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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Arterial Stiffness: A Key Determinant of Cardiovascular Risk in Clinical Medicine

edited by Hack-Lyoung Kim

submission deadline 20 Oct 2026 | Viewed by 309 | Submission Open

Keywords: cardiology; cardiovascular medicine; arterial stiffness; pulse wave velocity; central hemodynamics; vascular aging; hypertension; atherosclerosis; arteriosclerosis; cardiovascular risk stratification

(This special issue belongs to the Section Cardiology)

Maternal–Fetal Medicine: Clinical Updates and Perspectives

edited by

Uri Amikam

and Hadas Miremberg

submission deadline 20 Oct 2026 | Viewed by 300 | Submission Open

Keywords: preterm labor; hypertensive disorders of pregnancy; fetal growth restriction; gestational diabetes; multiple pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Personalized Medicine in Psychiatry: Precision Approaches to Diagnosis and Treatment

edited by Simran Maggo

submission deadline 20 Oct 2026 | Viewed by 299 | Submission Open

Keywords: pharmacogenomics; precision medicine; precision psychiatry; pharmacogenomic testing; pharmacogenomic bioinfor-matics

(This special issue belongs to the Section Mental Health)

Optimizing Post-Return of Spontaneous Circulation (Post-ROSC) Management for Out-of-Hospital Cardiac Arrest (OHCA): Strategies to Enhance Survival, Neurological Recovery, and Social Reintegration

edited by

Enrico Baldi

submission deadline 20 Oct 2026 | Viewed by 291 | Submission Open

Keywords: return of spontaneous circulation (ROSC); quality of life; psychological distress; post-ROSC management; return to society

(This special issue belongs to the Section Cardiology)

Clinical Highlights and Digital Evolution in Trauma and Orthopedic Surgery

edited by

Francesca Veronesi

and

Deyanira Contartese

submission deadline 20 Oct 2026 | Viewed by 285 | Submission Open

Keywords: trauma surgery; orthopedic surgery; musculoskeletal trauma; joint reconstruction; minimally invasive techniques; surgical innovation; implant technology; sports injuries; evidence-based orthopedics; clinical translational research; digital surgery; research reproducibility

(This special issue belongs to the Section Orthopedics)

Clinical Insights into New Therapeutic Strategies of Atrial Fibrillation

edited by

Giulia Massaro

and

Cristian Martignani

submission deadline 20 Oct 2026 | Viewed by 285 | Submission Open

Keywords: atrial fibrillation; rhythm control; catheter ablation; pulsed field ablation; stroke prevention; anticoagulation strategies; left atrial appendage closure; wearable technologies; artificial intelligence in cardiology; precision medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Technological Advances and Innovations in Spine Surgery

edited by

Jared D. Ament

submission deadline 20 Oct 2026 | Viewed by 283 | Submission Open

Keywords: neurosurgery; spine surgery; lumbar spine; lumbar spondylolisthesis; artificial disk/artificial facet replacement; motion preservation; patient-specific implants; enabling technologies; use of AI

(This special issue belongs to the Section Clinical Neurology)

Recent Updates in Minimally Invasive Surgery

edited by Simona Parisi and

Giovanni Conzo

submission deadline 20 Oct 2026 | Viewed by 253 | Submission Open

Keywords: mini-invasive surgery; robotic surgery; patient compliance; mini-invasive diagnostic procedures; patient comfort

(This special issue belongs to the Section General Surgery)

Clinical Advances in Radiation Treatment of Head and Neck Cancers

edited by Daniela Dumitrescu,

Eugen Osiac

and Dragoș-Ovidiu Alexandru

submission deadline 20 Oct 2026 | Viewed by 250 | Submission Open

Keywords: head and neck cancer; radiation therapy; IMRT and VMAT; Image-guided and adaptive radiotherapy; CT, MRI, and PET imaging; post-radiotherapy response assessment; radiation-induced toxicity; skin and mucosal toxicity; dental, maxillofacial, and reconstructive complications; multimodal oncologic treatment

(This special issue belongs to the Section Nuclear Medicine & Radiology)

