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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current and Emerging Treatment Options in Intestinal and Stomach Neoplasms

edited by Alexandros E. Giakoustidis and

Ioannis Konstantinidis

submission deadline 20 Dec 2025 | Viewed by 155 | Submission Open

Keywords: colorectal cancer; colon cancer; gastric carcinoma; malignancy; gastroenterology; endoscopic techniques; therapeutic advancements; intestinal neoplasms

(This special issue belongs to the Section Oncology)

Clinical Research and Insights in Endometriosis

edited by

Nikolaos Machairiotis

submission deadline 20 Dec 2025 | Viewed by 151 | Submission Open

Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Clinical Management of Temporomandibular Joint Diseases

edited by

João Luiz Monteiro

submission deadline 20 Dec 2025 | Viewed by 149 | Submission Open

Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Dec 2025 | Viewed by 146 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Advanced Image-Enhanced Endoscopy and Colonoscopy

edited by

Giuseppinella Melita

Marcello F. Maida

and Simona Di Caro

submission deadline 20 Dec 2025 | Viewed by 145 | Submission Open

Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advanced Technologies, Concepts, and Topics in Modern Neurosurgery

edited by

Samer Zawy Alsofy

and Ralf Stroop

submission deadline 20 Dec 2025 | Viewed by 143 | Submission Open

Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning

(This special issue belongs to the Section General Surgery)

Advances in Lung Transplantation and Interventional Pulmonology

edited by Anupam Kumar and Frye Laura

submission deadline 20 Dec 2025 | Viewed by 141 | Submission Open

Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery

(This special issue belongs to the Section Respiratory Medicine)

Status, Application and Future Directions of Artificial Urinary Sphincters

edited by JiSung Shim

submission deadline 20 Dec 2025 | Viewed by 136 | Submission Open

Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO

(This special issue belongs to the Section Nephrology & Urology)

Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers

edited by

Akira Tsuburaya

and

Takashi Oshima

submission deadline 20 Dec 2025 | Viewed by 102 | Submission Open

Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Innovations in Preeclampsia

edited by Jeffrey M. Denney and

Liliya Yamaleyeva

submission deadline 22 Dec 2025 | 3 articles | Viewed by 14442 | Submission Open

Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity

(This special issue belongs to the Section Obstetrics & Gynecology)

Scoliosis: Advances in Diagnosis and Management

edited by Michal Latalski

submission deadline 22 Dec 2025 | 3 articles | Viewed by 4021 | Submission Open

Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life

(This special issue belongs to the Section Orthopedics)

Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects

edited by Maria Chiara Maccarone and

Stefano Masiero

submission deadline 22 Dec 2025 | 2 articles | Viewed by 3636 | Submission Open

Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine

(This special issue belongs to the Section Orthopedics)

Oral Surgery: Recent Advances and Future Perspectives

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | 1 articles | Viewed by 3332 | Submission Open

Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology

edited by Praveen Peddu

submission deadline 22 Dec 2025 | 1 articles | Viewed by 611 | Submission Open

Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition)

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | 1 articles | Viewed by 375 | Submission Open

Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances in Stereotactic Radiosurgery

edited by Shafak S. Aluwini

submission deadline 24 Dec 2025 | 1 articles | Viewed by 627 | Submission Open

Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery

(This special issue belongs to the Section Oncology)

Sports Injury: Clinical Prevention and Treatment

edited by

Carlos Lago-Fuentes

, Susana Pulgar and

Nuno Leite

submission deadline 25 Dec 2025 | 4 articles | Viewed by 22459 | Submission Open

Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV

(This special issue belongs to the Section Sports Medicine)

Skin Diseases: From Diagnosis to Treatment

edited by

Anna Colagrande

submission deadline 25 Dec 2025 | 6 articles | Viewed by 17463 | Submission Open

Keywords: skin; melanoma; NMSC; CTCL; mesenchymal

(This special issue belongs to the Section Dermatology)

Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease

edited by

Hidekazu Suzuki

submission deadline 25 Dec 2025 | 6 articles | Viewed by 13147 | Submission Open

Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Headache: Updates on the Assessment, Diagnosis and Treatment

edited by

Ernesto Anarte-Lazo

and

Carlos Bernal-Utrera

submission deadline 25 Dec 2025 | 7 articles | Viewed by 11388 | Submission Open

Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise

(This special issue belongs to the Section Clinical Neurology)

Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Dec 2025 | 3 articles | Viewed by 11312 | Submission Open

