Molecular Mechanisms and Therapeutic Targets in Brain Tumor Pathogenesis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 13
Special Issue Editor
2. Department of Vascular Neurosurgery National, Institute of Neurology and Neurovascular Diseases, 077160 Bucharest, Romania
Interests: neurosurgery
Special Issue Information
Dear Colleagues,
Brain tumors remain among the most challenging conditions in modern medicine due to their complex pathophysiology, limited therapeutic windows, and frequently dismal prognosis. Recent advances in molecular biology, neurogenetics, and translational neuroscience have significantly expanded our understanding of tumor initiation, progression, and therapy resistance. This Special Issue aims to explore cutting-edge research focusing on the molecular mechanisms underlying brain tumor pathogenesis, from genomic and epigenetic alterations to signaling pathways, tumor microenvironment dynamics, and immunological responses.We invite contributions that provide novel insights into the molecular profiles of gliomas, meningiomas, medulloblastomas, and other primary or metastatic brain neoplasms. Articles may address diagnostic and prognostic biomarkers, therapeutic targets, and innovative treatment approaches including immunotherapy, gene editing, and nanotechnology. Both original research and review articles that bridge the gap between basic science and clinical application are highly welcome.We look forward to your valuable contributions that will advance the understanding and management of brain tumors at the molecular level.
Dr. Mugurel Petrinel Radoi
Guest Editor
Manuscript Submission Information
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Keywords
- brain tumors
- molecular pathogenesis
- glioma biomarkers
- tumor microenvironment
- neuro-oncology
- targeted therapy
- translational neuroscience
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