A New Era of Myalgic Encephalomyelitis (ME) Evolving from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

edited by

Kunihisa Miwa

submission deadline 20 Oct 2026 | Viewed by 245 | Submission Open

Keywords: myalgic encephalomyelitis; chronic fatigue syndrome; post-exertional malaise; central nervous system; neuroinflammation; orthostatic intolerance; disequilibrium; neuroimmune disorder

(This special issue belongs to the Section Clinical Neurology)

Advances in Mapping and Catheter Ablation of Ventricular Tachycardia

edited by

Michele Magnocavallo

Pietro Rossi

Filippo Maria Cauti

, Antonio Bisignani and Stefano Bianchi

submission deadline 20 Oct 2026 | Viewed by 243 | Submission Open

Keywords: catheter ablation; ventricular tachycardia; sudden cardiac death; structural heart disease

(This special issue belongs to the Section Cardiology)

State of the Art: Updates in Preterm Labor and Preterm Birth—2nd Edition

edited by

Eran Bornstein

and Moti Gulersen

submission deadline 20 Oct 2026 | Viewed by 243 | Submission Open

Keywords: prenatal diagnosis; fetal neurosonography; detection of fetal anomalies in the first trimester; preterm birth; antenatal corticosteroids; cerclage; mutiple gestations

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Perspectives and Emerging Insights in Urological Cancer

edited by

Ilias Giannakodimos

and

Konstantinos Stravodimos

submission deadline 20 Oct 2026 | Viewed by 240 | Submission Open

Keywords: prostate cancer; renal cancer; bladder cancer; urogenital cancer; urological cancer; biopsy; diagnosis; therapy

(This special issue belongs to the Section Nephrology & Urology)

Best Practices in Kidney Transplantation Across the Continuum: Evaluation to Graft Failure

edited by Sami Alasfar

submission deadline 20 Oct 2026 | Viewed by 238 | Submission Open

Keywords: kidney transplantation; allograft rejection; biomarkers; immunosuppression; failing allograft; retransplantation; transplant outcomes

(This special issue belongs to the Section Nephrology & Urology)

Clinical Blood Transfusion: History, Development, Need, Demand and Use

edited by

Cees Th Smit Sibinga

submission deadline 20 Oct 2026 | Viewed by 237 | Submission Open

Keywords: clinical blood transfusion; quality management; demands; needs; uses

(This special issue belongs to the Section Hematology)

Clinical Translational Electrophysiology and Therapeutic Innovation in Cardiovascular Disease

edited by Mena Abdelsayed

submission deadline 20 Oct 2026 | Viewed by 236 | Submission Open

Keywords: cardiac electrophysiology; arrhythmias; translational cardiology; hiPSC-derived cardiomyocytes; lon channels; precision medicine; drug repurposing; computational modeling; neuromodulation; mechanobiology; digital twins

(This special issue belongs to the Section Cardiovascular Medicine)

Cardiogenic Shock: New Insights into Diagnosis, Management and Prognosis

edited by Faisal Rahman

submission deadline 20 Oct 2026 | Viewed by 233 | Submission Open

Keywords: cardiogenic shock; patient outcomes; mechanical circulatory support; hemodynamics; care disparities; healthcare

(This special issue belongs to the Section Cardiology)

Spinal Cord Injury in Elderly People: Prevention of Complications

edited by Vaidyanathan Subramanian

submission deadline 20 Oct 2026 | Viewed by 231 | Submission Open

Keywords: spinal cord injury; demography; morbidities; complications; spinal injuries; patients; family members; caregivers; general practitioners; discharge; elderly

(This special issue belongs to the Section Geriatric Medicine)

Procedural Planning in Congenital Heart Disease

edited by Reza Ashrafi and Sarah Moharem-Elgamal

submission deadline 20 Oct 2026 | Viewed by 212 | Submission Open

Keywords: congenital heart disease; CPEX; echocardiography; CT; MRI; procedural planning

(This special issue belongs to the Section Cardiology)

Musculoskeletal Radiology: Advances and Innovations in Sports Medicine

edited by

Apostolos Karantanas

Michail Klontzas

and Evangelia E. Vassalou

submission deadline 20 Oct 2026 | Viewed by 211 | Submission Open

Keywords: musculoskeletal radiology; sports injury diagnosis and management; quantitative magnetic resonance imaging (MRI); imaging biomarkers in orthopedic medicine; artificial intelligence in sports imaging; image-guided musculoskeletal interventions; post-traumatic osteoarthritis assessment

