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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Advances and Future Perspectives in Interventional Cardiology

edited by

Jacob Zeitani

submission deadline 20 May 2026 | 2 articles | Viewed by 1342 | Submission Open

Keywords: trans-catheter valve repair and replacement; advanced coronary intervention; AI in decision making for trans-catheter aortic root and arch replacement; LAA occlusion; anti-arrhythmic therapy; right side of the heart

(This special issue belongs to the Section Cardiology)

Advances in Minimally Invasive Otolaryngology: Precision Techniques and Functional Outcomes

edited by Giovanni Colombo and

Matteo Di Bari

submission deadline 20 May 2026 | 2 articles | Viewed by 1232 | Submission Open

Keywords: advances in otolaryngology; endoscopic surgery; head and neck surgery; functional outcomes; quality of life

(This special issue belongs to the Section Otolaryngology)

Advances in Fertility Preservation

edited by Dunja Maria Baston-Büst

submission deadline 20 May 2026 | 1 articles | Viewed by 1182 | Submission Open

Keywords: fertility preservation; gonadotoxic treatment; chemotherapy; transgender; cryopreservation; ejaculate; testicular tissue; mature oocytes; immature oocytes; ovarian tissue; ovarian cortex

(This special issue belongs to the Section Obstetrics & Gynecology)

Challenges and Opportunities in Application of Laparoscopic, Robotic and Other Technological Advances in Gastrointestinal Surgery

edited by

Gianluca Cassese

and Fabrizio Panaro

submission deadline 20 May 2026 | 1 articles | Viewed by 1121 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; artificial intelligence; technological advances

(This special issue belongs to the Section General Surgery)

Surgical Management of Complex Spinal Pathologies: Challenges and Innovations

edited by

Spyridon Komaitis

submission deadline 20 May 2026 | 2 articles | Viewed by 1120 | Submission Open

Keywords: complex spinal surgery; adult spinal deformity; complex degenerative pathologies; revision spine surgery; spinal oncology; robotics; navigation; surgical outcomes

(This special issue belongs to the Section Orthopedics)

Recent Advances in Adverse Pregnancy and Neonatal Outcomes

edited by

Sae-kyung Choi

submission deadline 20 May 2026 | 1 articles | Viewed by 1112 | Submission Open

Keywords: maternal and fetal; adverse pregnancy; neonatal outcomes; newborns; cesarean section

(This special issue belongs to the Section Obstetrics & Gynecology)

Percutaneous Coronary Intervention: Latest Advances and Future Prospects

edited by

Alessandro Mandurino-Mirizzi

submission deadline 20 May 2026 | 1 articles | Viewed by 1008 | Submission Open

Keywords: percutaneous coronary intervention; coronary artery disease; intravascular imaging; intracoronary physiology; high-risk percutaneous coronary intervention; calcified coronary stenosis; chronic total occlusion; bifurcation disease

(This special issue belongs to the Section Cardiology)

New Updates in Pediatric Gastroenterology

edited by

Laura Trandafir

, Alina Stanescu-Popp and Oana Belei

submission deadline 20 May 2026 | Viewed by 995 | Submission Open

Keywords: pediatric gastroenterology and hepatology; inflammatory bowel disease; celiac disease; gastrointestinal diseases; esophageal diseases; endoscopy; gut microbiome; inflammatory bowel disease; functional GI disorders; nutritional management; precision medicine; gut– brain axis; transitional care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Diagnosis and Management of Obstructive Sleep Apnea Syndrome

edited by

Graziano Montaruli

Domenico Ciavarella

and

Michele Tepedino

submission deadline 20 May 2026 | 2 articles | Viewed by 978 | Submission Open

Keywords: obstructive sleep apnea (OSA); apnea-hypopnea index (AHI); oxygen desaturation index (ODI); mandibular advancement device (MAD); polysomnography; upper airway; continuous positive airway pressure (C-PAP)

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Clinical Rheumatology—2nd Edition

edited by

Jacopo Ciaffi

submission deadline 20 May 2026 | 1 articles | Viewed by 957 | Submission Open

Keywords: rheumatoid arthritis; spondylarthritis; interventional; osteoporosis; complex regional pain syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Physiotherapy in Clinical Practice: From Assessment to Rehabilitation

edited by

Inés Llamas Ramos

and

Rocío Llamas-Ramos

submission deadline 20 May 2026 | 1 articles | Viewed by 778 | Submission Open

Keywords: clinical assessment; rehabilitation; clinical practice; patient-centered care; physiotherapy innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Cutting Edge Research on Total Knee Arthroplasty

edited by

Nahum Rosenberg

submission deadline 20 May 2026 | 1 articles | Viewed by 621 | Submission Open

Keywords: total knee arthroplasty; robotic-assisted surgery; computer-navigated arthroplasty; implant design; kinematic alignment; enhanced recovery pathways; patient-reported outcomes; artificial intelligence in orthopedics; revision surgery

