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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Sustainable Electrochemical Platforms for Clinical and Environmental Determination submission deadline 30 Dec 2026 | Viewed by 158 | Submission Open
Keywords: sustainable electrochemistry; electrochemical biosensors; environmental monitoring; green synthesis; point-of-care diagnostics; biomass-derived carbon; emerging pollutants; nanocomposites; screen-printed electrodes; molecular detection
(This special issue belongs to the Section Electrochemistry)
Novel Polymer Materials for Environmental Applications submission deadline 30 Dec 2026 | Viewed by 158 | Submission Open
Keywords: bioplastics; polymer biocomposites; ecological packaging; polymer waste recovery; microplastics; photocatalytic polymers; conductive polymers; polymeric membranes; biodegradation of polymers
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Advances in Organic Chemistry
edited by , Antonia Di Mola and
submission deadline 31 Dec 2026 | 23 articles | Viewed by 37992 | Submission Open
Keywords: organic synthesis; organic chemistry research; theoretical study; reaction mechanisms; catalysis
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Chemical Biology submission deadline 31 Dec 2026 | 13 articles | Viewed by 30635 | Submission Open
Keywords: bioorthogonal chemistry; peptides; nucleic acids; proteins; analytical methods; chemical inhibitors; chemical probe; ubiquitination; structure-activity relationship
(This special issue belongs to the Section Chemical Biology)
30th Anniversary of Molecules: Recent Advances and the Next in Macromolecular Chemistry submission deadline 31 Dec 2026 | 10 articles | Viewed by 29586 | Submission Open
Keywords: macromolecular chemistry; synthetic polymers; natural polymers; polymerization mechanisms and kinetics; supramolecular self-assembly; biological macromolecules
(This special issue belongs to the Section Macromolecular Chemistry)
30th Anniversary of Molecules—Recent Advances in Food Chemistry
edited by and Marta Coelho
submission deadline 31 Dec 2026 | 22 articles | Viewed by 29246 | Submission Open
Keywords: functional foods; nutraceuticals; bioactive compounds; analytical techniques; by-products; food chemistry
(This special issue belongs to the Section Food Chemistry)
Featured Review Papers in Food Chemistry—2nd Edition
edited by
submission deadline 31 Dec 2026 | 8 articles | Viewed by 25699 | Submission Open
Keywords: food analysis; food additives; food supplements; functional foods; physicochemical properties; agro-food wastes recycling; bioaccessibility and bioavailability; food stability; food security
(This special issue belongs to the Section Food Chemistry)
Advances in Coordination Chemistry, 3rd Edition
edited by Juan Niclós-Gutiérrez and
submission deadline 31 Dec 2026 | 8 articles | Viewed by 21681 | Submission Open
Keywords: synthesis strategies for novel coordination compounds; coordination compounds with tailor-made ligands for specific applications; coordination compounds with multitopic ligands; single-crystal XRD structures and dimensionality of metal complexes; metal–organic frameworks and their applications; molecular recognition in mixed ligand–metal complexes at the molecular and/or supra-molecular levels; model metal complexes from the bioinorganic frontier of biological chemistry; DFT and other theoretical approaches for inter-ligand interactions in metal complexes
(This special issue belongs to the Section Inorganic Chemistry)
Biologically Active Molecules: Extraction Strategies, Therapeutic Potential and Biomedical Perspective
edited by
submission deadline 31 Dec 2026 | 10 articles | Viewed by 21007 | Submission Open
Keywords: natural bioactive components; extraction techniques; therapeutic and biomedical profiling
(This special issue belongs to the Section Medicinal Chemistry)
30th Anniversary of Molecules—Recent Advances in Applied Chemistry submission deadline 31 Dec 2026 | 13 articles | Viewed by 20539 | Submission Open
Keywords: applied chemistry; new molecules and natural materials; analytical methods and techniques; electrochemistry and energy; biodegradable materials and medicines; environment and green chemistry; theoretical chemistry
(This special issue belongs to the Section Applied Chemistry)
