Life | Special Issues

Regulation of Cerebrovascular Resistance in Health and Disease: From Molecules to Humans

edited by

submission deadline 13 Feb 2026 | 7 articles | Viewed by 12188 | Submission Open

Keywords: cerebral blood flow; hemodynamic forces; cerebrovascular resistance; endothelium; smooth muscle; arachidonic acid metabolites; reactive oxygen species; molecular mediators; protein and mRNA expressions; brain disease conditions; transcranial Doppler measurement; EEG; lifestyle

(This special issue belongs to the Section Physiology and Pathology)

Pain Epidemiology

edited by

Gergely Fehér

submission deadline 14 Feb 2026 | Viewed by 207 | Submission Open

Keywords: pain epidemiology; chronic pain; neuropathic pain; nociplastic pain; headache; migraine; orofacial pain; low back pain

(This special issue belongs to the Section Epidemiology)

Prebiotic Chemistry: The Molecular Origins of Life

edited by

Nigel Mason

submission deadline 15 Feb 2026 | Viewed by 690 | Submission Open

Keywords: astrobiology; astrochemistry; biochemistry; computational modelling; geochemistry; metabolic pathways; lipid formation; peptide synthesis; photochemistry; radiation chemistry; RNA world; self-assembly; systems chemistry

(This special issue belongs to the Section Origin of Life)

Microbiome Dynamics: Advancing Therapeutic Development in Health and Disease

edited by

Hoonhee Seo

, Sukyung Kim and

Md Abdur Rahim

submission deadline 16 Feb 2026 | 1 articles | Viewed by 564 | Submission Open

Keywords: next-generation probiotics (NGPs); microbiome-based therapeutics; metagenomics and multi-omics integration; microbial biomarkers; short-chain fatty acids (SCFAs); artificial human microbiome simulators; GMP-scale production; clinical translation

(This special issue belongs to the Section Microbiology)

Omics Approaches in Antipsychotic Pharmacology

edited by

Kyle Burghardt

submission deadline 18 Feb 2026 | Viewed by 100 | Submission Open

Keywords: antipsychotics; genomics; epigenomics; transcriptomics; lipidomics; metabolomics; proteomics; human; animal

(This special issue belongs to the Section Pharmaceutical Science)

Current Challenges in Human Space Flight

edited by

Larry D. Sanford

and

Richard A. Britten

submission deadline 20 Feb 2026 | 4 articles | Viewed by 14792 | Submission Open

Keywords: cognition; microgravity; sleep; stress; Martian and lunar dust; neural stem cells and progenitors

(This special issue belongs to the Section Astrobiology)

Musculoskeletal Function and Exercise Physiology: Integrative Approaches and Emerging Insights

edited by

Robert Smith

,

Tyler Neltner

,

Dimitrije Cabarkapa

and Luke Chowning

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1042 | Submission Open

Keywords: resistance exercise; aerobic exercise; sport performance; neuromuscular; electromyography; muscle function; kinematics; kinetics; biomechanics; motion analysis; imaging techniques; muscle biopsy

(This special issue belongs to the Section Medical Research)

Mucopolysaccharidosis-Plus: From Molecular Defects to Therapeutic Strategies

edited by Zuzanna Cyske

submission deadline 20 Feb 2026 | Viewed by 93 | Submission Open

Keywords: mucopolysaccharidosis; mucopolysaccharidosis-plus syndrome; MPSPS; VPS33A; therapy; patomechanism; diagnostic; patients’ care

(This special issue belongs to the Section Medical Research)

Advances in Ubiquitous Connective Tissue Architecture: Fascia, Dynamic movements and Perception in Living Structures

edited by

Jean Claude Guimberteau

submission deadline 25 Feb 2026 | 3 articles | Viewed by 10758 | Submission Open

Keywords: fascia; connective tissue; fibrillar network; microvolumes; collagen; cell microenvironment; force absorption system

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Diagnosis, Treatment and Prognosis of Prostate Cancer

edited by

Juan Gómez Rivas

and Jesús Moreno Sierra

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2814 | Submission Open

Keywords: active surveillance; hormonal treatment; personalized medicine; prostate cancer; robotic surgery; targeted therapy

(This special issue belongs to the Section Medical Research)