(This special issue belongs to the Section Sports Medicine)

Oral and Maxillofacial Surgery: Current Trends, Innovations and Techniques

edited by Gabriel Armencea and

Florin Onisor

submission deadline 21 Oct 2026 | 2 articles | Viewed by 3845 | Submission Open

Keywords: maxillofacial; trauma; deformities; cleft lip and palate; OMF surgery; head and neck; head and neck oncology; orthognathic surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

State-of-the-Art Innovations in Oral and Maxillofacial Surgery: 2nd Edition

edited by Marcin Kozakiewicz and

Tomasz Wach

submission deadline 22 Oct 2026 | 4 articles | Viewed by 2428 | Submission Open

Keywords: oral surgery; maxillofacial surgery; traumatology; orthognatic surgery; infections; oncology; diagnostics; treatment; implantology; augmentation; imaging; computer-assisted techniques

(This special issue belongs to the Section Otolaryngology)

Advancing Minimally Invasive Spine Surgery: A Special Edition on Endoscopic Spine Surgery

edited by

Adham M. Khalafallah

and Gregory W. Basil

submission deadline 23 Oct 2026 | 9 articles | Viewed by 20885 | Submission Open

Keywords: minimally invasive spine surgery (MIS); endoscopic spine surgery (ESS); spine surgery; percutaneous spine surgery; full-endoscopic spine surgery; biportal endoscopic spine surgery (BESS); unilateral biportal endoscopy (UBE); percutaneous endoscopic lumbar discectomy (PELD); endoscopic decompression; transforaminal endoscopic lumbar discectomy (TELD); interlaminar endoscopic lumbar discectomy (IELD); endoscopic lumbar fusion; endoscopic transforaminal lumbar interbody fusion (Endo-TLIF)

(This special issue belongs to the Section Clinical Neurology)

Clinical Research in Macular Degeneration and Other Retinal Diseases

edited by

Seong Joon Ahn

submission deadline 23 Oct 2026 | 2 articles | Viewed by 1247 | Submission Open

Keywords: macular degeneration; retinal diseases; clinical research; retinal imaging; real-world data; drug-induced retinal toxicity; epidemiology; screening strategies

(This special issue belongs to the Section Ophthalmology)

Clinical Updates in Physiotherapy for Musculoskeletal Disorders: 2nd Edition

edited by

Santiago Navarro Ledesma

submission deadline 23 Oct 2026 | 1 articles | Viewed by 1109 | Submission Open

Keywords: musculoskeletal disorders; physiotherapy interventions; lifestyle; psychoneuroimmunology; chronic pain, inflammation; physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in Anesthesia and Critical Care

edited by Vincenzo Russotto and

Giuseppe Accurso

submission deadline 23 Oct 2026 | 1 articles | Viewed by 755 | Submission Open

Keywords: anesthesia; critical care; perioperative critical care; emergency medicine; prehospital emergency care; infectious diseases in critical care; antimicrobial stewardship; sepsis

(This special issue belongs to the Section Intensive Care)

Advances in Spine Surgery: Current Innovations and Future Directions

edited by

Gonzalo Mariscal

and Jesús Burgos

submission deadline 24 Oct 2026 | 5 articles | Viewed by 4551 | Submission Open

Keywords: spine; clinical studies; robotics; minimally invasive; complications; patient-reported outcomes; reviews

(This special issue belongs to the Section Orthopedics)

Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition

edited by

Antonella Polimeni

and

Iole Vozza

submission deadline 25 Oct 2026 | 14 articles | Viewed by 37987 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Diabetes, Obesity, and Hypertension

edited by

Piotr Matłosz

and

Justyna Wyszyńska

submission deadline 25 Oct 2026 | 11 articles | Viewed by 20938 | Submission Open

Keywords: obesity; hypertension; diabetes; lifestyle; physical activity; risk factors

(This special issue belongs to the Section Endocrinology & Metabolism)

