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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Venom Research
edited by Juliana Pavan Zuliani
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1177 | Submission Open
Keywords: venoms; toxins; biological activities; therapeutic potential; molecular mechanism; venomous animals; pharmacological effects
(This special issue belongs to the Section Molecular Toxicology)
Fiber Plants: Genetics and Genomics, Molecular Mechanisms and Potential Applications—Novel Materials, Functional Foods and Beyond submission deadline 20 Apr 2026 | 1 articles | Viewed by 1162 | Submission Open
Keywords: fiber plant; genetics; genomics; bioactive products; natural fibers; fatty acids; medical products; environmental and ecological effects of fiber plants
(This special issue belongs to the Section Molecular Plant Sciences)
Lung Cancer: From Molecular Mechanisms to Novel Therapeutics: 2nd Edition submission deadline 20 Apr 2026 | 1 articles | Viewed by 1158 | Submission Open
Keywords: lung cancer; oncogene; targeted therapy; immunotherapy; predictive biomarkers; liquid biopsy
(This special issue belongs to the Section Molecular Oncology)
Emerging Topics in Macromolecular Crystallography submission deadline 20 Apr 2026 | 1 articles | Viewed by 1157 | Submission Open
Keywords: macromolecular crystallography; structural biology; artificial intelligence; structure determination; molecular mechanism; functions; drug discovery; protein; nucleic acid; carbohydrates
(This special issue belongs to the Section Macromolecules)
The Interaction Between Cell and Virus, 3rd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1126 | Submission Open
Keywords: viral replication; gene expression; lytic infection; viral structure; viral assembly; cell signaling pathway; post-translational modification; immune evasion; viral tumorigenesis; antiviral medication
(This special issue belongs to the Section Molecular Microbiology)
Ovarian Pathologies: Insights into Mechanisms and Therapeutic Strategy
edited by Anna Ptak
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1113 | Submission Open
Keywords: subfertility and infertility; hormonal dysfunction; diminished ovarian reserve (DOR); ovarian cysts; polycystic ovary syndrome (PCOS); primary ovarian insufficiency (POI); ovarian cancer
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Multiple Sclerosis: From Molecular Mechanisms to Pathophysiology
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1108 | Submission Open
Keywords: multiple sclerosis; pathogenesis; blood– brain barrier; cellular pathways; neurodegeneration; biomarkers; gene– environment interaction; astrocytes; glia
(This special issue belongs to the Section Molecular Neurobiology)
Current Advances in the Pathophysiology and Treatment of Multiple Sclerosis and Related Disorders
edited by Natalia Szejko and
submission deadline 20 Apr 2026 | Viewed by 1108 | Submission Open
Keywords: multiple sclerosis; MS; central nervous system; pathophysiology; immunological system
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Emerging Viral Epidemics
edited by Nikolaos Siafakas
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1099 | Submission Open
Keywords: emerging viruses; diagnostic virology; viral epidemiology; viral evolution; zoonotic infections; public health; surveillance
(This special issue belongs to the Section Molecular Microbiology)
Novel Approaches in Drug Discovery: From Natural Products to Therapeutic Innovations
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1087 | Submission Open
Keywords: natural product-derived compounds; drug discovery; medicinal chemistry; disease prevention; therapeutic innovation; artificial intelligence in drug discovery; high-throughput screening; omics technologies; drug delivery systems; novel therapeutic strategies
(This special issue belongs to the Section Molecular Pharmacology)
Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy: 2nd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1086 | Submission Open
Keywords: immune checkpoints; targeted therapies; tumor microenvironment; cancer immunology; precision medicine; cell-based cancer therapy
(This special issue belongs to the Section Molecular Immunology)
Advances in Molecular Research on Plant-Fungi Interactions
edited by Francisca Sempere-Ferre
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1084 | Submission Open
Keywords: plant– fungi interactions; mycorrhizal symbiosis; fungal pathogens; effector molecules; plant defense mechanisms; signal transduction; secondary metabolites; microbiome interactions; molecular plant biology; host– pathogen dynamics
