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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 20 Dec 2025 | Viewed by 137 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Lung Transplantation and Interventional Pulmonology
edited by Anupam Kumar and Frye Laura
submission deadline 20 Dec 2025 | Viewed by 137 | Submission Open
Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery
(This special issue belongs to the Section Respiratory Medicine)
Advances in Clinical Management of Temporomandibular Joint Diseases submission deadline 20 Dec 2025 | Viewed by 133 | Submission Open
Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advanced Technologies, Concepts, and Topics in Modern Neurosurgery
edited by and Ralf Stroop
submission deadline 20 Dec 2025 | Viewed by 130 | Submission Open
Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning
(This special issue belongs to the Section General Surgery)
Status, Application and Future Directions of Artificial Urinary Sphincters
edited by JiSung Shim
submission deadline 20 Dec 2025 | Viewed by 130 | Submission Open
Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO
(This special issue belongs to the Section Nephrology & Urology)
Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers submission deadline 20 Dec 2025 | Viewed by 97 | Submission Open
Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Innovations in Preeclampsia
edited by Jeffrey M. Denney and
submission deadline 22 Dec 2025 | 3 articles | Viewed by 12898 | Submission Open
Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects
edited by Maria Chiara Maccarone and
submission deadline 22 Dec 2025 | 2 articles | Viewed by 3380 | Submission Open
Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine
(This special issue belongs to the Section Orthopedics)
Scoliosis: Advances in Diagnosis and Management
edited by Michal Latalski
submission deadline 22 Dec 2025 | 3 articles | Viewed by 3357 | Submission Open
Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life
(This special issue belongs to the Section Orthopedics)
Oral Surgery: Recent Advances and Future Perspectives submission deadline 22 Dec 2025 | 1 articles | Viewed by 2748 | Submission Open
Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology
edited by Praveen Peddu
submission deadline 22 Dec 2025 | 1 articles | Viewed by 401 | Submission Open
Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition) submission deadline 22 Dec 2025 | Viewed by 181 | Submission Open
Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 24 Dec 2025 | Viewed by 293 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Sports Injury: Clinical Prevention and Treatment
edited by , Susana Pulgar and
submission deadline 25 Dec 2025 | 4 articles | Viewed by 19813 | Submission Open
Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV
(This special issue belongs to the Section Sports Medicine)
Skin Diseases: From Diagnosis to Treatment
edited by
submission deadline 25 Dec 2025 | 5 articles | Viewed by 15651 | Submission Open
Keywords: skin; melanoma; NMSC; CTCL; mesenchymal
(This special issue belongs to the Section Dermatology)
Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease
edited by
submission deadline 25 Dec 2025 | 6 articles | Viewed by 12013 | Submission Open
Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography submission deadline 25 Dec 2025 | 3 articles | Viewed by 10682 | Submission Open
Keywords: computed tomography (CT); spectral CT; dual-energy CT; dual-source spectral CT; dual-layer spectral CT; pho-ton-counting CT; photon-counting detector CT; spectral photon-counting CT; artificial intelligence; radiomics
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Headache: Updates on the Assessment, Diagnosis and Treatment submission deadline 25 Dec 2025 | 7 articles | Viewed by 9682 | Submission Open
Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise
(This special issue belongs to the Section Clinical Neurology)
Targeted Treatment of Kidney Stones
edited by Carmen Gonzalez-Enguita and
submission deadline 25 Dec 2025 | 4 articles | Viewed by 9608 | Submission Open
Keywords: shockwave lithotripsy; ureteroscopy; percutaneous nephrolithotomy; laser lithotripsy; minimally invasive techniques; stone recurrence prevention
(This special issue belongs to the Section Nephrology & Urology)
Thyroid Cancer: Clinical Diagnosis and Treatment
edited by Alfred A. Simental
submission deadline 25 Dec 2025 | 5 articles | Viewed by 9526 | Submission Open
Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery
(This special issue belongs to the Section Oncology)
Clinical Epidemiology in Chronic Kidney Disease
edited by and Claudia Torino
submission deadline 25 Dec 2025 | 7 articles | Viewed by 9483 | Submission Open
Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure
(This special issue belongs to the Section Nephrology & Urology)
New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias
edited by
submission deadline 25 Dec 2025 | 5 articles | Viewed by 8896 | Submission Open
Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block
(This special issue belongs to the Section Cardiology)
Anterior Cruciate Ligament (ACL): Innovations in Clinical Management
edited by Xaver Feichtinger, and Georg Brandl
submission deadline 25 Dec 2025 | 4 articles | Viewed by 7895 | Submission Open
Keywords: ACL; graft choice; ACL repair; ALL; tibial slope
(This special issue belongs to the Section Orthopedics)
Innovations in Maxillofacial Surgery
edited by , and Ignacio Navarro Cuéllar
submission deadline 25 Dec 2025 | 5 articles | Viewed by 7032 | Submission Open
Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Advances in Inflammatory and Infectious Skin Diseases (Second Edition)
edited by , Astrid Herzum and Paolo Romita
submission deadline 25 Dec 2025 | 4 articles | Viewed by 6350 | Submission Open
Keywords: atopic dermatitis; eczematous diseases; inflammatory skin diseases; chronic skin diseases; human herpesvirus; roseola syphilitica; psoriasis
(This special issue belongs to the Section Dermatology)
Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases
edited by Vincenzo Davide Palumbo
submission deadline 25 Dec 2025 | 3 articles | Viewed by 4316 | Submission Open
Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Recent Research Progress in Pediatric Orthopedic Surgery
edited by and Madeleine Willegger
submission deadline 25 Dec 2025 | 4 articles | Viewed by 4146 | Submission Open
Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand
(This special issue belongs to the Section Clinical Pediatrics)
Pulmonary Embolism: Clinical Advances and Future Opportunities
edited by James Horowitz
submission deadline 25 Dec 2025 | 3 articles | Viewed by 3319 | Submission Open
Keywords: pulmonary embolism; risk stratification; pulmonary embolism response teams; high risk PE; massive PE; intermediate risk PE; sub massive PE; catheter directed thrombolysis; catheter thrombectomy; catheter directed embolectomy; extra corporeal membrane oxygenation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Advances in Radiation Therapy for Cancers submission deadline 25 Dec 2025 | 2 articles | Viewed by 2892 | Submission Open
Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Insights in Skin Tumors: From Pathogenesis to Therapy
edited by Loredana Ungureanu and Simona C. Şenilǎ
submission deadline 25 Dec 2025 | 3 articles | Viewed by 2037 | Submission Open
Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology
(This special issue belongs to the Section Dermatology)
Clinical Aspects of Cardiac Arrhythmias and Arrhythmogenic Disorders
edited by and Jakub Baran
submission deadline 25 Dec 2025 | 3 articles | Viewed by 1736 | Submission Open
Keywords: non-invasive arrhythmia assessment; electrocardiography; invasive arrhythmia assessment; invasive electrophysiology; catheter ablation; implantable devices; rare diseases and arrhythmias; arrhythmia risk stratification; genetics aspects of arrhythmogenesis; channelopathy
(This special issue belongs to the Section Cardiology)
State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities
edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan
submission deadline 25 Dec 2025 | 2 articles | Viewed by 1561 | Submission Open
Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts
(This special issue belongs to the Section Cardiology)
Advances in Anterior Segment Surgery: Second Edition
edited by
submission deadline 25 Dec 2025 | 2 articles | Viewed by 1536 | Submission Open
Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry
(This special issue belongs to the Section Ophthalmology)
Innovations and Future Directions in Valvular Heart Disease: Imaging, Technology, and Translational Research
edited by , Muhammed Gerçek and Felix Rudolph
submission deadline 25 Dec 2025 | 2 articles | Viewed by 836 | Submission Open
Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis; minimally invasive surgery; concomitant valve disease
(This special issue belongs to the Section Cardiology)
Kidney Health Under Microscope
edited by
submission deadline 25 Dec 2025 | Viewed by 275 | Submission Open
Keywords: complications; IgA nephropathy; glomerulonephritis; atypical haemolytic uraemic syndrome; systemic vasculitis; lupus nephritis; mineral bone disease; anaemia; xenotransplantation; nephrolithiasis
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Imaging Techniques in Heart Failure Care
edited by David Snipelisky
submission deadline 25 Dec 2025 | Viewed by 268 | Submission Open
