International Journal of Molecular Sciences

Exploring UV-Induced Disease: Insights into Mechanisms and Innovative Strategies for Prevention and Therapy

edited by Hui Xu and

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2983 | Submission Open

Keywords: ultraviolet radiation; skin; DNA damage; DNA repair; immunosuppression; inflammatory disease; autoimmune disease; melanoma; non-melanoma skin cancers; genetic susceptibility; chemopre-vention; tumor immunotherapy; skin organoids for UV study; new animal models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biosynthesis and Regulatory Mechanism of Secondary Metabolites in Medicinal Plants: 3rd Edition

edited by

Shanfa Lu

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2811 | Submission Open

Keywords: biosynthetic pathway; epigenetic regulation; high-throughput sequencing; medicinal plant; metabolic engineering; omics; regulatory mechanism; secondary metabolite; synthetic biology; transcription factor

(This special issue belongs to the Section Molecular Plant Sciences)

Extracellular Vesicles in Cancer and Tumor Microenvironment

edited by Celeste Caruso Bavisotto,

Alessandra Maria Vitale

and

Giuseppa D’Amico

submission deadline 30 Sep 2026 | 3 articles | Viewed by 2797 | Submission Open

Keywords: EVs; cancer; tumor cell-derived EVs (TCdEVs); tumor microenvironment (TME); tumor-associated antigens (TAAs)

(This special issue belongs to the Section Molecular Oncology)

Abnormal Production and Structure of Hemoglobin Molecules

edited by Maria Dimopoulou

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2450 | Submission Open

Keywords: hemoglobin; hemoglobinopathies; thalassemias; sickle cell disease; structural hemoglobin variants; alpha globin; beta globin; globin chain genes; unstable hemoglobins; oxygen affinity

(This special issue belongs to the Section Biochemistry)

Advancements and Applications of Phyto-Nanotherapy in Targeted Disease Treatment

edited by

Adewale Fadaka

and

Nicole Remaliah Samantha Sibuyi

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2393 | Submission Open

Keywords: phyto-nanotherapy; medicinal plants; nanoparticles; targeted drug delivery; phytochemicals; phytotherapy; green nanotechnology; chronic diseases; infectious diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroblastoma: Advances in Molecular Pathogenesis and Therapy

edited by Paola Fadda and

Simona Dedoni

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2234 | Submission Open

Keywords: neuroblastoma; molecular pathogenesis; MYCN; ALK; epigenetics; non-coding RNAs; tumor microenvironment; immunotherapy; targeted therapy; precision medicine

(This special issue belongs to the Section Molecular Oncology)

Stress-Related Disorders and Depression: From Molecular Basis to Therapy (3rd Edition)

edited by

Irena Nalepa

and

Agnieszka Zelek-Molik

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2231 | Submission Open

Keywords: psychobiology of stress; depression; posttraumatic stress disorder; anxiety disorders; animal models; biogenic monoamines; glucocorticoids; inflammation; antidepressant and anxiolytic drugs

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanism, Pathogenesis, and Precision Therapeutics in Thyroid Cancer

edited by

Laura Sterian Ward

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2183 | Submission Open

Keywords: thyroid cancer; molecular pathogenesis; driver mutations; tumor microenvironment; targeted therapy; resistance mechanisms; immunotherapy; precision oncology; liquid biopsy; prognostic biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Genetic and Epigenetic Alterations in Age-Related Diseases

edited by

Valerio Caputo

and

Andrea Latini

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2101 | Submission Open

Keywords: genomics; epigenetic modifications; age-related pathologies; neurodegeneration; dysmetabolism; spatial omics; 3D genome; genetic variants; telomere length; mitochondrial DNA; biomarkers

(This special issue belongs to the Section Molecular Neurobiology)

Functional Materials in Photocatalysis: From Design to Application

edited by

Miguel Díaz-Sánchez

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2070 | Submission Open

Keywords: nanostructured materials ; photocatalysis ; catalysis ; green synthesis ; material design ; surface engineering

(This special issue belongs to the Section Materials Science)

Molecular and Cellular Mechanisms of Taste and Smell: From Physiology to Pathology

edited by

Mariano Mastinu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2056 | Submission Open

Keywords: taste; olfaction; taste/smell processing; chemosensory dysfunction; genetic variations; neurodegeneration; perireceptor space; sensory nutrition; hypogeusia and hyposmia

(This special issue belongs to the Section Molecular Biology)

