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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Applications of Polymers in Organic Functional Materials
edited by
submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open
Keywords: functional polymers; polymer synthesis; stimuli-responsive polymers; self-healing polymers; nanostructured polymers; polymer composites; smart materials; polymeric catalysts; polymers in (bio)electronics; polymers for sustainable processes
(This special issue belongs to the Section Macromolecules)
Advances in Laboratory Animal Research for Precision Medicine in Cardiovascular Diseases
edited by Conrado Calvo
submission deadline 30 Sep 2025 | Viewed by 94 | Submission Open
Keywords: cardiovascular disease; experimental models and research; arrhythmias and cardiac electrophysiology; molecular science and imaging techniques; myocardial ischemia and heart failure; cardiac fibrillation and sudden cardiac death; circulation and blood vessels; diabetes and metabolic disorders; experimental datasets for precision medicine; data-driven in silico approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Future Challenges and Innovation in Gynecological Oncology submission deadline 30 Sep 2025 | Viewed by 79 | Submission Open
Keywords: gynecologic oncology; molecular biomarkers; personalized medicine; ovarian cancer; immunotherapy; tumor microenvironment; drug resistance; translational research
(This special issue belongs to the Section Molecular Oncology)
Natural Products for Neuroprotection and Neurodegeneration
edited by
submission deadline 30 Sep 2025 | Viewed by 77 | Submission Open
Keywords: natural products; bioactive compounds; neuroprotection; neurodegeneration
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Advances in Macroporous, Mesoporous, and Microporous Materials submission deadline 30 Sep 2025 | Viewed by 77 | Submission Open
Keywords: functional materials; nanomaterials; nanostructures; molecular systems; porous materials
(This special issue belongs to the Section Materials Science)
Advances in Microbial Genomics: Insights from Whole Genomes and Metagenomes submission deadline 30 Sep 2025 | Viewed by 76 | Submission Open
Keywords: microbial evolution; whole-genome sequencing; metagenomics; horizontal gene transfer; antimicrobial resistance; computational genomics
(This special issue belongs to the Section Molecular Genetics and Genomics)
Advancing Regenerative Medicine: Basic Research and Translation in Clinics
edited by
submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open
Keywords: regenerative medicine; stem cells; tissue engineering; exosomes; orthobiologics
(This special issue belongs to the Section Molecular Biology)
The Role of Protein Kinase in Health and Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open
Keywords: protein kinases; phosphorylation; cancer; neurological disorder; targeted therapies; metabolic diseases
(This special issue belongs to the Section Biochemistry)
Molecular Advances in Assisted Reproductive Technologies
edited by
submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open
Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology; morpho kinetics; in vitro gametogenesis; in vitro oocyte maturation; reproductive tissue cryopreservation; artificial intelligence (AI)
(This special issue belongs to the Section Molecular Biology)
Neurogenesis and Neurodegeneration: Insights into Regeneration and the Impact of Neurotrophins submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open
Keywords: neurogenesis; neurodegeneration and regeneration; neurotrophins; brain plasticity
(This special issue belongs to the Section Molecular Neurobiology)
New Insights into Lactoferrin: 2nd Edition submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open
Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability
(This special issue belongs to the Section Molecular Immunology)
Psychobiotics as Next-Generation Probiotics: A Holistic Approach to Mental Health and Gut–Brain Axis Modulation submission deadline 30 Sep 2025 | Viewed by 69 | Submission Open
Keywords: probiotics; gut microbiota; gut– brain axis; mental health
(This special issue belongs to the Section Molecular Biology)
Foundational Studies Using Model Systems for Molecular Insights into Metabolism, Aging, and Disease
edited by
submission deadline 30 Sep 2025 | Viewed by 68 | Submission Open
Keywords: Saccharomyces cerevisiae  and yeasts; Caenorhabditis elegans  and nematodes; Arabidopsis thaliana  and plants; Drosophila melanogaster; Mus musculus; established and emerging model systems  
(This special issue belongs to the Section Molecular Biology)
Molecular-Scale Design, Synthesis, and Applications of (Photo)Electrochemical Materials for Sustainable Energy and Environmental Solutions
edited by and
submission deadline 30 Sep 2025 | Viewed by 67 | Submission Open
Keywords: molecular-scale material engineering; photoelectrocatalysis/electrocatalysis; sustainable energy conversion; atomic-precision synthesis; environmental remediation technologies
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Genetic Engineering for Stress Tolerance in Crops
edited by
submission deadline 30 Sep 2025 | Viewed by 66 | Submission Open
Keywords: genetic engineering; stress tolerance; crop improvement; drought resistance; salt tolerance; heat stress; CRISPR; RNAi; genetic modification; synthetic biology; pest resistance; crop transformation; abiotic stress; environmental resilience
(This special issue belongs to the Section Molecular Plant Sciences)
