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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Heat Shock Proteins (HSPs): Biological Functions and Mechanisms of Actions

edited by

Soumya Patnaik

and

Gregory Blatch

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1791 | Submission Open

Keywords: heat shock proteins; apoptosis; immune cell activation; stress responses; misfolded proteins; cellular chaperones; cell signaling

(This special issue belongs to the Section Biochemistry)

Molecular Perspectives on the Synthesis and Application of Hydrogel Materials

edited by

Jieping Fan

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1790 | Submission Open

Keywords: hydrogels; molecular basis; polymeric networks; supermolecular chemistry; three-dimensional structure; mechanical strength; rheologic properties; biomaterial

(This special issue belongs to the Section Materials Science)

New Insights into Lactoferrin: 2nd Edition

edited by

Antimo Cutone

and

Giovanni Musci

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1781 | Submission Open

Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability

(This special issue belongs to the Section Molecular Immunology)

Application of Mass Spectrometry and Chromatography in Drug Monitoring

edited by Carsten Müller

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1765 | Submission Open

Keywords: therapeutic drug monitoring; method validation; pharmacometrics; pediatric clinical pharmacology; laboratory developed tests; clinical mass spectrometry; functional tests; isobars; triple quad mass spectrometry; HR-MS; biomarker; drugs of abuse; therapeutic drugs; metabolites

(This special issue belongs to the Section Biochemistry)

Interplay of Metabolism and Inflammation in Gastrointestinal Disease

edited by Marios N. Papadakis and

Stavros P. Papadakos

submission deadline 20 Apr 2026 | Viewed by 1734 | Submission Open

Keywords: gastrointestinal diseases; inflammation; metabolic dysregulation; metabolic processes

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Forest Tree Genetics, Breeding and Environmental Adaption

edited by

Jingli Yang

and

Huiyu Li

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1731 | Submission Open

Keywords: forest trees; genetic breeding; biotic stress; abiotic stress; tree physiology; gene regulation; genetic engineering

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in the Purinergic System

edited by Margarete Dulce Bagatini

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1716 | Submission Open

Keywords: purinergic system; receptors; ectonucleotidases; CD39; CD73; purinergic signaling

(This special issue belongs to the Section Biochemistry)

Functional Proteomics: Insights from Biomedical Applications and Beyond

edited by

Elva Morretta

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1631 | Submission Open

Keywords: functional proteomics; drug discovery; biomedicine; biomarker identification; protein molecular functions; pathway investigation

(This special issue belongs to the Section Molecular Immunology)

Molecular Pathology and Next-Generation Biomarkers in Nephrology

edited by

Marijn Speeckaert

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1604 | Submission Open

Keywords: nephrology; genetic mutations; epigenetics; next-generation biomarkers; proteomics; metabolomics; single-cell sequencing; spatial transcriptomics; liquid biopsy; cfDNA; exosomes; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Neuroimaging

edited by

Chrissa Sioka

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1592 | Submission Open

Keywords: positron emission tomography pulmonary immunology; single photon emission computed tomography; artificial intelligence; neuro-oncology imaging; neurodegenerative disorders imaging; molecular neuroimaging

(This special issue belongs to the Section Molecular Neurobiology)

New Perspectives on Prostate Cancer Occurrence, Diagnosis, and Treatment

edited by

Michele Marchioni

and

Luigi Schips

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1583 | Submission Open

Keywords: prostate cancer; biomarker; diagnosis; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Updates and Advances in the Field of Glioblastomas: Mechanisms, Microenvironment and Treatments

edited by

Samantha Epistolio

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1577 | Submission Open

Keywords: GBM; molecular classification; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

Recent Progress in Extracellular Vesicles

edited by

Regina Golan-Gerstl

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1576 | Submission Open

Keywords: extracellular vesicles (EVs); macrovesicles; exosomes; cell– cell comunication

(This special issue belongs to the Section Molecular Biology)