Nutrition, Exercise and Stress

edited by Maleah Holland-Winkler

submission deadline 25 Feb 2026 | Viewed by 547 | Submission Open

Keywords: nutrition; exercise; stress

(This special issue belongs to the Section Physiology and Pathology)

Gynecology Update: Modern Diagnostic Approaches and Innovative Therapies

edited by Szabolcs Várbíró,

Keszthelyi Márton

, Richárd Tóth and Balázs Lintner

submission deadline 26 Feb 2026 | 3 articles | Viewed by 3597 | Submission Open

Keywords: gynecologic oncology; endocrinology; reproductive medicine; fertility preservation; prevention; women’ s health innovation; quality of life; personalized therapy

(This special issue belongs to the Section Medical Research)

Conservative Management of Chronic Disease—2nd Edition

edited by

Jonathan Sinclair

submission deadline 26 Feb 2026 | 1 articles | Viewed by 1110 | Submission Open

Keywords: chronic disease; conservative management; trial protocol; clinical research; interventions

(This special issue belongs to the Section Medical Research)

Biomechanics of Aging

edited by

Márcio Fagundes Goethel

and

Filipa Sousa

submission deadline 26 Feb 2026 | Viewed by 251 | Submission Open

Keywords: aging; biomechanics; musculoskeletal; gait; balance; falls; exercise; assistive devices

(This special issue belongs to the Section Physiology and Pathology)

Skin Aging and Dermatosis

edited by Edwin Lephart and Zoe D. Draelos

submission deadline 26 Feb 2026 | Viewed by 234 | Submission Open

Keywords: skin aging; chronological dermal aging; photo-aging; hormone therapy; menopause; estrogen-deficient skin; dermatosis; skin conditions

(This special issue belongs to the Section Medical Research)

The Link Between Food Safety and Microbiology

edited by

Babak Pakbin

submission deadline 26 Feb 2026 | Viewed by 187 | Submission Open

Keywords: food safety; food microbiology; beneficial microbes; food preservation; food safety enhancement

(This special issue belongs to the Section Microbiology)

Oral Health: Microbial Dynamics and Antibiotic Stewardship

edited by

Kristina Peroš

submission deadline 26 Feb 2026 | Viewed by 136 | Submission Open

Keywords: oral health; oral microbiota; microbial dynamics; antibiotic stewardship

(This special issue belongs to the Section Microbiology)

Pharmacological Advances in Anticancer, Antiparasitic, and Immunomodulatory Therapies

edited by Cássio Santana Meira and Vinicius Pinto Costa Rocha

submission deadline 26 Feb 2026 | Viewed by 100 | Submission Open

Keywords: anticancer drugs; antiparasitic agents; immunomodulatory therapy; drug development

(This special issue belongs to the Section Pharmaceutical Science)

Acute Kidney Events in Intensive Care

edited by

Silvia De Rosa

submission deadline 27 Feb 2026 | 4 articles | Viewed by 9631 | Submission Open

Keywords: acute kidney events; ICU; critically ill; RRT; outcome; acute kidney disease; chronic kidney disease; biomarkers

(This special issue belongs to the Section Medical Research)

Novel Therapies for Chronic Inflammatory Diseases and Autoimmune Diseases

edited by

Emina Karahmet Sher

submission deadline 27 Feb 2026 | 3 articles | Viewed by 8118 | Submission Open

Keywords: chronic inflammatory diseases; autoimmune diseases; biomarker identification; innovative biologics; small-molecule inhibitors; gene editing technologies; cell-based therapeutics

(This special issue belongs to the Section Medical Research)