(This special issue belongs to the Section Orthopedics)

Cardiac Imaging in Cardiovascular Disorders

edited by Leif-Christopher Engel

submission deadline 20 May 2026 | Viewed by 580 | Submission Open

Keywords: coronary CT angiography; cardiac magnetic resonance imaging; molecular imaging; echocardiography; stress echocardiography; myocardial perfusion imaging

(This special issue belongs to the Section Cardiology)

Total Joint Arthroplasty: Innovations, Outcomes, and Challenges—Second Edition

edited by Hendrik Kohlhof

submission deadline 20 May 2026 | 1 articles | Viewed by 568 | Submission Open

Keywords: knee and hip replacements; joint replacement; biomechanics; revision arthroplasty; orthogeriatrics and perioperative management

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Neuroprognostication and Outcome Prediction After Cardiac Arrest

edited by

Erik Roman-Pognuz

submission deadline 20 May 2026 | 1 articles | Viewed by 482 | Submission Open

Keywords: neuroprognostication; cardiac arrest; neurological outcome prediction; biomarkers in brain injury; multimodal prog-nostic tools; EEG monitoring; somatosensory evoked potentials (SSEPs); magnetic resonance imaging (MRI) in prognos-tication; post-cardiac arrest care; hypoxic– ischemic brain injury; withdrawal of life-sustaining treatment (WLST); inten-sive care prognostic strategies

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates of Physical Therapy in Rehabilitation

edited by

Sofia Xergia

submission deadline 20 May 2026 | Viewed by 415 | Submission Open

Keywords: neurological rehabilitation; musculoskeletal rehabilitation; special populations; new technology in physical therapy

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Therapeutic and Management Strategies of Epilepsy—Social and Neuropsychological Aspects

edited by

Hideaki Kanemura

submission deadline 20 May 2026 | Viewed by 378 | Submission Open

Keywords: quality of life (QOL); cognition; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); social

(This special issue belongs to the Section Clinical Neurology)

New Therapies for Diabetic Foot Ulcer Management

edited by

Irene Sanz-Corbalan

and

Raúl J. Molines Barroso

submission deadline 20 May 2026 | Viewed by 350 | Submission Open

Keywords: diabetic foot disease; diabetic foot ulcers; wound healing; biomarkers; telemedicine; artificial intelligence; preven-tive strategies; advanced therapies; amputation prevention; diabetes complications; novel treatments

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Updates in Transfusion Medicine and Patient Blood Management

edited by

Carlos Jerico

and

José Antonio García-Erce

submission deadline 20 May 2026 | Viewed by 290 | Submission Open

Keywords: anaemia; bleeding; blood transfusion; patient blood management; transfusion medicine

(This special issue belongs to the Section Hematology)

Clinical Research in Vascular Access Devices

edited by

Antonio Gidaro

submission deadline 20 May 2026 | Viewed by 274 | Submission Open

Keywords: short peripheral catheters; long peripheral catheters; midline; peripherally inserted central catheters (PICCs); femoral-inserted central catheters (FICCs); centrally inserted central catheters (CICCs); totally implantable venous access devices (TIVAD); catheter-related bloodstream infection (CRBSI); catheter-associated bloodstream infection (CABSI); central line-associated bloodstream infection (CLABSI); catheter-related thrombosis (CRT); fibroblastic sleeve; infiltration; extravasation

(This special issue belongs to the Section Vascular Medicine)

Key Quality Indicators in Diagnosis and Treatment of Respiratory Diseases

edited by

Fotios Sampsonas

submission deadline 20 May 2026 | Viewed by 225 | Submission Open

Keywords: key quality indicators; respiratory disorders; audit; quality improvement; real-life data

(This special issue belongs to the Section Respiratory Medicine)

Interventional Cardiology: Clinical Advances and Future Perspectives

edited by Antonio Landi and

Andrea Milzi

submission deadline 20 May 2026 | Viewed by 224 | Submission Open

Keywords: percutaneous coronary intervention; myocardial infarction; interventional cardiology; cardiac catheterization; coronary artery disease; antithrombotic therapy; intravascular imaging; acute coronary syndrome; chronic coronary syndrome

(This special issue belongs to the Section Cardiology)

New Horizons in Aortic Valve Replacement

edited by Abdellaziz Dahou

submission deadline 20 May 2026 | Viewed by 206 | Submission Open

Keywords: aortic valve; aortic stenosis; TAVR; SAVR; valve durability; aortic valve replacement; transcatheter aortic valve replacement; surgical aortic valve replacement