Molecular Regulatory Mechanisms in the Hypoxic Environment

edited by Irene Filippi

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1569 | Submission Open

Keywords: hypoxia; hypoxia-inducible factors (HIFs); angiogenesis; metabolic adaptation; autophagy; cell survival; chronic obstructive pulmonary disease (COPD); cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Trace Elements, Metals and Bioactive Compounds: Homeostasis and Metabolic Impairment

edited by

Graziantonio Lauria

and

Rosita Curcio

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1569 | Submission Open

Keywords: trace elements; bioactive compounds; metals; human health; human diseases

(This special issue belongs to the Section Biochemistry)

Plants Redox Biology

edited by

Xin Li

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1555 | Submission Open

Keywords: plant– environment interaction; stress physiology; plant redox signaling; plant hormones; plant– pathogen interaction; reactive oxygen species (ROS); reactive nitrogen species (RNS); ascorbate; flavonoid; glutathione

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Studies of Muscle Contraction

edited by

Massimo Reconditi

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1530 | Submission Open

Keywords: muscle contraction; actin; myosin; thin and thick filament; cytoskeletal anchoring protein

(This special issue belongs to the Section Molecular Biophysics)

Selected Papers from the 13th International Conference on Carbonic Anhydrases and Other Research

edited by

Claudiu T. Supuran

and

Óscar López

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1497 | Submission Open

Keywords: metalloenzymes; carbonic anhydrase; inhibitors; activators; pharmacology; SLC-0111; anticancer agents

(This special issue belongs to the Section Biochemistry)

Research on Plant-Microbe Interactions

edited by Lin Chen

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1432 | Submission Open

Keywords: beneficial microbes; rhizosphere; phyllosphere; endosphere; colonization; microbiome; root exudates; communication; secondary metabolites; plant immunity; environmental stress; resistance to plant disease

(This special issue belongs to the Section Molecular Plant Sciences)

Plant Physiology and Molecular Nutrition: 2nd Edition

edited by

Shu Yuan

and

Guijie Lei

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1431 | Submission Open

Keywords: plant nutritional physiology; nutrient signaling; phytohormones; gene regulation network; environment and nutrition crosstalk

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Therapeutic Approaches to Endocrine Disorders

edited by

Gilberta Giacchetti

and

Emanuele-Salvatore Scarpa

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1425 | Submission Open

Keywords: endocrine disorders; osteoporosis; diabetes; obesity; synthetic drugs; nutraceuticals; biomarkers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Future Challenges and Innovation in Gynecological Oncology

edited by

Alejandro Herreros-Pomares

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1392 | Submission Open

Keywords: gynecologic oncology; molecular biomarkers; personalized medicine; ovarian cancer; immunotherapy; tumor microenvironment; drug resistance; translational research

(This special issue belongs to the Section Molecular Oncology)

The Latest Molecular Research on Renal Disease

edited by Niels Henrik Buus and Marco Eijken

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1306 | Submission Open

Keywords: renal disease; chronic kidney disease; renal regeneration; kidney injury

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Liver Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Clare Selden

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1300 | Submission Open

Keywords: liver disease molecular mechanisms treatments for liver disease somatic cell therapy; ATMP medical device molecular approaches; molecular signatures; RNA therapies; “ omics” for liver disease pathobiology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Interplay Between Blood Cells and Cytokines

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1271 | Submission Open

Keywords: blood cells; communication; cytokine; erythrocyte; immunology; inflammation; interplay; leucocyte; platelet; network

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Environmental Influences on Cellular Responses

edited by

Marcus Krüger

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1263 | Submission Open

Keywords: cell/environment interaction; cell signaling; mechanobiology; photobiology; thermobiology; enviromics; cell-cell communication; cell-cell interaction

(This special issue belongs to the Section Molecular Biology)

Molecular Advances in Macroporous, Mesoporous, and Microporous Materials

edited by

Magdalena Laskowska

submission deadline 20 Apr 2026 | 2 articles | Viewed by 1250 | Submission Open

Keywords: functional materials; nanomaterials; nanostructures; molecular systems; porous materials

