Relevant Nutritional, Biochemical and Molecular Disorders in CKD

Dear Colleagues,

Chronic kidney disease (CKD) has become one of the main public health problems because of demographic aging. Worldwide, an estimated 500 million adults suffer from CKD. Early stages of CKD are associated with a significant increase in cardiovascular morbidity. 

The requirement and metabolism of nutrients, vitamins, and essential and non-essential elements varies during the different stages of CKD; in some of them the deficit is the rule, while in others excess is the main problem leading to clinical, biochemical and molecular abnormalities. Understanding the applicable nutritional principles and avoiding overweight, malnutrition, as well as bone and cardiovascular disorder remain critical issues in CKD.

Several aspects of great relevance in CKD will be included in this Special Issue of Nutrients, starting with the importance of the nutritional support in children with CKD and the overall benefits of working with a dietitian. Critical aspects in current CKD management, such as the dietary patterns in relationship with potassium, magnesium, vitamin D, and antioxidants, will be discussed.

Metabolic and vascular disorders, inflammation, regulation by miRNAs, the microbiota, intestinal hormones, short chain fatty acids, molecules derived from adipose tissue, bariatric surgery, the association with the bone and vascular axis, malnutrition, inflammation and atherosclerosis (MIA) syndrome, the impact of malnutrition on cognitive impairment, the relationship between serum albumin levels and mortality, and the role of diabetes and kidney transplantation in bone and vessel health will be discussed. The topics will be addressed keeping a translational perspective.

Prof. Dr. Jorge B. Cannata-Andía
Dr. Sara Panizo
Dr. Cristina Alonso-Montes
Dr. Natalia Carrillo-López
Guest Editors

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