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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Research of Precision Neuro-Oncology

edited by

Giuseppe La Rocca

submission deadline 20 Jan 2026 | 1 articles | Viewed by 2063 | Submission Open

Keywords: neuro-oncology; precision surgery; tailored treatment; innovation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Diagnosis, Treatment, and Survivorship of Lymphoma in the Era of Personalized Medicine

edited by Andrew Ip

submission deadline 20 Jan 2026 | Viewed by 191 | Submission Open

Keywords: lymphoma; non-Hodgkin lymphoma; Hodgkin lymphoma; personalized medicine; next-generation sequencing; early detection; survivorship

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

New Insights into Cardiac Electrophysiology and Personalized Medicine

edited by Ioanna Koniari

submission deadline 20 Jan 2026 | Viewed by 100 | Submission Open

Keywords: ablation; AF; PVI; PFA; ventricular arrhythmias; supraventricular arrhythmias; pacemakers; ICDs; CRT; conduction system pacing

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Medicine in Critical Care Medicine: Novel Challenges and Advances

edited by

Fernando Ramasco-Rueda

submission deadline 25 Jan 2026 | 2 articles | Viewed by 10997 | Submission Open

Keywords: critical care medicine; intensive care unit (icu); perioperative medicine; precision medicine; personalized therapy; hemodynamic monitoring; biomarkers; high-risk patients; organ support; artificial intelligence in critical care; sepsis; septic shock

(This special issue belongs to the Section Personalized Medical Care)

Advances in the Use of Machine Learning for Personalized Medicine

edited by

Josip Vrdoljak

submission deadline 25 Jan 2026 | 1 articles | Viewed by 1901 | Submission Open

Keywords: LLMs in medicine; machine learning; deep learning; drug discovery; personalized medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Dermatology: Diagnosis and Personalized Treatment

edited by Elisabeta Candrea and

Sorina Danescu

submission deadline 25 Jan 2026 | 1 articles | Viewed by 1363 | Submission Open

Keywords: biomarker; diagnostic tools; dermoscopy; ultrasound; confocal microscopy; therapeutic; personalized medicine

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Therapy for Psychophysical Health: An Integrative Approach

edited by

Giada Pietrabissa

and

Giada Rapelli

submission deadline 25 Jan 2026 | 1 articles | Viewed by 988 | Submission Open

Keywords: personalized therapy; patient-centered care; quality of life; psychosocial factors; adherence; self-management; multidisciplinary intervention; digital health tools

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Medicine in Anesthesia and Pain

edited by Paramita Basu

submission deadline 25 Jan 2026 | Viewed by 386 | Submission Open

Keywords: Neuropeptide Y; chronic pain; NPY receptors; therapeutics; anesthesia; precision medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Precision Medicine in Organ Transplantation: New Perspectives and Challenges

edited by

Tomasz Sta̧cel

submission deadline 25 Jan 2026 | Viewed by 364 | Submission Open

Keywords: organ transplantation; donor– recipient matching; immunosuppression strategies; transplant outcomes; diagnostics and perioperative care

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Dermatology

edited by

Liliana Gabriela Popa

and Calin Giurcaneanu

submission deadline 25 Jan 2026 | Viewed by 357 | Submission Open

Keywords: individualized treatment; dermatology; inflammatory skin diseases; bullous diseases; skin cancer; genodermatoses; chronic wounds

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Atrial Fibrillation: Toward Personalized Medicine

edited by

Vincenzo Mirco La Fazia

submission deadline 25 Jan 2026 | Viewed by 171 | Submission Open

Keywords: atrial fibrillation; personalized medicine; genetic predisposition; electroanatomical mapping; pulsed field ablation; genomics; substrate characterization; tailored ablation strategies

(This special issue belongs to the Section Mechanisms of Diseases)

Current Trends and Advances in Spondyloarthritis

edited by Francesca Bandinelli

submission deadline 30 Jan 2026 | 5 articles | Viewed by 17436 | Submission Open

Keywords: spondyloarthritis; ultrasound; MRI; HLA; gene; biomarkers; classification

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Advances in Oral Diseases—2nd Edition

edited by

Omar Kujan

submission deadline 30 Jan 2026 | 2 articles | Viewed by 3242 | Submission Open

Keywords: oral diseases; dental care; periodontal diseases; tooth loss; oral cancers; personalised dentistry

(This special issue belongs to the Section Epidemiology)

Advances in Infectious Disease Epidemiology

edited by Cesar Henriquez-Camacho

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3056 | Submission Open

Keywords: infectious diseases; epidemiology; genomics; machine learning; artificial intelligence; surveillance; vaccination; global health; stewardship programs

