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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Approaches and Challenges in Oral Rehabilitation

edited by

Yoko Hasegawa

and Takayuki Kosaka

submission deadline 25 May 2026 | 1 articles | Viewed by 1055 | Submission Open

Keywords: oral rehabilitation; oral health; systemic health; dental innovation; neuroplasticity

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies

edited by

Kamil Nelke

Maciej Dobrzyński

and

Michał Gontarz

submission deadline 25 May 2026 | 1 articles | Viewed by 997 | Submission Open

Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Interstitial Lung Diseases: New Treatments Based on Treatable Traits

edited by Francesco Amati

submission deadline 25 May 2026 | 1 articles | Viewed by 505 | Submission Open

Keywords: interstitial lung diseases; progressive pulmonary fibrosis; phenotypes; endotypes; treatment; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Transcatheter Aortic Valve Implantation- Clinical Management and Future Challenges

edited by Mohamed Farag

submission deadline 25 May 2026 | 1 articles | Viewed by 488 | Submission Open

Keywords: transcatheter aortic valve implantation; TAVI; bicuspid aortic valve; small annulus; prosthesis– patient mismatch; coronary reaccess; valve-in-valve TAVI; leaflet modification

(This special issue belongs to the Section Cardiovascular Medicine)

Multiple Sclerosis and Demyelinating Disease: Clinical Treatment and Management

edited by Sotirios Giannopoulos

submission deadline 25 May 2026 | 1 articles | Viewed by 300 | Submission Open

Keywords: multiple sclerosis; demyelinating disease; comorbidities; disease modifying treatments; neuromuscular disorder; myasthenia gravis

(This special issue belongs to the Section Clinical Neurology)

Anemia: Clinical Updates in Diagnosis, Management, and Treatment

edited by

Joan-Lluis Vives-Corrons

submission deadline 25 May 2026 | Viewed by 266 | Submission Open

Keywords: anemia; diagnostic tools; hematology; artificial intelligence; targeted therapy; hereditary hemolytic anemia

(This special issue belongs to the Section Hematology)

High-Risk Neuroblastoma and Rhabdoid Tumors: New Clinical Insights and Challenges (Second Edition)

edited by

Rupert Handgretinger

and Johannes Hubertus Schulte

submission deadline 25 May 2026 | Viewed by 163 | Submission Open

Keywords: neuroblastoma; rhabdoid tumor; autologous stem cell transplantation; allogeneic stem cell transplantation immunotherapy; anti-GD2 antibody; targeted therapy; CAR T-cells

(This special issue belongs to the Section Oncology)

Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition

edited by David Saceda-Corralo

submission deadline 25 May 2026 | Viewed by 105 | Submission Open

Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia

(This special issue belongs to the Section Dermatology)

Surgical Innovation and Clinical Outcomes in Plastic and Reconstructive Surgery

edited by Pari Naz Mohanna and Ayush Kapila

submission deadline 25 May 2026 | Viewed by 76 | Submission Open

Keywords: plastic and reconstructive surgery; microsurgery; breast reconstruction; surgical innovation; novel flap techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Advances in the Clinical Management of Diabetic Retinopathy

edited by

Takeshi Iwase

submission deadline 25 May 2026 | Viewed by 73 | Submission Open

Keywords: retinal imaging; clinical outcomes; optical coherence tomography (OCT); vitrectomy; blood flow

(This special issue belongs to the Section Ophthalmology)

Current Perspectives on the Clinical Management of Respiratory Diseases

edited by

Pradeesh Sivapalan

and

Alexandr Ceasovschih

submission deadline 25 May 2026 | Viewed by 72 | Submission Open

Keywords: COPD; acute exacerbations; biomarkers; clinical trials; bronchiectasis; respiratory infections

(This special issue belongs to the Section Respiratory Medicine)

New Advances in Congenital Heart Disease

edited by

Efrén Martínez-Quintana

submission deadline 25 May 2026 | 1 articles | Viewed by 70 | Submission Open

Keywords: congenital heart disease; pediatric cardiology; adult congenital heart disease; cardiac surgery; interventional cardiology; long-term outcomes; cardiac imaging

(This special issue belongs to the Section Cardiology)

Clinical Advances and Challenges in Vascular and Endovascular Medicine: 2nd Edition

edited by

Luca Bertoglio

submission deadline 25 May 2026 | Viewed by 67 | Submission Open

Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies

(This special issue belongs to the Section Vascular Medicine)