Keywords: heart failure; advanced imaging; cardiac imaging; echocardiography; cardiomyopathies
(This special issue belongs to the Section Cardiology)
Psychological Pain and Suicidal Behavior: Clinical Implications
edited by Adrián Alacreu-Crespo
submission deadline 25 Dec 2025 | Viewed by 263 | Submission Open
Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes
(This special issue belongs to the Section Mental Health)
Advances and Innovations in Hand Surgery
edited by , Jason Wink and Anthony Archual
submission deadline 25 Dec 2025 | Viewed by 221 | Submission Open
Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Myocardial Infarction: Clinical Management and Future Options
edited by
submission deadline 25 Dec 2025 | Viewed by 149 | Submission Open
Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device
(This special issue belongs to the Section Cardiology)
IgA Nephropathy: Clinical Updates and Prospects
edited by
submission deadline 25 Dec 2025 | Viewed by 129 | Submission Open
Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification
(This special issue belongs to the Section Nephrology & Urology)
Cardiac Rehabilitation: Clinical Challenges and New Insights
edited by Melissa Tracy
submission deadline 26 Dec 2025 | 3 articles | Viewed by 7905 | Submission Open
Keywords: cardiovascular disease; cardiac rehabilitation; atrial fibrillation
(This special issue belongs to the Section Cardiology)
Current Clinical Treatments and Challenges for Cardiovascular Diseases
edited by Georgios Bouras and
submission deadline 26 Dec 2025 | 4 articles | Viewed by 6754 | Submission Open
Keywords: heart failure; coronary artery disease; atrial fibrillation; cardiomyopathies; hypertension
(This special issue belongs to the Section Cardiovascular Medicine)
New Advances in Extracorporeal Life Support (ECLS)
edited by Robertas Stasys Samalavičius, and
submission deadline 26 Dec 2025 | 2 articles | Viewed by 4721 | Submission Open
Keywords: extracorporeal life support (ECLS); extracorporeal membrane oxygenation (ECMO); innovations in ECLS; respiratory failure; cardiogenic shock; eCPR
(This special issue belongs to the Section Emergency Medicine)
Current Clinical Advances and Challenges for Endourology submission deadline 26 Dec 2025 | 2 articles | Viewed by 1436 | Submission Open
Keywords: urolithiasis; upper tract urothelial carcinoma; benign prostatic hyperplasia; minimally invasive surgical therapies
(This special issue belongs to the Section Nephrology & Urology)
Multifactorial Causation and Therapies of Myopia: 2nd Edition submission deadline 26 Dec 2025 | 1 articles | Viewed by 867 | Submission Open
Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
Clinical Updates on Metabolic and Bariatric Surgery
edited by Maria-Jose Barahona
submission deadline 27 Dec 2025 | 1 articles | Viewed by 747 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; weight loss; obesity treatment; metabolic disorders
(This special issue belongs to the Section General Surgery)
Atrial Fibrillation Rhythm Management: Outcomes, Innovations, and Future Directions
edited by Roberto Scacciavillani and Gemma Pelargonio
submission deadline 28 Dec 2025 | 5 articles | Viewed by 4859 | Submission Open
Keywords: atrial fibrillation; catheter ablation; radiofrequency; cryoablation; pulsed field ablation; cardioneuroablation; left bundle branch area pacing
(This special issue belongs to the Section Cardiology)
Lung Transplantation: Current Strategies and Future Directions
edited by Omer Senbaklavaci and György Lang
submission deadline 28 Dec 2025 | 1 articles | Viewed by 1445 | Submission Open
Keywords: lung transplantation; graft optimization; immunosuppression; artificial lung; xenotransplantation; end-stage lung disease; donor lung preservation; chronic lung allograft dysfunction
(This special issue belongs to the Section Respiratory Medicine)
Imaging and Molecular Biomarkers: The New Approach to Degenerative Retinal Diseases submission deadline 28 Dec 2025 | 1 articles | Viewed by 330 | Submission Open
Keywords: ophthalmology; degenerative retinal diseases; imaging biomarkers; multimodal imaging; OCT; OCT angiography; molecular biomarkers; precision medicine; translational ophthalmic research
(This special issue belongs to the Section Ophthalmology)
Managements of Venous Thromboembolism submission deadline 29 Dec 2025 | 3 articles | Viewed by 1920 | Submission Open
Keywords: venous thromboembolism; deep vein thrombosis; pulmonary embolism; anticoagulation therapy; direct oral anticoagulants; risk stratification; bleeding risk; artificial intelligence; personalized medicine
(This special issue belongs to the Section Vascular Medicine)
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