Molecular and Cellular Research on Cardiac Repair and Regeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 August 2025 | Viewed by 69
Special Issue Editors
Interests: cardiac stromal cells biology; non-coding RNA; cardiac fibrosis; cardiac stromal cells mediated signalling
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases remain a leading cause of morbidity and mortality worldwide, highlighting the urgent need for innovative therapeutic strategies. This Special Issue aims to explore the latest molecular and cellular research on cardiac repair and regeneration, with a focus on the mechanisms that drive these processes and their potential therapeutic applications.
Key topics include cellular and molecular pathways involved in heart regeneration, such as cardiomyocyte differentiation and proliferation, stromal cell activation and function in cardiac tissue repair, extracellular matrix homeostasis and remodeling, and angiogenesis. We welcome studies on novel mechanisms, therapeutic targets and strategies, including gene and RNA-based therapies, epigenetic regulation, and bioengineering approaches to model cardiovascular injury and study repair. Additionally, research on signaling pathways that modulate cardiac repair as well as mediating intercellular crosstalk among the various cardiac resident cell types is of particular interest. The role of inflammation, immune response, and fibrosis resolution in heart tissue regeneration will also be explored.
By gathering cutting-edge original articles and reviews, this Special Issue seeks to provide new insights into the design of innovative strategies for improving heart repair and function, bridging the gap between basic science and clinical applications.
Dr. Francesca Pagano
Dr. Vittorio Picchio
Guest Editors
Manuscript Submission Information
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Keywords
- cardiac repair
- cardiomyocyte differentiation
- cardiac fibroblast activation
- cardiac fibrosis
- cardiac tissue microenvironment
- cardiac remodeling
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