Biomarkers and Mechanisms Guiding Precision Therapy in Lung Cancer

edited by

Jun Hyeok Lim

submission deadline 30 Sep 2026 | 1 articles | Viewed by 2048 | Submission Open

Keywords: lung cancer; precision therapy; biomarkers; molecular mechanisms; treatment resistance; immunotherapy; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oral Squamous Cell Carcinoma: From Pathogenesis to Targeted Therapy

edited by

Giuseppina Campisi

and

Vito Carlo Alberto Caponio

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2007 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; omics; oral squamous cell carcinoma; leukoplakia; biomarkers; tumor microenvironment; immunotherapy; target therapy; HPV; multidisciplinary team

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

State-of-the-Art Immunotherapy for Non-Small-Cell Lung Cancer

edited by

Haris Charalambous

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1983 | Submission Open

Keywords: immunotherapy; checkpoint inhibitors; vaccines; cellular therapies; predictive biomarkers; chemotherapy; angiogenesis inhibitors; radiotherapy; modulation microbiome

(This special issue belongs to the Section Molecular Oncology)

Breaking Barriers in Drug Discovery: Novel Methodologies and Mechanisms of Action

edited by Likun Gong,

Qiuping Qin

and Jing Chen

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1966 | Submission Open

Keywords: new approach methodologies (NAMs); in silico; in vitro; in vivo; in chemico; drug discovery; computational modeling; artificial intelligence (AI); high-throughput screening (HTS); high-throughput imaging (HTI); bioassay; omics; cell cultures; tissue engineering; organ engineering; therapeutic target; mechanism of drug action

(This special issue belongs to the Section Molecular Pharmacology)

Novel Natural Compound for Wound and Tissue Repair and Regeneration: 4th Edition

edited by

Elia Ranzato

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1839 | Submission Open

Keywords: wound repair; tissue regeneration; natural compounds; phytochemicals; molecular mechanisms

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Current Trends and Future Directions in Antimicrobial Peptide Research

edited by

Sara Elsa Aita

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1821 | Submission Open

Keywords: antimicrobial peptides (AMPs); host defense; structure-function; antimicrobial agents; biomedical applications; antibiotic alternatives; antibiotic resistance

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanism in Cardiac Remodeling

edited by Xianming Lin and

Xiaobo Wu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1818 | Submission Open

Keywords: cardiomyopathy; cardiac arrhythmias; ion channel; calcium transient

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic and Molecular Markers in Prostate Cancer

edited by Thaidy Moreno-Rodriguez

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1813 | Submission Open

Keywords: prostate cancer; genetic markers; androgen receptor signaling; molecular biomarkers; therapy resistance mechanisms; liquid biopsy; precision oncology

(This special issue belongs to the Section Molecular Oncology)

Modeling Neurogenesis, Regeneration and Disease from Animal Models

edited by

Kamel Mhalhel

,

Giuseppe Montalbano

and

Sepand Rastegar

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1772 | Submission Open

Keywords: neurogenesis; neural regeneration; animal models; neural stem cells; neurodevelopment; neurodegeneration; molecular mechanisms; disease modeling; nervous system repair, ultrastructure

(This special issue belongs to the Section Molecular Neurobiology)

Nanotechnology-Driven Insights into Plants: Mechanisms, Detection, and Sustainable Control

edited by

Ezzeldin Ibrahim

submission deadline 30 Sep 2026 | Viewed by 1716 | Submission Open

Keywords: nanotechnology; plant–pathogen interactions; plant immunity; nanoparticles; nano-enabled diagnostics; disease management; antimicrobial nanomaterials; nano-biocontrol; sustainable agriculture; phytopathology

(This special issue belongs to the Section Molecular Nanoscience)

Colorectal Cancer—Emerging Trends and Treatment Strategies

edited by Victor Strambu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1700 | Submission Open

Keywords: innovative therapies; colorectal cancer; new therapeutic approach; synchronous tumors

(This special issue belongs to the Section Molecular Oncology)

The Molecular Landscape of Endometrial and Ovarian Dysfunction in Polycystic Ovary Syndrome: Insights into Disease Mechanisms

edited by

Saad Amer

and

Raheela N. Khan

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1677 | Submission Open

Keywords: polycystic ovarian syndrome (PCOS); molecular mechanisms; endometrial dysfunction; ovarian dysfunction; pathophysiology; biomarkers; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pathogenesis of Age-Related Ocular Diseases and Existing Therapies

edited by

Toshiyuki Oshitari

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1644 | Submission Open

Keywords: aging; senescence; diabetic retinopathy; glaucoma; age-related macular degeneration; ischemic retinal and optic nerve diseases; Werner syndrome; genetic disorders; inflammatory diseases; cataract; cellular dysfunction; cell death; axonal degeneration; vascular abnormalities; oxidative stress; inflammatory cytokines; senescence-associated secretory phenotype; autophagy; mitochondrial dysfunction; anti-aging; neuroprotection; regeneration; anti-inflammatory agents; nutrients; gene therapies; cell transplantation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Microbiome–Epigenome Interactions in Early-Life Molecular Programming

edited by

Maria Carmen Collado

and Miljana Zivojin Jovandaric

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1614 | Submission Open

Keywords: early-life programming; microbiome–epigenome axis; DNA methylation; histone modification; microbial metabolites; non-coding RNAs; immune maturation; placental and postnatal development