(This special issue belongs to the Section Molecular Plant Sciences)
Role of MicroRNAs in Health and Diseases
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1082 | Submission Open
Keywords: miRNA; cancer; biomarkers; function; miRNA target
(This special issue belongs to the Section Molecular Genetics and Genomics)
Bioinspired and Emerging Functionalized Nanostructures for Precision Drug Delivery submission deadline 20 Apr 2026 | 1 articles | Viewed by 1080 | Submission Open
Keywords: nanostructured materials; nanobiomaterials; nanocomposites; drug delivery systems; targeted therapies; controlled release; responsive functionalities; theranostics; biomedical applications; therapeutic innovations; bioinspired nanostructures; personalized medicine
(This special issue belongs to the Section Molecular Nanoscience)
Preimplantation Genetic Testing in Assisted Reproductive Technologies
edited by
submission deadline 20 Apr 2026 | Viewed by 1077 | Submission Open
Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology
(This special issue belongs to the Section Molecular Genetics and Genomics)
Targeting Cancer Metabolism: From Mechanism to Therapies
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1076 | Submission Open
Keywords: cancer metabolism; metabolic alterations; Warburg effect; metabolic reprogramming; metabolic disorder; mitochondrial dysfunction; mitochondrial dynamics
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring Molecular Mechanism in Infertility
edited by and Andrea Etrusco
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1056 | Submission Open
Keywords: infertility; molecular mechanisms; reproductive biology; genomics; epigenetics; biomarkers; assisted reproductive technologies; transcriptomics; proteomics; environmental factors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Sex and Gender Medicine—Physiology: A New Horizon in Human Physiology
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1055 | Submission Open
Keywords: sex and gender; personalized medicine; sex-specific evidence; sex-specific differences
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Genotypes and Experimental Advances in Xenotransplantation
edited by Konrad Fischer
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1050 | Submission Open
Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Hemolytic Anemia: From Molecular Mechanisms to Therapeutic Exploitation
edited by Joan-Lluis Vives-Corrons
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1030 | Submission Open
Keywords: hemolytic anemias; red blood cells; sickle cell disease; targeted therapies; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Research and Recent Advances of Antimicrobials
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1028 | Submission Open
Keywords: antibiotic; antibacterial; antifungal; antiviral; chemical synthesis; drug discovery; natural products; small molecules; peptides; proteins; oligosaccharides; polysaccharides; drug delivery; nanoparticles; solutions; gels; formulation; nanoparticles; materials; coat-ings; drug release; structure– activity; mechanism of action; clinical application; veterinary applications; agricultural applications; food preservation
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanism of Sympathetic Nerves in Cardiovascular Diseases and Cancer
edited by
submission deadline 20 Apr 2026 | Viewed by 1018 | Submission Open
Keywords: sympathetic nerve activity; adrenergic receptors; renal denervation; heart disease; stroke; atherosclerosis; hypertension; diabetes; metabolic syndrome; cancer
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Endocrine Disruptors in Immune Diseases
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 1014 | Submission Open
Keywords: endocrine disruptors; immune disease; cytokine signaling; autoimmunity; immunotoxicity; epigenetic modulation; hormone receptors; inflammation; environmental toxicology; EDC exposure
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Insights in Metabolomics: Chromatography and Mass Spectrometry Applications in Cancer Research submission deadline 20 Apr 2026 | 1 articles | Viewed by 1013 | Submission Open
Keywords: metabolomics; chromatography; mass spectrometry; molecular oncology; cancer pathways; precision medicine
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Artificial Intelligence in Molecular Biomarker Screening
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 968 | Submission Open
Keywords: molecular biomarkers; imaging biomarkers; screening; artificial intelligence; metaverse
(This special issue belongs to the Section Molecular Informatics)
