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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Pacemaker Implantation: Past, Present, and Future Challenges

edited by Rahul N. Doshi and

Ankur A. Karnik

submission deadline 20 Jul 2026 | Viewed by 86 | Submission Open

Keywords: pacing; physiologic pacing; left bundle area pacing; leadless pacing; lead management

(This special issue belongs to the Section Cardiology)

Advances in Perioperative Anesthesia: Emerging Techniques and Clinical Practices

edited by Mitchell H. Tsai, Matthew Bergeron Allen and Roya Saffary

submission deadline 20 Jul 2026 | Viewed by 84 | Submission Open

Keywords: perioperative medicine; goal-concordant care; anesthesia co-management; postoperative outcomes; perioperative anesthesia

(This special issue belongs to the Section Anesthesiology)

Clinical Implications of Artificial Intelligence in Patient Care

edited by

Safa Elkefi

and

Luigi Lavorgna

submission deadline 20 Jul 2026 | Viewed by 81 | Submission Open

Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI

(This special issue belongs to the Section Clinical Research Methods)

Current Updates on Pediatric Neurological Disorders and Neurorehabilitation

edited by

Lidia Perenc

and

Justyna Podgórska-Bednarz

submission deadline 20 Jul 2026 | Viewed by 81 | Submission Open

Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy

(This special issue belongs to the Section Clinical Pediatrics)

Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options

edited by Antonio J. Amor and Tonet Serés-Noriega

submission deadline 20 Jul 2026 | Viewed by 78 | Submission Open

Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound

(This special issue belongs to the Section Cardiovascular Medicine)

Colorectal Surgery: Advances in Modern Clinical Management

edited by Algimantas A. Tamelis

submission deadline 20 Jul 2026 | Viewed by 78 | Submission Open

Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease

edited by

Beatrice Bacchi

and Aleksander Dokollari

submission deadline 20 Jul 2026 | Viewed by 74 | Submission Open

Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement

(This special issue belongs to the Section Cardiology)

New Perspective of Oral and Maxillo-Facial Surgery：2nd Edition

edited by

Valentino Vellone

Umberto Committeri

and Alessandra Lucchese

submission deadline 20 Jul 2026 | Viewed by 74 | Submission Open

Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches

edited by

Andrea Tufo

submission deadline 20 Jul 2026 | Viewed by 74 | Submission Open

Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Outcomes in Pediatric Neurosurgery

edited by

Petra Klinge

and Konstantina Svokos

submission deadline 20 Jul 2026 | Viewed by 74 | Submission Open

Keywords: functional outcomes; pediatric neurosurgery; quality of life; innovative technologies; global neurosurgery

(This special issue belongs to the Section Clinical Pediatrics)

Misconceptions and Myths in Dermatology: From Clinic to Clarity

edited by Simon M. Mueller and Oliver Brandt

submission deadline 20 Jul 2026 | Viewed by 74 | Submission Open

Keywords: misconceptions; misunderstanding; myths; errors; mistakes; skin; dermatology

(This special issue belongs to the Section Dermatology)

Cardiac Imaging: Emerging Techniques and Clinical Applications

edited by

Athanasios Frydas

and

Daniel A. Morris

submission deadline 20 Jul 2026 | Viewed by 73 | Submission Open

Keywords: 3D echocardiography; myocardial strain; artificial intelligence; automated quantification; cardiac MRI; cardiac CT; multimodality imaging; machine learning; image-based risk stratification; precision cardiology

(This special issue belongs to the Section Cardiology)

Current Advances and Future Perspectives in Cardiothoracic Surgery

edited by Tomislav Kopjar

submission deadline 20 Jul 2026 | Viewed by 71 | Submission Open

Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities

(This special issue belongs to the Section General Surgery)

New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery

edited by Enrique A. Testa and Daniel Poggio

submission deadline 20 Jul 2026 | Viewed by 71 | Submission Open

Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy

(This special issue belongs to the Section Orthopedics)