Musculoskeletal Imaging and Intervention: 2nd Edition

edited by

Miguel Malo-Urriés

and

Jacobo Rodríguez-Sanz

submission deadline 25 May 2026 | Viewed by 66 | Submission Open

Keywords: ultrasound; invasive physiotherapy; minimally invasive surgical procedures; magnetic resonance; image analysis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Advances in Personalized Psychiatry

edited by

Rosaria Di Lorenzo

submission deadline 25 May 2026 | Viewed by 62 | Submission Open

Keywords: personalized psychiatry; biomarkers; predictive modeling; precision diagnosis; neuroimaging biomarkers; effective treatments

(This special issue belongs to the Section Mental Health)

Acute and Chronic Heart Failure: Clinical Updates and Perspectives—2nd Edition

edited by Luigi Cappannoli and Cristina Aurigemma

submission deadline 25 May 2026 | Viewed by 61 | Submission Open

Keywords: acute heart failure; chronic heart failure; devices; drug therapy; percutaneous ventricular assist devices; cardiogenic shock; arrhythmias; ischemic heart disease

(This special issue belongs to the Section Cardiovascular Medicine)

An Update to Trends and Strategies in Vascular and Endovascular Surgery

edited by Karin Pfister and Fiona Rohlffs

submission deadline 25 May 2026 | Viewed by 61 | Submission Open

Keywords: vascular surgery; endovascular surgery; carotid endarterectomy; peripheral vascular diseases; vascular imaging; aortic diseases; aortic aneurysm; arteriovenous malformation; pelvic venous disorder; endovenous procedures; pal-liative therapy concept

(This special issue belongs to the Section Vascular Medicine)

Clinical Diagnosis and Treatment of Demyelinating Diseases

edited by

Dimitrios Tzanetakos

and John S. Tzartos

submission deadline 25 May 2026 | Viewed by 60 | Submission Open

Keywords: demyelinating diseases of the CNS; demyelinating diseases of the PNS; multiple sclerosis; neuromyelitis optica spectrum disorder (NMOSD); myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD); clinical diagnosis; biomarkers; therapeutics

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in the Management of Abdominal and Thoracoabdominal Aortic Aneurysms

edited by

Daniela Mazzaccaro

submission deadline 25 May 2026 | Viewed by 58 | Submission Open

Keywords: abdominal aneurysm; thoraco-abdominal; computed-tomography angiography; branched endograft; branched endovascular aortic repair; fenestrated endograft; open surgery; 3-D printing

(This special issue belongs to the Section Vascular Medicine)

Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment

edited by

Cesare Guida

submission deadline 25 May 2026 | Viewed by 50 | Submission Open

Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer

(This special issue belongs to the Section Oncology)

Epilepsy and Cerebrovascular Disorders

edited by

Leonardo Roever

submission deadline 25 May 2026 | Viewed by 50 | Submission Open

Keywords: epilepsy; cerebrovascular disorders; stroke; post-stroke epilepsy; neuroinflammation; neuroimaging; electroenceph-alography; biomarkers; antiepileptic treatment; translational neuroscience

(This special issue belongs to the Section Clinical Neurology)

How Clinicians See the Use of AI in Psychiatry

edited by

Georgios Floros

submission deadline 25 May 2026 | Viewed by 44 | Submission Open

Keywords: artificial intelligence; psychiatry; patient care; psychotherapy

(This special issue belongs to the Section Mental Health)

Advances in Kidney Transplantation: 2nd Edition

edited by Pedro Ruiz-Esteban, Domingo Hernández and Veronica López

submission deadline 25 May 2026 | Viewed by 42 | Submission Open

Keywords: kidney transplant; acute rejection; biomarkers; artificial intelligence; post-transplant complications; graft survival

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Management of Urologic Diseases

edited by Francesco Pio Bizzarri and Calogero Casà

submission deadline 25 May 2026 | Viewed by 32 | Submission Open

Keywords: prostate cancer; bladder cancer; kidney cancer; uro-oncology; radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Cerebrovascular Disease: Symptoms, Diagnosis and Current Treatment—Second Edition

edited by Alba Scerrati and Giorgio Mantovani

submission deadline 28 May 2026 | Viewed by 63 | Submission Open

Keywords: ischemic stroke; cerebral aneurysms; cerebral vascular malformation; cerebral venous disease; cerebral venous thrombosis

(This special issue belongs to the Section Clinical Neurology)

Spine Surgery Innovations: Treatments and Technologies

edited by

Marco D. Burkhard

and Tomoyuki Asada

submission deadline 29 May 2026 | Viewed by 409 | Submission Open

Keywords: AI; robotics; navigation; muscle preservation; minimally invasive surgery; motion preservation; alignment targets; implant materials; bone growth factors; custom-made implants

