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  • Article
  • Open Access
1 Citations
835 Views
15 Pages

SNAP: A Multidimensional Tool for Psychotherapeutic Process Analysis—Development and Pilot Study of Perceived Clinical Utility

  • Roberta Stanzione,
  • Chiara Scognamiglio,
  • Lucia Luciana Mosca,
  • Simona Verniti,
  • Valeria Cioffi,
  • Enrica Tortora and
  • Enrico Moretto

This paper introduces SNAP (Structure, Narrative, Activation, Process, Next), a multidimensional clinical reflection tool supporting psychotherapists in systematically attending to phenomenological, relational, and process-oriented dimensions. SNAP i...

  • Case Report
  • Open Access
256 Views
16 Pages

Distinguishing infectious collections from underlying malignancies may represent a significant diagnostic challenge, particularly when tumors present with necrotic, cystic, perforated, or abscess-like components. Here, we introduce the descriptive co...

  • Article
  • Open Access
768 Views
25 Pages

Accurate and efficient seizure detection remains a major challenge for portable EEG-based monitoring systems, where computational and power limitations restrict the use of deep learning approaches. We introduce a compact set of fourteen propagation-b...

  • Feature Paper
  • Article
  • Open Access
4,505 Views
18 Pages

Background: Generative artificial intelligence (AI) can produce realistic human faces that are shared on social media, from where younger generations often derive body image norms. Aesthetic bias in these systems may promote unrealistic standards of...

  • Article
  • Open Access
930 Views
12 Pages

University Dental Internship Mastery: From Training Evaluation to the Development of a Competency Framework: A Pilot Study

  • Hervé Becquet,
  • Carole Nagot,
  • Guillaume Savard,
  • Matthieu Renaud,
  • Nathalie Magneron and
  • Frédéric Denis

Background: A training program for University Internship Supervisors in Dentistry (UISD) was created from scratch in 2022 at the Faculty of Dentistry in Tours. Designed to prepare practitioners for the role of UISD, it is structured into three distin...

  • Article
  • Open Access
1,365 Views
7 Pages

A Physiological, Non-Cannulated CT–Dacryocystography Protocol Using Dropwise Iodixanol Instillation: A Pilot Study

  • Flavio Cassano,
  • Giovanni Leo Tomacelli,
  • Costa Maria Carmela,
  • Besozzi Gianluca,
  • Rizzo Tiziana,
  • Paladini Adriana and
  • Guglielmo Sticchi

Background: Conventional CT–dacryocystography (CT-DCG) requires canalicular cannulation and forced contrast injection, which may distort anatomy and cause discomfort. This study describes a non-cannulated CT-DCG protocol using dropwise iodixano...

  • Case Report
  • Open Access
574 Views
6 Pages

Ossification of the vascular pedicle following fibula free flap (FFF) reconstruction is an uncommon and typically asymptomatic complication. Symptomatic cases requiring intervention are rare. We report a 29-year-old man with anterior maxillary osteos...

  • Editorial
  • Open Access
1,790 Views
2 Pages

The current challenge for scientists, regardless of their research field or area of activity, consists in presenting the evidence emerging from studies carried out at the local, national, or even international level to the public and decision makers...

  • Perspective
  • Open Access
614 Views
23 Pages

Perspectives on the Appropriate Management of Patients with Hepatocellular Carcinoma (HCC): Updates from the “Salerno 2025 Interdisciplinary Consensus Conference” on Diagnostic Paths and Follow-Up of HCC

  • Marcello Persico,
  • Francesco Sabbatino,
  • Pietro Torre,
  • Mario Masarone,
  • Luciano Tarantino,
  • Gaetano Gargiulo,
  • Ferdinando Costabile,
  • Davide Ferdinando Precone,
  • Antonella Cavalli and
  • Prisco Piscitelli
  • + 4 authors

The new therapeutic options now available for patients with hepatocellular carcinoma (HCC) have made their assessment more complex, especially due to the different stages of liver cirrhosis typically associated with this tumor. The management of the...