Keywords: computed tomography (CT); spectral CT; dual-energy CT; dual-source spectral CT; dual-layer spectral CT; pho-ton-counting CT; photon-counting detector CT; spectral photon-counting CT; artificial intelligence; radiomics

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Targeted Treatment of Kidney Stones

edited by Carmen Gonzalez-Enguita and

Alberto Budía-Alba

submission deadline 25 Dec 2025 | 4 articles | Viewed by 10352 | Submission Open

Keywords: shockwave lithotripsy; ureteroscopy; percutaneous nephrolithotomy; laser lithotripsy; minimally invasive techniques; stone recurrence prevention

(This special issue belongs to the Section Nephrology & Urology)

Thyroid Cancer: Clinical Diagnosis and Treatment

edited by Alfred A. Simental

submission deadline 25 Dec 2025 | 5 articles | Viewed by 10286 | Submission Open

Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery

(This special issue belongs to the Section Oncology)

Clinical Epidemiology in Chronic Kidney Disease

edited by

Vincenzo Antonio Panuccio

and Claudia Torino

submission deadline 25 Dec 2025 | 7 articles | Viewed by 10002 | Submission Open

Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure

(This special issue belongs to the Section Nephrology & Urology)

New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias

edited by

Simone Savastano

submission deadline 25 Dec 2025 | 5 articles | Viewed by 9517 | Submission Open

Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block

(This special issue belongs to the Section Cardiology)

Anterior Cruciate Ligament (ACL): Innovations in Clinical Management

edited by Xaver Feichtinger,

Thomas Hoffelner

and Georg Brandl

submission deadline 25 Dec 2025 | 4 articles | Viewed by 8555 | Submission Open

Keywords: ACL; graft choice; ACL repair; ALL; tibial slope

(This special issue belongs to the Section Orthopedics)

Innovations in Maxillofacial Surgery

edited by

Carlos Navarro-Cuéllar

José Luis Cebríán-Carretero

and Ignacio Navarro Cuéllar

submission deadline 25 Dec 2025 | 5 articles | Viewed by 7892 | Submission Open

Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Inflammatory and Infectious Skin Diseases (Second Edition)

edited by

Giulia Ciccarese

, Astrid Herzum and Paolo Romita

submission deadline 25 Dec 2025 | 4 articles | Viewed by 7308 | Submission Open

Keywords: atopic dermatitis; eczematous diseases; inflammatory skin diseases; chronic skin diseases; human herpesvirus; roseola syphilitica; psoriasis

(This special issue belongs to the Section Dermatology)

Recent Research Progress in Pediatric Orthopedic Surgery

edited by

Catharina Chiari

and Madeleine Willegger

submission deadline 25 Dec 2025 | 4 articles | Viewed by 4863 | Submission Open

Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand

(This special issue belongs to the Section Clinical Pediatrics)

Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases

edited by Vincenzo Davide Palumbo

submission deadline 25 Dec 2025 | 3 articles | Viewed by 4649 | Submission Open

Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Pulmonary Embolism: Clinical Advances and Future Opportunities

edited by James Horowitz

submission deadline 25 Dec 2025 | 4 articles | Viewed by 4568 | Submission Open

Keywords: pulmonary embolism; risk stratification; pulmonary embolism response teams; high risk PE; massive PE; intermediate risk PE; sub massive PE; catheter directed thrombolysis; catheter thrombectomy; catheter directed embolectomy; extra corporeal membrane oxygenation

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Radiation Therapy for Cancers

edited by

Rodica Maricela Anghel

Liviu Bîlteanu

and

Laura Florentina Rebegea

submission deadline 25 Dec 2025 | 2 articles | Viewed by 3387 | Submission Open

Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Insights in Skin Tumors: From Pathogenesis to Therapy

edited by Loredana Ungureanu and Simona C. Şenilǎ

submission deadline 25 Dec 2025 | 3 articles | Viewed by 2414 | Submission Open

Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology

(This special issue belongs to the Section Dermatology)

Clinical Aspects of Cardiac Arrhythmias and Arrhythmogenic Disorders

edited by

Piotr Bienias

and Jakub Baran

submission deadline 25 Dec 2025 | 3 articles | Viewed by 2010 | Submission Open

Keywords: non-invasive arrhythmia assessment; electrocardiography; invasive arrhythmia assessment; invasive electrophysiology; catheter ablation; implantable devices; rare diseases and arrhythmias; arrhythmia risk stratification; genetics aspects of arrhythmogenesis; channelopathy

(This special issue belongs to the Section Cardiology)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1767 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Advances in Anterior Segment Surgery: Second Edition

edited by

Mayank A. Nanavaty

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1754 | Submission Open

Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry

(This special issue belongs to the Section Ophthalmology)

