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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondria: Central Players in Cancer

edited by Annamaria Piscazzi and

Domenica Mangieri

submission deadline 30 Jun 2025 | Viewed by 843 | Submission Open

Keywords: mitochondria; cancer; tumorigenesis; oxidative phosphorylation; glycolysis; Warburg effect; reactive oxygen species (ROS); apoptosis; mitochondrial dysfunction; metabolic reprogram-ming; cancer therapy

(This special issue belongs to the Section Molecular Biology)

Genetics and Breeding for Sugar Crops

edited by Muqing Zhang

submission deadline 30 Jun 2025 | 1 articles | Viewed by 815 | Submission Open

Keywords: sugarcane; molecular genetics and breeding; plant pathology; stress biology; GWAS; QTL; precision breeding; molecular marker; gene editing; transgene

(This special issue belongs to the Section Molecular Plant Sciences)

Metabolomics in Coronary Artery Disease: From Pathogenesis to Personalized Medicine

edited by

Tomasz Urbanowicz

submission deadline 30 Jun 2025 | 1 articles | Viewed by 772 | Submission Open

Keywords: coronary artery disease (CAD); atherosclerosis; epicardial disease; CAD pathogenesis; personalized approach; drug response; metabolomic

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Plant Metabolism and Natural Product Biosynthesis

edited by

Andrej Frolov

submission deadline 30 Jun 2025 | 1 articles | Viewed by 758 | Submission Open

Keywords: plant metabolism; natural product; biosynthesis; metabolomics; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Therapeutics for Diabetes and Related Complications, 2nd Edition

edited by

Kota V. Ramana

submission deadline 30 Jun 2025 | 1 articles | Viewed by 711 | Submission Open

Keywords: diabetes; diabetes complications; molecular therapeutics; drug development; hyperglycemia; insulin resistance; cell signaling and oxidative stress

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Batteries and Electrochemical Sensors: Design, Development and Application

edited by Zhengkun Xie

submission deadline 30 Jun 2025 | Viewed by 691 | Submission Open

Keywords: novel electrodes and electrolytes; high-energy density batteries; characterization techniques; advanced electrochemical sensor; key analytes

(This special issue belongs to the Section Materials Science)

Aquatic Biotechnology and Its Application in Genetic Breeding—2nd Edition

edited by

Hui Qiao

submission deadline 30 Jun 2025 | 2 articles | Viewed by 685 | Submission Open

Keywords: aquaculture; biotechnology; germplasm improvement; genetic breeding; gene function; genomics; gene editing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Pathogenesis and Therapy of Oral Carcinogenesis, 3rd Edition

edited by

Marko Tarle

and

Ivica Lukšić

submission deadline 30 Jun 2025 | Viewed by 632 | Submission Open

Keywords: oral cancer; oral premalignant disorders; tumor microenvironment; molecular biomarkers; targeted therapy; oral tumorigenesis

(This special issue belongs to the Section Molecular Oncology)

Eye Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by

Tomasz Chorągiewicz

and

Joanna Dolar-Szczasny

submission deadline 30 Jun 2025 | 1 articles | Viewed by 631 | Submission Open

Keywords: eye diseases; genetic; biochemical; proteomic; cellular and physiological level; innovative therapeutic approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oxidative Stress and Mitochondria in Human Diseases

edited by

Alejandra Espinosa

submission deadline 30 Jun 2025 | Viewed by 584 | Submission Open

Keywords: mitochondrial dynamics; ROS; antioxidants; mitophagy; oxidative damage; lipid peroxidation; neurodegenerative diseases; cancer; obesity

(This special issue belongs to the Section Biochemistry)

Osteoarthritis: From Pathophysiology to Novel Therapy

edited by

Paloma Guillem-Llobat

submission deadline 30 Jun 2025 | 1 articles | Viewed by 575 | Submission Open

Keywords: osteoarthritis; therapeutic targets; molecular mechanisms; biomarkers; bone degenerative disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oxidative Stress in Human Diseases

edited by

Galina Nikolova

submission deadline 30 Jun 2025 | 1 articles | Viewed by 568 | Submission Open

Keywords: inflammation; oxidative stress; free radicals; proteins; lipids; DNA damage; biomarkers

(This special issue belongs to the Section Biochemistry)

Brain-Body Interactions in Mental Disorders: Molecular Mechanisms and Therapeutics

edited by Yan-Xue Xue

submission deadline 30 Jun 2025 | 1 articles | Viewed by 561 | Submission Open

Keywords: mental disorders; brain– body interactions; neural mechanisms; therapeutics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Cancer and Cell Metabolism—2nd Edition

edited by

Maria Concetta Faniello

Maria Mesuraca

and

Barbara Quaresima

submission deadline 30 Jun 2025 | 1 articles | Viewed by 558 | Submission Open

Keywords: cell metabolism; cancer metabolism; cancer cell; oxidative stress; gene expression; signaling pathways; metabolic regulation; tumor growth; energy metabolism; metabolic phenotype; metabolic substrates