Hand Surgery: Latest Advances and Prospects

edited by

Camillo Fulchignoni

and Lorenzo Rocchi

submission deadline 25 Oct 2026 | 9 articles | Viewed by 16468 | Submission Open

Keywords: hand surgery; musculoskeletal and nerve disorders; innovative surgical procedures; minimally invasive techniques; rehabilitation strategies; robotic surgery

(This special issue belongs to the Section Orthopedics)

Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

edited by

Joaquín Moya-Angeler

and

Francisco Forriol

submission deadline 25 Oct 2026 | 8 articles | Viewed by 15298 | Submission Open

Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Autoimmune Skin Diseases: Innovations, Challenges, and Opportunities

edited by Shany Sherman

submission deadline 25 Oct 2026 | 6 articles | Viewed by 13229 | Submission Open

Keywords: healthcare utilization; inflammatory skin diseases; photodermatoses; collagen vascular disease; immunobullous disorders; graft-versus-host disease

(This special issue belongs to the Section Dermatology)

Recent Developments in Reproductive Endocrinology

edited by Birute Žilaitiené and Jonas Čeponis

submission deadline 25 Oct 2026 | 3 articles | Viewed by 11729 | Submission Open

Keywords: hypogonadism; infertility; sex hormone deficiency; reproductive endocrinology; sexual health; assisted reproduction

(This special issue belongs to the Section Endocrinology & Metabolism)

Novel Insights into Neonatal Intensive Care

edited by

Vasilios Giapros

and Maria Baltogianni

submission deadline 25 Oct 2026 | 5 articles | Viewed by 11045 | Submission Open

Keywords: neonatology; neonatal intensive care; neonate; sepsis; nutrition; ventilation; hemodynamic; neurodevelopment

(This special issue belongs to the Section Clinical Pediatrics)

Advances in the Diagnosis and Treatment of Skin Cancer

edited by

Konstantinos Lallas

and

Aimilios Lallas

submission deadline 25 Oct 2026 | 6 articles | Viewed by 10007 | Submission Open

Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis

(This special issue belongs to the Section Oncology)

Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases

edited by Madalina Ilie and

Mihai Ciocîrlan

submission deadline 25 Oct 2026 | 5 articles | Viewed by 6419 | Submission Open

Keywords: esogastric lesions; pancreatic diseases; colorectal lesions; hepatobiliary diseases; optical endoscopy; endoscopic ultrasound; upper and lower endoscopy; endoscopic retrograde cholangiopancreatography

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endometriosis and Endometrial Cancer: Challenge and Clinical Management

edited by

Bogdan Obrzut

, Tomasz Kluz and Bernhard Krämer

submission deadline 25 Oct 2026 | 2 articles | Viewed by 6400 | Submission Open

Keywords: endometriosis; endometrial cancer; non-invasive diagnosis; molecular profiling; surgical techniques; medical treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Emerging Surgical Techniques in the Management of Urological Diseases

edited by

Riccardo Lombardo

submission deadline 25 Oct 2026 | 3 articles | Viewed by 5783 | Submission Open

Keywords: minimally invasive; robotics; partial nephrectomy; radical prostatectomy; focal therapy; benign prostatic hyperplasia; prostate cancer; bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Knee Arthroplasty

edited by

Sang-Hoon Park

submission deadline 25 Oct 2026 | 6 articles | Viewed by 5588 | Submission Open

Keywords: knee surgery; knee arthroplasty; knee joint replacement; osteoarthritis; knee arthritis

(This special issue belongs to the Section Orthopedics)

New Advances in the Management of Voice Disorders: 2nd Edition

edited by

Ben Barsties v. Latoszek

submission deadline 25 Oct 2026 | 5 articles | Viewed by 5475 | Submission Open

Keywords: voice disorders; laryngology; laryngoscope; acoustic analysis; dysphonia; voice surgery; diagnosis; treatment; rehabilitation; vocal folds; voice assessment/measures

(This special issue belongs to the Section Otolaryngology)

