Advances in Pharmacology for Neuropathic and Chronic Pain Management
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 25
Special Issue Editors
Interests: neuropathic pain; diabetic neuropathy; chronic pain; pharmacological therapy; DPP-4 inhibitors; SGLT2 inhibitors; ion channel modulators; neuroinflammation; glial cell activation; neuroimmune interactions; pain signaling pathways; cannabinoid-based therapies; endogenous peptides; epigenetic modulation; extended-release formulations; drug repurposing; analgesic mechanisms; preclinical pain models; clinical trials in pain
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Special Issue Information
Dear Colleagues,
Chronic and neuropathic pain, including diabetic neuropathy, significantly affect quality of life and remain difficult to treat with current therapies. This Special Issue aims to showcase recent advances in pharmacological strategies targeting pain, with a focus on novel mechanisms and emerging therapeutic agents. Topics of interest include the repurposing of metabolic drugs such as DPP-4 inhibitors and SGLT2 inhibitors, as well as investigations into neuroimmune modulation, ion channel regulation, and glial cell targeting. We also welcome research on endogenous peptides, cannabinoid-based therapies, epigenetic modulators, and extended-release drug formulations designed to optimize pain relief and patient adherence. Submissions addressing preclinical models, clinical trials, and mechanistic studies are highly encouraged. Through this Special Issue, we aim to provide a platform for cutting-edge research that advances our understanding of pain pharmacology and informs the development of safer and more effective pain management therapies.
Dr. Kuthati Yaswanth
Prof. Dr. Chih-Shung Wong
Guest Editors
Manuscript Submission Information
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Keywords
- neuropathic pain
- diabetic neuropathy
- chronic pain
- DPP-4 inhibitors
- SGLT2 inhibitors
- pain pharmacology
- neuroinflammation
- glial activation
- ion channels
- cannabinoids
- endogenous peptides
- epigenetic modulation
- extended-release formulations
- drug repurposing
- analgesic mechanisms
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