(This special issue belongs to the Section Cardiology)

Ventricular Assist Devices: Clinical Advances in Practice and Future Perspectives

edited by Balakrishnan M. Mahesh

submission deadline 20 May 2026 | Viewed by 200 | Submission Open

Keywords: ventricular assist device; mechanical circulatory support; pulsatile pneumatic devices; microaxial intraventricular de-vices; magnetically levitated devices; cardiac transplantation; donor circulatory death; normothermic regional perfusion

(This special issue belongs to the Section Cardiology)

Novel Approaches in Cataract and Refractive Surgery

edited by Stephen T. Armenti

submission deadline 20 May 2026 | Viewed by 190 | Submission Open

Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery

(This special issue belongs to the Section Ophthalmology)

The Use of Circulating Extracellular Vesicles as a Tool in the Diagnosis, Monitoring and Treatment of Disease

edited by

Antonio Casado-Díaz

submission deadline 20 May 2026 | Viewed by 186 | Submission Open

Keywords: circulating extracellular vesicles; regenerative medicine; biomarker; diagnosis; exosomes; liquid biopsy

(This special issue belongs to the Section Clinical Laboratory Medicine)

Artificial Intelligence in Exercise, Rehabilitation and Health Promotion: A Clinical Perspective

edited by

Ki-Hyuk Lee

and

Koji Koyama

submission deadline 20 May 2026 | Viewed by 151 | Submission Open

Keywords: artificial intelligence; machine learning and deep learning; large language models (LLMs); explainable AI; exercise and physical activity; rehabilitation and sports medicine; clinical applications; chronic disease and preventive health; digital health and big data analytics

(This special issue belongs to the Section Sports Medicine)

Anesthesia in Head and Neck Surgery

edited by

Luigi V. La Via

and Antonino Maniaci

submission deadline 20 May 2026 | Viewed by 141 | Submission Open

Keywords: airway management; hemodynamic stability; perioperative monitoring; head and neck surgery; anesthesia

(This special issue belongs to the Section Anesthesiology)

Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology

edited by

Mohsen Ibrahim

submission deadline 20 May 2026 | Viewed by 134 | Submission Open

Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer

(This special issue belongs to the Section General Surgery)

Current Challenges in Oral and Maxillofacial Surgery

edited by

Federica Canfora

and Lucia Memé

submission deadline 20 May 2026 | Viewed by 132 | Submission Open

Keywords: oral and maxillofacial surgery; surgical management; virtual surgical planning; postoperative management; orthog-nathic surgery; reconstructive techniques; minimally invasive surgery; digital technologies; 3D printing

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Diagnosis and Treatment of Connective Tissue Diseases: A Clinician's Perspective: 2nd Edition

edited by

Agnieszka Żebrowska

Adam Reich

and Aleksandra Dańczak-Pazdrowska

submission deadline 20 May 2026 | Viewed by 128 | Submission Open

Keywords: connective tissue diseases; lupus erythematosus; scleroderma; dermatomyositis; MCTD; clinical picture; spectrum of clinical symptoms; treatment; complications; clinical follow-up

(This special issue belongs to the Section Immunology & Rheumatology)

Spine Surgery: Current Challenges and Opportunities

edited by Kambiz Sarahrudi

submission deadline 20 May 2026 | Viewed by 127 | Submission Open

Keywords: vertebral fracture; spine trauma; spinal cord injury; adjacent segment degeneration; infection; spondylodiscitis; verte-bral metastasis; osteoporotic fracture; fracture of sacrum; disk degeneration; degenerative spine surgery; minimally invasive spine surgery

(This special issue belongs to the Section Orthopedics)

Neurovascular Interventions: Evolving Techniques and Insights

edited by Delia Cannizzaro

submission deadline 20 May 2026 | Viewed by 125 | Submission Open

Keywords: endovascular treatment; intracranial aneurysms; AI in neurointerventional surgery; intracranial vascular malformation; new endovascular device

(This special issue belongs to the Section Clinical Neurology)

Clinical Progress in Oral and Maxillofacial Surgery

edited by Luis M. Junquera and Giuseppe Consorti

submission deadline 20 May 2026 | Viewed by 119 | Submission Open

Keywords: oral and maxillofacial surgery; craniofacial surgery; facial deformity; cleft lip and palate; TMJ surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Challenges in Pancreatitis Management

edited by

Yusuke Tando

submission deadline 20 May 2026 | Viewed by 119 | Submission Open

Keywords: acute pancreatitis; chronic pancreatitis; medical management; surgical management; nutritional support; pancreatic diabetes; clinical research; reviews

