The Role of Endocrine Disruptors in Immune Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 137
Special Issue Editor
Interests: reproductive toxicology; endocrine disruptors; animal anlternative tests; guidelines of toxicology; calcium metabolism; steroid receptors; stem cells in pharmacological and toxicological test
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Endocrine disrupting chemicals (EDCs) are exogenous substances that interfere with the endocrine system, potentially leading to a range of adverse health effects. While reproductive and developmental toxicity have long been central topics in EDC research, recent studies increasingly highlight the immunomodulatory properties of EDCs. These chemicals may affect immune function by altering cytokine production, disrupting immune cell differentiation, or inducing chronic inflammation, thus contributing to autoimmune diseases, hypersensitivity, or immune suppression.
This Special Issue aims to provide a comprehensive overview of how EDCs influence immune-related diseases, encompassing both mechanistic studies and epidemiological evidence. Submissions that explore the pathways through which EDCs modulate immune responses—such as via nuclear receptors, oxidative stress, or epigenetic modifications—are particularly welcome. In vitro and in vivo models, human biomonitoring data, and systems biology approaches are all encouraged. Ultimately, this Issue seeks to expand our understanding of the intersection between endocrine disruption and immune dysregulation, and to support the development of regulatory strategies for EDC management.
Prof. Dr. Eui-Bae Jeung
Guest Editor
Manuscript Submission Information
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Keywords
- endocrine disruptors
- immune disease
- cytokine signaling
- autoimmunity
- immunotoxicity
- epigenetic modulation
- hormone receptors
- inflammation
- environmental toxicology
- EDC exposure
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