Colorectal Surgery: Current Concept and Emerging Trends

edited by

Valentin Calu

submission deadline 20 Jul 2026 | Viewed by 69 | Submission Open

Keywords: colorectal surgery; robotic surgery; neoadjuvant treatment; minimally invasive techniques; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside

edited by

Se Won Lee

and

Jihyo Hwang

submission deadline 20 Jul 2026 | Viewed by 68 | Submission Open

Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation

(This special issue belongs to the Section Orthopedics)

Sarcopenia: Prevention and Treatment Options

edited by Steven Phu

submission deadline 20 Jul 2026 | Viewed by 67 | Submission Open

Keywords: sarcopenia; skeletal muscle; ageing; falls; frailty; exercise; rehabilitation; nutrition

(This special issue belongs to the Section Geriatric Medicine)

Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients

edited by Driss Chaoui

submission deadline 20 Jul 2026 | Viewed by 65 | Submission Open

Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20

(This special issue belongs to the Section Hematology)

Applications of Artificial Intelligence and Digital Therapeutics in Clinical Medicine: 2nd Edition

edited by

Carlos Escobar

submission deadline 20 Jul 2026 | Viewed by 64 | Submission Open

Keywords: artificial intelligence; biometric sensors; deep learning; digital therapies; Internet of Things; machine learning; virtual reality; augmented reality

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Current Challenges and Innovation in Trauma and Acute Care Surgery

edited by Michel Teuben

submission deadline 20 Jul 2026 | Viewed by 63 | Submission Open

Keywords: traumatology; trauma surgery; acute care surgery; femur; injury

(This special issue belongs to the Section Emergency Medicine)

Clinical Diagnosis and Treatment in Oncology: Radiotherapy and Imaging Analysis

edited by

Giuseppe Ferrera

Pierpaolo Alongi

and

Francesco Cuccia

submission deadline 20 Jul 2026 | Viewed by 63 | Submission Open

Keywords: radiomics; metabolic imaging; radiotherapy; predictive factors; response models; PET-CT; artificial intelligence; biomarkers; machine-learning

(This special issue belongs to the Section Oncology)

Stereotactic and Functional Neurosurgery: Clinical Treatment and Future Direction

edited by Michael G. Hart

submission deadline 20 Jul 2026 | Viewed by 63 | Submission Open

Keywords: functional neurosurgery; stereotaxy; deep brain structures; brain computer interfaces; therapeutic delivery; symptom relief

(This special issue belongs to the Section Clinical Neurology)

Dental Care and Oral Health in Adolescents and Children

edited by

Karolina Gerreth

submission deadline 20 Jul 2026 | Viewed by 61 | Submission Open

Keywords: oral health; oral diseases; diagnosis; dental treatment; treatment methods; general health; pediatric dentistry; special care dentistry; immunodeficiency; pediatric dental surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Updates on Anesthesia and Perioperative Medicine

edited by Béla Fülesdi and

Sorin J. Brull

submission deadline 20 Jul 2026 | Viewed by 60 | Submission Open

Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety

(This special issue belongs to the Section Anesthesiology)

Clinical Outcomes in Lumbar Spinal Stenosis Treatment

edited by Rafał Staszkiewicz and

Beniamin Oskar Grabarek

submission deadline 20 Jul 2026 | Viewed by 59 | Submission Open

Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life

(This special issue belongs to the Section Orthopedics)

Clinical Updates on Application of Echocardiography

edited by Aydan Ewers

submission deadline 20 Jul 2026 | Viewed by 58 | Submission Open

Keywords: echocardiography; heart failure; cardiomyopathies; cardiac echocardiography; interventional cardiology; cardiac imaging; pulmonary hypertension

(This special issue belongs to the Section Cardiology)

Advances in the Management of Cough and Asthma

edited by Ebymar Arismendi

submission deadline 20 Jul 2026 | Viewed by 57 | Submission Open

Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma

(This special issue belongs to the Section Respiratory Medicine)

