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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bariatric Surgery: Challenges and Future Trends
edited by Hugo Santos-Sousa
submission deadline 20 Aug 2026 | 2 articles | Viewed by 4708 | Submission Open
Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures
(This special issue belongs to the Section General Surgery)
Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain submission deadline 20 Aug 2026 | 3 articles | Viewed by 4317 | Submission Open
Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain
(This special issue belongs to the Section Orthopedics)
Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights
edited by Scott G. Ravyts and Margot De Kooning
submission deadline 20 Aug 2026 | 3 articles | Viewed by 4165 | Submission Open
Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma
(This special issue belongs to the Section Mental Health)
Surgical Oncology: Clinical Application of Translational Medicine
edited by Domenico Parmeggiani
submission deadline 20 Aug 2026 | 4 articles | Viewed by 4030 | Submission Open
Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research
(This special issue belongs to the Section Oncology)
New Clinical Advances in Chronic Asthma—2nd Edition
edited by Vitaliano Nicola Quaranta
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3884 | Submission Open
Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids
(This special issue belongs to the Section Respiratory Medicine)
Myocarditis and Pericarditis: Clinical Advances and Current Challenges submission deadline 20 Aug 2026 | 1 articles | Viewed by 3804 | Submission Open
Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium
(This special issue belongs to the Section Cardiovascular Medicine)
Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations submission deadline 20 Aug 2026 | 3 articles | Viewed by 3696 | Submission Open
Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Applications of Cardiac Imaging: 2nd Edition
edited by Maria Concetta Pastore
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3603 | Submission Open
Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease
(This special issue belongs to the Section Cardiology)
Cancer Immunotherapy: Recent Advances and Clinical Challenges
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 3561 | Submission Open
Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms
(This special issue belongs to the Section Oncology)
Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis
edited by Luigi Carbone and Daniela Pugliese
submission deadline 20 Aug 2026 | 6 articles | Viewed by 3246 | Submission Open
Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies
(This special issue belongs to the Section Intensive Care)
Anesthesia and Intensive Care: Clinical Practices and Prospects
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 3167 | Submission Open
Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization
(This special issue belongs to the Section Intensive Care)
Breast Cancer: Symptoms, Types, Causes & Treatment
edited by Min-Jeong Cho and Sara Myers
submission deadline 20 Aug 2026 | 2 articles | Viewed by 3164 | Submission Open
Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies
(This special issue belongs to the Section Obstetrics & Gynecology)
Rehabilitation and Treatment of Post-COVID-19 Condition submission deadline 20 Aug 2026 | 2 articles | Viewed by 2875 | Submission Open
Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work
(This special issue belongs to the Section Clinical Rehabilitation)
Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition
edited by Tsutomu Yasukawa
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2828 | Submission Open
Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium
(This special issue belongs to the Section Ophthalmology)
Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction
edited by and Maria Maiello
submission deadline 20 Aug 2026 | 3 articles | Viewed by 2815 | Submission Open
Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health
(This special issue belongs to the Section Cardiovascular Medicine)
Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke submission deadline 20 Aug 2026 | 1 articles | Viewed by 2804 | Submission Open
Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment
(This special issue belongs to the Section Clinical Neurology)
Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2313 | Submission Open
Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)
(This special issue belongs to the Section Intensive Care)
Updates on Neuromuscular Diseases
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2280 | Submission Open
Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics
(This special issue belongs to the Section Clinical Neurology)
Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives
edited by Gheorghe Tomoaia and Daniel Oltean-Dan
submission deadline 20 Aug 2026 | 4 articles | Viewed by 2229 | Submission Open
Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery
(This special issue belongs to the Section Orthopedics)
Advances in the Management of Cervical Spine Trauma submission deadline 20 Aug 2026 | 3 articles | Viewed by 2164 | Submission Open
Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics submission deadline 20 Aug 2026 | 3 articles | Viewed by 2119 | Submission Open
Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care
(This special issue belongs to the Section Geriatric Medicine)
Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 2078 | Submission Open
Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment
(This special issue belongs to the Section Clinical Rehabilitation)
New Perspectives and Innovations in Critical Illness submission deadline 20 Aug 2026 | 3 articles | Viewed by 2074 | Submission Open
Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support
(This special issue belongs to the Section Intensive Care)
Endocrine Surgery: Current Treatment and Future Options
edited by Pietro Princi and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 2060 | Submission Open
Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation
(This special issue belongs to the Section General Surgery)
From Clinical Diagnosis to Effective Treatment of Cardiomyopathy submission deadline 20 Aug 2026 | 2 articles | Viewed by 1879 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Advances in Trauma and Orthopedic Surgery: 3rd Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 1761 | Submission Open
Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome
(This special issue belongs to the Section Orthopedics)
Advances in Maternal–Fetal Medicine
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1670 | Submission Open
Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Updates on Acromegaly
edited by , Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1659 | Submission Open
Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma
(This special issue belongs to the Section Endocrinology & Metabolism)
Recent Advances in Refractive Surgery and Intraocular Lens Implantation
edited by Antonio Leccisotti
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1577 | Submission Open
Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik
(This special issue belongs to the Section Ophthalmology)
New Insights into Orthodontic Treatment
edited by Federico Brugnami and Simonetta Meuli
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1570 | Submission Open
Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Optimizing Blood Management in Perioperative Cardiac Care: A Multidisciplinary Approach
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1526 | Submission Open
Keywords: perioperative cardiac care; patient blood management; cardiac surgery; blood transfusion; transfusion thresholds; bleeding management; hemostatic therapy; anticoagulation management; point‑of‑care coagulation testing
(This special issue belongs to the Section Cardiology)
New Developments and Challenges in Assisted Reproductive Technology
edited by and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1441 | Submission Open
Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging
edited by Katarzyna Nowomiejska
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1422 | Submission Open
Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications
(This special issue belongs to the Section Ophthalmology)
Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges
edited by Konstantinos Mourouzis
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1410 | Submission Open
Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification
(This special issue belongs to the Section Cardiovascular Medicine)
Diagnosis and Clinical Management in Hematologic Oncology
edited by Sunil Lakhwani and José María Raya-Sánchez
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1286 | Submission Open
Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management
(This special issue belongs to the Section Hematology)
Heart Failure and Transplant Cardiology: Latest Advances and Prospects
edited by Monika Budnik
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1237 | Submission Open
Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies
(This special issue belongs to the Section Cardiology)
Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1186 | Submission Open
Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Update on Prenatal Diagnosis and Maternal Fetal Medicine
edited by Gianluca Campobasso
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1177 | Submission Open
Keywords: fetal medicine; malformations; obstetric; prenatal diagnosis; artificial intelligence
(This special issue belongs to the Section Obstetrics & Gynecology)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Aug 2026 | 1 articles | Viewed by 1130 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Spine Neurosurgery: Latest Advances and Prospects
edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1062 | Submission Open
Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity
(This special issue belongs to the Section Clinical Neurology)
Future-Proof Care for Patients with Kidney Stones
edited by and Oliver Wiseman
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1041 | Submission Open
Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases
edited by Mariana Jinga and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 954 | Submission Open
Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders submission deadline 20 Aug 2026 | 1 articles | Viewed by 949 | Submission Open
Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation
(This special issue belongs to the Section Clinical Rehabilitation)
Contemporary Coronary Intervention: Innovation, Evidence, and Patient-Centred Outcomes
edited by Kevin Liou
submission deadline 20 Aug 2026 | 1 articles | Viewed by 901 | Submission Open
Keywords: percutaneous coronary interventions; coronary imaging; coronary physiology; precision medicine; CHIP PCI; stent-less technologies; clinical outcomes; pharmacotherapy in PCI; biomarkers; artificial intelligence in PCI; sustainability in PCI
(This special issue belongs to the Section Cardiology)
Current Trends and Progress in Eating Disorders and Obesity Management
edited by Davide Gravina, and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 795 | Submission Open
Keywords: eating disorders; anorexia nervosa; bulimia nervosa; binge-eating disorder; ARFID; obesity; neuromodulation; biomarkers; gut microbiome; pharmacological interventions; incretin receptor agonists; GLP-1; metreleptin; psychedelics
(This special issue belongs to the Section Mental Health)
Spine Surgery: Clinical Advances and Future Directions—2nd Edition
edited by Eun-Sang Kim and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 756 | Submission Open
Keywords: spine surgery; back pain; endoscopic spine surgery; cage implantation; neck pain
(This special issue belongs to the Section Clinical Neurology)
Physiotherapy: Multidisciplinary Interventions and Digital Health submission deadline 20 Aug 2026 | 1 articles | Viewed by 719 | Submission Open
Keywords: physiotherapy; rehabilitation; physical medicine; digital health; telemedicine; virtual reality; augmented reality; artifi-cial intelligence; robotic rehabilitation; wearable sensors; VR for educative goals; musculoskeletal, neurological, cognitive, pediatric, pulmonary, cardiac and gyneco-obstetric disorders; fibromyalgia syndrome; chronic pain; older adults
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Hearing Loss: Diagnosis, Treatment, and Management
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 718 | Submission Open
Keywords: hearing loss; deafness; bone conduction implants; middle ear implants; cochlear implants; myringoplasty; tympanoplasty; stapedotomy; ossicular chain reconstruction; imaging; audiological diagnostic
(This special issue belongs to the Section Otolaryngology)
Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition
edited by Dario Giorgio and Dario Pasquale Mucciolo
submission deadline 20 Aug 2026 | 1 articles | Viewed by 696 | Submission Open
Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging
(This special issue belongs to the Section Ophthalmology)
Anterior Segment Disorders
edited by Itay Lavy and
submission deadline 20 Aug 2026 | 1 articles | Viewed by 677 | Submission Open
Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life
(This special issue belongs to the Section Ophthalmology)
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