(This special issue belongs to the Section Materials Science)

Red Blood Cell Dysfunction and Hemodynamic Changes in Inflammation, Infection and Metabolic Disease

edited by Janette Bester

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1249 | Submission Open

Keywords: red blood cell; inflammation; infection; metabolic disease; hemodynamics

(This special issue belongs to the Section Molecular Biology)

Advances in Metabolomics for Animal Health and Nutrition

edited by

María Dolores Llobat Bordes

and

Pablo Jesús Marín-García

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1218 | Submission Open

Keywords: metabolomics; animal health; animal nutrition; biomarkers; mass spectrometry; NMR spectroscopy; precision nutrition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cell Biology & Regenerative Medicine—2nd Edition

edited by

Rivka Ofir

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1207 | Submission Open

Keywords: hiPSC; hES; Crispr; BBB; disease in a dish; neuro-regeneration; pain reliever; scaffold

(This special issue belongs to the Section Molecular Biology)

Genomics, Genetics, and the Future of Fruit Improvement

edited by Zoe Hilioti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1159 | Submission Open

Keywords: fruit traits; genetics; genetic diversity; omics; new breeding techniques; fruit quality; shelf life

(This special issue belongs to the Section Molecular Plant Sciences)

Collagen and Its Derivatives in Tissue Engineering

edited by

István Hornyák

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1149 | Submission Open

Keywords: collagen derivatives; tissue engineering; in vitro experiments; in vivo investigations; material degradation

(This special issue belongs to the Section Biochemistry)

Molecular Insights on Myogenic Progenitors: Regulation of Differentiation

edited by

James M. Holaska

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1146 | Submission Open

Keywords: myogenic progenitors; skeletal muscle; muscle regeneration; myogenesis

(This special issue belongs to the Section Molecular Biology)

Fiber Plants: Genetics and Genomics, Molecular Mechanisms and Potential Applications—Novel Materials, Functional Foods and Beyond

edited by

Jian Zhang

and

Michael Deyholos

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1143 | Submission Open

Keywords: fiber plant; genetics; genomics; bioactive products; natural fibers; fatty acids; medical products; environmental and ecological effects of fiber plants

(This special issue belongs to the Section Molecular Plant Sciences)

Emerging Topics in Macromolecular Crystallography

edited by

Zhongzhou Chen

and

Giuseppe Zanotti

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1130 | Submission Open

Keywords: macromolecular crystallography; structural biology; artificial intelligence; structure determination; molecular mechanism; functions; drug discovery; protein; nucleic acid; carbohydrates

(This special issue belongs to the Section Macromolecules)

Lung Cancer: From Molecular Mechanisms to Novel Therapeutics: 2nd Edition

edited by

Mariacarmela Santarpia

and

Giulia Pasello

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1115 | Submission Open

Keywords: lung cancer; oncogene; targeted therapy; immunotherapy; predictive biomarkers; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Current Advances in the Pathophysiology and Treatment of Multiple Sclerosis and Related Disorders

edited by Natalia Szejko and

Sara Samadzadeh

submission deadline 20 Apr 2026 | Viewed by 1105 | Submission Open

Keywords: multiple sclerosis; MS; central nervous system; pathophysiology; immunological system

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Preimplantation Genetic Testing in Assisted Reproductive Technologies

edited by

Sung Tae Kim

submission deadline 20 Apr 2026 | Viewed by 1076 | Submission Open

Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology

(This special issue belongs to the Section Molecular Genetics and Genomics)

Multiple Sclerosis: From Molecular Mechanisms to Pathophysiology

edited by

Paolo Ragonese

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1072 | Submission Open

Keywords: multiple sclerosis; pathogenesis; blood– brain barrier; cellular pathways; neurodegeneration; biomarkers; gene– environment interaction; astrocytes; glia

(This special issue belongs to the Section Molecular Neurobiology)

