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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Medicine in Maternal–Fetal Care: From Cervical Insufficiency to Preterm Birth and Beyond

edited by

Moon-Il Park

submission deadline 31 Oct 2026 | 1 articles | Viewed by 1229 | Submission Open

Keywords: cervical insufficiency; preterm birth; personalized medicine; emergent cerclage; infection-controlled cerclage; maternal–fetal medicine; AI-based prediction platforms

(This special issue belongs to the Section Personalized Medical Care)

Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers

edited by Gustavo Fabregat-Cid

submission deadline 31 Oct 2026 | 1 articles | Viewed by 687 | Submission Open

Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Medicine in Obstetrics and Gynaecology

edited by

Rola Khamisy-Farah

submission deadline 31 Oct 2026 | Viewed by 472 | Submission Open

Keywords: precision medicine; reproductive health; preeclampsia; gestational diabetes; ovarian cancer; targeted therapies; endometriosis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Artificial Intelligence in Personalized Management of Cardiovascular Diseases

edited by

Dominique J. Monlezun

submission deadline 31 Oct 2026 | Viewed by 455 | Submission Open

Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy, ethics, and governance

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Management for Perioperative Anesthesia

edited by Esther A.C. Bouman

submission deadline 31 Oct 2026 | Viewed by 296 | Submission Open

Keywords: personalized anesthesia; perioperative medicine; precision pain management; artificial intelligence in anesthesia; post-procedural pain; cancer surgery; individualized risk assessment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Insights into Cardiac Electrophysiology and Personalized Medicine

edited by Ioanna Koniari

submission deadline 10 Nov 2026 | 1 articles | Viewed by 790 | Submission Open

Keywords: ablation; AF; PVI; PFA; ventricular arrhythmias; supraventricular arrhythmias; pacemakers; ICDs; CRT; conduction system pacing

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Treatments in Thoracic Oncology Surgery

edited by

Georg Schlachtenberger

and Alberto Lopez

submission deadline 15 Nov 2026 | 2 articles | Viewed by 4164 | Submission Open

Keywords: minimally invasive surgery; TNM classification; adjuvant treatment; long-term survival

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Medicine in ENT and AI

edited by Cristóbal Langdon

submission deadline 20 Nov 2026 | Viewed by 231 | Submission Open

Keywords: personalized ENT care; precision phenotyping and stratification; clinical decision support (AI-assisted); predictive modeling and outcome forecasting; real-world validation and implementation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Infectious Disease Epidemiology

edited by Cesar Henriquez-Camacho

submission deadline 25 Nov 2026 | 5 articles | Viewed by 7802 | Submission Open

Keywords: infectious diseases; epidemiology; genomics; machine learning; artificial intelligence; surveillance; vaccination; global health; stewardship programs

(This special issue belongs to the Section Epidemiology)

Cancer Biomarker and Molecular Oncology

edited by

Jeane Silva

submission deadline 25 Nov 2026 | 4 articles | Viewed by 5587 | Submission Open

Keywords: cancer biomarkers; molecular oncology; precision medicine; liquid biopsies; therapeutic resistance

(This special issue belongs to the Section Disease Biomarkers)

Precision Medicine in Hematology–Oncology: Recent Progress and Challenges

edited by Anthony M. Hunter and Nikolaos Papadantonakis

submission deadline 25 Nov 2026 | 2 articles | Viewed by 1504 | Submission Open

Keywords: oncology; hematology; precision medicine; personalized medicine; targeted therapy; molecular targets; immunotherapy

(This special issue belongs to the Section Precision Oncology)

Precision Medicine in Anesthesia and Pain

edited by Paramita Basu

submission deadline 25 Nov 2026 | Viewed by 664 | Submission Open

Keywords: Neuropeptide Y; chronic pain; NPY receptors; therapeutics; anesthesia; precision medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

New Perspectives on Personalized Treatment Strategies of Obstetrics and Gynecology Oncology

edited by

Stefano Cianci

and

Ferdinando Antonio Gulino

submission deadline 25 Nov 2026 | Viewed by 260 | Submission Open

Keywords: personalized medicine; gynecologic oncology; precision oncology; biomarkers; fertility preservation

(This special issue belongs to the Section Precision Oncology)

Personalized Medicine in Neurosurgery: Novel Perspectives and Challenges

edited by Deepti Diwan

submission deadline 25 Nov 2026 | Viewed by 222 | Submission Open

Keywords: neurological surgery; brain injury; personalized medicine; precision medicine; neuro-oncology; cerebrovascular surgery; epilepsy surgery; genomics; radiomics; artificial intelligence; image-guided neurosurgery; molecular biomarkers; translational neuroscience; neuroethics; patient-centered care