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Perioperative Pain Management: 3rd Edition

edited by

Felice Eugenio Agro

Giuseppe Pascarella

and

Fabio Costa

submission deadline 20 May 2026 | Viewed by 115 | Submission Open

Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound

(This special issue belongs to the Section Anesthesiology)

Clinical Trends and Prospects in Urology Surgery: 2nd Edition

edited by

Lazaros Tzelves

submission deadline 20 May 2026 | Viewed by 111 | Submission Open

Keywords: robotic surgery; laparoscopic surgery; endourology; minimally invasive surgery; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions

edited by Halina Cichoz-Lach and

Beata Kasztelan-Szczerbińska

submission deadline 20 May 2026 | Viewed by 111 | Submission Open

Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut– liver axis; organ-to-organ crosstalk

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Prevention, Treatment, and Prognosis of Cerebral Aneurysms

edited by

Murai Yasuo

submission deadline 20 May 2026 | Viewed by 110 | Submission Open

Keywords: cerebral aneurysm; subarachnoid hemorrhage; clipping; interventional surgery; mortarity; long-term; surgical com-plication; bypass

(This special issue belongs to the Section Clinical Neurology)

The Current Trend in the Management of Bruxism and Temporomandibular Disorders, 2nd Edition

edited by

Luís Eduardo Almeida

submission deadline 20 May 2026 | Viewed by 105 | Submission Open

Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Perspectives on Obesity and Bariatric Surgery: Outcomes and Complications

edited by Dilhana S. Badurdeen

submission deadline 20 May 2026 | Viewed by 104 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; Roux-en-Y Gastric Bypass (RYGB); sleeve gastrectomy; revisional bariatric surgery; complications; outcomes; weight loss maintenance; metabolic syndrome; type 2 diabetes remission; nutritional deficiencies; gastrointestinal adaptation; quality of life; long-term follow-up

(This special issue belongs to the Section General Surgery)

Advances in Demyelinating and Neuroinflammatory Disorders

edited by

Julían Benito-Léon

submission deadline 20 May 2026 | Viewed by 102 | Submission Open

Keywords: multiple sclerosis; neuromyelitis optica spectrum disorder; MOG antibody– associated disease; neuroinflammation; biomarkers; advanced imaging; disease-modifying therapies; clinical outcomes

(This special issue belongs to the Section Clinical Neurology)

Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research: Second Edition

edited by

Ivo Guber

submission deadline 20 May 2026 | Viewed by 101 | Submission Open

Keywords: presbyopia; cataract surgery; refractive surgery; femtosecond laser; intraocular lenses; corneal refractive procedures; phakic intraocular lenses; visual outcomes; patient-reported outcomes; surgical innovations

(This special issue belongs to the Section Ophthalmology)

Clinical Research Progress in Atrial Fibrillation

edited by

Roddy Hiram

submission deadline 20 May 2026 | Viewed by 101 | Submission Open

Keywords: atrial fibrillation; atrial arrhythmias; cardiac fibrosis; inflammation; electrical remodeling

(This special issue belongs to the Section Cardiology)

Strategies in Complex Hand Trauma: Bridging Orthopedics, Plastic Surgery and Rehabilitation

edited by Clarisa Simón-Pérez and

Pedro Hernandez-Cortes

submission deadline 20 May 2026 | Viewed by 100 | Submission Open

Keywords: complex hand trauma; orthopedics; plastic surgery; microsurgery; rehabilitation; functional reconstruction; multidis-ciplinary management

(This special issue belongs to the Section General Surgery)

The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications

edited by

Jonathan Guez

and

Rotem Saar

submission deadline 20 May 2026 | Viewed by 100 | Submission Open

Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications

(This special issue belongs to the Section Mental Health)

Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies

edited by Carla Contaldi

submission deadline 20 May 2026 | Viewed by 97 | Submission Open

Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification

(This special issue belongs to the Section Cardiology)

Acute Coronary Syndromes | Circulation Research

edited by

Leslie Marisol Lugo Gavidia

and

Roberto Pedrinelli

submission deadline 20 May 2026 | Viewed by 97 | Submission Open

Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors

(This special issue belongs to the Section Cardiology)

Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition

edited by

Elad Asher

submission deadline 20 May 2026 | Viewed by 92 | Submission Open

Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI

(This special issue belongs to the Section Cardiovascular Medicine)

Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition

edited by

Byung-Ki Cho

submission deadline 20 May 2026 | Viewed by 92 | Submission Open

Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis

(This special issue belongs to the Section Orthopedics)

Displaying special issue 951-1000 on page 20 of 31.

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