Feature Papers in Synthetic Biology and Systems Biology 2025

edited by

Pasquale Stano

submission deadline 27 Feb 2026 | 2 articles | Viewed by 4346 | Submission Open

Keywords: design and construction of synthetic biological systems; innovations in the creation of synthetic organisms; genetic circuits; and biomolecular devices; bottom-up synthetic biology; cell-free synthetic biology; tissue engineering and organoids; bioorthogonal parts; devices; systems; microcompartmentalized systems with soft or hard interfaces; theoretical considerations about synthetic biology; synthetic biology intersection with systems chemistry and bioorganic chemistry; computational modeling and simulation of biological processes; advances in computational tools and models that enhance our understanding of biological processes and systems; metabolic engineering and synthetic pathways; development of novel approaches for the production of biofuels; pharmaceuticals; and other valuable compounds; synthetic biology for approaching evolutionary problems; artificial evolution and in vitro evolution; optogenetics and related techniques; gene editing technologies; applications; and developments; education in synthetic and systems biology; cutting-edge techniques and applications of CRISPR and other gene editing tools; systems biology approaches to understanding complex biological networks; mathematical aspects of systems biology approaches; artificial photosynthesis; applications of synthetic biology in medicine; agriculture; and industry; practical applications of synthetic and systems biology in various sectors; including healthcare; agriculture; and industrial biotechnology; ethical; legal; and social implications of synthetic and systems biology; exploration of the broader implications of advancements in synthetic and systems biology; including ethical considerations and regulatory challenges and social implications

(This special issue belongs to the Section Synthetic Biology and Systems Biology)

Advances in Plant Biotechnology and Molecular Breeding

edited by Serik Eliby, Nikolai Borisjuk and

Yuri Shavrukov

submission deadline 27 Feb 2026 | 1 articles | Viewed by 1566 | Submission Open

Keywords: doubled haploidy; genetic engineering; genome editing; genomics; marker-assisted selection; molecular breeding; molecular markers; plant biotechnology

(This special issue belongs to the Section Plant Science)

Structure, Activity, and Function of Protein Methyltransferases: 2nd Edition

edited by

Albert Jeltsch

and

Arunkumar Dhayalan

submission deadline 27 Feb 2026 | 1 articles | Viewed by 1508 | Submission Open

(This special issue belongs to the Section Proteins and Proteomics)

Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights

edited by

Edit Dósa

submission deadline 27 Feb 2026 | 2 articles | Viewed by 1455 | Submission Open

Keywords: endovascular therapy; vascular pathophysiology; intravascular imaging; atherosclerosis; precision vascular medicine

(This special issue belongs to the Section Medical Research)

What Is Life?—2nd Edition

edited by

Jacques Fantini

and André Brack

submission deadline 27 Feb 2026 | Viewed by 403 | Submission Open

Keywords: definition of life; origins of life; artificial intelligence; alphafold; synthetic biology; theoretical biology; quantum biology; water; time; and space; membrane systems; electrostatic potential; DNA; RNA; epigenetics; mutations; molecular interactions; chirality; artificial intelligence and life processes; early evolution of life; coevolution

Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery

edited by

Alessandra Lo Cicero

submission deadline 28 Feb 2026 | 4 articles | Viewed by 16201 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers; diagnostics; cell-cell communication; drug delivery; therapeutics

(This special issue belongs to the Section Physiology and Pathology)

Recent Insights in the Pathogenesis, Diagnosis, Prognosis and Treatment of Glomerular Disorders

edited by Adrian Constantin Covic and

Gener Ismail

submission deadline 28 Feb 2026 | 8 articles | Viewed by 16194 | Submission Open

Keywords: glomerular disorders; pathology; kidney biopsy; immunology; immunosuppresion; vasculitis

(This special issue belongs to the Section Medical Research)

Clinical Manifestations and Treatment of Autoimmune Diseases: 2nd Edition

edited by

Stelvio Tonello

and

Daniele Sola

submission deadline 28 Feb 2026 | 5 articles | Viewed by 11788 | Submission Open

Keywords: autoimmunity; immunobiology; vaccine; leucocytes; immune system

(This special issue belongs to the Section Medical Research)

Atherosclerosis: Pathogenesis, Clinical Advances and Future Perspectives

edited by

Damiano D’Ardes

and

Ilaria Rossi

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5069 | Submission Open

Keywords: atherosclerosis; cardiovascular risk; hypercholesterolemia; hypertension; inflammation; cardiovascular prevention

(This special issue belongs to the Section Medical Research)

Regulation of Cellular Signaling Pathways in the Metabolic Syndrome

edited by Robert H. Newman and Danielle L. Schmitt

submission deadline 28 Feb 2026 | 4 articles | Viewed by 3572 | Submission Open

Keywords: metabolic syndrome (MetS); cellular signaling pathways; insulin signaling and resistance; nutrient-sensing pathways; inflammation and immune signaling

(This special issue belongs to the Section Physiology and Pathology)

Advances in Veterinary Infectious Diseases: Pathogenesis, Diagnostics, and Control Strategies

edited by

Hye-Mi Lee

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2824 | Submission Open

Keywords: veterinary infectious diseases; zoonoses; animal health; pathogen transmission; vaccine development; immunology; antiviral strategies; emerging pathogens; diagnostic tools; public health

