Recent Advancements in Studying Biomacromolecule–Ligand Interactions

Dear Colleagues,

The interaction between biomacromolecules (double-stranded DNA, enzymes, or proteins) and ligands (i.e., small compounds or short peptides) can induce some important biological functions. As a key to controlling enzyme activity, ligands can be bound to the enzyme activity site, and the conformational change of the enzyme or protein molecule is immediately triggered and leads to the occurrence or inhibition of the enzyme catalysis reaction. Some techniques such as X-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, surface plasmon resonance (SPR), isothermal titration calorimetry (ITC), fluorescence spectroscopy (FS), and mass spectrometry (MS) have been used to study biomacromolecule–ligand interactions. The latest research and review papers focussed on biomacromolecule–ligand interaction using these methods will be collected as a part of this Special Issue, which will be beneficial in promoting drug discovery and development.

This Special Issue is supervised by Prof. Dr. Guo-Ping Zhou, with Assistant Editor Dr. Bo Lu from the Institute of Biological Science and Technology, Guangxi Academy of Sciences, serving as the Guest Editor (lubo45@126.com).

Prof. Dr. Guo-Ping Zhou
Guest Editor

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