The Interaction Between Cell and Virus, 3rd Edition

edited by

Masahiro Fujimuro

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1061 | Submission Open

Keywords: viral replication; gene expression; lytic infection; viral structure; viral assembly; cell signaling pathway; post-translational modification; immune evasion; viral tumorigenesis; antiviral medication

(This special issue belongs to the Section Molecular Microbiology)

Venom Research

edited by Juliana Pavan Zuliani

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1060 | Submission Open

Keywords: venoms; toxins; biological activities; therapeutic potential; molecular mechanism; venomous animals; pharmacological effects

(This special issue belongs to the Section Molecular Toxicology)

Emerging Viral Epidemics

edited by Nikolaos Siafakas

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1059 | Submission Open

Keywords: emerging viruses; diagnostic virology; viral epidemiology; viral evolution; zoonotic infections; public health; surveillance

(This special issue belongs to the Section Molecular Microbiology)

Advances in Molecular Research on Plant-Fungi Interactions

edited by Francisca Sempere-Ferre

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1057 | Submission Open

Keywords: plant– fungi interactions; mycorrhizal symbiosis; fungal pathogens; effector molecules; plant defense mechanisms; signal transduction; secondary metabolites; microbiome interactions; molecular plant biology; host– pathogen dynamics

(This special issue belongs to the Section Molecular Plant Sciences)

Novel Approaches in Drug Discovery: From Natural Products to Therapeutic Innovations

edited by

Kazuhiko Nakadate

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1027 | Submission Open

Keywords: natural product-derived compounds; drug discovery; medicinal chemistry; disease prevention; therapeutic innovation; artificial intelligence in drug discovery; high-throughput screening; omics technologies; drug delivery systems; novel therapeutic strategies

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanism of Sympathetic Nerves in Cardiovascular Diseases and Cancer

edited by

Yutang Wang

submission deadline 20 Apr 2026 | Viewed by 1016 | Submission Open

Keywords: sympathetic nerve activity; adrenergic receptors; renal denervation; heart disease; stroke; atherosclerosis; hypertension; diabetes; metabolic syndrome; cancer

(This special issue belongs to the Section Molecular Neurobiology)

Novel Genotypes and Experimental Advances in Xenotransplantation

edited by Konrad Fischer

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1013 | Submission Open

Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Ovarian Pathologies: Insights into Mechanisms and Therapeutic Strategy

edited by Anna Ptak

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1011 | Submission Open

Keywords: subfertility and infertility; hormonal dysfunction; diminished ovarian reserve (DOR); ovarian cysts; polycystic ovary syndrome (PCOS); primary ovarian insufficiency (POI); ovarian cancer

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Molecular Mechanism in Infertility

edited by

Antonio Simone Laganà

and Andrea Etrusco

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1002 | Submission Open

Keywords: infertility; molecular mechanisms; reproductive biology; genomics; epigenetics; biomarkers; assisted reproductive technologies; transcriptomics; proteomics; environmental factors

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research and Recent Advances of Antimicrobials

edited by

Már Másson

submission deadline 20 Apr 2026 | 1 articles | Viewed by 1001 | Submission Open

Keywords: antibiotic; antibacterial; antifungal; antiviral; chemical synthesis; drug discovery; natural products; small molecules; peptides; proteins; oligosaccharides; polysaccharides; drug delivery; nanoparticles; solutions; gels; formulation; nanoparticles; materials; coat-ings; drug release; structure– activity; mechanism of action; clinical application; veterinary applications; agricultural applications; food preservation

(This special issue belongs to the Section Molecular Pharmacology)

Targeting Cancer Metabolism: From Mechanism to Therapies

edited by

Zisis Kozlakidis

submission deadline 20 Apr 2026 | 1 articles | Viewed by 998 | Submission Open

Keywords: cancer metabolism; metabolic alterations; Warburg effect; metabolic reprogramming; metabolic disorder; mitochondrial dysfunction; mitochondrial dynamics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2801-2850 on page 57 of 69.

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