(This special issue belongs to the Section Orthopedics)

Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care

edited by

Daniel Holzinger

and

Johannes Hofer

submission deadline 30 May 2026 | Viewed by 42 | Submission Open

Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology

(This special issue belongs to the Section Otolaryngology)

Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management

edited by

Isabel Rocha

and Sérgio Laranjo

submission deadline 31 May 2026 | 4 articles | Viewed by 4308 | Submission Open

Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Updates on Prosthodontics

edited by

Rubén Agustín Panadero

and Carla Fons-Badal

submission deadline 31 May 2026 | 2 articles | Viewed by 2548 | Submission Open

Keywords: dental prosthesis; dental implants; gingival treatment; gingival aesthetics; gingival treatment; dental aesthetics; dental ceramics; BOPT; surgical periodontal treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Male Infertility: Diagnosis, Management and ART Integration

edited by Despoina Mavrogianni and Sofoklis Stavros

submission deadline 31 May 2026 | Viewed by 1195 | Submission Open

Keywords: male infertility; assisted reproductive technologies (ART); intracytoplasmic sperm injection (ICSI); genetic testing; hormonal profiling; seminal biomarkers; sperm retrieval techniques; sperm selection; stem cell therapy; gene editing; reproductive endo-crinology; early pregnancy; implantation failure; recurrent miscarriage

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Personalized Management of Abdominal Surgery and Complications

edited by Ioannis Mantzoros and

Orestis Ioannidis

submission deadline 31 May 2026 | Viewed by 91 | Submission Open

Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery

(This special issue belongs to the Section General Surgery)

Early Prevention and Diagnosis of Atherosclerosis: From Clinical Progression to Patient Management

edited by

Anna Kabłak-Ziembicka

submission deadline 31 May 2026 | Viewed by 89 | Submission Open

Keywords: atherosclerosis; atherothrombotic molecular pathways; cardiovascular risk; monitoring of goals; pharmacological and non-pharmacological prevention; carotid and peripheral interventions

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances and Contemporary Applications of Echocardiography

edited by

Attila Nemes

submission deadline 31 May 2026 | Viewed by 69 | Submission Open

Keywords: echocardiography; speckle-tracking; three-dimensional; Doppler; cardiac; valve; vasculature

(This special issue belongs to the Section Cardiovascular Medicine)

Current Advances and Future Challenges in Heart Transplantation

edited by

Norihide Fukushima

submission deadline 31 May 2026 | Viewed by 58 | Submission Open

Keywords: heart transplantation; indication; surgical techniques; preoperative care; immunosuppressive regimens; mechanical circulatory support; donor assessment and management; cardiac donation after circulatory death; ex vivo machine perfusion; normothermic regional perfusion; cardiac xenotransplantation

(This special issue belongs to the Section Cardiology)

Advance in the Management of Cancer Pain

edited by Wojciech Leppert

submission deadline 31 May 2026 | Viewed by 32 | Submission Open

Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management

(This special issue belongs to the Section Epidemiology & Public Health)

Applications of Artificial Intelligence (AI) in Surgery

edited by

Syed Ali Haider

and

Antonio Jorge Forte

submission deadline 31 May 2026 | Viewed by 10 | Submission Open

Keywords: artificial intelligence; machine learning; surgical robotics; computer vision; predictive analytics; surgical decision support; perioperative care; surgical outcomes; digital surgery

(This special issue belongs to the Section General Surgery)

Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions

edited by Sophia Sakka

submission deadline 1 Jun 2026 | Viewed by 1084 | Submission Open

Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights on Pharmacologic and Non-Pharmacologic Therapy of Advanced Heart Failure

edited by

Michael Dandel

submission deadline 5 Jun 2026 | Viewed by 34 | Submission Open

Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections

(This special issue belongs to the Section Cardiology)

Sjogren’s Syndrome: Clinical Advances and Insights

edited by David A. Isenberg

submission deadline 7 Jun 2026 | Viewed by 43 | Submission Open

Keywords: xerostomia; xerophthalmia; non-Hodgkins lymphoma; autoimmune rheumatic diseases; Sjogren’ s syndrome

(This special issue belongs to the Section Immunology & Rheumatology)

Cardiovascular Health: Advances in Prevention, Treatment and Innovative Therapies

edited by

Ibadete Bytyçi

submission deadline 10 Jun 2026 | Viewed by 1065 | Submission Open

Keywords: atherosclerosis; dyslipidemia; cardiac risk factors; premature ASCVD; left atrium function; atrial fibrillation; coronary imaging