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Medicine in Critical Care Medicine: Novel Challenges and Advances

edited by

Fernando Ramasco-Rueda

submission deadline 30 Nov 2026 | 3 articles | Viewed by 23188 | Submission Open

Keywords: critical care medicine; intensive care unit (icu); perioperative medicine; precision medicine; personalized therapy; hemodynamic monitoring; biomarkers; high-risk patients; organ support; artificial intelligence in critical care; sepsis; septic shock

(This special issue belongs to the Section Personalized Medical Care)

Biomarkers and Pathogenesis of Infectious Diseases: From Research to Personalized Medicine

edited by

César Henríquez-Camacho

submission deadline 30 Nov 2026 | 3 articles | Viewed by 6750 | Submission Open

Keywords: biomarkers; infectious diseases; pathogenesis; personalized medicine

(This special issue belongs to the Section Disease Biomarkers)

Oxidative Stress and Antioxidant Therapy in Diseases

edited by

Evgenia Lymperaki

and

Ioannis Tsamesidis

submission deadline 30 Nov 2026 | 2 articles | Viewed by 6382 | Submission Open

Keywords: oxidative stress; antioxidants; ROS; diseases; antioxidants

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Therapy for Psychophysical Health: An Integrative Approach

edited by

Giada Pietrabissa

and

Giada Rapelli

submission deadline 30 Nov 2026 | 2 articles | Viewed by 4269 | Submission Open

Keywords: personalized therapy; patient-centered care; quality of life; psychosocial factors; adherence; self-management; multidisciplinary intervention; digital health tools

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Advancing Personalized Medicine in Inflammatory Disorders of the Gut

edited by Yukihiro Yamaguchi

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2292 | Submission Open

Keywords: pediatric; inflammatory bowel disease (IBD); ulcerative colitis; Crohn’s disease; Hirschsprung's disease; epigenetic; personalized; precision; precision nutrition; gut microbiota; artificial intelligence (AI)

(This special issue belongs to the Section Personalized Medical Care)

Current Trends of Precision Medicine in Oncology

edited by

Ekene E. Nweke

and

Sylvester Omoruyi

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1931 | Submission Open

Keywords: precision oncology; multi-omics; biomarkers; liquid biopsy; cancer

(This special issue belongs to the Section Precision Oncology)

Liquid Biopsy: Basic Research and Clinical Utility

edited by

Jens Claus Hahne

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1030 | Submission Open

Keywords: liquid biopsy; circulating tumour cells (CTCs); circulating tummour DNA (ctDNA); cell free DNA (cfDNA); non-coding RNAs; protein biomarker; personalised medicine

(This special issue belongs to the Section Precision Oncology)

Personalized Medicine in Hematologic Malignancies: Advances and Prospects

edited by Khalil Saleh

submission deadline 30 Nov 2026 | Viewed by 283 | Submission Open

Keywords: CAR T-cells; bispecific antibodies; antibody–drug conjugates; bispecific T-cell engagers; artificial intelligence; mechanisms of resistance; biomarkers

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Molecular and Technological Horizons in Ophthalmology: Precision Medicine from Artificial Intelligence to Optogenetic Vision Restoration

edited by

Caterina Gagliano

José Fernando Maya-Vetencourt

and

Dario Rusciano

submission deadline 30 Nov 2026 | Viewed by 266 | Submission Open

Keywords: ophthalmology; precision medicine; biomolecules; artificial intelligence; optogenetics; retinal degeneration; gene therapy; neuroprosthetics; nanocarriers; molecular diagnostics; vision restoration; oculomics

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Diagnostic Pathology: Current Status and Future Prospects

edited by

Pietro Tralongo

and

Guido Fadda

submission deadline 30 Nov 2026 | Viewed by 251 | Submission Open

Keywords: diagnostic pathology; personalized medicine; molecular pathology; digital pathology; artificial intelligence in pathology; biomarkers; histopathology; cytopathology; hematopathology; precision diagnostics; translational pathology; predictive and prognostic markers

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

Application of Medical Informatics and Knowledge-Based Ecosystem Management in Disease Diagnosis

edited by

Bernd Blobel

submission deadline 30 Nov 2026 | Viewed by 249 | Submission Open

Keywords: medical informatics; knowledge-based systems; disease diagnosis; personalized medicine; clinical decision support systems; artificial intelligence; data integration; knowledge mapping

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

Management of Cardiac Arrhythmias: Towards Personalized Management

edited by

Dimitris L. Tsiachris

submission deadline 30 Nov 2026 | Viewed by 217 | Submission Open

Keywords: atrial fibrillation; ventricular arrhythmias; antiarrhythmic drugs; catheter ablation; anticoagulants; risk stratification; stroke prevention; energy sources

