The Brain-Boosting Power of Exercise: Improving Cerebrovascular and Cognitive Health
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: 2 March 2026 | Viewed by 19
Special Issue Editors
Interests: respiratory physiology; cognition; cerebrovascular function; exercise training
2. Centre for Health Research, University of Southern Queensland, Toowoomba, QLD 4350, Australia
Interests: cognition; cerebrovascular function; exercise training; chronic diseases; clinical biomarkers
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Special Issue Information
Dear Colleagues,
The current worldwide incidence of dementia is more than 57 million, with nearly 10 million new cases every year. Dementia is associated with adverse changes in cerebrovascular structure and function, which contribute to a decline in cognition. There are various modifiable risk factors that lead to impaired vascular function, contributing to dementia, including physical inactivity. There is increasing evidence that exercise training may help to maintain optimal cerebrovascular function and thereby prevent or slow the development of cognitive impairment. Adaptations to cerebrovascular function following exercise training may include enhanced cerebral blood flow, cerebrovascular reactivity, endothelial function, vascular changes, and neurovascular coupling, which may protect against cognitive decline and dementia. This may occur through reduced neuroinflammation and increases in neurotransmitters, neurotrophic and growth factors, and neurogenesis. Investigations researching the adaptations to cerebrovascular and cognitive function with exercise training in health and disease would support the rationale for the use of exercise as medicine to reduce the risk of dementia. These may include adaptations to aerobic, resistance, or multimodal exercise training. Therefore, the purpose of this Special Issue is to examine the impact of exercise training on cerebrovascular and cognitive function in health and disease mitigation. We welcome manuscripts and expressions of interest that have investigated this novel and emerging area of research.
Dr. Dean E. Mills
Dr. Edward Bliss
Guest Editors
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Keywords
- exercise
- training
- cerebrovascular
- cognition
- aerobic
- resistance
- multimodal
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