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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Thyroid Cancer: From Pathophysiology to Novel Therapies
edited by Miklós Bodor
submission deadline 25 Feb 2026 | Viewed by 461 | Submission Open
Keywords: thyroid cancer; therapies; cell signaling; biomarker; kinase inhibitors
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Shaping Macrophages Polarization as an Emerging Therapeutic Approach submission deadline 25 Feb 2026 | Viewed by 396 | Submission Open
Keywords: macrophage polarization; M1 macrophages; M2 macrophages; immune modulation; small molecules; therapeutic strategies; inflammation; cancer immunotherapy; drug resistance
(This special issue belongs to the Section Molecular Immunology)
Advanced Molecular Research in Thromboinflammation
edited by Emanuele Valeriani
submission deadline 25 Feb 2026 | Viewed by 359 | Submission Open
Keywords: blood coagulation factors; blood platelets; endothelium; inflammation; thromboinflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Brain Cancers: Molecular Diagnostic and Therapeutic Approaches submission deadline 25 Feb 2026 | Viewed by 338 | Submission Open
Keywords: brain tumors; gliomas; meningiomas; pituitary tumors; molecular diagnosis; liquid biopsy; targeted therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Perspectives in Nanoadsorption
edited by Carmen María Del Hoyo Martinez
submission deadline 25 Feb 2026 | Viewed by 330 | Submission Open
Keywords: nanoadsorption; nanomaterials; molecular mechanism; emerging contaminants removal in pharmaceutical and food industries; X-ray diffraction (XRD); thermal analysis techniques (DSC); Fourier-transform infrared spectroscopy (FTIR); Raman spectroscopy; molecular functionalization in nanoadsorption
(This special issue belongs to the Section Materials Science)
Research on Signal Transduction Mechanisms of Cancer Cells
edited by
submission deadline 25 Feb 2026 | Viewed by 306 | Submission Open
Keywords: signal transduction mechanisms; cancer cell invasion; cancer cell metastasis; tumorigenesis; cell proliferation
(This special issue belongs to the Section Molecular Oncology)
New Advances in Type 2 Diabetes and Its Complications: 2nd Edition
edited by
submission deadline 25 Feb 2026 | Viewed by 270 | Submission Open
Keywords: diabetes type 2; diabetes complications; pathophysiology of type 2 diabetes; new diabetes treatment; cardiovascular disease; stroke; peripheral artery disease; chronic kidney disease; retinopathy; neuropathy; non-alcoholic fatty liver disease in diabetes
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Advancements in Functional Materials
edited by
submission deadline 25 Feb 2026 | Viewed by 216 | Submission Open
Keywords: synthesis of specialty compounds; specialty compounds in functional materials; special applications: self-cleaning; anti-icing; self-healing; biocidal; etc.; properties; special-purpose functional materials
(This special issue belongs to the Section Materials Science)
Obesity: From Cellular Mechanism to Potential Molecular Therapies
edited by
submission deadline 25 Feb 2026 | Viewed by 149 | Submission Open
Keywords: metabolic pathways; gene expression; epigenetics; obesity-related comorbidities; molecular biomarkers; adipogenesis; therapeutic interventions; small molecules; gene therapy/gene editing; obesity and cancer
(This special issue belongs to the Section Molecular Biology)
Endothelial Cells in Vascular Health and Immunity
edited by
submission deadline 25 Feb 2026 | Viewed by 144 | Submission Open
Keywords: endothelial cells; vascular health; cardiovascular disease; kidney disease; lung injury; inflammation; regenerative medicine; molecular therapy
(This special issue belongs to the Section Biochemistry)
Nanocompounds for Drug Delivery submission deadline 25 Feb 2026 | Viewed by 85 | Submission Open
Keywords: nanocompounds; drug delivery systems; targeted delivery; stimuli-responsive nanocarriers; hybrid nanostructures; controlled release; biocompatibility; photodynamic therapy (PDT); photothermal therapy (PTT)
(This special issue belongs to the Section Molecular Nanoscience)
JAK/STAT Pathway in Stem Cell Biology
edited by Willis Li
submission deadline 25 Feb 2026 | Viewed by 70 | Submission Open
Keywords: JAK/STAT signaling; stem cell self-renewal; cellular differentiation; pluripotency; hematopoietic stem cells; signal transduction; cytokine receptors; transcriptional regulation; stem cell niche; regenerative medicine