Review Papers in Analytical Chemistry, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 19655 | Submission Open
Keywords: analytical chemistry; analytical spectroscopy; environmental sciences; medical science; forensic science; cultural heritage; food analysis
(This special issue belongs to the Section Analytical Chemistry)
30th Anniversary of Molecules—Recent Advances in Inorganic Chemistry submission deadline 31 Dec 2026 | 10 articles | Viewed by 17117 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; solid-state chemistry; nanomaterials; organometallics; transition and main group metal chemistry; catalysis; bioinorganic chemistry
(This special issue belongs to the Section Inorganic Chemistry)
The 30th Anniversary of Molecules—Recent Advances in Natural Products Chemistry submission deadline 31 Dec 2026 | 8 articles | Viewed by 15476 | Submission Open
Keywords: natural compounds; bioactive molecules; drug discovery; pharmacological activity; formulations, drug delivery systems; food applications and additives; cosmetic applications; synthesis
(This special issue belongs to the Section Natural Products Chemistry)
30th Anniversary of Molecules—Recent Advances in Analytical Chemistry submission deadline 31 Dec 2026 | 7 articles | Viewed by 12842 | Submission Open
Keywords: chromatography and advanced mass spectrometry; atomic spectroscopy and elemental mass spectrometry; molecular spectroscopy; miniaturization of analytical instruments; ohmics; nanomaterials and sensors; automation and high-throughput screening; single-cell analysis; non-invasive analysis/techniques; green analytical chemistry
(This special issue belongs to the Section Analytical Chemistry)
Applied Chemistry in Europe, 2nd Edition
edited by and Gianluca D'Abrosca
submission deadline 31 Dec 2026 | 9 articles | Viewed by 12308 | Submission Open
Keywords: nano-materials; environmental chemistry; chemical synthesis; green chemistry; theoretical chemistry analytical methods
(This special issue belongs to the Section Applied Chemistry)
30th Anniversary of Molecules—Recent Advances in Bioorganic Chemistry submission deadline 31 Dec 2026 | 9 articles | Viewed by 12245 | Submission Open
Keywords: bioorganic chemistry; chemoenzymatic synthesis; biocatalysis; biomimetic synthesis; biomolecular interactions; functional biomolecules; molecular recognition
(This special issue belongs to the Section Bioorganic Chemistry)
Advances and Opportunities of Natural Products in Drug Discovery submission deadline 31 Dec 2026 | 10 articles | Viewed by 12082 | Submission Open
Keywords: natural products; drug discovery; pharmacological activity; biological activity; new compounds
(This special issue belongs to the Section Natural Products Chemistry)
30th Anniversary of Molecules—Recent Advances in Green Chemistry
edited by
submission deadline 31 Dec 2026 | 10 articles | Viewed by 10957 | Submission Open
Keywords: green catalysts; green extraction and processing; chemistry based on natural products; bio-based solvents with sub- and super-critical fluids; microwave and ultrasound; organic reaction in green solvents; bioconversion of biomass and sustainable biomaterials; creating fine chemicals and polymers from renewable resources; green nanotechnology; green analytical chemistry; green degradation process
(This special issue belongs to the Section Green Chemistry)
Modern Trends and Solutions in Analytical Chemistry in Poland
edited by
submission deadline 31 Dec 2026 | 9 articles | Viewed by 10834 | Submission Open
Keywords: analytical and physical chemistry; separation sciences; chromatographic methods and related techniques (HPLC, SPE, SFC, GC, CZE, UPLC, GC × GC, and others); sample preparation and extraction techniques (SPE, QuEChERS/d-SPE, SPME, SBSE, HFLPME, DLLME, FUSLE, and others); detection techniques (DAD, FLD, MS, MS/MS, and others); spectrometry; bioanalytics; proteomics, metabolomics, and lipidomics; nanotechnology; environmental sciences; natural product chemistry (isolation, identification and quantification of bioactive compounds, and in vitro and then in vivo investigations on their biological activity); food analysis and food safety; xenobiotics analysis in environmental, biological, and food samples; chemometrics and statistical analysis
(This special issue belongs to the Section Analytical Chemistry)
