The Role of Protein Kinase in Health and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 96
Special Issue Editor
Special Issue Information
Dear Colleagues,
Protein kinases are enzymes that modify other proteins by adding phosphate groups, playing a vital role in cellular processes such as growth, differentiation, and apoptosis. They are classified into two main types: serine/threonine kinases, which target serine and threonine residues, and tyrosine kinases, which phosphorylate tyrosine residues. Dysregulated kinase activity is linked to various diseases, including cancer, neurological disorders (such as Alzheimer's and Parkinson's), and metabolic diseases like diabetes and obesity. Abnormal kinase function can lead to uncontrolled cell proliferation and disrupt essential signaling pathways. Understanding the roles of protein kinases in disease is crucial for developing targeted therapies aimed at restoring cellular balance and improving patient outcomes. This Special Issue calls for original research and reviews on protein kinases in disease and potential therapeutic interventions.
Dr. Manuela Loi
Guest Editor
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Keywords
- protein kinases
- phosphorylation
- cancer
- neurological disorder
- targeted therapies
- metabolic diseases
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