Novel Neuroprotective Agents: Design, Synthesis, and Biological Evaluation
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2026
Special Issue Editors
Interests: medicinal chemistry; drug design and discovery; structure elucidation; anti-Alzheimer; neurodegenerative diseases; enzyme inhibitors; structure–activity relationship studies
Interests: bioactive compounds; PPAR agonists; anticancer activity; neuroprotection; antioxidants; aromatase inhibitors; NOS; small molecules; medicinal chemistry; organic synthesis
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Diseases affecting the central nervous system are becoming increasingly prevalent health problems today. Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) and Amyotrophic lateral sclerosis (ALS), can be caused by factors such as infections, oxidative stress, inflammation and mitochondrial dysfunction. Neuroprotective agents are known to play a critical role in fighting central nervous system diseases by protecting the brain from damage caused by these factors. However, more effective and safer new molecular treatment methods need to be discovered.
This Special Issue focuses on the latest research into the rational design of new neuroprotective agents, including synthesis methodologies, structural characterization studies, the evaluation of biological activities and the investigation of structure–biological activity relationships. This issue aims to provide readers in this field with an important resource by compiling scientific articles on current neuroprotective agents and laying the groundwork for the discovery and development of a new generation of neuroprotective agents.
We invite researchers to contribute to this Special Issue with research articles, short communications and reviews covering the latest approaches to the development of neuroprotective agents.
Dr. Fatih Tok
Dr. Letizia Giampietro
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegenerative diseases
- heterocyclic compounds
- rational design
- enzyme inhibitors
- structure–activity relationship
- structural characterization
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