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advancing Spine Surgery: Innovations in Personalized Medicine

edited by Mitchell K. Ng

submission deadline 30 Nov 2026 | Viewed by 216 | Submission Open

Keywords: personalized spine surgery; precision medicine; artificial intelligence; spine innovations; endoscopic spine surgery; degenerative spinal disorders

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Current Trends and Future Challenges in Precision Neuroimaging

edited by Chiara Gaudino and

Stefania Elena Navone

submission deadline 30 Nov 2026 | Viewed by 215 | Submission Open

Keywords: neuro-oncology; neurodegenerative disorders; ischemic and hemorrhagic stroke; head and neck pathologies

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

New Updates and Challenges in Personalized Orthopaedics

edited by Stephen M. Mcdonnell and Rahul Bhattacharyya

submission deadline 30 Nov 2026 | Viewed by 194 | Submission Open

Keywords: knee arthroscopy; knee replacement; partial knee replacement (sometimes called knee resurfacing); revision knee replacement; ACL reconstruction; hip replacement surgery; hip arthroscopy; knee replacement; knee arthroscopy

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Wearable Sensors, Machine Learning and Large Language Models for Personalized and Precision Healthcare

edited by

Iqram Hussain

submission deadline 30 Nov 2026 | Viewed by 162 | Submission Open

Keywords: wearable sensors; digital health; personalized healthcare; precision medicine; machine learning; deep learning; large language models; generative AI; artificial intelligence in healthcare; wearable signal processing (EEG, ECG, EMG, PPG, IMU); remote patient monitoring; flexible and stretchable sensors; Internet of things (IoT); smart healthcare systems; activity recognition; sleep medicine; data privacy and security; energy-efficient sensing; sustainability; digital twin; smart cities

(This special issue belongs to the Section Personalized Medical Care)

Personalized Approaches in Bladder Cancer Treatment: A Clinical and Translational Research Perspective

edited by

Vladimir Bilim

submission deadline 3 Dec 2026 | 1 articles | Viewed by 1827 | Submission Open

Keywords: bladder cancer (BC); systemic therapy; tailored therapy; immune checkpoint inhibitors; antibody–drug conjugates (ADCs); molecular targeted therapy

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Endometriosis

edited by Christine Bekos

submission deadline 10 Dec 2026 | 4 articles | Viewed by 5049 | Submission Open

Keywords: microbiome; epigenetics; fatigue; laparoscopic surgery; lifestyle changes; endometriosis

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Diagnosis and Treatment of Digestive System Disorders

edited by Gengqing Song

submission deadline 10 Dec 2026 | 1 articles | Viewed by 3820 | Submission Open

Keywords: personalized medicine; gastrointestinal disorders; precision diagnostics; functional GI disorders; gastrointestinal motility; microbiome; pharmacogenomics; gastrointestinal oncology

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Multidisciplinary Management of Acute Trauma and Emergency Surgery

edited by Oluwafemi Patrick Owodunni

submission deadline 15 Dec 2026 | 1 articles | Viewed by 1890 | Submission Open

Keywords: trauma; emergency surgery; acute care surgery; trauma systems; prehospital care; resuscitation; critical care; hem-orrhage control; damage control surgery; trauma outcomes

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Precision Medicine of Oncology Radiotherapy

edited by

Giuseppe Iatí

and Silvana Parisi

submission deadline 15 Dec 2026 | 1 articles | Viewed by 1835 | Submission Open

Keywords: novel radiotherapy approaches; novel drugs; novel diagnostic approaches; immunomodulation; omics; biomarkers; metabolic alterations; personalised medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Interventional Radiology: Towards Personalized Medicine—2nd Edition

edited by

Fabio Corvino

submission deadline 15 Dec 2026 | Viewed by 239 | Submission Open

Keywords: interventional radiology; trauma management; interventional radiology tailored to patients; interventional oncology; diagnostic and interventional radiology; image-guided biopsy

(This special issue belongs to the Section Diagnostics in Personalized Medicine)

Diagnostics and Therapeutics in Ophthalmology—2nd Edition

edited by

Yousif Subhi

submission deadline 20 Dec 2026 | 5 articles | Viewed by 18562 | Submission Open

Keywords: ophthalmology; retina; myopia; glaucoma; cataract; clinical studies; systematic reviews; meta-analyses

(This special issue belongs to the Section Evidence Based Medicine)

Depression and Anxiety: Recent Advances in Personalized Treatment and Management

edited by

Stefano Eleuteri

submission deadline 20 Dec 2026 | 3 articles | Viewed by 7160 | Submission Open

Keywords: personalized treatment; mood disorders and anxiety; treatment; therapy; depression and anxiety