Targeting the Complement for the Treatment of Autoimmune and Neurodegenerative Diseases of the Central Nervous System

edited by Charalampos Skarlis,

Maria Anagnostouli

and

Evangelia Liouta

submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open

Keywords: complement; biologics; monoclonal antibodies; neurodegenerative diseases; CNS autoimmune diseases

(This special issue belongs to the Section Clinical Neurology)

Early Diagnosis and Treatment of Hepatitis B and C: Bridging Innovation and Implementation

edited by

Rawi Hazzan

and

Fadi Abu Baker

submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open

Keywords: hepatitis B virus (HBV); hepatitis C virus (HCV); hepatitis delta virus (HDV); early diagnosis; viral hepatitis elimination; functional cure; direct-acting antivirals (DAAs); antiviral therapy; treatment adherence; care cascade; screening programs; health policy

(This special issue belongs to the Section Infectious Diseases)

Current Therapeutic Approaches to Addictive Disorders

edited by Linda Haddad

submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open

Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support

(This special issue belongs to the Section Mental Health)

Diagnosis, Treatment and Prognosis of Head and Neck Cancer

edited by

Armando De Virgilio

and Elena Russo

submission deadline 20 Jul 2026 | Viewed by 54 | Submission Open

Keywords: head and neck neoplasms; surgical procedures; minimally invasive surgical procedures; radiotherapy; immunotherapy; biomarkers; treatment outcome; early diagnosis; prognosis; quality of life

(This special issue belongs to the Section Oncology)

Advances in Interventional Cardiology: From Access to Outcomes

edited by James Cotton and Benjamin Wrigley

submission deadline 20 Jul 2026 | Viewed by 54 | Submission Open

Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign

(This special issue belongs to the Section Cardiology)

Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention

edited by Marco Ciardetti and Alessio Mattesini

submission deadline 20 Jul 2026 | Viewed by 52 | Submission Open

Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification

(This special issue belongs to the Section Cardiology)

Perspectives in Bionic Reconstruction and Post-Amputation Management

edited by

Alexander Gardetto

and Jennifer Ernst

submission deadline 20 Jul 2026 | Viewed by 52 | Submission Open

Keywords: bionic reconstruction; advanced prosthetics; neurorehabilitation; sensory feedback; motor control

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Exploring Diagnostic and Therapeutic Advances in Neurodegenerative Disorders

edited by

Stefania Kalampokini

and Effrosyni Koutsouraki

submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open

Keywords: neurodegenerative disease; Parkinson’ s disease; Alzheimer’ s disease; Friedreich’ s ataxia; Huntington’ s disease; Lewy body dementia; dementia; immunosenescence; inflammaging

(This special issue belongs to the Section Clinical Neurology)

Current Advances in Non-Trauma Emergency Critical and Resuscitation Medicine

edited by

Sebastian Bergrath

submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open

Keywords: resuscitation; non-trauma critically ill; emergency department; resuscitation room management; neuro-critical emergency care; emergency department critical care

(This special issue belongs to the Section Emergency Medicine)

Clinical Challenges in Heart Failure Management: 2nd Edition

edited by Paolo Severino, Gaetano M. Ruocco and

Andrea D'Amato

submission deadline 20 Jul 2026 | Viewed by 48 | Submission Open

Keywords: acute heart failure; chronic heart failure; inotropic support; left ventricular assist device; cardiac contractility modulation; guanylate cyclase stimulators; quality of life; telemedicine; palliative care

(This special issue belongs to the Section Cardiology)

Clinical Advances in Pediatric Hepatobiliary Surgery

edited by Ioannis A. Ziogas

submission deadline 20 Jul 2026 | Viewed by 48 | Submission Open

Keywords: pediatric hepatobiliary surgery; pediatric transplantation; pediatric surgery; liver transplantation; biliary atresia; choledochal cyst; liver cancer

(This special issue belongs to the Section Clinical Pediatrics)

