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Insights in Metabolomics: Chromatography and Mass Spectrometry Applications in Cancer Research

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 64

Special Issue Editor


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Guest Editor
1. Faculdade de Ciências da Vida, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal
2. CQM—Centro de Química da Madeira, Universidade da Madeira, Campus da Penteada, 9020-105 Funchal, Portugal
Interests: analytical methods; metabolomics; cancer biomarkers; diagnosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Metabolomics is transforming molecular cancer research by analyzing small-molecule metabolites to uncover tumor-specific alterations. Chromatography (LC, GC) and mass spectrometry (MS) enable the high-resolution separation and precise identification of cancer-related metabolites, with LC-MS being particularly effective in the detection of subtle metabolic changes. These techniques promote the discovery of biomarker, revealing the metabolic signatures linked to cancer progression, and illuminate oncometabolism, such as TCA cycle disruptions and oncometabolite accumulation. Metabolomics also supports molecular-targeted therapies by identifying metabolic vulnerabilities and enhances precision oncology by predicting individual treatment responses. This Special Issue highlights recent advancements in chromatography- and MS-based metabolomics and their impact on molecular cancer research. By exploring cutting-edge analytical techniques, it aims to improve our understanding of tumor metabolism, biomarker identification, and the development of targeted therapy, fostering innovation in cancer diagnostics and treatments.

Dr. Catarina Luís
Guest Editor

Manuscript Submission Information

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Keywords

  • metabolomics
  • chromatography
  • mass spectrometry
  • molecular oncology
  • cancer pathways
  • precision medicine

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Published Papers

This special issue is now open for submission.
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