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Novel Therapeutic Approaches and Nutritional Strategies for Celiac Disease and Gluten-Related Disorders

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 25 October 2026 | Viewed by 203

Editors


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Guest Editor
Department of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy
Interests: celiac disease; non-celiac gluten/wheat sensitivity; gluten-related disorders; amylase trypsin inhibitors; food allergy; food sensitivity; food intolerance; irritable bowel syndrome; functional gastrointestinal disorders; leaky gut; microbiome; small bowel enteropathies
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Arcispedale Sant'Anna, Azienda Ospedaliero-Universitaria di Ferrara Via Aldo Moro, 8 Cona, 44124 Ferrara, Italy
2. Policlinico Paolo Giaccone, Via del Vespro 129, 90127 Palermo, Italy
Interests: nutrition; celiac disease; gluten- related disorders; probiotics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to this Special Issue of Nutrients, entitled ‘Novel Therapeutic Approaches and Nutritional Strategies for Celiac Disease and Gluten-Related Disorders.’

Celiac disease (CeD) and gluten-related disorders (GRD) are a growing global health concern, with increasing prevalence and significant clinical, nutritional, and psychosocial implications. Although the gluten-free diet (GFD) is the only available treatment, it is often insufficient to fully control symptoms or to ensure optimal nutritional status and quality of life (QoL). Moreover, strict dietary adherence is challenging, and inadvertent gluten exposure is common. In recent years, advances in immunology, gastroenterology, food science, and nutrition have led to the development of innovative therapeutic approaches and novel nutritional strategies to complement or, in selected cases, overcome the limitations of the GFD. This rapidly evolving field highlights the need for an integrated, multidisciplinary perspective to improve patient outcomes and to better understand the pathophysiology and management of these disorders.

This Special Issue aims to provide a comprehensive and up-to-date overview of emerging therapeutic options and nutritional strategies for CeD and GRD, focusing on innovative dietary interventions, novel pharmacological and non-pharmacological therapies, and their nutritional implications. The goal is to promote scientific discussion, stimulate future research, and support evidence-based nutritional and therapeutic approaches that may improve CeD management and patient QoL.

In this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following:

  • Novel pharmacological and non-pharmacological therapies for CeD and GRD.
  • Innovative nutritional strategies and dietary interventions beyond the traditional GFD.
  • Gluten detoxification, enzymatic therapies, and food processing technologies in GRD.
  • Nutritional deficiencies, metabolic alterations, and personalized nutrition in CeD and GRD.
  • Role of the gut microbiota and probiotics/prebiotics in CeD and GRD.
  • QoL, adherence to dietary treatments, monitoring of therapeutic and nutritional interventions, and patient-centered outcomes in CeD and GRD.

Interdisciplinary or multi-center studies are particularly encouraged for submission.

We look forward to receiving your contributions.

Dr. Giacomo Caio
Dr. Lisa Lungaro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • celiac disease
  • gluten free diet (GFD)
  • gluten-related disorders (GRD)
  • novel pharmacological and non-pharmacological therapies
  • nutrition
  • gut microbiota
  • probiotics
  • prebiotics

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Published Papers

This special issue is now open for submission.
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