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Biology of Fish Stress

edited by

Tao Yin

Yong Long

and

Min Jin

submission deadline 30 Jun 2025 | 1 articles | Viewed by 541 | Submission Open

Keywords: fish stress; molecular biology; omics; apoptosis; inflammation

(This special issue belongs to the Section Molecular Biology)

Viral Diseases of the Respiratory System—Molecular Mechanisms and Pathogenesis: 3rd Edition

edited by

Andreas Beineke

submission deadline 30 Jun 2025 | 1 articles | Viewed by 517 | Submission Open

Keywords: respiratory diseases; pneumonia; pneumotropic viruses; pathogenesis; host– pathogen interaction; pulmonary pathology; immunopathology; immunity; disease prevention; treatment; zoonotic diseases; antiviral therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ion Transporter-Based Biomarkers for Sperm Quality

edited by

Elisabeth Pinart

submission deadline 30 Jun 2025 | Viewed by 500 | Submission Open

Keywords: ion transporters; sperm quality; cryotolerance

(This special issue belongs to the Section Molecular Biology)

Molecular Advances and Insights in Cancer Genomics

edited by

Masa Tsuchiya

Alessandro Giuliani

and

Kenichi Yoshikawa

submission deadline 30 Jun 2025 | Viewed by 489 | Submission Open

Keywords: biochemistry; biophysics; cancer genomics; cell biology; complex networks; complex systems; data science; development and differentiation; epigenomics; genome computing; higher-order structure of chromatin; multi-omics integration; next-generation sequencing; proteomics; single-cell CRISPR screens; single-cell genomics; transcriptomics; tumor biology

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights: Transitioning Fertility Research from the Laboratory to Clinical Practice

edited by Ekaterini Domali

submission deadline 30 Jun 2025 | Viewed by 481 | Submission Open

Keywords: IVF/ICSI; male infertility; female infertility; fertility outcomes; endocrine disruptors; oxidative and reductive stress; molecular biology; biomarkers; proteomics; metabolomics; and transcriptomics; cell lines; early pregnancy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

DNA Virus Infection: HPV-Related Cancers, Pathology, Biomarkers and Immunotherapy

edited by

Dimitris Tsakogiannis

submission deadline 30 Jun 2025 | Viewed by 467 | Submission Open

Keywords: HPV; molecular diagnostics; HPV ctDNA; cancer; mutations; viral oncogenicity; immunotherapy; biomarkers; oncology; cancer treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ovarian Cancer: Pathogenesis, Biomarkers and Treatment

edited by Alessandro Antonio Buda

submission deadline 30 Jun 2025 | 1 articles | Viewed by 462 | Submission Open

Keywords: ovarian cancer; radiotherapy; diagnosis; prevention; treatment; fertility sparing

(This special issue belongs to the Section Molecular Oncology)

Pancreatic Diseases: Molecular Pathology and Therapeutics

edited by

Maria Ines Vaccaro

submission deadline 30 Jun 2025 | 1 articles | Viewed by 461 | Submission Open

Keywords: pancreatic cancer; acute pancreatitis; chronic pancreatitis; diabetes; inflammation; molecular markers; therapeutic strategies; genetic predispositions; diagnostic tools

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Next-Generation Hydrogels: Innovations in Biofunctionalization and Personalization for Targeted Biomedical Therapies

edited by

Siu Hong Dexter Wong

and Bohan Yin

submission deadline 30 Jun 2025 | Viewed by 449 | Submission Open

Keywords: biofunctionalization hydrogels; personalized hydrogels; smart hydrogel development; 3D/4D bioprinting of hydrogels; AI-driven hydrogel design; dynamic hydrogel systems; hydrogel-based vaccines and immunotherapies; smart hydrogels for controlled release

(This special issue belongs to the Section Macromolecules)

Exploring Natural Products for Antimicrobial Innovation: New Paths and Promising Leads

edited by

Shagufta Perveen

submission deadline 30 Jun 2025 | Viewed by 444 | Submission Open

Keywords: antimicrobial agents; drug resistance; plant-derived compounds; bioactive molecules; phytochemicals; marine natural products; fungal metabolites; novel drug discovery; microbial pathogens; natural product isolation; drug development; biotechnology in antimicrobial research

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Research in Genetic Causes of Adult-Onset Disorders

edited by

Claudio Graziano

submission deadline 30 Jun 2025 | Viewed by 437 | Submission Open

Keywords: ADPKD; cardiomyopathy; CADASIL; amyloidosis; MODY; late-onset hearing impairment; penetrance; adult onset