(This special issue belongs to the Section Molecular Genetics and Genomics)

In Honor of the 76th Birthday of Dr. Rachel Mata Essayag, a Distinguished Pioneer in Natural Products Research in Mexico

edited by

Fernando Calzada

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1608 | Submission Open

Keywords: pharmacognosy; natural products; phytochemistry; diabetes, cancer; diarrhea; viral infections; bacterial infections; drug development; in vivo; ex vivo; in vitro; in silico

(This special issue belongs to the Section Molecular Pharmacology)

Protein Dynamics in Cancer Drug Resistance: Mechanisms and Therapeutic Opportunities

edited by Slovénie Pyndiah

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1512 | Submission Open

Keywords: drug resistance; cancer proteome; protein turnover; post-translational modifications; targeted therapy; stress adaptation

(This special issue belongs to the Section Molecular Oncology)

Integrative Omics Strategies for Biomarker Discovery and Mechanistic Insights into Disease

edited by

Xinxin Song

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1501 | Submission Open

Keywords: integrative omics; biomarker discovery; cancer signaling networks; drug resistance; phosphoproteomics; multi-omics integration; systems biology; translational research

(This special issue belongs to the Section Molecular Informatics)

Advances in Omics Approaches in Chronic Metabolic Diseases

edited by Ramos-López Omar

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1476 | Submission Open

Keywords: chronic metabolic diseases; obesity; diabetes; cardiovascular disease; fatty liver; genomics; epigenomics; metagenomics; metabolomics; proteomics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research on Forensic Odontology, Legal Medicine, and Forensic Sciences

edited by

Ricardo Henrique Alves Da Silva

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1474 | Submission Open

Keywords: forensic odontology; legal medicine; forensic sciences; forensic genetics; human identification; criminal database; quality assurance; age assessment; sex estimation; ancestry; time of death

(This special issue belongs to the Section Molecular Biology)

Mechanisms of Tumor–Immune System Interactions

edited by

Andrés Tittarelli

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1434 | Submission Open

Keywords: oncoimmunology; tumor–immune system interactions; tumor microenvironment; immune evasion; immunotherapy; antitumor immunity

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Nanotechnology for Biomedical Applications

edited by Sofía Municoy

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1413 | Submission Open

Keywords: nanotechnology; nanosensor; drug delivery; regenerative medicine

(This special issue belongs to the Section Molecular Nanoscience)

New Insights in Translational Bioinformatics: 3rd Edition

edited by

Camelia Quek

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1402 | Submission Open

Keywords: translational research; sequencing; single cell; spatial biology; treatment; diagnostics; machine learning; artificial intelligence; model; computational biology

(This special issue belongs to the Section Molecular Informatics)

Pharmacological Research on Autoimmune Disease

edited by

Caio César de Souza Alves

and Sandra Bertelli Ribeiro de Castro

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1323 | Submission Open

Keywords: autoimmune diseases; plant-derived formulations; drug repurposing strategies; nanostructured delivery systems; complementary therapies; inflammatory; immune system; gut–brain axis

(This special issue belongs to the Section Molecular Pharmacology)

Targeting Metabolism, Inflammation, and Oxidative Stress: Novel Therapeutic Approaches in Human Diseases

edited by Kota V. Ramana

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1322 | Submission Open

Keywords: metabolism ; inflammation ; oxidative stress ; diabetes ; aging ; cardiovascular diseases ; gene editing ; stem cell therapy ; next-generation sequencing ; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammatory and Metabolic Biomarkers in Disease Prediction and Prognosis

edited by

Recep Dokuyucu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1314 | Submission Open

Keywords: inflammation; biomarkers; metabolic indices; triglyceride-glucose index; inflammatory ratios; risk stratification; prognosis; cardiovascular diseases; critical care; neuroinflammation; endocrine disorders; composite inflammatory scores; artificial intelligence; personalized medicine; clinical biochemistry

(This special issue belongs to the Section Biochemistry)

