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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Translation of Technological Innovations in Diabetes Therapeutics

edited by

Nowreen Haq

submission deadline 20 Aug 2026 | 3 articles | Viewed by 5962 | Submission Open

Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

Management of Congenital Heart Disease (CHD)

edited by Sarah Nordmeyer and Marie Schafstedde

submission deadline 20 Aug 2026 | 6 articles | Viewed by 5579 | Submission Open

Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions

(This special issue belongs to the Section Cardiovascular Medicine)

Kidney Transplantation: State-of-the-Art Knowledge

edited by

Georgios Koimtzis

, Georgios Geropoulos and Kyriakos Psarras

submission deadline 20 Aug 2026 | 3 articles | Viewed by 5494 | Submission Open

Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection

(This special issue belongs to the Section Nephrology & Urology)

Current Concepts and Updates in Eye Diseases

edited by Wiktor Stopyra,

Joanna Konopińska

and Anna Machalinska

submission deadline 20 Aug 2026 | 4 articles | Viewed by 5234 | Submission Open

Keywords: corneal disease; glaucoma; cataract, uveitis; ocular oncology; retinal disorder; ocular treatment; eye surgery; ocular diagnostics

(This special issue belongs to the Section Ophthalmology)

Rising Star: Advanced Physical Therapy and Expansion

edited by

Hyolyun Roh

submission deadline 20 Aug 2026 | 3 articles | Viewed by 5073 | Submission Open

Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach

(This special issue belongs to the Section Clinical Rehabilitation)

Clinics and Management of Allergic and Inflammatory Skin Disorders

edited by

Andrzej Jaworek

and

Marta Szepietowska

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4936 | Submission Open

Keywords: allergic dermatoses; chronic inflammatory dermatoses; atopic dermatosis; contact dermatitis; chronic urticria; rosacea; psoriasis; hidradenitis suppurativa; diagnosis; comorbidities; management

(This special issue belongs to the Section Dermatology)

New Advances and Clinical Outcomes of Pediatric Endocrinology

edited by

Gerdi Tuli

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4866 | Submission Open

Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria

(This special issue belongs to the Section Clinical Pediatrics)

Musculoskeletal Pain: Clinical Management Updates

edited by

Carmen Ridao-Fernandez

submission deadline 20 Aug 2026 | 4 articles | Viewed by 4741 | Submission Open

Keywords: musculoskeletal pain; chronic pain; gait assessment; musculoskeletal disorders; patellofemoral pain

(This special issue belongs to the Section Clinical Rehabilitation)

Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)

edited by

Athena Gogali

and Georgios Hillas

submission deadline 20 Aug 2026 | 5 articles | Viewed by 4713 | Submission Open

Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging

(This special issue belongs to the Section Respiratory Medicine)

Bariatric Surgery: Challenges and Future Trends

edited by Hugo Santos-Sousa

submission deadline 20 Aug 2026 | 2 articles | Viewed by 4639 | Submission Open

Keywords: obesity; metabolic and bariatric surgery; sleeve gastrectomy; metabolic syndrome; novel surgical procedures; Nissen-sleeve fundoplication; Roux-en-Y gastric bypass distalization; single-anastomosis procedures

(This special issue belongs to the Section General Surgery)

Integrating Psychological Science into Chronic Pain Management: Emerging Approaches and Insights

edited by Scott G. Ravyts and Margot De Kooning

submission deadline 20 Aug 2026 | 3 articles | Viewed by 4039 | Submission Open

Keywords: chronic primary pain; nociplastic pain; coping strategies; depression; anxiety; trauma

(This special issue belongs to the Section Mental Health)

Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain

edited by

Maciej Rachwał

and

Joanna Baran

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3910 | Submission Open

Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain

(This special issue belongs to the Section Orthopedics)

Surgical Oncology: Clinical Application of Translational Medicine

edited by Domenico Parmeggiani

submission deadline 20 Aug 2026 | 4 articles | Viewed by 3815 | Submission Open

Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research

(This special issue belongs to the Section Oncology)

New Clinical Advances in Chronic Asthma—2nd Edition

edited by Vitaliano Nicola Quaranta

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3729 | Submission Open

Keywords: chronic asthma; breathlessness; coughing; inhaled corticosteroids (ICS); long-acting beta-agonists (LABAs); personalized treatment; chronic rhinosinusitis; nasal polyps; bronchiectasis; endotypes; oral corticosteroids

(This special issue belongs to the Section Respiratory Medicine)

Myocarditis and Pericarditis: Clinical Advances and Current Challenges

edited by

Ankit Agrawal

and

Tom Kai Ming Wang

submission deadline 20 Aug 2026 | 1 articles | Viewed by 3702 | Submission Open

Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Applications of Cardiac Imaging: 2nd Edition

edited by Maria Concetta Pastore

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3563 | Submission Open

Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Non-Pharmacological Therapies and Exercise Interventions in Clinical Populations

edited by

Jorge Sánchez-Infante

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3538 | Submission Open

Keywords: non-pharmacological interventions; physiotherapy approaches; physical activity; acute and chronic diseases; acute and chronic pain