(This special issue belongs to the Section Epidemiology)

Sports Cardiology and Health Promotion Through Personalized Exercise Prescription

edited by

Luna Cavigli

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2540 | Submission Open

Keywords: sports cardiology; sports medicine; cardiomyopathies; personalized exercise prescription; cardiovascular prevention; cardiac rehabilitation; cardiopulmonary exercise test; cardiac imaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Otolaryngology: Big Data Application in Personalized Medicine

edited by

Herng-Ching Lin

and Yen-Fu Cheng

submission deadline 31 Jan 2026 | 1 articles | Viewed by 668 | Submission Open

Keywords: otolaryngology; big data; epidemiology; precision medicine; personalized medicine; head and neck cancer

(This special issue belongs to the Section Omics/Informatics)

Translational Research and Novel Therapeutics in Cutaneous Melanoma

edited by Maja Tolušić Levak and Martina Mihalj

submission deadline 31 Jan 2026 | Viewed by 352 | Submission Open

Keywords: cutaneus melanoma; immunopathology of melanoma; biomarkers; novel treatments; early diagnosis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Musculoskeletal Diseases: Diagnosis, Rehabilitation and Personalized Treatment

edited by

Giacomo Farì

submission deadline 31 Jan 2026 | Viewed by 184 | Submission Open

Keywords: rehabilitation; regenerative medicine; telemedicine; musculoskeletal pain; sport; telemedicine; osteoarthritis

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Precision Medicine in Systemic Sclerosis and Idiopathic Inflammatory Myopathies

edited by

Silvia Bellando Randone

and Lorenzo Cavagna

submission deadline 31 Jan 2026 | Viewed by 167 | Submission Open

Keywords: systemic sclerosis; idiopathic inflammatory myopathies; precision medicine; autoimmune diseases; biomarkers; genetic

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Current Clinical Practice and Future Trends of Oral and Maxillofacial Surgery

edited by Rocco Franco

submission deadline 31 Jan 2026 | Viewed by 150 | Submission Open

Keywords: oral and maxillofacial surgery; digital technology; regenerative medicine; artificial intelligence; personalized treatment.

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Orthopedics: Evolving Shoulder, Hip, and Knee Surgery Through Intelligent Technology and Personalized Clinical Care

edited by Alessandra Berton

submission deadline 31 Jan 2026 | Viewed by 102 | Submission Open

Keywords: precision orthopedics; shoulder surgery; hip surgery; knee surgery; personalized medicine; artificial intelligence; robotic surgery; 3D printing; wearable sensors; patient outcomes

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Immunotherapy and Targeted Therapy in Gynecologic Cancer: Current Status and Challenges

edited by Brigida Anna Maiorano and

Mauro Francesco Pio Maiorano

submission deadline 31 Jan 2026 | Viewed by 95 | Submission Open

Keywords: immunotherapy; targeted therapy; gynecologic cancer; vulvar cancer; biomarkers; immune checkpoint inhibitors; HPV-related tumors; personalized oncology

(This special issue belongs to the Section Molecular Targeted Therapy)

Personalized Medicine in Hematologic Malignancies: Advances and Prospects

edited by Khalil Saleh

submission deadline 31 Jan 2026 | Viewed by 64 | Submission Open

Keywords: CAR T-cells; bispecific antibodies; antibody– drug conjugates; bispecific T-cell engagers; artificial intelligence; mechanisms of resistance; biomarkers

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Complex and High-Risk Coronary Interventional Procedures

edited by

Zoltan Ruzsa

, Toth-Gayor Gabor and

Alexandru Achim

submission deadline 10 Feb 2026 | 2 articles | Viewed by 2527 | Submission Open

Keywords: complex high-risk intervention (CHIP); coronary bifurcation; coronary chronic total occlusion; severe coronary calcification; protected PCI; access site I during CHIP procedures

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Medicine in Endometriosis

edited by Christine Bekos

submission deadline 10 Feb 2026 | Viewed by 629 | Submission Open

Keywords: microbiome; epigenetics; fatigue; laparoscopic surgery; lifestyle changes; endometriosis

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Diagnosis and Treatment of Digestive System Disorders

edited by Gengqing Song

submission deadline 10 Feb 2026 | Viewed by 128 | Submission Open

Keywords: personalized medicine; gastrointestinal disorders; precision diagnostics; functional GI disorders; gastrointestinal motility; microbiome; pharmacogenomics; gastrointestinal oncology