New Advances in Plant Disease Resistance

edited by

Michał T. Kwiatek

and

Roksana Bobrowska

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1312 | Submission Open

Keywords: plant disease resistance; durable resistance; chromosome engineering; plant genomics; genome editing; molecular breeding; introgression; quantitative resistance; crop improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Human Papillomavirus and Cellular Pathways

edited by

Marcus Vinícius de Aragão Batista

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1269 | Submission Open

Keywords: human papillomavirus; HPV oncogenesis; E6 and E7 oncoproteins; cellular signaling pathways; viral integration; epigenetics; molecular biomarkers; host susceptibility; cervical cancer; targeted therapy

(This special issue belongs to the Section Molecular Microbiology)

Methodological Advances in Phytochemical Analysis

edited by

Mehmet Yaman

and

Kadir Uğurtan YILMAZ

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1244 | Submission Open

Keywords: advanced phytochemical profiling; high-resolution mass spectrometry; green extraction methodologies; chemometric data processing; bioactive metabolite elucidation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Insights into Aquatic Animal Reproduction, Breeding Strategies and Genetic Improvement

edited by

Jixing Zou

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1243 | Submission Open

Keywords: reproductive biology; aquaculture genetics; fish breeding; genomic selection; marker-assisted selection; genome editing; hybridization; genetic improvement; molecular breeding; sustainable animal production

(This special issue belongs to the Section Molecular Biology)

Molecular Diagnostics and Therapeutic Advances in Hematology: From Mechanisms to Clinical Applications

edited by

Akiyoshi Takami

and

Jorge Luis Espinoza

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1224 | Submission Open

Keywords: hematology; molecular diagnostics; immunology; biomarkers; hematopoietic cell transplantation; bone marrow failure; hematologic malignancies; plasma cell disorders; translational research; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Research on Redox Homeostasis and Oxidative Stress in Health and Disease

edited by

Aleksandra Nikolić-Kokić

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1111 | Submission Open

Keywords: reactive oxygen species; reactive nitrogen species; redox signalling; antioxidant defence systems; antioxidants; ageing; immunity; metabolism disorder; metabolomics; degenerative diseases; cardiovascular diseases; cancer; infectious diseases; oxidative post-translational modifications

(This special issue belongs to the Section Biochemistry)

Neuroimmune Circuitry: Advances in Neuronal Regulation of Immunity

edited by

Roberto De Luca

submission deadline 30 Sep 2026 | Viewed by 1105 | Submission Open

Keywords: neuroimmunology; neuronal circuits; molecular signaling; hypothalamus; autonomic regulation; neuropeptides; GPCR signaling; inflammation; cytokines; transcriptional regulation

(This special issue belongs to the Section Molecular Immunology)

Molecular and Cellular Mechanisms of Muscle Development and Remodelling

edited by

Katya Naliwaiko

and

Matheus Felipe Zazula

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1099 | Submission Open

Keywords: muscle plasticity; nutrient signaling; protein turnover; metabolic flexibility; bioenergetics; redox homeostasis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Glial Cells in Brain and Eye: Emerging Mechanisms and Functions in Health and Disease

edited by

Mario E. Guido

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1088 | Submission Open

Keywords: glial cells; brain & eye (retina); health & disease; neuronal regulation; therapeutic strategies; CNS; glia biology; cellular interactions

(This special issue belongs to the Section Molecular Biology)

Advances in Beta Cells and Insulin Secretion

edited by

Helena Cristina de Lima Barbosa

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1084 | Submission Open

Keywords: beta cell function; insulin secretion mechanisms; diabetes; glycemic control

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Research on Porous Polymers for Advanced Separation and Analytical Applications

edited by

Dmitrij Bondarev

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1074 | Submission Open

Keywords: microporous polymers; molecular imprinting; ion imprinting; separation; porous surfaces; spectroscopy; chromatography

(This special issue belongs to the Section Macromolecules)

Recent Advances in Omics for Cancer Research

edited by

Hassan Ghazal

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1063 | Submission Open

Keywords: cancer; omics; genomics; transcriptomics; proteomics; metabolomics; multi-omics; biomarkers; precision oncology; systems biology

(This special issue belongs to the Section Molecular Oncology)

Computational Methods in Cancer Genomics and Molecular Oncology

edited by

Fabrício Alves Barbosa Da Silva

and Nicolas Carels

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1055 | Submission Open

Keywords: cancer genomics; computational biology; machine learning; precision oncology; multi-omics integration; molecular oncology; bioinformatics; tumor heterogeneity; biomarker discovery; single-cell sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Recent Advances in Benign Hematology

edited by Sirisha Kundrapu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1039 | Submission Open

Keywords: molecular hematology; erythropoiesis; iron metabolism; complement cascade; coagulation pathways; genetic mutations; immune-mediated cytopenias; thrombotic microangiopathies; hematopoiesis; biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

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