The Discovery and Development of Drug Ingredients from Food Sources
edited by and Dorota Olender
submission deadline 10 Oct 2025 | 2 articles | Viewed by 1280 | Submission Open
Keywords: natural compounds; food; antioxidants; biological activity of natural substances; the influence of food on health
(This special issue belongs to the Section Natural Products)
Affective Disorders Psychopharmacology
edited by Danilo Arnone
submission deadline 15 Oct 2025 | 2 articles | Viewed by 7452 | Submission Open
Keywords: psychopharmacology; affective disorders; mood disorders; major depressive disorders; bipolar affective disorders
(This special issue belongs to the Section Pharmacology)
Pharmacological Activity and Application of Polyphenolic Compounds
edited by
submission deadline 15 Oct 2025 | Viewed by 866 | Submission Open
Keywords: phenolic compounds; biological potential; pharmacological activity; phenolic applications; health promoters; chronic diseases
(This special issue belongs to the Section Natural Products)
Recent Advances in Overcoming Therapy Resistance in Cancer
edited by
submission deadline 15 Oct 2025 | Viewed by 116 | Submission Open
Keywords: cancer therapy resistance; hematological malignancies; solid tumors; targeted therapies; tumor microenvironment; drug resistance mechanisms; epigenetic factors; translational oncology; novel therapeutic strategies; biomarkers of resistance
The Modes of Action of Herbal Medicines and Natural Products, 2nd Edition
edited by Hongnan Cao
submission deadline 15 Oct 2025 | Viewed by 110 | Submission Open
Keywords: herbal compounds; natural products; pharmacokinetics and pharmacodynamics of natural products; herbal medicines; herbal therapies
(This special issue belongs to the Section Natural Products)
Applications of Beehive Products for Wound Repair and Skin Care
edited by Simona Martinotti
submission deadline 20 Oct 2025 | 3 articles | Viewed by 7450 | Submission Open
Keywords: anti-aging; antibacterial properties; healing properties; honey; propolis; bee venom; wound repair; skin care
(This special issue belongs to the Section Natural Products)
Sirtuins as Novel Biological Targets for Pharmacological Intervention in Physiology and Pathology—2nd Edition submission deadline 20 Oct 2025 | 1 articles | Viewed by 376 | Submission Open
Keywords: sirtuins; metabolism; cancer; hypoxia; damage recovery; cell death
(This special issue belongs to the Section Pharmacology)
Adjuvant Therapies for Cancer Treatment: 2nd Edition
edited by
submission deadline 22 Oct 2025 | 4 articles | Viewed by 2857 | Submission Open
Keywords: drug repurposing; combined therapies; new compounds; drug resistance; chemosensitization; antitumoral strategies
(This special issue belongs to the Section Pharmacology)
Structural Insights into Protein Kinases-Targeted Therapies: Overcoming Resistance and Advancing Precision Oncology
edited by David Hecht
submission deadline 22 Oct 2025 | Viewed by 210 | Submission Open
Keywords: protein kinases inhibitor resistance; structural biology of of protein kinases; computational modeling; drug design; preclinical and clinical studies; precision oncology; ALK resistance for personalized medicine
(This special issue belongs to the Section Medicinal Chemistry)
Pharmaceutical Modeling and Real-World Data: Advancing Prescribing and Monitoring submission deadline 22 Oct 2025 | Viewed by 148 | Submission Open
Keywords: adverse drug reaction; generalizability and transportability; machine learning; pharmacodynamics; pharmaceutical monitoring; pharmacokinetics; quantitative systems in pharmacology; real-world data; real-world evidence; therapeutic drug monitoring
(This special issue belongs to the Section Pharmacology)
Use of Encapsulating Polymers of Active Compounds in the Pharmaceutical Industry
edited by Alba Adriana Vallejo-Cardona, Inocencio Higuera-Ciapara and
submission deadline 24 Oct 2025 | 1 articles | Viewed by 1407 | Submission Open
Keywords: polymer; drug delivery; active compounds; encapsulation; pharmaceutical industry; natural polymers; synthetic polymers
(This special issue belongs to the Section Pharmaceutical Technology)
New and Emerging Treatment Strategies for Gastrointestinal Diseases submission deadline 25 Oct 2025 | 7 articles | Viewed by 23696 | Submission Open
Keywords: gastrointestinal diseases; gastrointestinal homeostasis; gastrointestinal injuries; gastrointestinal disturbances; dysbiosis; bile acid; inflammatory bowel diseases; diarrhea
(This special issue belongs to the Section Pharmacology)
Pharmacological Therapies for Stress-Related Disorders and Autism Spectrum Disorder
edited by and
submission deadline 25 Oct 2025 | 4 articles | Viewed by 18275 | Submission Open
Keywords: new targets and therapies for stress-related disorders; molecular mechanism of drugs; ASD; PTSD; MDD; antidepressant; depression; animal model for depression; ASD; microbiome; gut-brain axis; brain electrophysiology; neuron activity in ASD
(This special issue belongs to the Section Pharmacology)
Pharmacotherapy of Thromboembolism submission deadline 25 Oct 2025 | 5 articles | Viewed by 13619 | Submission Open
Keywords: activated factor XI inhibitors; platelet glycoprotein VI antagonists; PAR4 antagonists; PI3K inhibitorslong-term anticoagulation; antiplatelet therapy; novel antithrombotic drugs; anticoagulation-related bleeding; post-vascular procedure-related thrombosis
(This special issue belongs to the Section Pharmacology)
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