(This special issue belongs to the Section Cardiovascular Medicine)

Diabetes Mellitus and Emerging Health Challenges: A Multidisciplinary Perspective

edited by Katarzyna A. Majewska and

Agnieszka Zawada

submission deadline 10 Jun 2026 | Viewed by 129 | Submission Open

Keywords: diabetes mellitus; type 1 diabetes; type 2 diabetes; diabetic complications; prediabetes; diabetes treatment; autoimmune diabetes

(This special issue belongs to the Section Endocrinology & Metabolism)

Cardiac Arrest and Postcardiac Arrest Care: State of the Art and Future Directions

edited by

Jae-Hyug Woo

and Soheil Saadat

submission deadline 10 Jun 2026 | Viewed by 44 | Submission Open

Keywords: out-of-hospital cardiac arrest; cardiopulmonary resuscitation; postcardiac arrest syndrome; postcardiac arrest care; survival; neurologic outcomes

(This special issue belongs to the Section Emergency Medicine)

Cardiomyopathy: Diagnosis and Therapeutic Advances

edited by Ilaria Dentamaro and Annagrazia Cecere

submission deadline 10 Jun 2026 | Viewed by 40 | Submission Open

Keywords: cardiomiopathy; cardiac magnetic resonance (CMR); advanced echocardiography; heart failure; hypertrophic cardiomyopathy

(This special issue belongs to the Section Cardiology)

Clinical and Diagnostic Strategies for Glioma Treatment

edited by Aleksandrs Krigers and Egils Valeinis

submission deadline 10 Jun 2026 | Viewed by 40 | Submission Open

Keywords: glioma; glioblastoma; astrocytoma; oligodendroglioma; IDH; neuro-oncology; neurosurgery; radiotherapy; neuropathology; diagnostics; treatment

(This special issue belongs to the Section Clinical Neurology)

New Technologies for Personalized Medicine in Head and Neck Surgery

edited by

Carlos Navarro-Cuéllar

and

José Luis Cebríán-Carretero

submission deadline 10 Jun 2026 | Viewed by 38 | Submission Open

Keywords: personalized medicine; head and neck surgery; 3D printing; surgical navigation; artificial intelligence; computer-assisted surgery; regenerative medicine; precision oncology; craniofacial reconstruction; biomaterials; virtual surgical planning; genomics and proteomics; tissue engineering; functional rehabilitation

(This special issue belongs to the Section Otolaryngology)

Clinical Outcomes Improvement and Perioperative Management of Surgical Patients: 3rd Edition

edited by

Dimitrios E. Magouliotis

and

Dimitris Zacharoulis

submission deadline 10 Jun 2026 | Viewed by 34 | Submission Open

Keywords: clinical outcomes; surgery; quality; quality of life; quality improvement; postoperative; morbidity; postoperative care

(This special issue belongs to the Section General Surgery)

Systemic Sclerosis: State of the Art and Future Directions

edited by Antonino Mazzone and

Paola Maria Luigia Faggioli

submission deadline 12 Jun 2026 | Viewed by 27 | Submission Open

Keywords: systemic sclerosis; current knowledge; advanced knowledge; vasculopathy; interstitial lung disease; pulmonary arterial hypertension; perspectives; novelties

(This special issue belongs to the Section Dermatology)

Cardiac Arrest: Strategies, Innovations, and Improvements in Outcomes

edited by

Kei Hayashida

submission deadline 15 Jun 2026 | Viewed by 891 | Submission Open

Keywords: cardiac arrest; cardiopulmonary resuscitation; post-cardiac arrest syndrome; neurological outcomes

(This special issue belongs to the Section Cardiology)

Blood Cancers: Current Status and Future Challenges

edited by

Salvatore Perrone

and Massimo Breccia

submission deadline 15 Jun 2026 | Viewed by 461 | Submission Open

Keywords: acute myeloid leukemia; hematology; leukemia; venetoclax; blood disorders

(This special issue belongs to the Section Hematology)

Transjugular Intrahepatic Portosystemic Shunt: Challenges and Perspectives—2nd Edition

edited by

Lorenzo Ridola

, Stefania Gioia and

Silvia Nardelli

submission deadline 15 Jun 2026 | 1 articles | Viewed by 458 | Submission Open

Keywords: hepatic encephalopathy; spontaneous portal-systemic shunts; transjugular intrahepatic portosystemic shunt; cirrhosis; portal hypertension; sarcopenia; myosteatosis; gastrointestinal bleeding; ascites; non cirrhotic portal hypertension

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 1301-1350 on page 27 of 31.

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