  • Article
  • Open Access
578 Views
22 Pages

The development of precise quantitative metrics is essential for characterizing the response of biological systems to external perturbations, enabling a transition from qualitative observation to predictive modeling. In this context, mathematical fra...

(This article belongs to the Special Issue Innovative Therapeutic Strategies in Cancer: From Molecular Targets to Drug Development)
  • Article
  • Open Access

OMICS Sciences: toward omics personalized medicine

  • Michele Maffia,
  • Luana Conte,
  • Marco Greco,
  • Maria Chiara Maffia,
  • Pasquale Simeone and
  • Daniele Vergara

The omics sciences of systems biology including genomics, transcriptomics, lipidomics, metabolomics, and proteomics, aim at understanding the biological mechanisms that give rise to the phenotype of an organism by using high-throughput technologies w...

  • Article
  • Open Access

Mitochondria of spermatozoa significantly differ, structurally and functionally, from the corresponding organelles of somatic cells. Nevertheless, sperm mitochondria, as well as the somatic ones, are the location of the oxidative phosphorylation (OXP...

  • Article
  • Open Access

Experimental research in this area focuses, in a section of the laboratory of Neurosciences, on new technologies applied to Cognitive Neuroscience and Psychophysiology. The aim of this paper will be highlighting the link between basic research and in...

  • Article
  • Open Access

Semiautomatic segmentation of glioblastoma for radiotherapy treatment plannin

  • Giorgio De Nunzio,
  • Benedetta Tafuri,
  • Marina Donativi,
  • Marta Vannini,
  • Lorenzo Mazzoni,
  • Giovanni Rubino,
  • Antonella Castellano and
  • Luigi Pirtoli

During the radiation therapy (RT) process, the treatment is planned and simulated with a treatment planning system (TPS). Contouring identifies the Planning Treatment Volume (PTV), that is the physical RT treatment volume. PTV of Glioblastoma (GB) in...

  • Article
  • Open Access

Transformed Follicular Lymphoma: Not all fit in one

  • Vittoria Tarantino,
  • Luana Conte,
  • Martina Manni,
  • Alessandra Dondi,
  • Monica Bellei and
  • Massimo Federico

Follicular Lymphoma (FL) is the second most frequent non-Hodgkin lymphoma accounting for approximately 10-20% of all lymphomas in Western Countries. Histologic transformation (HT) is a frequent event in the clinical course of patients with indolent l...

  • Article
  • Open Access

The Obstructive Sleep Apnea (OSA) is becoming a significant problem nowadays because it is associated with an increasing cardio-metabolic mortality. This disorder is increasing dramatically in the western world because it related to obesity. The cost...

  • Article
  • Open Access

First evaluation of the ASL of Lecce mammographic screening program results by using Surgical Pathology’s indicators of quality in diagnosis and treatment

  • Carlo Olla Atzeni,
  • Ermenegildo Colosimo,
  • Denise Casella,
  • Erika Delos,
  • Maria Piera Mano,
  • Anna Melcarne,
  • Mariano Tomatis,
  • Massimo Torsello,
  • Antonio Ponti and
  • Enrico D’Ambrosio

The aim is to highlight the progress of earliness and quality of diagnosis and breast cancer cure in the Province of Lecce by surveying a number of indicators obtainable from surgical pathologist’s evaluation. The study, conducted with the software S...

  • Article
  • Open Access

Reflectance Confocal Microscopy in Melanoma and Non-melanoma Skin Cancer

  • Francesca Farnetani,
  • Luana Conte,
  • Gian Luca Cervo,
  • Massimo Federico and
  • Giovanni Pellacani

Reflectance confocal microscopy (RCM) is a new technique enabling the visualization of the skin at a quasi-histological resolution, allowing the identification of clues for the diagnosis of skin diseases. The aim of this anal-ysis was to provide new...