(This special issue belongs to the Section Molecular Genetics and Genomics)

Green Chemistry Biocatalysis—Advances in the Use of Sustainable Solvents for Biocatalytic Processes

edited by

Rita Craveiro

and

Alexandre Paiva

submission deadline 30 Jun 2025 | Viewed by 427 | Submission Open

Keywords: biocatalysts; enzymes; sustainability; green solvents; biotechnology; biochemical process engineering

(This special issue belongs to the Section Biochemistry)

Cardiovascular Diseases: Molecular Mechanism and Therapeutic Strategies

edited by

Tzong-Shyuan Lee

submission deadline 30 Jun 2025 | 1 articles | Viewed by 427 | Submission Open

Keywords: cardiovascular diseases; vascular; atherosclerosis; heart failure; stroke; oxidative stress; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on the Physiology and Toxicology of Aquatic Animals

edited by Xin Zhang

submission deadline 30 Jun 2025 | Viewed by 424 | Submission Open

Keywords: aquatic ecosystem; physiology of aquatic animals; toxicology of aquatic animals; environmental adaptability; environmental pollutants; ecotoxicology; biomarkers; risk assessment

(This special issue belongs to the Section Molecular Biology)

Intrinsically Disordered Proteins (IDPs): From Structure to Mechanism and Function

edited by

Kyouhoon Han

submission deadline 30 Jun 2025 | Viewed by 421 | Submission Open

Keywords: IDP; NMR; completely unstructured; pre-structured; PreSMo; target binding

(This special issue belongs to the Section Biochemistry)

Retinoids in Ageing and Age-Related Diseases

edited by

Paul L. Chazot

submission deadline 30 Jun 2025 | Viewed by 420 | Submission Open

Keywords: retinoids; retinoic acid; ageing; age-related diseases

(This special issue belongs to the Section Molecular Biology)

New Insight into Radiation Biology and Radiation Exposure

edited by Lynnette Cary

submission deadline 30 Jun 2025 | 1 articles | Viewed by 412 | Submission Open

Keywords: ionizing radiation; radiation biomarkers; radionuclide; medical countermeasure

(This special issue belongs to the Section Molecular Biology)

Molecular Crosstalk in Breast Cancer Progression and Therapies

edited by Giuseppina Daniela Naimo

submission deadline 30 Jun 2025 | Viewed by 400 | Submission Open

Keywords: breast cancer; endocrine therapy; drug resistance; breast tumor microenvironment; targeted therapies; personalized therapies; immunotherapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Pathogenesis of Allergic Diseases: From Mechanisms to Therapeutics

edited by Clinton B. Mathias and Michiko K. Oyoshi

submission deadline 30 Jun 2025 | Viewed by 398 | Submission Open

Keywords: food allergy; allergic mechanisms; asthma; allergic disease; mast cells; ILC2s; Th2 cells; eosinophils; IL-4; IL-33; IL-13

(This special issue belongs to the Section Molecular Immunology)

Wound Repair: From Basic Biology to Tissue Engineering

edited by

Magdalena Paczkowska-Walendowska

submission deadline 30 Jun 2025 | 1 articles | Viewed by 398 | Submission Open

Keywords: wound healing; tissue engineering; biomaterials; regenerative medicine; chronic wounds

(This special issue belongs to the Section Molecular Biology)

Cell Membrane Electroporation and Electroosmosis Mechanisms

edited by

Paulius Ruzgys

submission deadline 30 Jun 2025 | Viewed by 388 | Submission Open

Keywords: nanosecond electroporation; calcium electroporation; small-molecule electrotransfer; abscopal effect; bacterial electroporation; irreversible electroporation; electrochemotherapy; immune response; apoptosis

(This special issue belongs to the Section Biochemistry)

The Role of Fibrinolytic Factors in Disease

edited by

Yosuke Kanno

submission deadline 30 Jun 2025 | Viewed by 385 | Submission Open

Keywords: fibrinolysis; plasminogen; plasmin; α 2-antiplasmin; uPA; uPAR; tPA; PAI-1

(This special issue belongs to the Section Molecular Biology)

Molecular Dynamics Simulations of Nanobubble for Different Applications

edited by

Ebrahim Kadivar

submission deadline 30 Jun 2025 | Viewed by 367 | Submission Open

Keywords: cavitation bubble; nanobubble dynamics; hydrodynamic cavitation; molecular dynamics simulations; laser-induced cavitation bubble; cavitation exploitation

(This special issue belongs to the Section Molecular Nanoscience)

Future Perspectives and Challenges in Molecular Research of Glioma

edited by Shanchun Guo

submission deadline 30 Jun 2025 | Viewed by 366 | Submission Open

Keywords: gliomas; genetic and epigenetic changes; molecular mechanisms; immunotherapy; innovative therapeutic strategies