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Chronic Inflammatory Sinonasal Diseases
edited by Santos Tiago Soares
submission deadline 25 Feb 2026 | Viewed by 68 | Submission Open
Keywords: chronic rhinosinusitis; nasal polyps; type 2 inflammation; sinonasal immunopathology; molecular pathways; host– microbiome interaction; precision medicine; upper airway disease; translational research
(This special issue belongs to the Section Molecular Immunology)
Angiotensin II in Cardiac Fibrosis and Heart Failure
edited by Argyrios S. Ntalianis
submission deadline 25 Feb 2026 | Viewed by 59 | Submission Open
Keywords: angiotensin II; aldosterone; molecular genetics; cardiac remodeling; cardiac fibrosis; cardiomyopathy; heart failure
(This special issue belongs to the Section Molecular Pharmacology)
Advances in the Design, Synthesis, and Characterization of Metal Complexes with Multifaceted Biological Activities
edited by
submission deadline 25 Feb 2026 | Viewed by 59 | Submission Open
Keywords: metal complexes; molecular design; biological activity; structure– activity relationships; therapeutic applications
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Recent Research on Natural Compounds in Cancer Treatment and Prevention submission deadline 25 Feb 2026 | Viewed by 56 | Submission Open
Keywords: natural compounds; bioactive phytochemicals; anticancer therapy; chemoprevention
(This special issue belongs to the Section Molecular Oncology)
Molecular Pathophysiology and Treatments of Diabetes
edited by
submission deadline 26 Feb 2026 | Viewed by 154 | Submission Open
Keywords: diabetes mellitus; molecular pathophysiology; insulin resistance; beta-cell dysfunction; chronic inflammation; epigenetics; metabolic syndrome; SGLT2 inhibitors; GLP-1 receptor agonists; gut microbiota
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Application of Mass Spectrometry and Chromatography in Biomedicine: 2nd Edition
edited by
submission deadline 27 Feb 2026 | Viewed by 529 | Submission Open
Keywords: mass spectrometry; chromatography; LC-MS; GC-MS; biomarker discovery; pharmaceuticals; metabolomics; proteomics; lipidomics
(This special issue belongs to the Section Molecular Biophysics)
Current Trends in Nanophotonics and Molecular-Scale Light Control
edited by Mitradeep Sarkar
submission deadline 27 Feb 2026 | Viewed by 92 | Submission Open
Keywords: nanophotonics; light– matter interaction; metamaterials and 2D materials; photonic crystals; molecular sensing and imaging; quantum and nonlinear optics
(This special issue belongs to the Section Molecular Nanoscience)
Recent Prospects in Neurons
edited by
submission deadline 27 Feb 2026 | Viewed by 88 | Submission Open
Keywords: DNA damage/repair; genetic/epigenetic; 3D genomic; global transcriptome analysis; transgenic animals; neuron polarization/genesis/network; neuro-developmental/psychiatric diseases; brain structures; intelligence/intellectual disability
(This special issue belongs to the Section Molecular Neurobiology)
Lung Diseases Molecular Pathogenesis and Therapy
edited by
submission deadline 28 Feb 2026 | 6 articles | Viewed by 17620 | Submission Open
Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Rare Diseases Biomarkers: 2nd Edition
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 17080 | Submission Open
Keywords: orphan diseases; rare diseases; inborn errors of metabolism; mitochondrial disorders; biomarker discovery
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Cell Signaling Pathways and Signal Transduction
edited by Katsuhiko Muraki and
submission deadline 28 Feb 2026 | 6 articles | Viewed by 15631 | Submission Open
Keywords: Ca2+ signaling; transcriptional and post-transcriptional pathways; growth factors; second messengers; cell metabolism; cell senescence; protein phosphorylation/dephosphorylation; membrane trafficking; cell proliferation; differentiation; and apoptosis; cytokine/chemokine signaling
(This special issue belongs to the Section Biochemistry)
Drug Discovery Based on Natural Products
edited by Woo-kyung Kim
submission deadline 28 Feb 2026 | 6 articles | Viewed by 12045 | Submission Open
Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies
(This special issue belongs to the Section Molecular Pharmacology)