Chemical Elicitors and Microbial Metabolites: Synergistic Mechanisms in Plant Systemic Resistance Induction
edited by Heewan Kang
submission deadline 20 Apr 2026 | 1 articles | Viewed by 960 | Submission Open
Keywords: chemical elicitors; Bacillus spp.; microbial metabolites; amino acids; defense induction; resistance mechanisms
(This special issue belongs to the Section Molecular Plant Sciences)
Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment—2nd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 871 | Submission Open
Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Multidrug Resistance in Cancer: Molecular Mechanisms and Therapeutic Challenges submission deadline 20 Apr 2026 | 1 articles | Viewed by 866 | Submission Open
Keywords: cancer therapy; MultiDrug Resistance (MDR); Pgp; efflux pumps; tumor microenvironment; anticancer drug target; combination therapy; novel anticancer agents
(This special issue belongs to the Section Molecular Biology)
Application and Molecular Mechanisms of Microwaves for Materials Processing
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 854 | Submission Open
Keywords: microwaves; non-ionizing radiation; molecular materials characterizations; molecular materials synthesis; microwave processing and engineering
(This special issue belongs to the Section Materials Science)
Advanced Plant Molecular Responses to Abiotic Stresses: 2nd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 832 | Submission Open
Keywords: abiotic stress responses (heat; drought; salinity; nutrient deficiency; oxygen quality; flooding; light; etc.); genetically modified plants; CRISPR/Cas-mediated stress overcome; microplastic/nanoparticle stresses; bioinformatic studies; miRNAs and other noncoding RNAs involved in abiotic stresses in plants; secondary metabolite synthesis
(This special issue belongs to the Section Molecular Plant Sciences)
Antimicrobial Agents: Natural Products or Synthetic Compounds 2nd Edition
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 826 | Submission Open
Keywords: multidrug resistance; natural antimicrobial agents; synthetic antimicrobial compounds; combination therapy; severe infectious diseases
(This special issue belongs to the Section Molecular Microbiology)
Immune Cell Therapy and Genome Engineering submission deadline 20 Apr 2026 | 1 articles | Viewed by 799 | Submission Open
Keywords: immune cell therapies; regenerative therapy; gene editing technologies; epigenetic modulation; precision medicine; personalized therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Molecular Mechanisms of Neurodegeneration and Neuroinflammation
edited by Marika Lanza and
submission deadline 20 Apr 2026 | 1 articles | Viewed by 785 | Submission Open
Keywords: neuroinflammation; neurodegeneration; mitochondrial dysfunction; oxidative stress; metabolomics; therapeutic strategies
(This special issue belongs to the Section Molecular Biology)
Molecular Insight into Catalysis of Nanomaterials
edited by Dandan Liu
submission deadline 20 Apr 2026 | 1 articles | Viewed by 773 | Submission Open
Keywords: nanomaterial catalyst; thermal catalysis; photocatalysis; electrocatalysis; DFT calculation
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Advances in Assisted Reproductive Technologies
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 725 | Submission Open
Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology; morpho kinetics; in vitro gametogenesis; in vitro oocyte maturation; reproductive tissue cryopreservation; artificial intelligence (AI)
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms in Cardiovascular Disease Progression
edited by Ying-Hsi Lin
submission deadline 20 Apr 2026 | 1 articles | Viewed by 721 | Submission Open
Keywords: cardiovascular disease progression; molecular mechanisms; inflammation; signal transduction; transcriptional and epigenetic regulation; mitochondrial dysfunction; sarcomeric remodeling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Roles of Non-Coding RNAs in Cancer
edited by Amit K. Mitra
submission deadline 20 Apr 2026 | 1 articles | Viewed by 651 | Submission Open
Keywords: lncRNA; miRNA; cancer; genomics; targeted therapy; biomarkers; drug resistance
(This special issue belongs to the Section Molecular Genetics and Genomics)
Emerging Plastic-Related Toxicity: From Environmental Exposure to Human Health submission deadline 20 Apr 2026 | 1 articles | Viewed by 619 | Submission Open
Keywords: (bio)plastic- and (bio)polymer-related toxicity; microplastic and nanoplastic accumulation/degradation in mammals; cell cultures; human health; in vivo models; epigenetics effects; endocrine disruptor properties of bioplastics; plastics and inflammation; plastics in neurodegeneration and neuroinflammation; reproduction; cell metabolism; immunomodulation
