Omega-3 Polyunsaturated Fatty Acids in Health and Disease
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 15 January 2025 | Viewed by 48
Special Issue Editors
2. Immunology Program and Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore 119077, Singapore
Interests: pro-resolving lipid mediators; resolution of inflammation; innate immunity; efferocytosis; granulocyte trafficking; respiratory diseases; immunopharmacology; natural products; targeted lipidomics
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; natural product synthesis; organic chemistry; lipid mediators; resolution of inflammation; lipidomics; analytical chemistry; mass spectrometry; spectroscopy
Interests: inflammation; polyunsaturated fatty acids; immune response; immunology; tissue engineering; cell culture dermatology; T cell biology; immunohistochemistry; histological staining
Special Issue Information
Dear Colleagues,
Since Bang and Dyerberg’s omega-3 discovery just over fifty years ago, an impressive body of literature on the chemistry and biology of essential fatty acid-derived products and related structures has been reported. Advances in this field have uncovered a complex family of molecules with important physiological roles. In an infant’s brain, approximately 50–60% of the brain weight comprises lipids, of which 35–40% are omega-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). While fish biosynthesize omega-3 PUFAs de novo, humans must obtain these essential nutrients from diet. The therapeutic and health-promoting effects of omega-3 fatty acids have been extensively studied in chronic inflammatory and autoimmune diseases through various mechanisms, including modifications in cell membrane lipid composition, gene expression, cellular metabolism, and signal transduction. DHA and EPA-derived mediators, including resolvins, protectins, and maresins, are potent autacoids that dampen inflammation. In recent years, a growing interest in omega-3 PUFAs in human health has occurred at a rapid pace, with new results expanding our understanding of their roles in immunomodulation and in the endogenous resolution of inflammation.
In this Special Issue of Nutrients, our goal is to highlight up-to-date research on essential omega-3 fatty acids and related products, focusing on their effects on human health across the lifespan and the opportunities they offer for the development of novel therapeutic agents. We welcome various types of manuscript submissions, including original research and review articles.
Dr. Hong Yong Peh
Dr. Robert Nshimiyimana
Dr. Mélissa Simard
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- docosahexaenoic acid (DHA)
- eicosapentaenoic acid (EPA)
- resolution of inflammation
- neuroprotection
- cardioprotection
- mental health
- alternate sources of omega-3s
- aging