Anti-Cancer Drugs: Natural Products, Synthetic Compounds and Potential Pharmacological Effects and Applications
edited by Kaiqun Ren and Hui Zou
submission deadline 28 Feb 2026 | 3 articles | Viewed by 7971 | Submission Open
Keywords: cancer; natural product; synthetic compounds; mechanism; structural modification; pharmacological action
(This special issue belongs to the Section Molecular Pharmacology)
Plant–Microbe Interactions: 2nd Edition
edited by Jian Jin
submission deadline 28 Feb 2026 | 6 articles | Viewed by 7672 | Submission Open
Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes
(This special issue belongs to the Section Molecular Plant Sciences)
The Molecular Role of Platelets in Human Diseases submission deadline 28 Feb 2026 | 3 articles | Viewed by 5468 | Submission Open
Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis
(This special issue belongs to the Section Molecular Biology)
Blood Cells in Human Health and Disease
edited by Leonid Livshits
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5336 | Submission Open
Keywords: red blood cell; RBC membrane; RBC biophysical properties; RBC rheology; RBC mechanical properties; RBC membrane vesiculation; RBC clearance; RBC in diabetes; hemoglobinopathies; RBC storage TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biochemistry)
Oral Soft Tissue Repair and Oral Diseases: 2nd Edition
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5312 | Submission Open
Keywords: oral medicine; tissue regeneration; lasers; photobiomodulation; periodontology; implant dentistry
(This special issue belongs to the Section Molecular Biology)
Molecular Imaging for Cancer Theranostics
edited by and Kai Bao
submission deadline 28 Feb 2026 | 2 articles | Viewed by 4971 | Submission Open
Keywords: molecular imaging; cancer theranostics; precision medicine; targeted therapy; diagnostic imaging; theranostic agents; multimodal imaging; molecular probes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Advances in Nanomedicine Innovation in Cancer Treatment
edited by Tijani Gharbi
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3773 | Submission Open
Keywords: nanotechnology; nanomedicine; radiotherapy; theragnostic; antibody– drug conjugates (ADCs); drug delivery; radiopharmaceutical; gold nanoparticles; nanoparticle– biomolecule conjugate
(This special issue belongs to the Section Molecular Nanoscience)
Advances in Amyloid Aggregation and Its Inhibition: Implementing Insights from Physiological Conditions submission deadline 28 Feb 2026 | 2 articles | Viewed by 3661 | Submission Open
Keywords: protein aggregation; amyloid; physiological conditions; aggregation inhibition; neurodegenerative diseases; amyloidosis
(This special issue belongs to the Section Molecular Neurobiology)
Anti-Inflammatory and Anti-Oxidant Effects of Extracts from Plants submission deadline 28 Feb 2026 | 3 articles | Viewed by 2727 | Submission Open
Keywords: oxidative stress; inflammation; herbal extracts
(This special issue belongs to the Section Bioactives and Nutraceuticals)
New Insights into the Molecular Pathogenesis of Myeloproliferative Neoplasms submission deadline 28 Feb 2026 | 2 articles | Viewed by 2372 | Submission Open
Keywords: myeloproliferative neoplasms; molecular diagnostic; targeted therapy; biomarkers; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Network Pharmacology: An Emerging Field in Drug Discovery (2nd Edition)
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2168 | Submission Open
Keywords: network pharmacology; machine learning; databases; drug discovery; computer-aided drug design (CADD); data mining
(This special issue belongs to the Section Molecular Pharmacology)
Liquid Biopsies in Oncology—3rd Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 1777 | Submission Open
Keywords: precision oncology; personalized therapy; cancer biomarkers; liquid biopsy; biological fluids; circulating molecules; circulating tumor cells; CTCs; ctDNA; ctRNA; cell-free DNA; cfDNA; NGS; circulating miRNAs; exosomes; extracellular vesicles
(This special issue belongs to the Section Molecular Oncology)
Microbiomes in Human Health and Disease
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1655 | Submission Open
Keywords: microbiome; dysbiosis; commensal bacteria; pathobiont; metabolites; immune modulation; nutrient metabolism; barrier function; health and disease
(This special issue belongs to the Section Molecular Microbiology)