Advance in Radiochemistry, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 6 articles | Viewed by 10250 | Submission Open
Keywords: radiochemistry; radionuclide (radioisotopes); radiolabeling; radiopharmaceutical (radiotracer); nuclear medicine; theranostics (diagnostics and therapeutics); molecular imaging
(This special issue belongs to the Section Medicinal Chemistry)
Back to Nature: Pharmacological Activities of Phytochemicals Isolated from Medicinal Plants
edited by and Ludmila Yarmolinsky
submission deadline 31 Dec 2026 | 9 articles | Viewed by 10003 | Submission Open
Keywords: medicinal plant; pharmacological activity; phytochemical; disease; drug; therapeutic; polyphenol; terpene; carotenoid; saponin; alkaloid; thiophene; sugar; fatty oil; resin; phytosterol; protein; peptide; anti-inflammatory; antidiabetic; neuroprotective; anticancer; antioxidative; antimicrobial; antiviral; antifungal
(This special issue belongs to the Section Natural Products Chemistry)
Novel Neuroprotective Agents: Design, Synthesis, and Biological Evaluation submission deadline 31 Dec 2026 | 4 articles | Viewed by 9789 | Submission Open
Keywords: neurodegenerative diseases; heterocyclic compounds; rational design; enzyme inhibitors; structure–activity relationship; structural characterization
(This special issue belongs to the Section Medicinal Chemistry)
30th Anniversary of Molecules—Recent Advances in Electrochemistry submission deadline 31 Dec 2026 | 9 articles | Viewed by 9400 | Submission Open
Keywords: electrochemical science; energy conversion; charge transfer; voltammetry; magnetoelectrochemistry/spin; redox chemistry
(This special issue belongs to the Section Electrochemistry)
Chemical Analysis of Pollutant in the Environment submission deadline 31 Dec 2026 | 5 articles | Viewed by 9396 | Submission Open
Keywords: inorganic and organic pollutants; persistent organic pollutants; heavy metals; nano- and microplastics; chemical methods; instrumental methods; validation
(This special issue belongs to the Section Green Chemistry)
30th Anniversary of Molecules: Recent Advances in Photochemistry submission deadline 31 Dec 2026 | 8 articles | Viewed by 9325 | Submission Open
Keywords: organic photochemistry synthetic photochemistry; photocatalysis; photofunctionalization; photobiology; medicinal photochemistry; computational photochemistry; photoelectrochemistry; solar energy conversion; condensed and gas phase photochemistry; polymer photochemistry; supramolecular photochemistry; photochromism; luminescent sensors; photochemistry for environmental remediation
(This special issue belongs to the Section Photochemistry)
Innovative Approaches to Sustainable Wastewater Treatment—Recent Developments in Hazardous Pollutants Removal submission deadline 31 Dec 2026 | 7 articles | Viewed by 9245 | Submission Open
Keywords: wastewater treatment; industrial wastewater; physical methods; chemical methods; biological methods; emerging micropollution; dyes; heavy metals; removal; (bio)sorbent; ion exchange resin
(This special issue belongs to the Section Green Chemistry)
Chromatography—The Ultimate Analytical Tool, 3rd Edition submission deadline 31 Dec 2026 | 6 articles | Viewed by 8927 | Submission Open
Keywords: chromatography; high-performance liquid chromatography; ultra-high-performance liquid chromatography; gas chromatography; two-dimensional gas chromatography; two-dimensional liquid chromatography; paper chromatography; liquid chromatography; preparative chromatography; supercritical fluid chromatography; thin-layer chromatography
(This special issue belongs to the Section Analytical Chemistry)
Recent Advances in Porous Materials, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 8436 | Submission Open
Keywords: porous carbon; adsorption; catalysis; supercapacitor; biomass; energy storage; zeolite; fuel cell; molecular sieves; metal–organic frameworks; porous metal oxide; mesoporous silicon; macroporous resin; aerogel; separation; porous composites; covalent organic frameworks
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Developments in Biobased Polymers submission deadline 31 Dec 2026 | 5 articles | Viewed by 8423 | Submission Open
Keywords: biobased polymers; sustainability; biodegradability; polymer recycling; polymer composites; polymer processing; green chemistry
