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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Coronavirus Disease (COVID-19): Pathophysiology (6th Edition)

edited by

Malgorzata Kloc

and

Jacek Z. Kubiak

submission deadline 20 Jun 2026 | 5 articles | Viewed by 13464 | Submission Open

Keywords: SARS-CoV-2; coronavirus; pandemic; viral diseases; pediatrics; inflammation; immune cells; macrophages; pneumonia; vaccines; cytokines; cytokine storm; PIMS; immunity

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Functional Products for Health Prevention and Promotion

edited by

Aneta Koronowicz

submission deadline 20 Jun 2026 | 2 articles | Viewed by 12345 | Submission Open

Keywords: functional foods; food fortification; biofortification; bioactive food ingredients; human nutrition; nutrition and immunity; health prevention; chronic non-communicable diseases; epigenetics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Antioxidant and Antibacterial Properties of Phytochemicals

edited by

Dalia Urbonaviciene

and Vytaute Starkute

submission deadline 20 Jun 2026 | 5 articles | Viewed by 10816 | Submission Open

Keywords: phytochemicals; natural preservatives; antioxidants; antibacterial properties; food; cosmetics; pharmaceuticals; animal feed

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Neurodegenerative Diseases and Inflammation: Pathogenesis, Biomarkers and Treatments

edited by

Luisa Agnello

and Anna Maria Ciaccio

submission deadline 20 Jun 2026 | 3 articles | Viewed by 9800 | Submission Open

Keywords: neurodegeneration; inflammation; biomarkers; Alzheimer’ s disease; molecular mechanism; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Myocardial Disease: Molecular Pathology and Treatments

edited by

Kazufumi Nakamura

submission deadline 20 Jun 2026 | 3 articles | Viewed by 9101 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; amyloidosis; myocarditis; sarcoidosis; genetic abnormalities; immune mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanism of Acute Myeloid Leukemia

edited by

Walter Fiedler

submission deadline 20 Jun 2026 | 4 articles | Viewed by 8958 | Submission Open

Keywords: leukemia; cytokine; signal transduction; apoptosis; immune therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Application of Machine Learning to Molecular Dynamics Simulations

edited by

Isabella Romeo

submission deadline 20 Jun 2026 | 4 articles | Viewed by 8597 | Submission Open

Keywords: molecular dynamics simulations; machine learning; AI in drug discovery; pharmacokinetics prediction; protein folding simulations; toxicity prediction using ML; free energy calculations; virtual screening; protein– ligand interactions; protein– protein interactions

(This special issue belongs to the Section Molecular Informatics)

Molecular Advances in Skin Diseases: 3rd Edition

edited by

Naoko Kanda

submission deadline 20 Jun 2026 | 3 articles | Viewed by 8218 | Submission Open

Keywords: infection; inflammation; molecular; neoplasm; pathogenesis; skin diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Role and Application of Stem Cells in Regenerative Medicine (Volume 5)

edited by

Oriana Trubiani

Francesca Diomede

and

Jacopo Pizzicannella

submission deadline 20 Jun 2026 | 3 articles | Viewed by 7952 | Submission Open

Keywords: mesenchymal stem cells; tissue regeneration; regenerative medicine; immunomodulatory process

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Challenges and Opportunities: Extracellular Vesicles in Biological and Biochemical Processes, 2nd Edition

edited by

Ilaria Giusti

and

Celeste Caruso Bavisotto

submission deadline 20 Jun 2026 | 2 articles | Viewed by 7293 | Submission Open

Keywords: extracellular vesicles; exosomes intercellular; crosstalk liquid biopsy carcinogenesis; cell differentiation tissue; homeostasis; organ remodeling; biomedicine; advanced diagnostics

(This special issue belongs to the Section Molecular Immunology)

Oxidative Stress in Human Diseases

edited by

Galina Nikolova

submission deadline 20 Jun 2026 | 2 articles | Viewed by 7199 | Submission Open

Keywords: inflammation; oxidative stress; free radicals; proteins; lipids; DNA damage; biomarkers

(This special issue belongs to the Section Biochemistry)

Deciphering Molecular Complexity of Pancreatic Cancer

edited by

Dimitrios H. Roukos

submission deadline 20 Jun 2026 | 4 articles | Viewed by 6756 | Submission Open

Keywords: pancreatic cancer; intratumor heterogeneity; bulk and single-cell multiomics; tumor microenvironment; cancer immunotherapy; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