Innovations and Future Directions in Valvular Heart Disease: Imaging, Technology, and Translational Research

edited by

Mohammad Kassar

, Muhammed Gerçek and Felix Rudolph

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1053 | Submission Open

Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis; minimally invasive surgery; concomitant valve disease

(This special issue belongs to the Section Cardiology)

Advances and Innovations in Hand Surgery

edited by

David L. Colen

, Jason Wink and Anthony Archual

submission deadline 25 Dec 2025 | 1 articles | Viewed by 501 | Submission Open

Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Kidney Health Under Microscope

edited by

Magdi Yaqoob

submission deadline 25 Dec 2025 | Viewed by 300 | Submission Open

Keywords: complications; IgA nephropathy; glomerulonephritis; atypical haemolytic uraemic syndrome; systemic vasculitis; lupus nephritis; mineral bone disease; anaemia; xenotransplantation; nephrolithiasis

(This special issue belongs to the Section Nephrology & Urology)

Psychological Pain and Suicidal Behavior: Clinical Implications

edited by Adrián Alacreu-Crespo

submission deadline 25 Dec 2025 | Viewed by 283 | Submission Open

Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes

(This special issue belongs to the Section Mental Health)

Cardiac Imaging Techniques in Heart Failure Care

edited by David Snipelisky

submission deadline 25 Dec 2025 | Viewed by 277 | Submission Open

Keywords: heart failure; advanced imaging; cardiac imaging; echocardiography; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Myocardial Infarction: Clinical Management and Future Options

edited by

Kenichi Sakakura

submission deadline 25 Dec 2025 | Viewed by 155 | Submission Open

Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device

(This special issue belongs to the Section Cardiology)

IgA Nephropathy: Clinical Updates and Prospects

edited by

Meritxell Ibernon

submission deadline 25 Dec 2025 | Viewed by 138 | Submission Open

Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification

(This special issue belongs to the Section Nephrology & Urology)

Cardiac Rehabilitation: Clinical Challenges and New Insights

edited by Melissa Tracy

submission deadline 26 Dec 2025 | 3 articles | Viewed by 9037 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; atrial fibrillation

(This special issue belongs to the Section Cardiology)

Current Clinical Treatments and Challenges for Cardiovascular Diseases

edited by Georgios Bouras and

Christos Kourek

submission deadline 26 Dec 2025 | 4 articles | Viewed by 7178 | Submission Open

Keywords: heart failure; coronary artery disease; atrial fibrillation; cardiomyopathies; hypertension

(This special issue belongs to the Section Cardiovascular Medicine)

New Advances in Extracorporeal Life Support (ECLS)

edited by Robertas Stasys Samalavičius,

Pranas Šerpytis

and

Holger Thiele

submission deadline 26 Dec 2025 | 2 articles | Viewed by 5059 | Submission Open

Keywords: extracorporeal life support (ECLS); extracorporeal membrane oxygenation (ECMO); innovations in ECLS; respiratory failure; cardiogenic shock; eCPR

(This special issue belongs to the Section Emergency Medicine)

Current Clinical Advances and Challenges for Endourology

edited by

Carlo Giulioni

and

Daniele Castellani

submission deadline 26 Dec 2025 | 2 articles | Viewed by 1686 | Submission Open

Keywords: urolithiasis; upper tract urothelial carcinoma; benign prostatic hyperplasia; minimally invasive surgical therapies

(This special issue belongs to the Section Nephrology & Urology)

Multifactorial Causation and Therapies of Myopia: 2nd Edition

edited by

César Villa Collar

Cristina Alvarez-Peregrina

and

David Piñero

submission deadline 26 Dec 2025 | 1 articles | Viewed by 973 | Submission Open

Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Metabolic and Bariatric Surgery

edited by Maria-Jose Barahona

submission deadline 27 Dec 2025 | 1 articles | Viewed by 1023 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; weight loss; obesity treatment; metabolic disorders

(This special issue belongs to the Section General Surgery)

Atrial Fibrillation Rhythm Management: Outcomes, Innovations, and Future Directions

edited by Roberto Scacciavillani and Gemma Pelargonio

submission deadline 28 Dec 2025 | 6 articles | Viewed by 5416 | Submission Open

Keywords: atrial fibrillation; catheter ablation; radiofrequency; cryoablation; pulsed field ablation; cardioneuroablation; left bundle branch area pacing

(This special issue belongs to the Section Cardiology)

Displaying special issue 201-250 on page 5 of 31.

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