(This special issue belongs to the Section Clinical Rehabilitation)

Cancer Immunotherapy: Recent Advances and Clinical Challenges

edited by

Antonello Veccia

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3494 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms

(This special issue belongs to the Section Oncology)

Breast Cancer: Symptoms, Types, Causes & Treatment

edited by Min-Jeong Cho and Sara Myers

submission deadline 20 Aug 2026 | 2 articles | Viewed by 3122 | Submission Open

Keywords: ductal carcinoma in situ (DCIS); breast cancer; breast cancer prevention; minimally invasive surgery; innovative imaging technologies

(This special issue belongs to the Section Obstetrics & Gynecology)

Anesthesia and Intensive Care: Clinical Practices and Prospects

edited by

Jungchan Park

submission deadline 20 Aug 2026 | 3 articles | Viewed by 3054 | Submission Open

Keywords: artificial intelligence; clinical decision support; perioperative risk stratification; perioperative patient safety; hemodynamic optimization

(This special issue belongs to the Section Intensive Care)

Rehabilitation and Treatment of Post-COVID-19 Condition

edited by

Indre Bileviciute-Ljungar

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2813 | Submission Open

Keywords: post-COVID-19 condition; myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS); comorbidities; interdisciplinary; multimodal; digital medicine; rehabilitation; treatment; health-related quality of life; disability; return to work

(This special issue belongs to the Section Clinical Rehabilitation)

Cardiovascular Prevention and Epidemiology: Innovations and Insights Bridging Research and Practice for Effective Risk Reduction

edited by

Pasquale Palmiero

and Maria Maiello

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2756 | Submission Open

Keywords: cardiovascular prevention; risk reduction; epidemiology; innovations; risk stratification; population health

(This special issue belongs to the Section Cardiovascular Medicine)

Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis

edited by Luigi Carbone and Daniela Pugliese

submission deadline 20 Aug 2026 | 6 articles | Viewed by 2752 | Submission Open

Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies

(This special issue belongs to the Section Intensive Care)

Enhancing and Rehabilitation of Gait and Mobility in Chronic Stroke

edited by

Maria-Arantzazu Ruescas-Nicolau

Marco Iosa

and

María Luz Sánchez-Sánchez

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2710 | Submission Open

Keywords: chronic stroke; gait rehabilitation; mobility; physical therapy; technology-assisted interventions; assessment

(This special issue belongs to the Section Clinical Neurology)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Aug 2026 | 4 articles | Viewed by 2708 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

Clinical Perspectives on Extracorporeal Membrane Oxygenation (ECMO)

edited by

Alexander Hermann

submission deadline 20 Aug 2026 | 4 articles | Viewed by 2216 | Submission Open

Keywords: extracorporeal membrane oxygenation (ECMO); extracorporeal life support (ECLS); extracorporeal cardiopulmonary resuscitation (eCPR); extracorporeal gas exchange; extracorporeal circulation; acute respiratory distress syndrome (ARDS); cardiogenic shock (CS)

(This special issue belongs to the Section Intensive Care)

Orthopaedic Trauma and Bone Healing: Recent Advances and Future Perspectives

edited by Gheorghe Tomoaia and Daniel Oltean-Dan

submission deadline 20 Aug 2026 | 4 articles | Viewed by 2133 | Submission Open

Keywords: orthopaedic trauma; fractures; minimally invasive fixation; bone healing; biomaterials; periprosthetic fractures; artificial intelligence; rehabilitation; complications; orthopaedic surgery

(This special issue belongs to the Section Orthopedics)

Updates on Neuromuscular Diseases

edited by

Menachem Sadeh

submission deadline 20 Aug 2026 | 4 articles | Viewed by 2086 | Submission Open

Keywords: neuromuscualr disorders; myopathies; neuropathies; neuromuscualr junction disorders; neurogenetics

(This special issue belongs to the Section Clinical Neurology)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2055 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Geriatric Acute Care: Multimorbidity, Frailty, and Integrated Diagnostics

edited by

Nicoletta Cerundolo

and

Carmine Siniscalchi

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2027 | Submission Open

Keywords: geriatric medicine; frailty; multidimensional assessment; lung ultrasound; point-of-care ultrasound; acute care of older adults; transitional care

(This special issue belongs to the Section Geriatric Medicine)