(This special issue belongs to the Section Molecular Toxicology)
Functional Food: Bridging the Gap Between Nutrition and Health
edited by Agata Kryczyk-Poprawa and
submission deadline 20 Apr 2026 | 1 articles | Viewed by 590 | Submission Open
Keywords: functional foods; bioactive compounds; molecular targets; personalized nutrition strategies; chronic disease prevention; healthy aging; nutrient interactions
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Evolutionary Genomics in Plants: From Single Gene to Genome
edited by
submission deadline 20 Apr 2026 | 1 articles | Viewed by 589 | Submission Open
Keywords: evolutionary genomics; plant adaptation; genome evolution; crop improvement; bioinformatics; polyploidy
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanisms of Hypertension
edited by Pedro A. José
submission deadline 20 Apr 2026 | Viewed by 579 | Submission Open
Keywords: salt sensitivity; inverse salt sensitivity; epigenetics; genetics; organ-to-organ communication
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
MicroRNAs in Physiology and Pathophysiology
edited by Małgorzata Guz
submission deadline 20 Apr 2026 | 1 articles | Viewed by 557 | Submission Open
Keywords: miRNA; cell physiology; metabolism; cancer; biomarkers; disease; molecular mechanisms; diagnosis; therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Major Histocompatibility Complex Antigens in Disease
edited by Jerzy K. Kulski and Charles E. Larsen
submission deadline 20 Apr 2026 | Viewed by 542 | Submission Open
Keywords: major histocompatibility complex; immune response; human leukocyte antigen (HLA); immune function; disease susceptibility; pathogen resistance; antigenic transposable elements; cancer
(This special issue belongs to the Section Molecular Immunology)
Membrane Channels in Intercellular Communication submission deadline 20 Apr 2026 | 1 articles | Viewed by 541 | Submission Open
Keywords: gap junctions; connexins; innexins; channels; hemichannels; connexin mutations; channel gating; chemical gating; voltage gating; cell– cell coupling; cell-cell uncoupling; cell communication; intercellular communication; calcium; pH
(This special issue belongs to the Section Biochemistry)
Recent Advancements in Studying Biomacromolecule–Ligand Interactions
edited by
submission deadline 20 Apr 2026 | Viewed by 531 | Submission Open
Keywords: biomacromolecule– ligand interaction; X-ray crystallography; nuclear magnetic resonance (NMR) spectroscopy; surface plasmon resonance (SPR); isothermal titration calorimetry (ITC); fluorescence spectroscopy (FS); mass spectrometry (MS); drug discovery
(This special issue belongs to the Section Macromolecules)
Natural Compounds for Skeletal Muscle Health and Regeneration
edited by
submission deadline 20 Apr 2026 | Viewed by 522 | Submission Open
Keywords: skeletal muscle; natural compounds; molecular mechanism; muscle regeneration; computational analysis; experimental analysis
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular and Clinical Advances in Ophthalmic Inflammation, Infection, and Degeneration
edited by Hyun Jin Shin
submission deadline 20 Apr 2026 | Viewed by 516 | Submission Open
Keywords: ophthalmic inflammation; ocular infection; ocular degeneration; molecular mechanisms; translational research
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Exploring the Impact of the Biological Clock on Health and Disease
edited by
submission deadline 20 Apr 2026 | Viewed by 500 | Submission Open
Keywords: circadian rhythm; inflammation; oxidative stress; energy balance; metabolic syndrome; ageing; cancer; diabetes; obesity; entrainment; synchrony; melatonin
(This special issue belongs to the Section Molecular Biology)
Mitochondrial Energy Metabolism in Cells and Tissues
edited by
submission deadline 20 Apr 2026 | Viewed by 454 | Submission Open
Keywords: mitochondria; mitophagy; mitochondrial biogenesis; mitochondrial dynamics; fusion; fission; energy metabolism
(This special issue belongs to the Section Molecular Biology)
Molecular Biology and Chemistry of Mycotoxins and Phytotoxins, 3rd Edition
edited by
submission deadline 20 Apr 2026 | Viewed by 450 | Submission Open
Keywords: aflatoxins; trichothecenes; fumonisins; ochratoxins; host-specific toxins; Alternaria toxins; emerging mycotoxins; biosynthesis; gene cluster; transcriptional regulation; toxicity; modification; ecological role
(This special issue belongs to the Section Molecular Toxicology)
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