Molecular Advances in Reproduction and Fertility of Aquatic Animals: 3rd Edition
edited by and Hongtuo Fu
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1648 | Submission Open
Keywords: reproduction; aquatic animals; sex determination; gonadal development; steroid hormones; sex-related genes; monosex culture
(This special issue belongs to the Section Molecular Biology)
Viral Infections: Physiology, Pathophysiology, Pathogenesis, Diagnosis and Treatment, 2nd Edition
edited by and Dominika Marta Stygar
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1614 | Submission Open
Keywords: viral infections; virus mutations; molecular diagnostic methods; antiviral drugs/preparations; viral diseases; physiological mechanisms
(This special issue belongs to the Section Molecular Microbiology)
Innovative Technologies in the Study and Understanding of Colorectal Tumorigenesis: Challenges and Opportunities
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1260 | Submission Open
Keywords: colorectal cancer; genetic analysis; gut microbiome; tumor; circulating components; medicine; immunotherapy; proteomics
(This special issue belongs to the Section Molecular Oncology)
Damage to Plants and Microorganisms Caused by Heavy Metal Toxicity
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 1212 | Submission Open
Keywords: metal; oxidative stress; stress response; molecular function; gene regulation; metabolic regulation; signaling pathway
(This special issue belongs to the Section Molecular Plant Sciences)
Melanoma: Molecular Diagnosis and Treatment
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1187 | Submission Open
Keywords: molecular pathology; melanoma; skin cancer; molecular pathway; dermatopathology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Genetic Advances in Neurobiology of Health and Disease
edited by and Katerina Papanikolopoulou
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1086 | Submission Open
Keywords: genomics; proteins; proteomics; signaling
(This special issue belongs to the Section Molecular Neurobiology)
Oral Diseases: Molecular Research and Novel Therapy
edited by
submission deadline 28 Feb 2026 | Viewed by 1077 | Submission Open
Keywords: oral diseases; molecular mechanisms; inflammation and immunity; redox signalling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Current Trends and Future Directions in Antimicrobial Peptide Research
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 950 | Submission Open
Keywords: antimicrobial peptides (AMPs); host defense; structure-function; antimicrobial agents; biomedical applications; antibiotic alternatives; antibiotic resistance
(This special issue belongs to the Section Molecular Biology)
Molecular Biology of Foodborne Pathogens: Genomics, Resistance, and New Perspectives
edited by
submission deadline 28 Feb 2026 | Viewed by 916 | Submission Open
Keywords: foodborne pathogens; antibiotic resistance; virulence factor; virulence genes; gene expression; bioinformatics; whole geomic sequencing
(This special issue belongs to the Section Molecular Microbiology)
Advances in Natural Antioxidants in Human Health and Diseases
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 905 | Submission Open
Keywords: oxidative stress and diseases; antioxidants; natural products
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Cardiovascular and Metabolic Pharmacology
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 887 | Submission Open
Keywords: cardiovascular pharmacology; metabolic pharmacology; hypertension; diabetes; obesity; atherosclerosis; hyperlipidemias; heart failure
(This special issue belongs to the Section Molecular Pharmacology)
New Advances in Amyotrophic Lateral Sclerosis
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 857 | Submission Open
Keywords: genetics and epigenetics; biomarkers; nutrition and metabolism; TDP-43 pathology; advanced model of ALS
(This special issue belongs to the Section Molecular Neurobiology)
New Trends in Diabetes, Hypertension and Cardiovascular Diseases: 4th Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 830 | Submission Open
Keywords: cardiovascular disease; myocardial infarction; stroke; transient ischemic attack; hypertension; diabetes mellitus; atherosclerosis; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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