New Perspectives and Innovations in Critical Illness

edited by

Francesco Alessandri

and

Giovanni Giordano

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1996 | Submission Open

Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support

(This special issue belongs to the Section Intensive Care)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition

edited by

Rubén Cuesta-Barriuso

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1960 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Endocrine Surgery: Current Treatment and Future Options

edited by Pietro Princi and

Julia Staubitz-Vernazza

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1934 | Submission Open

Keywords: endocrine surgery; thyroid surgery; parathyroid surgery; adrenal gland surgery; neuroendocrine neoplasms; thyroid cancer; thyroid cancer treatment; surgical endocrinology; robotic endocrine surgery; laparoscopic adrenalectomy; ret-roperitoneoscopic adrenalectomy; parathyroidectomy; benign thyroid disease; thyroid ablation

(This special issue belongs to the Section General Surgery)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1792 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Advances in Trauma and Orthopedic Surgery: 3rd Edition

edited by

Christian von Rüden

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1692 | Submission Open

Keywords: trauma; fracture; fracture fixation; osteosynthesis; biomechanics; bone; approach; nonunion; joint replacement; outcome

(This special issue belongs to the Section Orthopedics)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1629 | Submission Open

Keywords: maternal–fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1624 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights into Orthodontic Treatment

edited by Federico Brugnami and Simonetta Meuli

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1550 | Submission Open

Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Refractive Surgery and Intraocular Lens Implantation

edited by Antonio Leccisotti

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1491 | Submission Open

Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik

(This special issue belongs to the Section Ophthalmology)

Coronary Artery Disease in the Era of Artificial Intelligence: Clinical Insights and Therapeutic Challenges

edited by Konstantinos Mourouzis

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1381 | Submission Open

Keywords: coronary artery disease; myocardial ischemia; coronary imaging; revascularization; cardiometabolic risk; biomarkers; artificial intelligence; endothelial dysfunction; inflammation; arterial stiffness; antiplatelet therapy; heart failure; intraoperative graft verification

(This special issue belongs to the Section Cardiovascular Medicine)

New Developments and Challenges in Assisted Reproductive Technology

edited by

Shuqin Wei

and

Justin Tan

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1350 | Submission Open

Keywords: assisted reproductive technology; in vitro fertilization; clinical protocols and innovations; embryo selection and evaluation; ethnicity and reproductive outcomes; live birth; cryopreservation and fertility preservation; maternal and offspring health outcomes; global perspectives in reproductive medicine

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Applications and Surgical Integration of Advanced Ophthalmic Imaging

edited by Katarzyna Nowomiejska

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1340 | Submission Open

Keywords: ophthalmic imaging; retina; intraoperative OCT; personalized treatment; clinical applications

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Clinical Management in Hematologic Oncology

edited by Sunil Lakhwani and José María Raya-Sánchez

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1199 | Submission Open

Keywords: hematologic malignancies; lymphoma; multiple myeloma; acute leukemia; myeloproliferative neoplasms; molecular diagnostics; targeted therapy; immunotherapy; prognostic biomarkers; clinical management

(This special issue belongs to the Section Hematology)

Heart Failure and Transplant Cardiology: Latest Advances and Prospects

edited by Monika Budnik

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1178 | Submission Open

Keywords: heart failure; heart transplantation; bridge to transplant; mechanical circulatory support; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Endometriosis: Advances in Diagnosis, Treatment, and Long-Term Outcomes

edited by

Francesco Martire

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1157 | Submission Open

Keywords: endometriosis; diagnosis and biomarkers; medical and surgical treatment; fertility and reproductive outcomes; pain management; quality of life; long-term follow-up

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Update on Prenatal Diagnosis and Maternal Fetal Medicine

edited by Gianluca Campobasso

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1090 | Submission Open

Keywords: fetal medicine; malformations; obstetric; prenatal diagnosis; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Spine Surgery and Postoperative Management

edited by Mitchell K. Ng

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1075 | Submission Open

Keywords: spine surgery; perioperative care; enhanced recovery after surgery (ERAS); multimodal analgesia; opioid-sparing strategies; neuromonitoring; perioperative optimization

(This special issue belongs to the Section Orthopedics)

Spine Neurosurgery: Latest Advances and Prospects

edited by Jun Jae Shin, Bong Ju Moon and Chang Kyu Lee

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1031 | Submission Open

Keywords: cervical spine; cervical myelopathy; ossification of the posterior longitudinal ligament (OPLL); endoscopic spine surgery; minimally invasive spine surgery; spinal deformity

(This special issue belongs to the Section Clinical Neurology)

Future-Proof Care for Patients with Kidney Stones

edited by

Stijn Roemeling

and Oliver Wiseman

submission deadline 20 Aug 2026 | 2 articles | Viewed by 993 | Submission Open

Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life

(This special issue belongs to the Section Nephrology & Urology)

Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders

edited by

Carla Sílvia Fernandes

and

Marta Campos Ferreira

submission deadline 20 Aug 2026 | 1 articles | Viewed by 923 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Displaying special issue 51-100 on page 2 of 30.

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