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Application of Genetic Diagnosis in Pediatrics

edited by Avinash Veerappa

submission deadline 10 Feb 2026 | Viewed by 92 | Submission Open

Keywords: pediatric diagnosis; rare diseases; genome sequencing; exome sequencing; genetic diseases; mutations

(This special issue belongs to the Section Omics/Informatics)

The Development of Echocardiography in Heart Disease

edited by Jolanta Justina Vaskelyte, Egle Rumbinaite and Vaida Mizariene

submission deadline 20 Feb 2026 | 6 articles | Viewed by 9517 | Submission Open

Keywords: echocardiography; speckle tracking; CAD; valvular pathology; myocardial/pericardial diseases; congenital defects; rare cardiac diseases; interventional procedures

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Clinical Diagnosis and Treatment in Otorhinolaryngology

edited by Delia Hînganu and Marius Valeriu Hînganu

submission deadline 20 Feb 2026 | 4 articles | Viewed by 3328 | Submission Open

Keywords: ENT surgery; multimodality imaging; prevention; voice formation; middle ear pathology; inner ear pathology

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Management and Treatment in Geriatrics

edited by

Carmen da Casa

and

Juan F. Blanco

submission deadline 20 Feb 2026 | Viewed by 168 | Submission Open

Keywords: geriatrics; personalized health care; artificial intelligence; comprehensive geriatric assessment; ageing; biomedical technology; health promotion; chronic disease management; rehabilitation; pharmacogenetics; neurodegenerative diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Ophthalmology: Diagnosis, Prevention, and Treatment

edited by Antonio Di Zazzo and

Takenori Inomata

submission deadline 25 Feb 2026 | 1 articles | Viewed by 4350 | Submission Open

Keywords: ocular surface; dry eye disease; scleral lenses; corneal disease; keratoconus

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine in Retinal Diseases

edited by Henrik Faatz

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4136 | Submission Open

Keywords: retinal disease; age-related macular degeneration; diabetic retinopathy; gene therapy; retinal biomarker; personalized medicine; retinal imaging

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

New Insights into Personalized Care in Advance Care Planning

edited by

Mitsunori Nishikawa

submission deadline 25 Feb 2026 | 3 articles | Viewed by 2922 | Submission Open

Keywords: advance care planning; choices about future medical care; cultural differences; diversity; personalized care choices

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Novel Challenges and Advances in Pediatric Hematology and Hematologic Malignancies

edited by Katarzyna Pawińska-Wa̧sikowska

submission deadline 25 Feb 2026 | 1 articles | Viewed by 2239 | Submission Open

Keywords: pediatric hematology; hematology malignancies; therapies; diagnosis; immunotherapies; supportive care

(This special issue belongs to the Section Mechanisms of Diseases)

Precision Medicine in Gastrointestinal Neoplasms

edited by Juan Torres-Melero and

María Jose Serrano

submission deadline 25 Feb 2026 | Viewed by 432 | Submission Open

Keywords: digestive cancers; molecular biology; gastrointestinal cancers; gynecological cancers

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Precision Medicine of Oncology Radiotherapy

edited by

Giuseppe Iatí

and Silvana Parisi

submission deadline 25 Feb 2026 | Viewed by 273 | Submission Open

Keywords: novel radiotherapy approaches; novel drugs; novel diagnostic approaches; immunomodulation; omics; biomarkers; metabolic alterations; personalised medicine

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Depression and Anxiety: Recent Advances in Personalized Treatment and Management

edited by

Stefano Eleuteri

submission deadline 25 Feb 2026 | Viewed by 143 | Submission Open

Keywords: personalized treatment; mood disorders and anxiety; treatment; therapy; depression and anxiety

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Breast Cancer: New Advances in Diagnosis and Personalized Therapies

edited by Pierluigi Maria Rinaldi and Sabatino D'Archi

submission deadline 25 Feb 2026 | Viewed by 142 | Submission Open

Keywords: breast cancer; Breast Imaging Reporting and Data System 3 (BI-RADS 3); imaging; radiomics; therapy; AI

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Multidisciplinary Management of Acute Trauma and Emergency Surgery

edited by Oluwafemi Patrick Owodunni

submission deadline 25 Feb 2026 | Viewed by 139 | Submission Open

Keywords: trauma; emergency surgery; acute care surgery; trauma systems; prehospital care; resuscitation; critical care; hem-orrhage control; damage control surgery; trauma outcomes

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Cancer Biomarker and Molecular Oncology

edited by

Jeane Silva

submission deadline 27 Feb 2026 | Viewed by 102 | Submission Open

Keywords: cancer biomarkers; molecular oncology; precision medicine; liquid biopsies; therapeutic resistance