Advances in Cardiac Disease

edited by

Daniela Rossin

submission deadline 20 Jun 2026 | 2 articles | Viewed by 6556 | Submission Open

Keywords: innovative cardiac research; multidisciplinary cardiovascular approaches; advances in cardio-vascular diagnosis; novel cardiac therapies; therapeutic strategies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Natural Products and Synthetic Compounds for Drug Development: 3rd Edition

edited by

Guan-Jhong Huang

submission deadline 20 Jun 2026 | 4 articles | Viewed by 6448 | Submission Open

Keywords: reactive oxygen; anti-inflammation; cancer; infectious diseases; liver diseases; lung disease; kidney disease; cardiac disease; neuro disease

(This special issue belongs to the Section Molecular Pharmacology)

Microglia in Neurological Disorders: Potential Therapeutic Targets and Underlying Mechanisms

edited by

Masashi Tanaka

submission deadline 20 Jun 2026 | 3 articles | Viewed by 6294 | Submission Open

Keywords: cerebral amyloid angiopathy; Alzheimer's disease; amyloid-β fibril formation

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research and Potential Effects of Medicinal Plants

edited by

Guan-Jhong Huang

submission deadline 20 Jun 2026 | 4 articles | Viewed by 6043 | Submission Open

Keywords: medicinal plants; natural products; disease treatment; drug screening; bioassays

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Biology of Soybean

edited by Zhengjun Xia

submission deadline 20 Jun 2026 | 6 articles | Viewed by 6039 | Submission Open

Keywords: soybean; growth and development; disease resistance; nodulation; nolecular mechanism; plant interaction

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances in Biomarkers of Central Nervous System Diseases and Disorders

edited by

David Gurwitz

and

Chiara Villa

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5809 | Submission Open

Keywords: RNA biomarkers; CNS disorders; autism spectrum disorder; precision medicine

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Research in Hematologic Malignancies

edited by

Rachid Lahlil

and

Anne Aries

submission deadline 20 Jun 2026 | 4 articles | Viewed by 5718 | Submission Open

Keywords: therapeutic targets; leukemogenesis; molecular regulation; cancer stem cells; epigenetics; novel biomarkers; non-coding RNA; DNA methylation; chemotherapy and genetic changes; cancer; hematologic malignancies

(This special issue belongs to the Section Molecular Oncology)

Therapeutic Potential of Antioxidants in the Prevention of Human Diseases, 2nd Edition

edited by

Kota V. Ramana

submission deadline 20 Jun 2026 | 3 articles | Viewed by 5567 | Submission Open

Keywords: antioxidants; vitamins; inflammation; cancer; neurological complications; diabetes; flavonoids; natural compounds; cancer; infections; COVID-19

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Micro- and Nanomaterials for Biomedical Applications

edited by

Silvana Alfei

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5426 | Submission Open

Keywords: biomaterials; medical applications; natural and synthetic polymers; tissue engineering; hydrogels; bone cement; drug delivery systems; dendrimers; micro- and nanocomposites; nanotechnology; bioceramics; biopharmaceutics; biosensing

(This special issue belongs to the Section Molecular Nanoscience)

Tissue Engineering Related Biomaterials: Progress and Challenges

edited by

Mihaela Violeta Ghica

Lacramioara Popa

and Cristina Elena Dinu-Pirvu

submission deadline 20 Jun 2026 | 2 articles | Viewed by 5215 | Submission Open

Keywords: biomaterials; tissue engineering; scaffold materials; regenerative medicine; cell– material interactions; tissue regeneration; bioactive materials; nanotechnology in tissue engineering; electrospinning; 3D printing; biodegradable materials; growth factors

(This special issue belongs to the Section Materials Science)

Radiation-Induced DNA Damage and Toxicity

edited by

Mohammad Asif Sherwani

and

Muhammad Maqbool

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4982 | Submission Open

Keywords: radiation; DNA damage; toxicity; immune response

(This special issue belongs to the Section Molecular Biology)

Editorial Board Members’ Collection Series: “Protein Biophysics”

edited by

Vladimir N. Uversky

and

Assaf Friedler

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4829 | Submission Open

Keywords: protein structure and prediction; protein biophysics; protein dynamics; peptide and protein aggregation; protein misfolding; protein folding; protein stability; protein function; posttranslational modifications; intrinsically disordered proteins; protein– ligand interactions; protein– protein interactions; protein– nucleic acid interactions; membrane proteins; liquid– liquid phase separation