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Management and Treatment in Geriatrics

edited by

Carmen da Casa

and

Juan F. Blanco

submission deadline 20 Dec 2026 | 1 articles | Viewed by 1797 | Submission Open

Keywords: geriatrics; personalized health care; artificial intelligence; comprehensive geriatric assessment; ageing; biomedical technology; health promotion; chronic disease management; rehabilitation; pharmacogenetics; neurodegenerative diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

New Approaches in Pharmacogenomics and Functional Genomics

edited by

Su-Jun Lee

submission deadline 20 Dec 2026 | Viewed by 191 | Submission Open

Keywords: personalized medicine; functional genomics; AI-driven tools; machine-learning algorithms; in silico functional prediction platforms; integrative multi-omics analyses; pharmacogenomics education program; drug response; genomic biomarker; healthcare system

(This special issue belongs to the Section Pharmacogenetics)

Personalized Medicine and Surgery in Cardiovascular Disorders

edited by

Quynh Nguyen

and Edward D. Percy

submission deadline 25 Dec 2026 | 2 articles | Viewed by 2720 | Submission Open

Keywords: precision medicine; cardiovascular disorders; cardiogenetics; translational medicine; genomic and multi-omics approaches to cardiovascular diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Urology Surgery: New Challenges and Future Perspectives

edited by

Zisis Kratiras

submission deadline 25 Dec 2026 | Viewed by 185 | Submission Open

Keywords: targeted therapy; molecular markers; minimally invasive interventions; robotic surgery; laparoscopic surgery; targeted therapy; urologic surgery

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Medicine in Cranio-Maxillo-Facial Surgery: Updates and Challenges

edited by

Sergio Olate

submission deadline 28 Dec 2026 | Viewed by 270 | Submission Open

Keywords: maxillofacial surgery; facial plastic surgery; 3D facial surgery; craniomaxillofacial surgery; precision facial treatment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Diagnosis and Treatment of Hematological Malignancies

edited by Adam S. Zayac

submission deadline 30 Dec 2026 | 1 articles | Viewed by 1958 | Submission Open

Keywords: hematologic malignancies; targeted therapies; myeloid neoplasms; non-hodgkin lymphoma; plasma cell neoplasms; supportive care; immunotherapies; cellular therapies

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Advances in Atrial Fibrillation and Cardiac Arrhythmias: Mechanisms, Diagnosis, and Therapy

edited by Antonios P. Antoniadis and

Paschalis Karakasis

submission deadline 31 Dec 2026 | 4 articles | Viewed by 7960 | Submission Open

Keywords: atrial fibrillation; arrhythmias; pathophysiological mechanisms; electrophysiological; molecular mechanisms; novel approaches; diagnosis; risk prediction; therapeutic strategies; atrial fibrillation ablation; digital health; artificial intelligence; imaging; wearable devices

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Cardiovascular and Metabolic Diseases

edited by

Gaetano Santulli

submission deadline 31 Dec 2026 | 2 articles | Viewed by 5244 | Submission Open

Keywords: cardiovascular disease; metabolic syndrome; precision health; telemedicine; biomarkers; pharmacogenomics; artificial intelligence; machine learning; epigenetics; diabetes

(This special issue belongs to the Section Mechanisms of Diseases)

Musculoskeletal Diseases: Diagnosis, Rehabilitation and Personalized Treatment

edited by

Giacomo Farì

submission deadline 31 Dec 2026 | 1 articles | Viewed by 4938 | Submission Open

Keywords: rehabilitation; regenerative medicine; telemedicine; musculoskeletal pain; sport; telemedicine; osteoarthritis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Translational Research and Novel Therapeutics in Cutaneous Melanoma

edited by Maja Tolušić Levak and Martina Mihalj

submission deadline 31 Dec 2026 | 2 articles | Viewed by 3673 | Submission Open

Keywords: cutaneus melanoma; immunopathology of melanoma; biomarkers; novel treatments; early diagnosis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Breast Cancer: New Advances in Diagnosis and Personalized Therapies

edited by Pierluigi Maria Rinaldi and Sabatino D'Archi

submission deadline 31 Dec 2026 | 5 articles | Viewed by 3588 | Submission Open

Keywords: breast cancer; Breast Imaging Reporting and Data System 3 (BI-RADS 3); imaging; radiomics; therapy; AI

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

The Ethnoracial Diversity of Diabetes: Insights into Epidemiology, Genetics, Disease Management, and Personalized Therapies

edited by

Alberto Barcelo

submission deadline 31 Dec 2026 | 1 articles | Viewed by 2168 | Submission Open

Keywords: diabetes disparities; ethnoracial diversity; genetic epidemiology; personalized therapy; health equity

(This special issue belongs to the Section Epidemiology)

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