  • Article
  • Open Access

COPD is often accompanied by other chronic diseases that are also associated with systemic inflammation, such as obesity, diabetes, and arteriosclerosis. Recent data indicate that nocturnal oxygen desaturation and coexisting metabolic syndrome are re...

  • Article
  • Open Access

Vaginal infections in diabetic woman

  • Davide Carati,
  • Giuliana Conversano,
  • Roberta Stefanizzi,
  • Antonio Malvasi,
  • Domenico Baldini,
  • Sarah Gustapane and
  • Andrea Tinelli

Diabetes mellitus is a chronic disease that can affect any organ or system of the body. Diabetes mellitus has long been considered as one of the factors causing Candida vaginitis and has the potential to affect sexual function in women. Infectious di...

  • Article
  • Open Access

Developmental phonological dyslexia and dysgraphia in a regular orthography: a case study

  • Chiara V. Marinelli,
  • Anna Putzolu,
  • Marinella De Salvatore,
  • Marika Iaia and
  • Paola Angelelli

In the Italian language the phoneme-to-grapheme mapping is fairly regular so that children are able to master very early reading and spelling skills. However, persisting phonological spelling deficits, were recently described in a sub-group of Italia...

The OMICS role in the early diagnosis of OSA

  • Luana Conte,
  • Marco Greco,
  • Domenico Maurizio Toraldo,
  • Michele Arigliani,
  • Michele Maffia and
  • Michele De Benedetto

Obstructive sleep apnea (OSA) syndrome is a condition characterized by the presence of complete or partial collapse of the upper airways during sleep, resulting in fragmentation of sleep associated with rapid episodes of intermittent hypoxia (IH) and...

  • Article
  • Open Access

Can graph theory discriminate between aptamer-protein configurations?

  • Emanuela Cianci,
  • Rosella Cataldo and
  • Eleonora Alfinito

Graph theory has been extensively applied in the study of proteins, although few applications still exist on biomolecules like aptamer-protein complexes, whose structure is in silico obtained. Aptamers represent a challenging field of research, espec...

  • Article
  • Open Access

Can an ECG help prevent sudden death in young people?

  • Marcello Costantini,
  • Massimo Trianni,
  • Giuseppina De Benedittis,
  • Cristina Tritto,
  • Lorenzo Costantini,
  • Luana Conte,
  • Marco Greco,
  • Michele Maffia and
  • Michele De Benedetto

A wide spectrum of diseases or conditions (genetically based or acquired), in the presence of triggering elements, can lead to arrhythmic events, having sudden death as a common result. The substrate of fatal arrhythmia de-pends on age: over 35 years...

  • Article
  • Open Access

Diagnosis and management of prolonged second stage of labor and its complications is difficult and often poses a dilemma to the treating obstetrician regarding timing and type of intervention. Nowadays, the diagnosis of dys-tocic prolonged second sta...

  • Article
  • Open Access

At the beginning, it was the French philosopher Michel Foucault who explicitly defined medicine as a matter of biopolitics, making evident the role that, in his opinion, medical knowledge assumed in certain strategies of pow-er. Starting from this as...

  • Article
  • Open Access

Postpartum Hemorrage: Are There Physiological Mechanisms of Prevention?

  • Antonio Belpiede,
  • Antonio Malvasi,
  • Michael Stark and
  • Andrea Tinelli

The postpartum hemorrhage (PPH) it is one of the worst complications of the pregnant woman and the leading cause of maternal mortality in the world, as it produces potentially catastrophic effects on patients, with high morbidity and morbidity. Likew...

Obstructive Sleep Apnea (OSA), an emerging health problem

  • Luana Conte,
  • Domenico Maurizio Toraldo,
  • Michele Mariano Arigliani,
  • Marco Greco,
  • Michele Maffia and
  • Michele De Benedetto

Obstructive Sleep Apnea (OSA) is the most common respiratory disorder in Western societies: according to a first recent worldwide epidemiological study, it was estimated that 936 million patients aged 30-69 years with mild to moderate OSA and 425 mil...