(This special issue belongs to the Section Molecular Biophysics)

Advancements in Diagnostic and Preventive Pharmacogenomics

edited by Alireza Tafazoli

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4813 | Submission Open

Keywords: genome profiling; pharmacogenetic analysis; diagnostic pharmacogenomics; pre-emptive pharmacogenomics; advanced genotyping technologies

(This special issue belongs to the Section Molecular Pharmacology)

Glycoconjugates: From Structure to Therapeutic Application

edited by Rosana Ribić

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4675 | Submission Open

Keywords: glycoconjugates (glycoproteins and glycopeptides; glycolipids; proteoglycans); glyconanoparticles; carbohydrate-based therapeutics; glycomics; glycosylation; glycoengineering; glycobiology; synthesis of glycoconjugates; vaccine development; drug delivery; biomarkers; diagnostics; immunotherapy; regenerative medicine; therapeutic applications

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Adipose Tissue Metabolic Function and Dysfunction, 4th Edition

edited by

Federica Mannino

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4576 | Submission Open

Keywords: inflammation; browning; thermogenesis; adipogenesis; diabetes; adipokines; energy storage; insulin resistance; obesity; lipolysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biomarkers for Targeted Therapies

edited by Vija Lavinia

submission deadline 20 Jun 2026 | 5 articles | Viewed by 4344 | Submission Open

Keywords: biomarkers; molecular targeted radiotherapies; prognostic biomarkers; predictive biomarkers; single or composite biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Focus on Metabolic Research Priorities in PCOS

edited by

Jim Parker

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4336 | Submission Open

Keywords: polycystic ovary syndrome; metabolism; insulin resistance; inflammation; hyperandrogenism

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Regenerative Medicine: Molecular Mechanisms Driving Tissue Regeneration and Repair

edited by

Christopher Robinson

and Paul Jordan Christo

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4324 | Submission Open

Keywords: stem cell; cell signaling; immune modulation; extracellular matrix; remodeling; gene regulation; gene editing; growth factors; extracellular vesicles; small molecules

(This special issue belongs to the Section Molecular Biology)

Plant Pathogen Interactions: 3rd Edition

edited by

Sixue Chen

submission deadline 20 Jun 2026 | 1 articles | Viewed by 4176 | Submission Open

Keywords: pathogenicity; plant immunity; pattern-triggered immunity (PTI); effector-triggered immunity (ETI); effectors; avirulent; virulent; biotroph; necrotrophy; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Insights into Plant–Environment Interactions

edited by

Magdalena Pawełkowicz

submission deadline 20 Jun 2026 | 1 articles | Viewed by 4063 | Submission Open

Keywords: vascular biology; floral development; sex expression; fruit development; grafting; source– sink interactions; genetic resources; stress tolerance; molecular breeding; gene regulation; resistance to biotic and abiotic stresses

(This special issue belongs to the Section Molecular Plant Sciences)

Mesenchymal Stem/Stromal Cells: Mechanisms and Applications in Tissue Regeneration

edited by

Daiva Bironaite

submission deadline 20 Jun 2026 | 4 articles | Viewed by 3904 | Submission Open

Keywords: MSC isolation; identification; and viability; MSC differentiation mechanisms; extracellular environment modifications; intracellular signalling systems; cytotoxicity investigations; tissue regeneration mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

MicroRNA (miRNA) Technology in Cancer

edited by

Duncan Ayers

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3852 | Submission Open

Keywords: miRNA; microRNA; cancer; oncology; drug delivery; technology; non-coding RNA

(This special issue belongs to the Section Molecular Oncology)

Crop Biotic and Abiotic Stress Tolerance: 4th Edition

edited by

Fazhan Qiu

submission deadline 20 Jun 2026 | 4 articles | Viewed by 3697 | Submission Open

Keywords: biotic and abiotic stress tolerance; QTL/gene mapping and clones; gene editing; marker-assisted selection; genomic breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances on Solubility and Diffusivity in Water-Based Systems and in Biological Media

edited by

Ana M. Mainar

and

José S. Urieta

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3667 | Submission Open

Keywords: water solubility ; water-solute interactions ; solvation; hydrophobic and hydrophilic effects ; improving water solubility and prediction ; solution of chemicals in biological media ; diffusivity ; drug transport and bioavailability; chemicals diffusivity across biological barriers

