Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Immunological Control of Vascular Plasticity: Insights into Arteriogenesis, Angiogenesis, and Atherosclerosis

edited by

Elisabeth Deindl

and

Hector A. Cabrera-Fuentes

submission deadline 31 Dec 2025 | Viewed by 204 | Submission Open

Keywords: vascular plasticity; arteriogenesis; angiogenesis; atherosclerosis; immune modulation; inflammation and vascular remodeling; translational vascular immunology; smooth muscle cell-/endothelial cell proliferation; sterile inflammation; collateral artery growth

(This special issue belongs to the Section Molecular Immunology)

Advanced in In Silico Methods for Rational Drug Design and Predictive Toxicology

edited by

Gnanendra Shanmugam

submission deadline 31 Dec 2025 | Viewed by 196 | Submission Open

Keywords: rational drug design; predictive toxicology; molecular modeling; AI in drug discovery; QSAR; molecular docking; ADMET

(This special issue belongs to the Section Molecular Informatics)

Protein-Targeted Therapeutics: Functional Modulation in Disease Pathways

edited by

Sung-Kun (Sean) Kim

submission deadline 31 Dec 2025 | Viewed by 193 | Submission Open

Keywords: protein-targeted therapeutics; proteins inhibitors; ligand binding; conformational changes

(This special issue belongs to the Section Biochemistry)

Systemic Lupus: Molecular Research, New Biomarkers and Novel Therapy

edited by Juan Pablo Mackern-Oberti

submission deadline 31 Dec 2025 | Viewed by 187 | Submission Open

Keywords: lupus; biomarkers; autoimmunity; inflammation; therapy; treatment; endocrine; prolactin; stress; T cell and B cell activation; T cell and B cell proliferation; antigenic immunosuppression

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Synthesis and Structural Studies of Potential Anticancer Drugs

edited by Janusz Madaj

submission deadline 31 Dec 2025 | Viewed by 181 | Submission Open

Keywords: medicinal chemistry; drug discovery; design and synthesis of bioactive compounds; molecular modeling; X-ray crystallography; structure– activity relationships; structure-based drug design

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Mechanisms of Nitric Oxide in Cardiovascular System

edited by

Elena Grossini

submission deadline 31 Dec 2025 | Viewed by 176 | Submission Open

Keywords: heart; nitric oxide; oxidative stress; pathways; protection; therapy; vascular

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Autoimmune Diseases: The Molecular Basis and New Therapies

edited by

Adawi Mohammad

submission deadline 31 Dec 2025 | Viewed by 170 | Submission Open

Keywords: autoimmunity; molecular mechanisms; biologics; immunotherapy; precision medicine

(This special issue belongs to the Section Molecular Immunology)

Molecular and Cellular Basis of Oral Immunology

edited by

Kenichi Kumagai

submission deadline 31 Dec 2025 | Viewed by 167 | Submission Open

Keywords: oral immunology; oral mucosa; immune tolerance; oral microbiome; oral diseases; periodontium; innate immunity; adaptive immunity

(This special issue belongs to the Section Molecular Immunology)

Advances in Stem Cell Biology and Translational Medicine

edited by Yangluowa Qu

submission deadline 31 Dec 2025 | Viewed by 167 | Submission Open

Keywords: stem cell regulation; differentiation; proliferation; self-renewal; stem cell-based therapy; tissue engineering; translational research

(This special issue belongs to the Section Molecular Biology)

Natural Products in Cancer Prevention and Treatment—Second Edition

edited by

Simona Serini

and

Gabriella Calviello

submission deadline 31 Dec 2025 | Viewed by 166 | Submission Open

Keywords: natural products; cancer; therapeutic strategies; novel molecular pathways

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Genetics and Genomics of Neurodevelopmental Disorders

edited by

Elisabetta Bolognesi

and

Franca Rosa Guerini

submission deadline 31 Dec 2025 | Viewed by 163 | Submission Open

Keywords: neurodevelopmental disorders; genetics; molecular biology; biomarkers; epigenetics; precision medicine; rare variants; common variants; artificial intelligence; machine learning

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Mechanisms and Pathophysiology of Peripheral Neuropathies and Neuromuscular Disorders

edited by

Eleonora Galosi

submission deadline 31 Dec 2025 | Viewed by 163 | Submission Open

Keywords: peripheral neuropathies; neuromuscular disorders; small fiber neuropathy; neuropathic pain; nerve regeneration; molecular pathways; next-generation sequencing