(This special issue belongs to the Section Animal Science)

Advances in Novel Biomarkers and Emerging Immune/Targeted Therapies in Solid Tumors

edited by

Weijie Ma

and Liang Lu

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2578 | Submission Open

Keywords: solid tumor; biomarker; molecular targets; tyrosine kinase inhibitors (TKIs); immune checkpoint inhibitors (ICIs); oncogenic driver mutation; acquired resistance; precision oncology; cancer; next-generation sequence

(This special issue belongs to the Section Medical Research)

New Updates in Adipocytes and Adipose Tissue—3rd Edition

edited by

Kristóf Endre Károly

,

Éva Csősz

and

Rini Arianti

submission deadline 28 Feb 2026 | 1 articles | Viewed by 634 | Submission Open

Keywords: adipose tissue; obesity; inflammation; thermogenesis; adipokines; insulin resistance

(This special issue belongs to the Section Physiology and Pathology)

Decoding Hematologic Malignancies by Clinical Cytometry: From Diagnosis to Precision Medicine

edited by Yijie Liu and Huanbin Zhao

submission deadline 28 Feb 2026 | Viewed by 222 | Submission Open

Keywords: hematologic malignancies; diagnostic advancements; minimal/measurable residual disease (MRD) monitoring; emerging technologies; translational applications

(This special issue belongs to the Section Medical Research)

Structural Biology: Mechanisms, Technologies, and Insights

edited by

Mingliang Jin

,

Xiaoxuan Lin

and Hoa Nguyen

submission deadline 28 Feb 2026 | Viewed by 187 | Submission Open

Keywords: protein structure; allosteric regulation; protein dynamics; structure-guided therapeutics; structural methodology

(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)

Neuromodulation and Motor Skill Enhancement: Prospective Applications

edited by

Zachary Riley

and Davin R. Greenwell

submission deadline 28 Feb 2026 | Viewed by 151 | Submission Open

Keywords: non-invasive brain stimulation; tDCS; tACS; neuroplasticity; motor skill learning

(This special issue belongs to the Section Physiology and Pathology)

Exploring New Approaches to Disease Treatment with Attenuated Salmonella

edited by

Chamith Hewawaduge

submission deadline 28 Feb 2026 | Viewed by 106 | Submission Open

Keywords: attenuated salmonella; vaccine development; bacterial therapy; cancer immunotherapy; targeted drug delivery

(This special issue belongs to the Section Microbiology)

Germline Susceptibility and Somatic Genetic Alterations in Carcinogenesis

edited by

Jian-Hua Mao

and

Hang Chang

submission deadline 28 Feb 2026 | Viewed by 100 | Submission Open

Keywords: gene mutation; genetic susceptibility; cancer genetics; genome-wide association study; multi-omics; next generation sequencing

(This special issue belongs to the Section Physiology and Pathology)

Osteoarthritis: New Insights into Mechanisms, Diagnosis, Therapy and Management

edited by Tommaso Greco and

Carlo Perisano

submission deadline 1 Mar 2026 | 1 articles | Viewed by 670 | Submission Open

Keywords: osteoarthritis; joint degeneration; artificial intelligence; 3D printing; augmented reality; arthroplasty; joint replacement; disease-modifying therapies

(This special issue belongs to the Section Medical Research)

The Brain-Boosting Power of Exercise: Improving Cerebrovascular and Cognitive Health

edited by

Dean E. Mills

and

Edward Bliss

submission deadline 2 Mar 2026 | Viewed by 126 | Submission Open

Keywords: exercise; training; cerebrovascular; cognition; aerobic; resistance; multimodal

(This special issue belongs to the Section Physiology and Pathology)

Immune Reset and Renal Recovery: Novel Insights into Kidney Inflammation and Repair

edited by Mohanraj Sadasivam

submission deadline 13 Mar 2026 | Viewed by 204 | Submission Open

Keywords: renal immunopathology; immune reset; CAR-T-cell therapy; B-cell depletion; mRNA therapies; autoimmune kidney disease; lupus nephritis; T-cell tolerance; kidney inflammation; renal regeneration

(This special issue belongs to the Section Medical Research)