Algae-Derived Bioactives: Key Molecular Interactions Govern High-Value Applications
edited by Evan Stephens and Kirsten Heimann
submission deadline 30 Sep 2025 | Viewed by 62 | Submission Open
Keywords: microalgae; macroalgae; cyanobacteria; bioactive compounds; health and nutrition; algal food products; market analysis
(This special issue belongs to the Section Molecular Microbiology)
Biological Effects of Radiation on Human Cells and Tissues submission deadline 30 Sep 2025 | Viewed by 62 | Submission Open
Keywords: radiation exposure; molecular pathways; inflammation; immune response; biochemical markers; electromagnetic hypersensitivity
(This special issue belongs to the Section Molecular Biology)
Recent Advances in New Biomarkers for Cancers
edited by
submission deadline 30 Sep 2025 | Viewed by 61 | Submission Open
Keywords: biomarkers; cancer research; liquid biopsy; epigenetic and genetic biomarkers; precision oncology; diagnosis; prognosis; prediction
(This special issue belongs to the Section Molecular Oncology)
Molecular Research in Airway Diseases submission deadline 30 Sep 2025 | Viewed by 61 | Submission Open
Keywords: airway diseases; inflammation; immunopharmacology; cellular models; biomarkers; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Horizons in Pain Therapeutics
edited by Alaa Abd-Elsayed
submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open
Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Medicinal Plant Resources—from Molecular Studies to Sustainable Use
edited by Ekaterina Kozuharova
submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open
Keywords: genetic improvement of medicinal plants; sustainable use; bioactive compounds
(This special issue belongs to the Section Molecular Plant Sciences)
Intercellular Adhesion and Inflammatory Response in Cancer
edited by Anna Pryczynicz
submission deadline 30 Sep 2025 | Viewed by 59 | Submission Open
Keywords: adhesion; cancer; cancer therapy; inflammation; microenvironment
(This special issue belongs to the Section Molecular Biology)
Metallopharmaceuticals: Current Trends and Future Perspectives in Cancer Immunoediting submission deadline 30 Sep 2025 | Viewed by 59 | Submission Open
Keywords: metal-based drugs; anticancer activity; mechanisms of action; tumor microenvironment; immune cell regulation; cancer immunity; metal– protein interactions; metal– nucleic acid interactions
(This special issue belongs to the Section Molecular Pharmacology)
Structure-Based Design of Drugs and Other Bioactive Molecules
edited by
submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open
Keywords: three-dimensional structure; molecular descriptor; molecular similarity; database searching; drug repositioning; target fishing; novel algorithm; data prediction
(This special issue belongs to the Section Molecular Informatics)
Molecular Insights and Treatments for Gynecological Cancers submission deadline 30 Sep 2025 | Viewed by 56 | Submission Open
Keywords: gynecological cancers; cancers; endometrial cancers; cervical cancer; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Genotypes and Experimental Advances in Xenotransplantation
edited by Konrad Fischer
submission deadline 30 Sep 2025 | Viewed by 56 | Submission Open
Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bone and Cartilage Injury and Repair: Molecular Aspects
edited by Silvia María Díaz-Prado
submission deadline 30 Sep 2025 | Viewed by 55 | Submission Open
Keywords: bone and cartilage repair; regenerative medicine; inflammation and immune response; stem cell therapy; extracellular matrix remodeling; biomaterials; drug delivery systems; therapeutic targets; biomarkers
(This special issue belongs to the Section Molecular Biology)
Emerging Biomaterials for Cartilage Regeneration
edited by
submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open
Keywords: osteoarthritis; glycosaminoglycans; biomaterials; cartilage regeneration; mesenchymal cells; chondrocytes
(This special issue belongs to the Section Biochemistry)
Molecular Mechanisms of Antiviral Agents and Antiviral Therapy submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open
Keywords: therapeutics; high-throughput screening; viral reverse genetics; luciferase; fluorescent; compound; repurpose; antiviral; diagnostics
(This special issue belongs to the Section Molecular Immunology)
The New Developments in Third-Generation Sequencing Methods in Human Rare Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open
Keywords: short-read sequencing; long-read sequencing; single-cell rna sequencing; spatial-transcriptomic sequencing; single-nucleotide sequencing; structural-variant sequencing; protein-omics sequencing
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hemolytic Anemia: From Molecular Mechanisms to Therapeutic Exploitation
edited by Joan-Lluis Vives-Corrons
submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open
Keywords: hemolytic anemias; red blood cells; sickle cell disease; targeted therapies; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Multifunctional Nano-Coatings for Biomedical Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open
Keywords: nanocoatings; nanomedicine; drug delivery; surface functionalization; diagnostics; therapeutics; prevention; stimuli-responsive materials; biomedical nanotechnology; targeted delivery systems; biocompatible coatings
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Research in Obesity and Obesity Related Disorders: 3rd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open