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Neuropharmacology in Neurodegenerative Disorders

edited by

Ichiro Kawahata

submission deadline 31 Dec 2025 | Viewed by 162 | Submission Open

Keywords: neuropharmacology; neurodegenerative disorders; cognitive dysfunction; motor dysfunction; drug discovery; neuroprotection; neurogenesis; brain plasticity; biomarkers; AI (artificial intelligence)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Discoveries in Virus–Cytoskeleton Regulation

edited by

Agustín Valenzuela-Fernández

submission deadline 31 Dec 2025 | Viewed by 162 | Submission Open

Keywords: viruses; cytoskeleton dynamics; actin; tubulin and intermediate filaments; infection; pathogenesis; therapies

(This special issue belongs to the Section Molecular Biology)

Molecular Adaptations of Arthropod Vectors to Oxidative Stress

edited by

Francisco José Alves Lemos

submission deadline 31 Dec 2025 | Viewed by 157 | Submission Open

Keywords: oxidative stress; arthropod vectors; molecular adaptation; redox biology; proteomics; stress response mechanisms

(This special issue belongs to the Section Molecular Biology)

Targeted Peptide Drugs for Metabolic Diseases

edited by

Lukasz Buldak

submission deadline 31 Dec 2025 | Viewed by 156 | Submission Open

Keywords: metabolic disorders; peptide drugs; MASLD; receptor targeting; lipid regulation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Gut Microbiota in Human Disease and Health: 2nd Edition

edited by

Silvia Turroni

and

Federica D'Amico

submission deadline 31 Dec 2025 | Viewed by 156 | Submission Open

Keywords: gut microbiota; human disease; human health; omics; microbiota– host interactions; microbiota manipulation

(This special issue belongs to the Section Molecular Microbiology)

Epigenetic Mechanisms in Pain

edited by Hsien-Yu Peng

submission deadline 31 Dec 2025 | Viewed by 153 | Submission Open

Keywords: chronic pain; epigenetics; molecular biomarkers; neural plasticity; ion channel function; synaptic transmission; therapeutic strategies

(This special issue belongs to the Section Molecular Genetics and Genomics)

Micro/Nano-Structure Regulation of Two-Dimensional Materials

edited by

Ning Wang

submission deadline 31 Dec 2025 | Viewed by 153 | Submission Open

Keywords: 2D materials; micro/nano-engineering; structure– property relationships

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms Underlying the Involvement of Cytomegalovirus in the Progression of Multiple Sclerosis

edited by

Marco Miceli

submission deadline 31 Dec 2025 | Viewed by 150 | Submission Open

Keywords: multiple sclerosis; central nervous system; autoimmune; genetic and environmental factors; herpesviruses; CMV; immunopathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cell Penetrating Peptides: Novel Therapeutic Tools for Drug Delivery

edited by

Betty Revon Liu

submission deadline 31 Dec 2025 | Viewed by 150 | Submission Open

Keywords: cell-penetrating peptides; peptide design; drug delivery; controlled and release; clinical applica-tions; penetration mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Cellular, Immune and Molecular Pathways of Injury and Disease in Forensic and Legal Medicine

edited by

Sorin Hostiuc

submission deadline 31 Dec 2025 | Viewed by 149 | Submission Open

Keywords: molecular autopsy; cellular injury pathways; ischemia and hypoxia markers; molecular profiling of fatal injuries; forensic genetics and toxicogenomic

(This special issue belongs to the Section Molecular Biology)

Pathogenesis of Central Nervous System Disorders, Interplay and Multifaceted Role of Glial Cells and Neuroprotective Mechanisms

edited by Matilde Balbi

submission deadline 31 Dec 2025 | Viewed by 148 | Submission Open

Keywords: neurodegenerative disease; CNS disorders; glial cells; glia-cross talk; extracellular vesicles; calcium pathway; neuroinflammation; autophagy; excitotoxicity; glial phenotype

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Anti-Cancer Effects of Natural Products: 2nd Edition

edited by

Moon Nyeo Park

submission deadline 31 Dec 2025 | Viewed by 146 | Submission Open

Keywords: cancer; natural products; herbal medicine; anticancer therapies; metastasis; recurrence; resistance mechanism; novel biomarker

(This special issue belongs to the Section Molecular Pharmacology)

Innovative Approaches to RNA-Based Therapeutics

edited by

Elzbieta Kierzek

submission deadline 31 Dec 2025 | Viewed by 145 | Submission Open

Keywords: RNA therapeutic; RNA drug; antisense therapy; siRNA; delivery; oligonucleotides; mRNA vaccine

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Skin Allergies: Cross-Disciplinary Approaches to Diagnosis and Therapy

edited by

Montserrat Fernández-Guarino

, Belén De la Hoz and

Javier Martínez-Botas

submission deadline 31 Dec 2025 | Viewed by 145 | Submission Open

Keywords: skin allergy; dermatology; allergy management; allergic reaction; topical immune response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Endometrial Cancer: From Molecular Insights to Treatment

edited by Giuseppe Angelico

submission deadline 31 Dec 2025 | Viewed by 144 | Submission Open

Keywords: endometrial cancer; molecular classification; TCGA; precision oncology; immunotherapy; targeted therapy; biomarkers; tumor microenvironment; genomics; personalized medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Biochemical, Genetic, and Molecular Biology Approaches in Human Reproduction

edited by Athanasios Zikopoulos

submission deadline 31 Dec 2025 | Viewed by 142 | Submission Open

Keywords: reproductive biology; infertilit; epigenetics in reproduction; maternal-fetal health; precision medicine

