Bioplastic-Related Toxicity in Humans: New Insights and Molecular Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 19
Special Issue Editors
Interests: the effects of environmental pollutants on human health; the role of the endocannabinoid system in the processes of carcinogenicity, inflammation, neurogenesis and neuronal differentiation
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Interests: cartilage tissue engineering; mesenchymal stem cells; osteoarthritis; articular cartilage morphology
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Special Issue Information
Dear Colleagues,
Over the past decade, the rise in plastics and their accumulation in the environment has become a public concern. To limit petroleum-based plastic pollution, bioplastics—comprising bio‐based and/or biodegradable polymers—have been publicized as “green” alternatives with the positive connotation of “environmental sustainability”. As technological advancements refine their properties, bioplastics are increasingly permeating industries. However, their rapid integration into daily-use products requires the scientific scrutiny needed to assess their potential implications for human health. New insights are emerging suggesting that exposure to bioplastics and their additives could cause adverse health effects by compromising cell metabolism and inducing oxidative stress, inflammation, and apoptosis in both in vitro systems and animal models. Therefore, this Special Issue welcomes reviews and research papers aiming to assess the acute and chronic toxicity of bioplastics (including micro- and nanoplastics) on human health by analyzing toxic and epigenetic effects, metabolic alterations, and molecular mechanisms of action in human and mammal experimental model systems.
Dr. Antonietta Santoro
Dr. Marta Anna Szychlinska
Guest Editors
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Keywords
- bioplastics and biopolymers -related toxicity
- microplastics and nanoplastics accumulation/degradation in mammals
- cell cultures
- human health
- in vivo models
- epigenetics effects
- endocrine disruptor properties of bioplastics
- bioplastics and inflammation
- bioplastics in neurodegeneration and neuroinflammation
- reproduction
- cell metabolism
- immunomodulation
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