(This special issue belongs to the Section Disease Biomarkers)

Advances in Emerging Technologies for Rehabilitation: Personalized Perspective

edited by

Paweł Kiper

Błażej Cieślik

and

Agnieszka Guzik

submission deadline 28 Feb 2026 | 5 articles | Viewed by 11946 | Submission Open

Keywords: virtual reality; mixed reality; augmented reality; robotic interventions; exoskeletons; eHealth; mHealth; wearable technology; telerehabilitation; remote support; barriers and challenges of new technologies in rehabilitation; psychosocial effects of new technology interventions; insights in novel approaches in technology-supported rehabilitation; biometric technology; personalized perspective

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Application of Artificial Intelligence in Personalized Medicine: Diagnosis and Treatment

edited by Abdulkader Helwan

submission deadline 28 Feb 2026 | 2 articles | Viewed by 7107 | Submission Open

Keywords: artificial intelligence (AI); personalized medicine; precision health; AI-driven diagnostics; machine learning; deep learning; predictive analytics; genomics; proteomics; biomarkers; patient-centric care; treatment personalization; healthcare data integration; drug discovery; real-time monitoring; ethical considerations in AI; individual variability; wearable technology; health informatics

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Breast Cancer: Current Trends and Future Challenges in Evaluation and Treatment

edited by Stefano Spinaci and Giulia Ferrarazzo

submission deadline 28 Feb 2026 | 3 articles | Viewed by 6692 | Submission Open

Keywords: breast cancer; breast surgery; conservative surgery; robotic breast techniques; male breast cancer

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Clinical Progress in Personalized Management of Cardiac Surgery

edited by Chiara Tessari and Augusto D'Onofrio

submission deadline 28 Feb 2026 | 4 articles | Viewed by 3962 | Submission Open

Keywords: clinical and hemodynamic evaluation of heart valve bioprostheses and tissue engineering; clinical and hemodynamic evaluation of heart valve repair techniques; advanced heart failure and surgical treatment options; immunological evaluation in heart transplant patients; cardiovascular regenerative medicine; telemedicine and artificial intelligence application in cardiac surgery

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Atrial Fibrillation and Cardiac Arrhythmias: Mechanisms, Diagnosis, and Therapy

edited by Antonios P. Antoniadis and

Paschalis Karakasis

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1815 | Submission Open

Keywords: atrial fibrillation; arrhythmias; pathophysiological mechanisms; electrophysiological; molecular mechanisms; novel approaches; diagnosis; risk prediction; therapeutic strategies; atrial fibrillation ablation; digital health; artificial intelligence; imaging; wearable devices

(This special issue belongs to the Section Mechanisms of Diseases)

Advances in Diagnostics and Management of Respiratory System Diseases

edited by

Jun-Jun Yeh

and Chao-Tien Hsu

submission deadline 28 Feb 2026 | Viewed by 366 | Submission Open

Keywords: elderly; geriatric respiratory diseases; cardiovascular disease; metabolic disease; cancer

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Genomics and Precision Medicine

edited by

Trias Thireou

and Louis Papageorgiou

submission deadline 28 Feb 2026 | Viewed by 189 | Submission Open

Keywords: genomics; precision medicine; diagnostics; treatment; genomic test; big data; genomic screening; genomic medicine; genomic biomarker; functional genomics

(This special issue belongs to the Section Omics/Informatics)

Personalized Innovations in Integrated Breast Cancer Management

edited by

Alba Di Leone

submission deadline 28 Feb 2026 | Viewed by 160 | Submission Open

Keywords: personalized breast cancer treatment; breast surgery innovation; multidisciplinary cancer care; precision medicine; patient-centered oncology; minimally invasive breast surgery; advanced oncoplastic techniques; genomic-driven surgical planning

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Approaches in Bladder Cancer Treatment: A Clinical and Translational Research Perspective

edited by

Vladimir Bilim

submission deadline 28 Feb 2026 | Viewed by 126 | Submission Open

Keywords: bladder cancer (BC); systemic therapy; tailored therapy; immune checkpoint inhibitors; antibody– drug conjugates (ADCs); molecular targeted therapy

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Diagnosis and Treatment of Hematological Malignancies

edited by Adam S. Zayac

submission deadline 28 Feb 2026 | Viewed by 61 | Submission Open

Keywords: hematologic malignancies; targeted therapies; myeloid neoplasms; non-hodgkin lymphoma; plasma cell neoplasms; supportive care; immunotherapies; cellular therapies

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

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