Keywords: biochemistry and molecular medicine; molecular and cellular mechanisms of disease pathogenesis; pathogenesis of metabolic disorders; the role of interaction between genetic and environmental factors in the pathogenesis of non-communicable diseases; atherosclerosis; obesity; obesity-related metabolic diseases and cancers
(This special issue belongs to the Section Molecular Biology)
Drug-Induced Toxicity and Its Role in Disease Progression and Therapeutic Outcomes submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open
Keywords: drug-induced toxicity; drug-drug interactions; drug delivery systems; toxicity; disease
(This special issue belongs to the Section Molecular Toxicology)
Study on the Microenvironment in Lymphoma submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open
Keywords: tumor microenvironment; lymphoma; hodgkin lymphoma; non-hodgkin lymphoma; burkitt lymphoma; follicular lymphoma; waldenströ m’ s macroglobulinemia; NK/T-cell lymphoma; diffuse large B-cell lymphoma; mantle cell lymphoma; marginal zone lymphoma; lymphoproliferative disorder; anaplastic large cell lymphoma; mediastinal B cell lymphoma; T-cell lymphomas
(This special issue belongs to the Section Molecular Oncology)
Molecular Application of Biomaterial in Skin Diseases
edited by
submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open
Keywords: chronic dermatoses; autologus material; PRP; stem cells; growth factors
(This special issue belongs to the Section Materials Science)
Emerging Viral Epidemics
edited by Nikolaos Siafakas
submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open
Keywords: emerging viruses; diagnostic virology; viral epidemiology; viral evolution; zoonotic infections; public health; surveillance
(This special issue belongs to the Section Molecular Microbiology)
Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification
edited by
submission deadline 30 Sep 2025 | Viewed by 51 | Submission Open
Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano– bio interactions; crop production; plant-based solutions; bio-corona
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research in Triple-Negative Breast Cancer: 2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 51 | Submission Open
Keywords: triple negative breast cancer; lymph node metastasis; PMP22; prediction model using deep learning
(This special issue belongs to the Section Molecular Oncology)
Advances in Biological Breeding and Molecular Biology of Tropical Crops
edited by Yongzan Wei
submission deadline 30 Sep 2025 | Viewed by 51 | Submission Open
Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics
(This special issue belongs to the Section Molecular Plant Sciences)
New Insights into Chemotherapeutic Agents in Cancer Treatment
edited by
submission deadline 30 Sep 2025 | Viewed by 51 | Submission Open
Keywords: chemotherapy; molecular mechanisms; signal transduction; apoptosis; drug resistance; biomarkers; DNA damage; targeted therapy; cancer pathways; nanoparticles; nanomedicine; epigenetics
(This special issue belongs to the Section Molecular Pharmacology)
Bioactive Peptides: Function, Metabolism and Synthesis submission deadline 30 Sep 2025 | Viewed by 50 | Submission Open
Keywords: bioactive peptides; antimicrobial peptides; antitumoral peptides; neurodegenerative diseases; metabolic diseases; chemical synthesis; cellular proteolysis; mass spectrometry; peptidomics; intracellular peptides; micropeptides
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Recent Molecular Research in Colitis submission deadline 30 Sep 2025 | Viewed by 50 | Submission Open
Keywords: colitis; inflammatory bowel disease (IBD); gut-brain axis; intestinal barrier; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications
edited by
submission deadline 30 Sep 2025 | Viewed by 50 | Submission Open
Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Research and Immune Landscape of Breast Cancer
edited by
submission deadline 30 Sep 2025 | Viewed by 50 | Submission Open
Keywords: breast cancer; immune landscape; single-cell analysis; omics; therapy resistance; metastasis
(This special issue belongs to the Section Molecular Immunology)
Molecular and Clinical Advances in Ophthalmic Inflammation, Infection, and Degeneration
edited by Hyun Jin Shin
submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open
Keywords: ophthalmic inflammation; ocular infection; ocular degeneration; molecular mechanisms; translational research
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Influence of Genetics on Lymphatic System Diseases submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open
Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function
(This special issue belongs to the Section Molecular Genetics and Genomics)
Statin Induced Neurotoxicity submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open
Keywords: mitochondrial dysfunction; oxidative stress; coenzyme Q10; simvastatin; neurotoxicity; blood brain barrier
(This special issue belongs to the Section Molecular Neurobiology)
Inflammatory Bowel Disease: Molecular Insights—2nd Edition
edited by
submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open
Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’ s disease; ulcerative colitis; multiomics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism and Breeding of Abiotic and Biotic Stress Tolerance in Crops submission deadline 30 Sep 2025 | Viewed by 46 | Submission Open
Keywords: crop production; abiotic stress; biotic stress; genetic mechanism; molecular markers; crop variety improvement
(This special issue belongs to the Section Molecular Plant Sciences)
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