Emerging Trends in Microextraction Techniques for Bioanalytical Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 463
Special Issue Editor
Interests: pharmaceutical analytical chemistry; method development and validation; sample preparation (derivatization, microextraction, etc.); liquid and gas chromatography; capillary electrophoresis; mass spectrometry
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Special Issue Information
Dear Colleagues,
Microextraction techniques have gained significant attention from researchers working in bioanalysis due to their ability to efficiently isolate and preconcentrate analytes from complex biological matrices (e.g., blood, urine, plasma). These techniques are crucial for enhancing sensitivity and selectivity in detecting biomarkers and drugs in biological systems.
Recent trends in this field have involved the development of faster and greener and automated approaches. These aim to reduce solvent consumption, decrease sample size, and streamline the extraction process. Advances in technology have also led to the development of automated sample preparation systems, improving both efficiency and consistency. Sorbent-based or liquid-based microextraction techniques are the most promising for meeting these requirements and are increasingly replacing traditional liquid extraction approaches. Typical examples of these techniques include solid phase microextraction, stir-bar sorptive extraction, ionic-liquid-based or deep eutectic solvent-based liquid phase microextraction, microextraction by packed sorbent, micro solid phase extraction, etc.
This Special Issue focuses on the latest research trends and applications of sorbent-based and liquid-phase microextraction strategies. Researchers across all areas of basic research and biomedical sciences are cordially invited to submit a research or review article for this Special Issue.
Dr. Constantinos K. Zacharis
Guest Editor
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Keywords
- sorbent-based microextraction (i.e., solid phase microextraction (SPME), matrix solid phase dispersion (MSPD), pipette-tip micro solid phase extraction, fabric sorptive phase extraction (FPSE), capsule phase microextraction (CPME), stir bar sorptive extraction (SBSE), etc.)
- liquid-phase microextraction (dispersive liquid–liquid microextraction, single-drop microextraction, electromembrane extraction, etc.)
- automation
- new materials/sorbents (MOF, COFs, nanomaterials, conductive polymers, magnetic materials, etc.)
- miniaturization in sample preparation
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