  • Article
  • Open Access

The Phonetics of Speech Production and Medical Research

  • Barbara Gili Fivela,
  • Mirko Grimaldi,
  • Francesco Sigona and
  • Sonia d’Apolito

The production of speech requires the interplay of a number of cognitive and motoric activities, which make it an interesting object of study from both a linguistic and a medical point of view. In this paper, we discuss, first, the features and domai...

  • Article
  • Open Access

Overweight and obesity in paediatric population are becoming serious public health problems, reaching epidemic proportions in the world and being recognized as the “new pandemic of the twenty first century”. Food choices and nutritional habits are st...

Attitudes, knowledge and Practices of Nurses towards HIV/AIDS Patients. An Observational, Cross Sectional, Multicenter study

  • Maria Chiara Carriero,
  • Fabiana Stella,
  • Roberto Lupo,
  • Antonino Calabrò,
  • Cosimo Petrelli,
  • Ilenia Pareo,
  • Marco Rizzo,
  • Maicol Carvello,
  • Valeria Archetta and
  • Luana Conte

Background. Attitudes, knowledge and practices of nurses towards HIV/AIDS patients are of continuous in-terest, especially in developing countries. However, in Italy, this topic is still scarcely debated. Materials and methods. An observational, cros...

Monitoring Water Quality Using Plankton as Biosensor

  • Vito P. Pastore,
  • Thomas Zimmerman,
  • Sujoy K. Biswas and
  • Simone Bianco

In this paper we establish a baseline to use Stentor coeruleus, a freshwater single cell ciliate, as a chemical biosensor. We expose Stentor to an array of chemical species and concentration and monitored morphological and dynamic responses. We devel...

  • Article
  • Open Access

CESAREAN MYOMECTOMY TECHNIQUE: A CRITICAL REVIEW

  • Marina Vinciguerra,
  • Radmila Sparic,
  • Safak Hartinaz,
  • Giuseppe Trojano and
  • Andrea Tinelli

Background: Cesarean myomectomy (CM) is, for many gynecologists, a discussed surgical procedure character-ized by fibroid’s removal during cesarean section (CS) followed by possible complications. For a long time, it has been common and shared thinki...

  • Article
  • Open Access

Training Teachers as Health Promoters

  • Manuela Pulimeno,
  • Prisco Piscitelli,
  • Alessandro Miani,
  • Annamaria Colao and
  • Salvatore Colazzo

In the context of the global changes that affect families and communities, including the current COVID-19 pan-demic, today’s young people face new threats to their health and most of them lack adequate nutrition, healthcare services and education. As...

The mechanobiology of the nucleus

  • Marina Damato and
  • Michele Maffia
J. Interdiscip. Res. Appl. Med.2020, 4(2), 7-14;https://doi.org/10.1285/i25327518v4i2p7 
(registering DOI)

31 December 2020

In addition to biochemical and molecular signals coming from the microenvironment, cells are able to sense and integrate mechanical stresses, additional fundamental regulators of cell behaviour. Emerging demonstrations in-dicate that mechanical cues...

Domestic violence is characterized by coercive actions of various kinds (psychological, physical, sexual and eco-nomic) that persist over time; the chronicity of these same actions implies the development of short, medium and long term consequences t...

  • Article
  • Open Access
1,020 Views

Prevention Strategy of Intrauterine Adhesions: update and future perspective

  • Sarah Gustapane,
  • Sara Cavalera,
  • Ottavia D’Oria and
  • Andrea Tinelli

Intrauterine adhesions (IUAs) caused by endometrial injury have a serious impact on women’s fertility and mor-bility and involves a wide range of patients. Although the first case of IUAs was published in 1984 by Heinrich Fritsch, a full description...

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J. Interdiscip. Res. Appl. Med. - ISSN 2532-7518