New Advances in Cleft Lip and Palate and Facial Plastic Surgery

edited by

Michael Schwaiger

, Wolfgang Zemann and Rainer Lutz

submission deadline 25 Oct 2026 | 3 articles | Viewed by 5009 | Submission Open

Keywords: cleft lip repair; rhinoplasty; secondary rhinoplasty; cleft rhinoplasty; facial plastic surgery; nasolabial area; upper lid surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

New Clinical Advances in Psoriasis and Psoriatic Arthritis: 2nd Edition

edited by

Diego Orsini

and Alessandra Narcisi

submission deadline 25 Oct 2026 | 3 articles | Viewed by 4159 | Submission Open

Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; inflammatory autoimmune disease; immunotherapy; autoimmunity; comorbidities; therapeutic; diagnosis; treatment; management; biologics

(This special issue belongs to the Section Dermatology)

Sarcoma—Clinical Updates: 2nd Edition

edited by

Julia Visgauss

submission deadline 25 Oct 2026 | 3 articles | Viewed by 3468 | Submission Open

Keywords: sarcoma; osteosarcoma; ewing’s sarcoma; chondrosarcoma; soft-tissue sarcoma; undifferentiated pleo-morphic sarcoma; liposarcoma; leiomyosarcoma; rhabdomyosarcoma; metastatic sarcoma; targeted molecular therapy; immunotherapy; orthopedic oncology

(This special issue belongs to the Section Oncology)

New Concepts in Minimally Invasive Spine Surgery

edited by

Yi Lu

and Michael Y. Wang

submission deadline 25 Oct 2026 | 3 articles | Viewed by 3184 | Submission Open

Keywords: minimally invasive spine surgery; image navigation; tubular retractor; endoscopic spine surgery; virtual and aug-mented reality; lateral spine surgery

(This special issue belongs to the Section Clinical Neurology)

Diabetic Retinopathy Screening: Current Advances and Future Options

edited by

Alauddin Bhuiyan

and

Roland Theodore Smith

submission deadline 25 Oct 2026 | 2 articles | Viewed by 3059 | Submission Open

Keywords: diabetic retinopathy; diabetic retinopathy screening; retinal imaging; age-related macular degeneration; artificial intelli-gence; image analysis; color fundus photography; optical coherence tomography imaging; telemedicine

(This special issue belongs to the Section Ophthalmology)

Controversies in Hidradenitis Suppurativa: Bridging Gaps in Science and Practice

edited by Hadar Lev-Tov and Tammy González

submission deadline 25 Oct 2026 | 4 articles | Viewed by 3014 | Submission Open

Keywords: hidradenitis suppurativa (HS); inflammatory skin disorder; controversies; treatment strategies; science and practice

(This special issue belongs to the Section Dermatology)

Recent Advances in Pulmonary Embolism and Thrombosis: 2nd Edition

edited by

Andrea Boccatonda

and Elena Campello

submission deadline 25 Oct 2026 | 2 articles | Viewed by 2730 | Submission Open

Keywords: pulmonary embolism; embolism and thrombosis; thrombus aspiration for pulmonary embolism; deep vein thrombosis; venous thromboembolism

(This special issue belongs to the Section Respiratory Medicine)

Clinical Epidemiology in Chronic Kidney Disease: 2nd Edition

edited by

Vincenzo Antonio Panuccio

and Claudia Torino

submission deadline 25 Oct 2026 | 3 articles | Viewed by 2347 | Submission Open

Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure

(This special issue belongs to the Section Nephrology & Urology)

Insight into Infectious Disease Epidemiology and Public Health

edited by

Francesco Rosiello

and Filomena Pietrantonio

submission deadline 25 Oct 2026 | 1 articles | Viewed by 2219 | Submission Open

Keywords: gender medicine; health management; public health; infectious disease, sindemics

(This special issue belongs to the Section Infectious Diseases)

Obstructive Sleep Apnea: Latest Advances and Prospects—2nd Edition

edited by

Carlos O’Connor-Reina

submission deadline 25 Oct 2026 | 1 articles | Viewed by 2195 | Submission Open

Keywords: obstructive sleep apnea; sleep medicine; myofunctional therapy; sleep surgery; neurostimulation; personalized treatment; biomarkers; adherence; home sleep testing

(This special issue belongs to the Section Otolaryngology)

Displaying special issue 401-450 on page 9 of 30.

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