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Plant Tolerance to Stress

edited by

Xingguo Li

submission deadline 20 Jun 2026 | 5 articles | Viewed by 3511 | Submission Open

Keywords: plant; genetic breeding; biotic stress; abiotic stress; gene regulation

(This special issue belongs to the Section Molecular Plant Sciences)

25th Anniversary of IJMS: Updates and Advances in "Materials Science" Section

edited by

Miklós Fried

and

Filippo Rossi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3382 | Submission Open

Keywords: nanomaterials; functional polymers; bio-inspired systems; complex intelligent; responsive materials

(This special issue belongs to the Section Materials Science)

DNA Damage Response from Molecular Mechanisms to Cancer Therapy

edited by Luigi Alfano and

Antonio Giordano

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3308 | Submission Open

Keywords: DNA damage response; synthetic lethality; homologous recombination; cancer therapy

(This special issue belongs to the Section Molecular Oncology)

Bioactive Compounds and Their Antioxidant Role: 2nd Edition

edited by Tamara Jurina

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3282 | Submission Open

Keywords: bioactive compounds; antioxidants; polyphenolic compounds; nutraceuticals; phytochemicals; bioavailability; medicine

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms and Signaling Pathways in Neuroinflammatory Disorders

edited by

Martina Schmidt

and

Karim Rafie

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3186 | Submission Open

Keywords: blood– brain barrier; inducible pluripotent stem cells; organoids; scaffolds; neuroinflammation; microglia; mitochondria; endothelial cells; drug screening; virus infections; cryo-EM

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroendocrine Tumors: From Molecular Pathology to Novel Therapeutic Approaches, Including Theranostics

edited by

Behrooz H. Yousefi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3164 | Submission Open

Keywords: neuroendocrine tumors; NETs; molecular pathology; therapeutic strategies

(This special issue belongs to the Section Molecular Oncology)

Molecular Aspects of Reproductive Medicine

edited by Wei Chen

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3042 | Submission Open

Keywords: spermatogenesis; oogenesis; microenvironment; organ interactions; molecular regulation; gametogenesis; signaling pathways; reproductive disorders

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Precision Medicine During Surgery and Postoperative Care

edited by Lukas Andereggen and Markus M. Luedi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2998 | Submission Open

Keywords: genomics & pharmacogenomics; molecular mechanisms of anesthesia; perioperative biomarkers; perioperative care; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

ROS Signalling and Cell Turnover

edited by

Micol Silic-Benussi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2926 | Submission Open

Keywords: metabolism; lipid droplets; nanoparticles; ROS; cancer therapy; redox homeostasis; mitochondria; cell death

(This special issue belongs to the Section Biochemistry)

Pregnancy-Related Complications: From Pathogenesis to Treatment

edited by

Ozlem Guzeloglu-Kayisli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2600 | Submission Open

Keywords: adverse pregnancy outcomes; spontaneous preterm birth; idiopathic preterm birth; preeclampsia; fetal growth restriction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Mechanism in Neuroinflammation Research

edited by

Robert P. Ostrowski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2494 | Submission Open

Keywords: non-coding RNA; nucleic acids; inflammatory cells; inflammatory mediators; neurotransmitters; neuroinflammation; immune cells; neurodegenerative diseases; cerebrovascular diseases; brain tumors

(This special issue belongs to the Section Molecular Neurobiology)

Circulating Biomarkers for the Diagnosis of Cancer

edited by Fernando Luiz Affonso Fonseca

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2472 | Submission Open

Keywords: biomarkers; circulating ; lab methods; diagnosis; screening

(This special issue belongs to the Section Molecular Oncology)

Cancer Biology: From Genetic Aspects to Treatment, 2nd Edition

edited by

Silvia Cantara

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2393 | Submission Open

Keywords: cancer biology; cancer biomarker; cancer progression; cancer metastasis; genetic of cancer

(This special issue belongs to the Section Molecular Oncology)

Extracellular Vesicles: Advances in Multi-Omics

edited by

Leo Kei Iwai

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2349 | Submission Open

Keywords: extracellular vesicles; omics; mass spectrometry; molecular targets; biomarker

(This special issue belongs to the Section Molecular Biology)

Displaying special issue 3001-3050 on page 61 of 67.

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