Orthodontics: Current Management and Future Options

edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė

submission deadline 20 Jul 2026 | Viewed by 46 | Submission Open

Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact

edited by

Daniela Opris-Belinski

submission deadline 20 Jul 2026 | Viewed by 46 | Submission Open

Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus; Sjö gren’ s disease; systemic sclerosis; idiopathic inflammatory myopathies; comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management

(This special issue belongs to the Section Immunology & Rheumatology)

Pediatric Surgery—Current Hurdles and Future Perspectives—2nd Edition

edited by

Osnat Zmora

submission deadline 20 Jul 2026 | Viewed by 46 | Submission Open

Keywords: congenital anomalies; esophageal atresia; anorectal malformations; pediatric trauma; necrotizing enterocolitis; pediatric oncology; biliary atresia

(This special issue belongs to the Section Clinical Pediatrics)

Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology

edited by

Riccardo Fenici

Donatella Brisinda

and

Peter Fenici

submission deadline 20 Jul 2026 | Viewed by 45 | Submission Open

Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence

(This special issue belongs to the Section Cardiology)

Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies

edited by

Iason Psilopatis

and

Christos Damaskos

submission deadline 20 Jul 2026 | Viewed by 44 | Submission Open

Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical

(This special issue belongs to the Section Obstetrics & Gynecology)

Reducing Modifiable Risk Factors to Prevent and Control Non-Communicable Diseases: 2nd Edition

edited by

Daniele Piovani

and

Gisella Figlioli

submission deadline 20 Jul 2026 | Viewed by 44 | Submission Open

Keywords: non-communicable disease; chronic disease; cardiovascular disease; cancer; chronic respiratory disease; diabetes; mental health; tobacco use; physical inactivity; unhealthy diet; alcohol use; disease prevention

(This special issue belongs to the Section Epidemiology & Public Health)

Updates on Reconstructive Urology

edited by

Fabio Campodonico

submission deadline 20 Jul 2026 | Viewed by 42 | Submission Open

Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder

(This special issue belongs to the Section Nephrology & Urology)

What We See Through Cardiac Imaging: Second Edition

edited by

Valeria Pergola

and

Francesca Mantovani

submission deadline 20 Jul 2026 | Viewed by 42 | Submission Open

Keywords: cardiomyopathies; multimodality imaging; echocardiography; cardiac-computed tomography; cardiac magnetic resonance; prognosis; arrhythmias; heart failure

(This special issue belongs to the Section Cardiology)

Therapeutic Advances in Hematological Malignancies: New Breakthroughs and Future Directions

edited by Seema Naik

submission deadline 20 Jul 2026 | Viewed by 41 | Submission Open

Keywords: leukemia; lymphoma; myeloma; cell therapy; targeted therapy

(This special issue belongs to the Section Hematology)

Clinical Advances in Application of Echocardiography

edited by

Ramdas G. Pai

submission deadline 20 Jul 2026 | Viewed by 40 | Submission Open

Keywords: echocardiography; Doppler; transesophageal echocardiography; stain imaging; valvular hemodynamics; non valvular hemodynamics; interventional echocardiography; 3-dimensional echocardiography; tissue Doppler imaging

(This special issue belongs to the Section Cardiology)

Novel Perspectives in Transcatheter Aortic Valve Implantation

edited by Nay Min Htun

submission deadline 20 Jul 2026 | Viewed by 40 | Submission Open

Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli

(This special issue belongs to the Section Cardiology)

Hypertrophic Cardiomyopathy: New Insights into Complications and Treatment

edited by Ilaria Dentamaro and Ciro Santoro

submission deadline 20 Jul 2026 | Viewed by 39 | Submission Open

Keywords: hypertrophic cardiomyopathy; complications; risk stratification; multimodality imaging; myosin inhibitors; precision medicine

(This special issue belongs to the Section Cardiology)

Displaying special issue 1351-1400 on page 28 of 31.

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