(This special issue belongs to the Section Materials Chemistry)
Bee Product Chemistry: Identification and Characterization of Natural Compounds, 2nd Edition
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 7467 | Submission Open
Keywords: honey; wax; bee pollen; venom; propolis; royal jelly; bee larvae
(This special issue belongs to the Section Natural Products Chemistry)
30th Anniversary of Molecules: Recent Advances in Organometallic Chemistry
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 7423 | Submission Open
Keywords: metal–organic framework; organometallic compounds; coordination assembly; metal–organic cluster; metal–organic cage; supramolecular chemistry
(This special issue belongs to the Section Organometallic Chemistry)
Recent Advances in Transition Metal Catalysis, 2nd Edition
edited by Dingyi Wang
submission deadline 31 Dec 2026 | 5 articles | Viewed by 7257 | Submission Open
Keywords: transition metal catalysis; photocatalysis; electrosynthesis; organic synthesis; asymmetric synthesis; C-H functionalization; C-C functionalization; C-X functionalization
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of the MOF Concept
edited by and
submission deadline 31 Dec 2026 | 4 articles | Viewed by 6822 | Submission Open
Keywords: metal–organic frameworks; gas storage and separation; catalysis; drug delivery; sensing and detection; energy applications
(This special issue belongs to the Section Organometallic Chemistry)
Emerging Trends in Microextraction Techniques for Bioanalytical Applications submission deadline 31 Dec 2026 | 4 articles | Viewed by 6073 | Submission Open
Keywords: sorbent-based microextraction (i.e., solid phase microextraction (SPME), matrix solid phase dispersion (MSPD), pipette-tip micro solid phase extraction, fabric sorptive phase extraction (FPSE), capsule phase microextraction (CPME), stir bar sorptive extraction (SBSE), etc.); liquid-phase microextraction (dispersive liquid–liquid microextraction, single-drop microextraction, electromembrane extraction, etc.); automation; new materials/sorbents (MOF, COFs, nanomaterials, conductive polymers, magnetic materials, etc.); miniaturization in sample preparation
(This special issue belongs to the Section Analytical Chemistry)
Advanced Materials for Photocatalytic and Photoelectrocatalytic Water-Splitting submission deadline 31 Dec 2026 | 2 articles | Viewed by 5812 | Submission Open
Keywords: photocatalysis; photoelectrocatalysis; water splitting; bandgap engineering; semiconductor materials; visible-light-driven catalysis
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Advances in Physical Chemistry
edited by
submission deadline 31 Dec 2026 | 9 articles | Viewed by 5694 | Submission Open
Keywords: physical chemistry; dynamics and kinetics; thermodynamics; quantum chemistry; spectroscopy
(This special issue belongs to the Section Physical Chemistry)
Applications of Agro-Industrial By-Products in Health and Beauty: Innovative Strategies and Applications submission deadline 31 Dec 2026 | 8 articles | Viewed by 5671 | Submission Open
Keywords: valorization of by-products; bioactive compounds; extraction technologies; delivery systems (micro/nano-carriers); health and skin applications
(This special issue belongs to the Section Food Chemistry)
Quantum-Chemical Studies for Superspecies—in Celebration of Professor Jean-François Gal’s 80th Birthday
edited by
submission deadline 31 Dec 2026 | 6 articles | Viewed by 5641 | Submission Open
Keywords: structure of superspecies; neutral, ionic, and/or radical forms; isomerism; electron delocalization; energetic parameters of electron transfer; thermochemistry of proton transfer; quantum-chemical studies
Interactions of Plant-Derived Foods and Medicines with the Gut Microbiome submission deadline 31 Dec 2026 | 6 articles | Viewed by 5288 | Submission Open
Keywords: anti-inflammatory effect; antimicrobial activity; fermented foods; gut metabolism; gut microbiota; herbal product; immunomodulatory effect; microbiome therapy; phytochemical; plant-based diet; postbiotics; prebiotic effect; probiotic microorganisms
Optimization of Process Methodology for Specialty and Fine Chemicals
edited by and Łukasz Lamch
submission deadline 31 Dec 2026 | 5 articles | Viewed by 5237 | Submission Open