(This special issue belongs to the Section Molecular Neurobiology)

Multiple Sclerosis: From Molecular Pathology to Novel Therapeutic Approaches

edited by

László Vécsei

and

Masaru Tanaka

submission deadline 30 Jun 2025 | 1 articles | Viewed by 362 | Submission Open

Keywords: progression-independent relapses (PIRAs); smouldering-associated worsening (SAW); lack of new relapses and of new magnetic resonance imaging activity (NEIDA); slowly expanding lesions (SEL); no evidence of smouldering disease activity (NESDA); neurofilament (NfL); glial fibrillary acidic protein (GFAP); patient-reported outcome (PRO); paramagnetic rim lesions (PRLs); relapse-associated worsening (RAW)

(This special issue belongs to the Section Molecular Neurobiology)

Latest Reviews in Molecular Plant Science 2025

edited by

Maoteng Li

and

Jinsong Bao

submission deadline 30 Jun 2025 | Viewed by 339 | Submission Open

Keywords: gene cloning and gene functional analysis; gene editing; QTL mapping; multi-omics integration analysis; agronomically characteristics; plant development; metabolic pathway; biotic and abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Advancing Redox Biomarkers in Pathological Conditions

edited by

Tatiana Armeni

and

Andrea Scirè

submission deadline 30 Jun 2025 | Viewed by 322 | Submission Open

Keywords: redox biomarkers; oxidative stress; oxidative status in pathological condition; antioxidant enzyme levels detection; low molecular weight antioxidant detection; macromolecule oxidation; oxidative PTMs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Cystinosis from Basic to Clinical Research

edited by Francesco Bellomo

submission deadline 30 Jun 2025 | Viewed by 319 | Submission Open

Keywords: cystinosis; kidney; Fanconi syndrome; muscles; eyes; autophagy; bioenergetics; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Molecular Mechanisms and Therapies of Hepatocellular Carcinoma

edited by Lein-Ray Mo

submission deadline 30 Jun 2025 | Viewed by 280 | Submission Open

Keywords: hepatocellular carcinoma (HCC); molecular biology; biomarkers; epigenetic modulators; precision medicine; metabolic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Steatotic Liver Disease: From Bench to Bedside and Back

edited by

Federico Salomone

submission deadline 30 Jun 2025 | Viewed by 252 | Submission Open

Keywords: MASLD; ALD; MetALD; fibrosis; hepatocellular carcinoma; molecular mechanisms; molecular markers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Adult Stem Cell Research

edited by Dongsu Park

submission deadline 30 Jun 2025 | Viewed by 248 | Submission Open

Keywords: tissue-resident stem cells; skeletal stem/progenitor cells; hematopoietic stem cells; tendon/ligament stem cells; musculoskeletal tissue regeneration; stem cell microenvironment; stem cell aging

(This special issue belongs to the Section Molecular Biology)

Structural Characterization and Pharmacological Activity of Natural Compounds

edited by

Ana Amić

submission deadline 30 Jun 2025 | Viewed by 247 | Submission Open

Keywords: natural compounds; bioactive molecules; molecular structure; characterisation; pharmacological activity; biochemical properties; pharmacokinetics; toxicity

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into the Treatment of Metabolic Syndrome and Diabetes

edited by

Igor Kovalchuk

submission deadline 30 Jun 2025 | Viewed by 226 | Submission Open

Keywords: metabolic dysfunction; metabolic disorder; diabetes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Bioactive Compounds in Human Health

edited by

Dorota Gumul

submission deadline 30 Jun 2025 | Viewed by 215 | Submission Open

Keywords: bioactive compounds; antioxidants; food by-products; functional foods; innovative food technologies; molecular food science

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Chitosan: Structural and Chemical Modification, Properties and Application, 2nd Edition

edited by

Joanna Kluczka

submission deadline 30 Jun 2025 | Viewed by 214 | Submission Open

Keywords: chitosan modification; adsorption removal; membrane separation; food preservation; environmental remediation; wastewater treatment; disease treatment; agricultural production; tissue engineering

(This special issue belongs to the Section Macromolecules)

Repetitive DNA

edited by

Eva Šatović-Vukšić

Miroslav Plohl

and

Manuel A. Garrido-Ramos

submission deadline 30 Jun 2025 | 1 articles | Viewed by 212 | Submission Open

Keywords: repetitive DNA sequences; satellite DNA; transposable elements; heterochromatin; centromere; satellitome; repeatome; cytogenetics; phylogenetics; transcription; ChIP; bioinformatics; genome biology; genome evolution

(This special issue belongs to the Section Molecular Genetics and Genomics)

Displaying special issue 901-950 on page 19 of 68.

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