Advances in 5-Aminolevulinic Acid Applications in Medical and Healthcare

edited by Motowo Nakajima, Walter Stummer and Shun-ichiro Ogura

submission deadline 15 Mar 2026 | 5 articles | Viewed by 10562 | Submission Open

Keywords: 5-aminolevulinic acid (5-ALA); heme; protoporphyrin IX; photodynamic diagnosis; fluorescence guided surgery; photodynamic therapy; cancer metastasis; reactive oxygen species (ROS); oxide radical; heme oxygenase 1 (HO-1); NF-E2-related factor 2 (Nrf2); anti-inflammation; mitochondrial disease; diabetes; infectious disease; malaria; COVID-19

(This special issue belongs to the Section Pharmaceutical Science)

Evolutionary and Conservation Genetics: 3rd Edition

edited by

Daria Sanna

and Ilenia Azzena

submission deadline 15 Mar 2026 | 6 articles | Viewed by 9842 | Submission Open

Keywords: evolutionary genetics; population genetics; conservation genetics; phylogeography; phylogenetics; phylodynamics; molecular taxonomy

(This special issue belongs to the Section Evolutionary Biology)

Organ Predilection of Certain Gastrointestinal Diseases—Pathophysiology, Diagnosis and Management

edited by

Monjur Ahmed

submission deadline 15 Mar 2026 | 1 articles | Viewed by 3342 | Submission Open

Keywords: disease predilection in gastrointestinal tract; esophagus with certain diseases; stomach with certain diseases; duodenum with certain diseases; jejunum with certain diseases; ileum with certain diseases; colorectum with certain diseases

(This special issue belongs to the Section Physiology and Pathology)

2nd Edition—Food Microbiological Contamination

edited by

Sara Primavilla

and

Rossana Roila

submission deadline 16 Mar 2026 | 2 articles | Viewed by 1058 | Submission Open

Keywords: food safety; food microbiology; foodborne pathogens; food spoilage; food quality; food contamination; microbiological hazards; natural antimicrobials

(This special issue belongs to the Section Microbiology)

Advances in Substance Abuse and Addiction—2nd Edition

edited by

Cynthia Wei-Sheng Lee

,

Tsuo-Hung Lan

and Chieh-Liang Huang

submission deadline 18 Mar 2026 | 1 articles | Viewed by 1741 | Submission Open

Keywords: addiction medicine; opioid pharmacology; substance abuse; addictive disorder intervention

(This special issue belongs to the Section Pharmaceutical Science)

Non-Valvular Atrial Fibrillation and Acute Stroke: Prevention and Management

edited by Luca Masotti

submission deadline 18 Mar 2026 | 1 articles | Viewed by 1116 | Submission Open

Keywords: atrial fibrillation; acute ischemic stroke; intracerebral hemorrhage; direct oral anticoagulants; vitamin K antagonists; reversal therapy; tenecteplase; alteplase; intravenous thrombolysis; mechanical thrombectomy; left atrial appendage occlusion; embolic stroke of undetermined source; ECG monitoring

(This special issue belongs to the Section Medical Research)

New Insights Into Artificial Intelligence in Medical Imaging

edited by

Luigi La Via

,

Antonino Maniaci

,

Caterina Gagliano

and Salvatore Lavalle

submission deadline 20 Mar 2026 | 3 articles | Viewed by 13749 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; image analysis; precision medicine; image-guided interventions; decision support systems

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy—Third Edition

edited by

Alin Laurentiu Tatu

submission deadline 20 Mar 2026 | 3 articles | Viewed by 11168 | Submission Open

Keywords: Demodex; endosymbionts; cutaneous microbiome; integrative medicine; optical coherence tomography; dermoscopy; confocal microscopy; cutaneous comorbidities keyword; inflammatory diseases; hair; skin cancer; comorbidities; skin surgery

(This special issue belongs to the Section Physiology and Pathology)

Cereal Production Systems: Climate-Fertilizer-Crop Yield Dynamics

edited by

Lukáš Hlisnikovský

and

Veronika Zemanová

submission deadline 20 Mar 2026 | 1 articles | Viewed by 585 | Submission Open

Keywords: cereals; climate; preceding crop; fertilization; grain yield; grain quality; straw yield; soil health; soil chemistry and biology; yield stability; mineral fertilizers; organic manures; tillage

(This special issue belongs to the Section Plant Science)

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