Keywords: process optimization; specialty and fine chemicals; process intensification; numerical and statistical optimization; design of experiments; green and sustainable chemistry; chemical engineering; data driven and model-based process design
(This special issue belongs to the Section Green Chemistry)
Novel Nanomaterials for Photocatalysis submission deadline 31 Dec 2026 | 4 articles | Viewed by 4825 | Submission Open
Keywords: photocatalyst synthesis; band gap engineering; enhanced light absorption; clean energy; advanced oxidation/reduction processes; self-cleaning coatings; photocatalysis reaction mechanisms; artificial photosynthesis
(This special issue belongs to the Section Photochemistry)
Bioactive Peptides: Isolation, Identification and Application submission deadline 31 Dec 2026 | 1 articles | Viewed by 4791 | Submission Open
Keywords: peptides; proteins; hydrolysis; bioavailability; application; biological activity; food technology
(This special issue belongs to the Section Food Chemistry)
Stable Isotope Techniques Across Chemistry: Methods, Applications, and Perspectives
edited by
submission deadline 31 Dec 2026 | 5 articles | Viewed by 4491 | Submission Open
Keywords: stable isotope analysis; compound specific stable isotopes; authenticity; traceability; biogenic isotopic composition; biogeochemistry; geochemistry; molecular archaeometry; environmental chemistry
(This special issue belongs to the Section Analytical Chemistry)
Bioactive Compounds Encapsulation System: Design and Applications
edited by and
submission deadline 31 Dec 2026 | 3 articles | Viewed by 4347 | Submission Open
Keywords: bioactive compounds; encapsulation; nanocarriers; bioavailability; targeted delivery; drug delivery; functional foods
(This special issue belongs to the Section Food Chemistry)
Analytical Methods for Food and Environmental Pollutants: Current and Future Perspectives, 2nd Edition submission deadline 31 Dec 2026 | 5 articles | Viewed by 4335 | Submission Open
Keywords: emerging pollutants; food samples; environmental samples; sampling; sample preparation; analytical instrumentation; chemometric tools
(This special issue belongs to the Section Analytical Chemistry)
Advances in Trace Element Analysis: Techniques and Applications
edited by
submission deadline 31 Dec 2026 | 4 articles | Viewed by 4182 | Submission Open
Keywords: trace element analysis; speciation techniques; environmental monitoring; atomic spectrometry; mass spectrometry; chromatography; bioavailability; environmental impact
(This special issue belongs to the Section Analytical Chemistry)
30th Anniversary of Molecules—Recent Advances in Medicinal Chemistry submission deadline 31 Dec 2026 | 3 articles | Viewed by 4144 | Submission Open
Keywords: medicinal chemistry; drug discovery and development; lead compounds; proximity-inducing drugs; photopharmacology; covalent modifiers; antibody-drug conjugates; epigenetic modulators
(This special issue belongs to the Section Medicinal Chemistry)
Secondary Metabolites from Natural Products: Extraction, Isolation and Biological Activities, 2nd Edition submission deadline 31 Dec 2026 | 4 articles | Viewed by 3927 | Submission Open
Keywords: natural products; secondary metabolites; analytical techniques application; extraction and separation; chemical composition; phytochemistry; isolation and structure elucidation; secondary metabolites; antimicrobial activity; antioxidant activity; anticancer activity
(This special issue belongs to the Section Natural Products Chemistry)
Heterocyclic Molecules in Drug Discovery submission deadline 31 Dec 2026 | 3 articles | Viewed by 3555 | Submission Open
Keywords: organic synthesis of bioactive heterocyclic compounds; structural analysis of heterocycles; biological activity of heterocycles; ADME properties of heterocycles; in silico analysis and experimental analysis of heterocyclic molecules
(This special issue belongs to the Section Medicinal Chemistry)
Featured Reviews in Chemical Biology 2026
edited by and
submission deadline 31 Dec 2026 | 2 articles | Viewed by 3462 | Submission Open
Keywords: chemical biology; chemical probes; phenotypic screening; target identification/validation; bioactive metabolites; signaling molecules; drug discovery; enzymology; synthetic biology
(This special issue belongs to the Section Chemical Biology)
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