Diet, Gut Microbiota, and Gastrointestinal Disease

Dear Colleagues,

Gastrointestinal diseases are a significant cause of morbidity and mortality worldwide. The recent advent of metagenomic techniques has highlighted the important role of the gut microbiota in human pathology.

The gut provides a vast interface area for the interaction between the host and the intestinal microbiota. At this level, the intricate crosstalk involves bacteria, surface cells, immune cells, endothelial cells, and nervous terminals. Moreover, there are several possible mediators involved in these interactions, such as microbial products, cytokines, and signalling factors, which make the scenario even more complex.

In this intricate conundrum, recent evidence has highlighted that some mechanisms of carcinogenesis may be strictly linked to dysbiosis and the detrimental effects of a derangement in the gut microbiota metabolism. Diet is a crucial modulator of the gut microbiota, and thus, it can be both detrimental, increasing the risk of gastrointestinal diseases via a more inflammatory and unhealthy gut microbiota, as well as helpful in restoring a balance in the gut microenvironment, resulting in a protective effect on disease development.

The Special Issue “Diet, Gut Microbiota, and Gastrointestinal Disease” aims to provide a platform for researchers with a keen interest in the study of this dynamic topic, specifically the interplay between diet/nutritional supplements, gut microbiota, and gastrointestinal diseases including cancer. Original articles and reviews focusing on this topic are welcome.

Dr. Francesca Romana Ponziani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.