Foundational Studies Using Model Systems for Molecular Insights into Metabolism, Aging, and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 58
Special Issue Editor
Interests: gene expression; genetics; genomics; aging; biochemistry; molecular biology; fungi
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Our current understanding of the processes that underlie metabolism, aging, and disease is largely possible because of foundational studies performed using many diverse model organisms. Indeed, model systems are essential for the dissection of complex biological processes. Oftentimes, work within model systems provides the foundation for insights that can ultimately lead to improvements in our ability to understand and treat diseases. This is ultimately due to many contributing factors, including the conservation of molecular processes throughout eukaryotes—including humans—combined with the vast number of available tools. At the present time there are more model systems and resources available to researchers than ever before, including an ever-expanding repertoire of sequenced genomes, organismal databases, and mutant libraries—all of which can be used to probe complex biological processes at the molecular level.
The aim of this Special Issue is to welcome foundational studies that provide molecular insights using a broad variety of model systems, including:
- Saccharomyces cerevisiae and other yeasts (including pathogens and fission yeasts);
- Caenorhabditis elegans and other nematodes;
- Arabidopsis thaliana and plants;
- Drosophila melanogaster and other flies and insects;
- Mus musculus and other rodents.
We encourage submissions of research articles and short communications that present novel research and findings that provide molecular insight into processes that further our understanding of metabolism, aging, and disease. Both review and articles that have a focus on these topics are also welcome, and their submission is likewise encouraged.
Dr. James T. Arnone
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- Saccharomyces cerevisiae and yeasts
- Caenorhabditis elegans and nematodes
- Arabidopsis thaliana and plants
- Drosophila melanogaster
- Mus musculus
- established and emerging model systems
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