(This special issue belongs to the Section Molecular Biology)

RNA Biology: Unraveling the Complex Interplay Between Proteins and RNAs in Gene Expression and Regulation, 2nd Edition

edited by

Rosemary Kiernan

submission deadline 31 Dec 2025 | Viewed by 140 | Submission Open

Keywords: RNA biology; protein– RNA interplay; gene expression; post-transcriptional modifications; non-coding RNAs

(This special issue belongs to the Section Molecular Genetics and Genomics)

New Therapeutic Strategies for Cystic Fibrosis

edited by Kavisha Arora

submission deadline 31 Dec 2025 | Viewed by 139 | Submission Open

Keywords: cystic fibrosis; CFTR; modulator therapy; non-responder mutations; mRNA therapy; gene editing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Therapeutic Approaches and Novel Targets in Fibrosis Treatment

edited by

Akrivi Chrysanthopoulou

submission deadline 31 Dec 2025 | Viewed by 139 | Submission Open

Keywords: organ fibrosis; tissue fibrosis; regenerative medicine; fibroblasts; chronic inflammation; immune mechanisms; wound healing; injured epithelium or endothelium; epithelial– mesenchymal transformation; treatment; therapies; therapeutic approaches; diagnosis; prognosis; antifibrotic agents

(This special issue belongs to the Section Molecular Immunology)

Molecular Applications of Microbial and Marine-Derived Natural Products with Health Benefits

edited by Simona Negreş

submission deadline 31 Dec 2025 | Viewed by 136 | Submission Open

Keywords: microbial products; marine-derived products; pharmacological activity; key molecules; molecular mechanisms; drug discovery; nutraceuticals; therapy; prophylaxis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Endocrine–Immune Crosstalk in Human Reproductive Health and Pathology

edited by Juan Pablo Mackern-Oberti

submission deadline 31 Dec 2025 | Viewed by 135 | Submission Open

Keywords: T cells; B cells; autoimmune disease; reproduction; immunemodulation; inflammation; endocrinology; lactation

(This special issue belongs to the Section Molecular Immunology)

Molecular Mechanisms and Therapeutic Targets in Brain Tumor Pathogenesis

edited by Mugurel Petrinel Radoi

submission deadline 31 Dec 2025 | Viewed by 135 | Submission Open

Keywords: brain tumors; molecular pathogenesis; glioma biomarkers; tumor microenvironment; neuro-oncology; targeted therapy; translational neuroscience

(This special issue belongs to the Section Molecular Neurobiology)

Advances in Pharmacology for Neuropathic and Chronic Pain Management

edited by

Kuthati Yaswanth

and

Chih-Shung Wong

submission deadline 31 Dec 2025 | Viewed by 133 | Submission Open

Keywords: neuropathic pain; diabetic neuropathy; chronic pain; DPP-4 inhibitors; SGLT2 inhibitors; pain pharmacology; neuroinflammation; glial activation; ion channels; cannabinoids; endogenous peptides; epigenetic modulation; extended-release formulations; drug repurposing; analgesic mechanisms

(This special issue belongs to the Section Molecular Pharmacology)

Hidradenitis Suppurativa: Molecular Mechanisms and Therapeutic Strategies

edited by

Lucas André Cavalcanti Brandão

submission deadline 31 Dec 2025 | Viewed by 129 | Submission Open

Keywords: hidradenitis suppurativa; molecular mechanisms; therapeutic strategies; pathophysiology; autoinflammatory disorders; immunology; dermatology inflammation; skin disease; molecular pathways; targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Emerging Environmental Exposures and Molecular Disruption Mechanisms in Human Health

edited by

David Lozano-Paniagua

submission deadline 31 Dec 2025 | Viewed by 125 | Submission Open

Keywords: environmental exposure; epigenetic; exposome; molecular biomarkers; molecular toxicology

(This special issue belongs to the Section Molecular Toxicology)

Pharmacological Agents for Soft Tissue and Articular Injections: From Mechanisms to Clinical Applications

edited by

Carmelo Pirri

submission deadline 31 Dec 2025 | Viewed by 125 | Submission Open

Keywords: injectable pharmacological agents; musculoskeletal disorders; injection therapies; platelet-rich plasma (PRP); hyaluronic acid

(This special issue belongs to the Section Molecular Pharmacology)

Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants

edited by Chi-Rei Wu and Li-Wei Lin

submission deadline 31 Dec 2025 | Viewed by 124 | Submission Open

Keywords: plants; phenolic profiles; inflammation; cardiovascular disorders; cancer; diabetes; neurodegenerative disorders

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Perspective of Alzheimer’s Disease

edited by

Philippe Poindron

submission deadline 31 Dec 2025 | Viewed by 119 | Submission Open

Keywords: Alzheimer’ s disease; amyloid peptide (toxic conformation); mutations (gamma-secretase); GWAS; risk factors; new treatment (monoclonal antibodies)

(This special issue belongs to the Section Molecular Neurobiology)

Multiple Myeloma: Cancer Therapy and the Tumour Microenvironment

edited by Ruba Al Abdulla

submission deadline 31 Dec 2025 | Viewed by 118 | Submission Open

Keywords: multiple myeloma; cancer resistance; therapeutic strategies; stroma cells; cancer microenvironment; cancer immunity

(This special issue belongs to the Section Molecular Oncology)

Oxidative–Inflammatory Crosstalk in Retinal Pigment Epithelium: Models, Mechanisms, and Modulators

edited by

Min-Yen Hsu

submission deadline 31 Dec 2025 | Viewed by 117 | Submission Open

Keywords: retinal pigment epithelium (RPE); oxidative stress; inflammation; immunometabolism; mitochondrial dysfunction; inflammasome; IL-8/VEGF signaling; heavy-metal toxicity; extracellular vesicles; antioxidant therapy

(This special issue belongs to the Section Molecular Immunology)

RNA-Mediated Post-Transcriptional Regulation in Bacteria Roles of Small RNAs, Small Proteins, and RNA Modifications

edited by Karl M Thompson

submission deadline 31 Dec 2025 | Viewed by 117 | Submission Open

Keywords: bacterial post-transcriptional regulation; small RNAs (sRNAs); small open reading frames (smORFs); RNA modifications; epitranscriptomics

(This special issue belongs to the Section Molecular Biology)

Gene Regulation and Neurotoxicity in Alcohol Related Pathologies

edited by

Stefano Casalotti

submission deadline 31 Dec 2025 | Viewed by 110 | Submission Open

Keywords: alcohol; ethanol; gene expression; neurotoxicity; epigenetics; polymorphisms; neu-rons; glial cell; plasticity

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Engineering in Insoluble Antibacterial Particle for Medical Devices

edited by Ole T. Jensen

submission deadline 31 Dec 2025 | Viewed by 109 | Submission Open

Keywords: antibacterial; quaternary ammonium silica particles; bactericidal mechanism; antibacterial particle; medical devices

(This special issue belongs to the Section Materials Science)

Structural and Functional Analysis of Amino Acids and Proteins: 2nd Edition

edited by

Wenying Yan

submission deadline 31 Dec 2025 | Viewed by 104 | Submission Open

Keywords: protein structure; protein function; amino acids network; deep learning; bioinformatics; protein– protein interaction; drug discovery; biomarker

(This special issue belongs to the Section Molecular Informatics)

Gene Variants and Phenotypic Diversity: Insights into CFTR, SLC Transporters and Disease

edited by Veronique Ladeveze

submission deadline 31 Dec 2025 | Viewed by 102 | Submission Open

Keywords: mutations; polymorphisms; alternative splicing; exon skipping; intron retention; CFTR (ABCC7); cystic fibrosis; SLC16a3; Alzheimer’ s disease; pulmonary and brain cancer

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Advances in Diagnosis and Treatment of Gynaecological Cancers

edited by

Chenhsuan Wu

submission deadline 31 Dec 2025 | Viewed by 101 | Submission Open

Keywords: gynecological oncology; molecular biomarkers; precision medicine; tumor microenvironment; targeted therapy; early detection; immunotherapy; genomic profiling; drug resistance; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Epigenetic and Transcriptional Regulation in Aquaculture: Immunity, Stress and Disease Prevention

edited by

Chan-Hee Kim

submission deadline 31 Dec 2025 | Viewed by 96 | Submission Open

Keywords: epigenetics; transcriptional regulation; trained immunity; DNA methylation; histone modifications; non-coding RNAs; disease prevention; aquaculture

(This special issue belongs to the Section Molecular Genetics and Genomics)

Genome Editing and Biotechnology in Fruit Improvement

edited by Hongxia Miao

submission deadline 31 Dec 2025 | Viewed by 95 | Submission Open

Keywords: fruit improvement; horticultural crops; genome editing; biotechnology; molecular biology; plant genetics

(This special issue belongs to the Section Molecular Plant Sciences)

Displaying special issue 201-250 on page 5 of 65.

Go to page 3 4 5 6 7

Journal Menu

Journal Browser

Special Issues

Further Information

Guidelines

MDPI Initiatives

Follow MDPI